WO2011028407A1 - Re-epithelialization wound dressings and systems - Google Patents

Re-epithelialization wound dressings and systems Download PDF

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Publication number
WO2011028407A1
WO2011028407A1 PCT/US2010/045735 US2010045735W WO2011028407A1 WO 2011028407 A1 WO2011028407 A1 WO 2011028407A1 US 2010045735 W US2010045735 W US 2010045735W WO 2011028407 A1 WO2011028407 A1 WO 2011028407A1
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WO
WIPO (PCT)
Prior art keywords
tissue
interface layer
layer
epithelialization
facing side
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2010/045735
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English (en)
French (fr)
Inventor
Christopher Brian Locke
Timothy Mark Robinson
Richard Daniel John Coulthard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KCI Licensing Inc
Original Assignee
KCI Licensing Inc
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43625926&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2011028407(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by KCI Licensing Inc filed Critical KCI Licensing Inc
Priority to JP2012526840A priority Critical patent/JP5911066B2/ja
Priority to AU2010289910A priority patent/AU2010289910C1/en
Priority to CN201080037769.0A priority patent/CN102481209B/zh
Priority to EP10747361.3A priority patent/EP2470135B1/en
Priority to CA2771522A priority patent/CA2771522C/en
Publication of WO2011028407A1 publication Critical patent/WO2011028407A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/05—Bandages or dressings; Absorbent pads specially adapted for use with sub-pressure or over-pressure therapy, wound drainage or wound irrigation, e.g. for use with negative-pressure wound therapy [NPWT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/0203—Adhesive bandages or dressings with fluid retention members
    • A61F13/0213—Adhesive bandages or dressings with fluid retention members the fluid retention member being a layer of hydrocolloid, gel forming material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/0203—Adhesive bandages or dressings with fluid retention members
    • A61F13/022—Adhesive bandages or dressings with fluid retention members having more than one layer with different fluid retention characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71—Suction drainage systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/91—Suction aspects of the dressing
    • A61M1/915—Constructional details of the pressure distribution manifold
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/95—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing with sensors for exudate composition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00089—Wound bandages
    • A61F2013/0017—Wound bandages possibility of applying fluid
    • A61F2013/00174—Wound bandages possibility of applying fluid possibility of applying pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00365—Plasters use
    • A61F2013/00536—Plasters use for draining or irrigating wounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00365—Plasters use
    • A61F2013/0054—Plasters use for deep wounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00727—Plasters means for wound humidity control
    • A61F2013/00748—Plasters means for wound humidity control with hydrocolloids or superabsorbers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00855—Plasters pervious to air or vapours
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/98—Containers specifically adapted for negative pressure wound therapy
    • A61M1/984—Containers specifically adapted for negative pressure wound therapy portable on the body
    • A61M1/985—Containers specifically adapted for negative pressure wound therapy portable on the body the dressing itself forming the collection container
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains

Definitions

  • the present disclosure relates generally to medical treatment systems and, more particularly but not by way of limitation, to re-epithelialization wound dressings and systems.
  • the physiological process of wound healing involves different phases that may occur simultaneously or sequentially. As used herein, "or” does not require mutual exclusivity. Two phases of the wound healing process involve granulation (proliferation) and re-epthiliazation.
  • a re-epithelialization dressing for use with reduced pressure includes a moist tissue-interface layer, a manifold member, and a sealing member.
  • the moist tissue-interface layer is adapted to provide a moisture balance for the tissue and is formed with a plurality of apertures.
  • the manifold is operable to distribute reduced pressure and is disposed between the sealing member and the moist tissue-interface layer.
  • a system for promoting re-epithelialization of a wound includes a re-epithelialization wound dressing.
  • the re-epithelialization wound dressing includes a moist tissue-interface layer, a manifold member, and a sealing member.
  • the moist tissue-interface layer is adapted to provide a moisture balance for the tissue and is formed with a plurality of apertures.
  • the manifold is operable to distribute reduced pressure and is disposed between the sealing member and the moist tissue-interface layer.
  • the system further includes a reduced-pressure connector, a reduced-pressure delivery conduit, and a reduced-pressure source to provide reduced pressure to the re-epithelialization wound dressing.
  • the reduced-pressure delivery conduit is operable to fluidly couple the reduced-pressure source to the reduced-pressure connector.
  • a method for promoting re-epithelialization of a wound includes the steps of: deploying a re- epithelialization dressing proximate the wound; fluidly coupling a reduced-pressure delivery conduit to the re-epithelialization dressing; and providing reduced pressure to the reduced- pressure delivery conduit.
  • the re-epithelialization dressing includes a moist tissue-interface layer operable to provide a moisture balance.
  • the moist tissue-interface layer has a first side and a second, tissue- facing side and is formed with a plurality of apertures.
  • the re- epithelialization dressing further includes a manifold member for distributing reduced pressure.
  • the manifold member has a first side and a second, tissue-facing side.
  • the re- epithelialization dressing also includes a sealing member, which has a first side and a second, tissue-facing side.
  • the manifold member is disposed between the sealing member and the moist tissue-interface layer.
  • FIGURE 1 is a schematic diagram with a portion in cross section of an illustrative, non-limiting embodiment of a system for treating a wound
  • FIGURE 2 is a schematic detail of a portion of the illustrative, non-limiting embodiment of a system for treating a wound of FIGURE 1 shown without reduced pressure applied;
  • FIGURE 3 is a schematic detail of a portion of the illustrative, non-limiting embodiment of a system for treating a wound of FIGURE 1 shown with reduced pressure applied;
  • FIGURE 4 is a schematic detail of a portion of the illustrative, non-limiting embodiment of a system for treating a wound of FIGURE 1 shown with an absorber layer added.
  • a wound treatment system 100 which includes a re-epithelialization dressing 102
  • the re-epithelialization dressing 102 is shown deployed for treatment on a tissue site 104 and in particular a wound 106, or wound site.
  • the wound 106 is shown extending through epidermis 108 and into subcutaneous tissue 110.
  • the tissue site 104 may be the bodily tissue of any human, animal, or other organism, including bone tissue, adipose tissue, muscle tissue, dermal tissue, vascular tissue, connective tissue, cartilage, tendons, ligaments, or any other tissue.
  • the wound treatment system 100 with the re-epithelialization dressing 102 promotes re-epithelialization of the wound 106 and may encourage migration of wound edges 112.
  • the re-epithelialization, or epithelialization, phase of acute wound healing involves resurfacing of the wound 106 and changes in the wound edges 1 12.
  • the process protects a patient's body from invasion by outside organisms and may occur concurrently with other phases if not restricted.
  • the resurfacing aspect involves keratinocytes.
  • keratinocytes form layers of the dermis and epidermis. Keratinocytes are derived from epidermal stem cells located in the bulge area of hair follicles and migrate from that location into the basal layers of epidermis. The keratinocytes proliferate and differentiate to produce epidermis and thereby replenish the epidermis.
  • Keratinocytes may respond to signals released from growth factors, which may be in wound exudate, by advancing in a sheet to resurface a space. Because of this migration, a moist wound environment may speed or otherwise facilitate the migration of keratinocytes toward one another from the wound edges 112. The wound treatment system 100 promotes this re- epithelialization phase or process.
  • the wound treatment system 100 includes a reduced-pressure connector 1 14 that may be associated with the re-epithelialization dressing 102 for providing reduced pressure to at least a portion of the re-epithelialization dressing 102.
  • a reduced-pressure delivery conduit 116 may be fluidly coupled to the reduced-pressure connector 114 at a first end 1 18 and fluidly coupled to a reduced-pressure source 120 at a second end 122.
  • One or more devices 124 may be fluidly coupled between the reduced-pressure connector 114 and the reduced-pressure source 120, such as on the reduced-pressure delivery conduit 1 16.
  • the device or devices 124 that may be fluidly coupled to the reduced-pressure delivery conduit 1 16 include, for example, without limitation, a fluid reservoir (or collection member, to hold exudates and other fluids removed), a pressure-feedback device, a volume detection system, a blood detection system, an infection detection system, a flow monitoring system, a temperature monitoring system, or other device.
  • the reduced-pressure source 120 provides reduced pressure as a part of the wound treatment system 100.
  • reduced pressure generally refers to a pressure less than the ambient pressure at the tissue site 104 that is being subjected to treatment. In most cases, this reduced pressure will be less than the atmospheric pressure at which the patient is located. Alternatively, the reduced pressure may be less than a hydrostatic pressure of tissue at the tissue site 104.
  • vacuum and “negative pressure” may be used to describe the pressure applied to the tissue site, the actual pressure applied to the tissue site may be significantly more than the pressure normally associated with a complete vacuum. Unless otherwise indicated, values of pressure stated herein are gauge pressures.
  • the reduced pressure delivered by the reduced-pressure source 120 may be constant or varied (patterned or random) and may be delivered continuously or intermittently.
  • the reduced-pressure source 120 may be a battery-powered, reduced-pressure generator. This facilitates application in the operating room and provides mobility and convenience for the patient during the rehabilitation phase.
  • Other sources of reduced pressure may be utilized, such as V.A.C. ® therapy unit, which is available from KCI of San Antonio, Texas, wall suction, or a mechanical unit.
  • the reduced pressure developed by the reduced-pressure source 120 is delivered through the reduced-pressure delivery conduit 116, or medical conduit or tubing, to the reduced-pressure connector 114.
  • An interposed hydrophobic membrane filter may be interspersed between the reduced-pressure delivery conduit 1 16 and the reduced-pressure source 120.
  • the reduced- pressure source may be contained within the re-epithelialization dressing 102 and may be, for example, a micro-pump.
  • the re-epithelialization dressing 102 may include a plurality of layers or materials.
  • the re-epithelialization dressing 102 may include a moist tissue-interface layer 126, a support layer 128, a manifold member 130, and a sealing member 132.
  • the sealing member 132 may be formed with a connector aperture 134 through which at least a portion of the reduced-pressure connector 1 14 extends.
  • the reduced-pressure connector 114 is shown disposed in part between the sealing member 132 and the manifold member 130 and with a portion extending through the connector aperture 134.
  • the re- epithelialization dressing 102 may have additional layers or fewer layers and the layers may be placed in differing combinations in some embodiments.
  • the moist tissue-interface layer 126 has a first side 136 and a second, tissue- facing side 138.
  • the moist tissue-interface layer 126 is formed with a first plurality of apertures 140, which may take any shape.
  • the first plurality of apertures 140 extend through the moist tissue-interface layer 126.
  • the first plurality of apertures 140 may be formed with a laser, punched, drilled, or formed by casting, or any other technique.
  • the first plurality of apertures 140 may be formed with a uniform pattern or may be random and may have uniform or varied diameters.
  • the first plurality of apertures 140 are formed with a uniform pattern with aperture centers 141 being formed with a distance 142 between adjacent aperture centers 141.
  • the distance 142 is about two millimeters, three millimeters, four millimeters, five millimeters, six millimeters, seven millimeters, eight millimeters, nine millimeters, ten millimeters, or more.
  • the distance 142 may be selected for the desired liquid transmission through the moist tissue- interface layer 126.
  • the diameter of the first plurality of apertures 140 may also be selected so that when reduced pressure is applied and saturation occurs (at least in some embodiments), the first plurality of apertures 140 will not firmly collapse and seal but will become restricted to allow liquid to pass but to generally restrict the passing of gases through the first plurality of apertures 140. In other embodiments, the first plurality of apertures 140 may be sized to allow the first plurality of apertures 140 to close completely and firmly under the influence of reduced pressure. [0024]
  • the moist tissue- interface layer 126 may be made from numerous materials.
  • the moist tissue-interface layer 126 may be, for example, a water-based material, such as a hydrogel or hydrocolloid.
  • the material from which the moist tissue-interface layer 126 is formed provides a fluid balance, or equilibrium, with respect to a desired moist condition.
  • the material may provide moisture when needed (i.e., the tissue site 104 is dry) and will absorb moisture when needed (i.e., excessive moisture exists at the tissue site 104 or the tissue site 104 is substantially wet).
  • the second, tissue-facing side 138 may be a relatively smooth surface as compared to a micro-strain inducing material, such as an open- cell foam.
  • the relatively smooth surface of the second, tissue-facing side 138 helps to promote (or at least not hinder) cell migration.
  • the relatively smooth surface of the second, tissue- facing side 138 may create little or no local micro-strain.
  • the moist environment provided by the moist tissue-interface layer 126, fluid management of the first plurality of apertures 140, and the relatively smooth surface of the second, tissue-facing side 138 may encourage re-epithelialization of the wound 106.
  • the moist tissue-interface layer 126 may be used for other materials, such as a very dense hydrophilic foam (e.g., a hydrophilic closed cell foam); a film-coated, perforated, non-woven material; a hydrogel-impregnated foam; a hydroactive dressing material, or other material.
  • the hydrogel-impregnated foam may be particularly well suited for deeper wounds or difficult shapes.
  • the moist tissue-interface layer 126 may be perforated or cut into sections that allow removal of one or more portions of the moist tissue-interface layer 126 in order to provide reduced pressure to a portion or the tissue site 104. An opening created by the removed section may help with a highly exudating wound or may promote granulation if desired in an area of the wound 106.
  • the moist tissue-interface layer 126 will typically swell as the moist tissue-interface layer 126 receives fluid under reduced pressure. With sufficient fluid, the moist tissue-interface layer 126 may become saturated. As shown in FIGURE 3, the first plurality of apertures 140 may substantially swell to a restricted position, or state, as compared to the open position, or state, of FIGURE 2. The restricted position occurs when the moist tissue-interface layer 126 is substantially saturated. In the restricted position, the first plurality of apertures 140 will allow liquid to pass from the tissue site 104 through the first plurality of apertures 140 but will not substantially communicate reduced pressure through the first plurality of apertures 140.
  • re-epithelialization dressing 102 will remove fluid from the first side 136 of the moist tissue-interface layer 126 once the moist tissue- interface layer 126 becomes saturated or substantially saturated. Some liquids or moisture, e.g., exudates, will remain at the wound 106 and may possibly assist in the healing process by providing signals.
  • the re-epithelialization dressing 102 may include an optional support layer 128.
  • the support layer 128 has a first side 144 and a second, tissue-facing side 146.
  • the second, tissue-facing side 146 is disposed adjacent to the first side 136 of the moist tissue- interface layer 126.
  • the moist tissue-interface layer 126 and the support layer 128 may be coupled.
  • the term “coupled” includes coupling via a separate object and includes direct coupling.
  • the term “coupled” also encompasses two or more components that are continuous with one another by virtue of each of the components being formed from the same piece of material.
  • the term “coupled” may include chemical, such as via a chemical bond, mechanical, thermal, or electrical coupling.
  • the term “coupled” may include any known technique, including, without limitation, welding (e.g., ultrasonic or RF welding), bonding, adhesives, cements, or other techniques or devices. Fluid coupling means that fluid is in communication between the designated parts or locations
  • the support layer 128 is optional but may be added to provide support for the moist tissue-interface layer 126. As shown best by comparing FIGURES 2 and 3, the support layer 128 may help hold a first end 148 of the first plurality of apertures 140 in an open position or with a set diameter while other portions may be further restricted as part of the restricted state.
  • the support layer 128 may be formed from numerous materials, such as an occlusive film material.
  • the support layer 128 may be, for example, a polyurethane layer, a polyethylene layer, or other support material.
  • the support layer 128 may help direct fluid flow and provide support, particularly for the first plurality of apertures 140, as previously mentioned.
  • the support layer 128 may be formed with a second plurality of apertures 150.
  • the second plurality of apertures 150 may align and correspond with the first plurality of apertures 140.
  • the second plurality of apertures 150 may be formed in the same or similar manner as the first plurality of apertures 140.
  • the re-epithelialization dressing 102 includes the manifold member 130.
  • the manifold member 130 has a first side 152 and a second, tissue-facing side 154.
  • the manifold member 130 may be formed from any material that distributes fluids, including reduced pressure.
  • the term "manifold” as used herein generally refers to a substance or structure that is provided to assist in applying reduced pressure to, delivering fluids to, or removing fluids from a tissue site 104.
  • the manifold member 130 typically includes a plurality of flow channels or pathways that distribute fluids provided to and removed from the tissue site 104 around the manifold member 130. In one illustrative, non-limiting embodiment, the flow channels or pathways are interconnected to improve distribution of fluids provided or removed from the tissue site 104.
  • the manifold member 130 may include, for example, without limitation, devices that have structural elements arranged to form flow channels, such as, for example, cellular foam, open-cell foam, porous tissue collections, liquids, gels, and foams that include, or cure to include, flow channels.
  • the manifold member 130 may be porous and may be made from foam, gauze, felted mat, or any other material suited to a particular biological application.
  • the manifold member 130 is a porous foam and includes a plurality of interconnected cells or pores that act as flow channels.
  • the porous foam may be a polyurethane, open-cell, reticulated foam, such as GranuFoam® material manufactured by Kinetic Concepts, Incorporated of San Antonio, Texas. Other embodiments may include "closed cells.”
  • a manifold member 130 is formed of a non-woven material, such as a non-woven material available from Libeltex BVBA of Belgium.
  • the second, tissue-facing side 154 of the manifold member 130 is disposed adjacent to the first side 144 of the support layer 128 in one illustrative, non-limiting embodiment or adjacent to the first side 136 of the moist tissue-interface layer 126 in another illustrative, non-limiting embodiment.
  • the re-epithelialization dressing 102 includes the sealing member 132.
  • the sealing member 132 has a first side 158 and a second, tissue-facing side 160.
  • the sealing member 132 forms a sealed space over the tissue site 104 or wound 106.
  • the second, tissue- facing side 160 is disposed adjacent to and may be coupled to the first side 152 of the manifold member 130 or another layer.
  • the sealing member 132 may be formed from any material that provides a fluid seal. "Fluid seal,” or "seal,” means a seal adequate to maintain reduced pressure at a desired site given the particular reduced-pressure source or subsystem involved.
  • the sealing member may, for example, be an impermeable or semi-permeable, elastomeric material.
  • Elastomeric means having the properties of an elastomer.
  • Elastomeric generally refers to a polymeric material that has rubber-like properties. More specifically, most elastomers have ultimate elongations greater than 100% and a significant amount of resilience. The resilience of a material refers to the material's ability to recover from an elastic deformation.
  • elastomers may include, but are not limited to, natural rubbers, polyisoprene, styrene butadiene rubber, chloroprene rubber, polybutadiene, nitrile rubber, butyl rubber, ethylene propylene rubber, ethylene propylene diene monomer, chlorosulfonated polyethylene, polysulfide rubber, polyurethane, EVA film, co-polyester, and silicones.
  • sealing member materials include a silicone drape, 3M Tegaderm® drape, acrylic drape, such as one available from Avery Dennison, or an incise drape.
  • the re-epithelialization dressing 102 may have an optional absorbent layer 162, or absorber, disposed between the sealing member 132 and the manifold member 130 or other layers.
  • the absorbent layer 162 has a first side 164 and a second, tissue- facing side 166.
  • the first side 164 may be coupled to the second, tissue- facing side 160 of the sealing member 132 and the second, tissue-facing side 166 of the absorbent layer 162 may be coupled to the first side 152 of the manifold member 130.
  • the absorbent layer 162 functions primarily to store or maintain fluids.
  • the absorbent layer 162 may be formed from super-absorbent polymers (SAP) or other materials suited for retaining fluids within the re-epithelialization dressing 102.
  • SAP super-absorbent polymers
  • the material and thickness of the material forming the absorbent layer 162 may be selected based on the desired quantity of fluid to be retained.
  • the absorbent layer 162 may be formed from one or more constituent layers.
  • the tissue site 104 may be treated with the wound treatment system 100 by deploying the re-epithelialization dressing 102.
  • the re-epithelialization dressing 102 is placed adjacent to the wound 106 and a portion of the patient's intact epidermis 108.
  • the reduced-pressure connector 1 14 is fluidly coupled to the re- epithelialization dressing 102 to provide reduced pressure and, if not already deployed, the sealing member 132 is deployed over other portions of the re-epithelialization dressing 102.
  • the second, tissue-facing side 138 of the moist tissue-interface layer 126 is thus disposed adjacent to the wound 106 and a portion of the intact epidermis 108 as shown in FIGURE 1.
  • the second, tissue-facing side 138 presents a moist, smooth surface to the wound 106 and the wound edges 1 12.
  • the reduced-pressure delivery conduit 116 is fluidly coupled to the reduced-pressure connector 1 14 and to the reduced-pressure source 120.
  • the reduced-pressure source 120 is activated and reduced pressure is thereby supplied to the re- epithelialization dressing 102.
  • the reduced pressure may help to hold the re-epithelialization dressing 102 in situ, may help avoid any fluid leaks from the re-epithelialization dressing 102, may help avoid infection, and may help to manage fluids.
  • the reduced pressure provided to the re-epithelialization dressing 102 is in the range of -10 to -100 mm Hg and more typically in the range of -25 to -75 mm Hg.
  • the reduced pressure is adequate to cause a flow of fluid, but is not typically high enough to cause substantial micro-strain at the tissue site 104.
  • the reduced pressure may be between the range of -10 mm Hg and -200 mm Hg.
  • the reduced pressure may be in the range of -100 to -200 mm Hg for an initial time period and then be in the range of -25 to -100 mm Hg for a second time period. Other variations are possible as desired.
  • the first plurality of apertures 140 may go immediately or over time with saturation from an open position (FIGURE 2) to a restricted position or state (FIGURE 3). In the restricted state, the first plurality of apertures 140 may allow liquids to pass, but prevent or restrict gases (and gaseous pressure) from being transmitted. The re-epithelialization dressing 102 may thereby exert a force on the tissue site 104 without communicating gaseous pressure. If included, the support layer 128 may hold the first end 148 of the first plurality of apertures 140 substantially open or with a constant diameter.
  • the reduced pressure delivered to the re-epithelialization dressing 102 helps to remove excess fluids from the tissue site 104 and helps to remove fluids from the moist tissue- interface layer 126 when the moist tissue-interface layer 126 becomes substantially saturated.
  • the fluid balance, or equilibrium, of the moist tissue-interface layer 126 also helps manage fluid in that the moist tissue-interface layer 126 provides fluid when the tissue site 104 is dry or helps absorb fluids when the tissue site 104 is wet.
  • the fluid removal by the moist tissue- interface layer 126 may be slowly accomplished to allow some exudate (but not pooling of exudate) to remain at the tissue site 104 to facilitate the healing process.
  • the exudate may help by allowing signaling (e.g., from growth factors) to activate keratinocytes as previously mentioned.
  • the moist tissue- interface layer 126 also provides a relatively smooth surface against the tissue site 104 that may facilitate (or at least not inhibit) cell migration. In addition to providing a relatively smooth moist surface, the moist tissue-interface layer 126 may be left for extended periods of time against the tissue site 104 without granulation in-growth, infection, or the need for frequent dressing changes.

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Materials For Medical Uses (AREA)
PCT/US2010/045735 2009-08-27 2010-08-17 Re-epithelialization wound dressings and systems Ceased WO2011028407A1 (en)

Priority Applications (5)

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JP2012526840A JP5911066B2 (ja) 2009-08-27 2010-08-17 上皮再形成式創傷用医薬材料およびシステム
AU2010289910A AU2010289910C1 (en) 2009-08-27 2010-08-17 Re-epithelialization wound dressings and systems
CN201080037769.0A CN102481209B (zh) 2009-08-27 2010-08-17 上皮再形成创伤敷料和系统
EP10747361.3A EP2470135B1 (en) 2009-08-27 2010-08-17 Re-epithelialization wound dressings and systems
CA2771522A CA2771522C (en) 2009-08-27 2010-08-17 Re-epithelialization wound dressings and systems

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US23748609P 2009-08-27 2009-08-27
US61/237,486 2009-08-27
US12/857,100 2010-08-16
US12/857,100 US8690844B2 (en) 2009-08-27 2010-08-16 Re-epithelialization wound dressings and systems

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EP (1) EP2470135B1 (enExample)
JP (1) JP5911066B2 (enExample)
CN (1) CN102481209B (enExample)
AU (1) AU2010289910C1 (enExample)
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013066426A3 (en) * 2011-06-24 2013-09-06 Kci Licensing, Inc. Reduced-pressure dressings employing tissue-fixation elements
EP2470135B1 (en) 2009-08-27 2016-10-12 KCI Licensing, Inc. Re-epithelialization wound dressings and systems
EP2879636B1 (en) 2012-08-01 2017-03-22 Smith & Nephew PLC Wound dressing
US11357903B2 (en) 2009-02-13 2022-06-14 Smith & Nephew Plc Wound packing
US11484443B2 (en) 2010-02-26 2022-11-01 Smith & Nephew, Inc. Systems and methods for using negative pressure wound therapy to manage open abdominal wounds
US11554051B2 (en) 2017-06-30 2023-01-17 T.J. Smith And Nephew, Limited Negative pressure wound therapy apparatus
US11771796B2 (en) 2013-03-15 2023-10-03 Smith & Nephew Plc Wound dressing and method of treatment

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7559324B2 (en) 2000-06-21 2009-07-14 Fisher & Paykel Healthcare Limited Conduit with heated wick
AU2003244171B2 (en) 2002-09-09 2007-11-15 Fisher & Paykel Healthcare Limited Limb for Breathing Circuit
GB0224986D0 (en) 2002-10-28 2002-12-04 Smith & Nephew Apparatus
GB0325129D0 (en) 2003-10-28 2003-12-03 Smith & Nephew Apparatus in situ
US8062272B2 (en) * 2004-05-21 2011-11-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US7909805B2 (en) 2004-04-05 2011-03-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US7776028B2 (en) 2004-04-05 2010-08-17 Bluesky Medical Group Incorporated Adjustable overlay reduced pressure wound treatment system
US10058642B2 (en) 2004-04-05 2018-08-28 Bluesky Medical Group Incorporated Reduced pressure treatment system
US7708724B2 (en) * 2004-04-05 2010-05-04 Blue Sky Medical Group Incorporated Reduced pressure wound cupping treatment system
CA2949821C (en) 2005-09-06 2021-05-18 Smith & Nephew, Inc. Self contained wound dressing with micropump
US7779625B2 (en) * 2006-05-11 2010-08-24 Kalypto Medical, Inc. Device and method for wound therapy
CN101883546B (zh) * 2007-11-21 2017-05-10 史密夫及内修公开有限公司 伤口包敷物
EP3354243A1 (en) 2007-11-21 2018-08-01 Smith & Nephew PLC Wound dressing
JP2011521708A (ja) * 2008-05-27 2011-07-28 カリプト メディカル インコーポレーション 陰圧式外傷治療具
WO2010121186A1 (en) * 2009-04-17 2010-10-21 Kalypto Medical, Inc. Negative pressure wound therapy device
US9061095B2 (en) 2010-04-27 2015-06-23 Smith & Nephew Plc Wound dressing and method of use
GB201108229D0 (en) * 2011-05-17 2011-06-29 Smith & Nephew Tissue healing
US9058634B2 (en) 2011-05-24 2015-06-16 Kalypto Medical, Inc. Method for providing a negative pressure wound therapy pump device
US8945074B2 (en) 2011-05-24 2015-02-03 Kalypto Medical, Inc. Device with controller and pump modules for providing negative pressure for wound therapy
US9067003B2 (en) 2011-05-26 2015-06-30 Kalypto Medical, Inc. Method for providing negative pressure to a negative pressure wound therapy bandage
BR112014000775A2 (pt) 2011-07-14 2017-02-14 Smith & Nephew curativo de ferimento e método de tratamento
MX2014011030A (es) 2012-03-12 2015-03-20 Smith & Nephew Aparato y metodos de presion reducida.
CA2874509C (en) 2012-05-23 2021-01-26 Smith & Nephew Plc Apparatuses and methods for negative pressure wound therapy
EP4112020B1 (en) 2012-08-01 2025-12-10 Smith & Nephew plc Wound dressing and method of treatment
AU2014228670B2 (en) 2013-03-14 2018-07-19 Kci Licensing, Inc. Absorbent dressing and method of making the same
FR3015230B1 (fr) * 2013-12-19 2020-08-07 Commissariat Energie Atomique Article pour absorber un liquide physiologique, notamment pansement
AU2015255726B2 (en) 2014-05-09 2020-03-05 Solventum Intellectual Properties Company Disruptive dressing for use with negative pressure and fluid instillation
EP3797744A1 (en) 2014-05-09 2021-03-31 3M Innovative Properties Company Dressing with contracting layer for linear tissue sites
EP3527180B1 (en) 2014-05-09 2021-01-06 3M Innovative Properties Company Debriding dressing for use with negative pressure and fluid instillation
US10898217B2 (en) 2014-05-09 2021-01-26 Kci Licensing, Inc. Dressing providing apertures with multiple orifice sizes for negative-pressure therapy
US11007086B2 (en) * 2014-12-30 2021-05-18 3M Innovative Properties Company Wound dressing with multiple adhesive layers
DK3288508T3 (da) 2015-04-27 2020-03-09 Smith & Nephew Anordninger med reduceret tryk
CN105536038B (zh) * 2015-12-25 2019-11-19 厦门百美特生物材料科技有限公司 泡沫基敷料及其制备方法
EP3426206B1 (en) 2016-03-07 2023-05-10 Smith & Nephew plc Wound treatment apparatuses and methods with negative pressure source integrated into wound dressing
WO2017186771A1 (en) 2016-04-26 2017-11-02 Smith & Nephew Plc Wound dressings and methods of use with integrated negative pressure source having a fluid ingress inhibition component
KR20190008199A (ko) 2016-03-30 2019-01-23 시노보 게엠베하 상처에서 미생물 감염의 검출 방법
WO2017191149A1 (en) 2016-05-03 2017-11-09 Smith & Nephew Plc Optimizing power transfer to negative pressure sources in negative pressure therapy systems
WO2017191158A1 (en) 2016-05-03 2017-11-09 Smith & Nephew Plc Systems and methods for driving negative pressure sources in negative pressure therapy systems
WO2017191154A1 (en) 2016-05-03 2017-11-09 Smith & Nephew Plc Negative pressure wound therapy device activation and control
CA3034789A1 (en) 2016-08-25 2018-03-01 Smith & Nephew Plc Absorbent negative pressure wound therapy dressing
AU2017336305B2 (en) 2016-09-30 2023-01-19 Smith & Nephew Plc Negative pressure wound treatment apparatuses and methods with integrated electronics
JP7055795B2 (ja) 2016-09-30 2022-04-18 スミス アンド ネフュー ピーエルシー 一体化された電子機器を備えた陰圧創傷治療装置及び方法
WO2019053101A1 (en) 2017-09-13 2019-03-21 Smith & Nephew Plc APPARATUS AND METHODS FOR NEGATIVE PRESSURE WOUND TREATMENT WITH INTEGRATED ELECTRONICS
GB2555584B (en) 2016-10-28 2020-05-27 Smith & Nephew Multi-layered wound dressing and method of manufacture
CA3046416A1 (en) 2016-12-12 2018-06-21 Smith & Nephew Plc Pressure wound therapy status indication via external device
CN110582257B (zh) 2017-03-08 2022-03-15 史密夫及内修公开有限公司 存在故障条件时的负压伤口治疗装置控制
CA3062507A1 (en) 2017-05-09 2018-11-15 Smith & Nephew Plc Redundant controls for negative pressure wound therapy systems
CA3060588A1 (en) 2017-06-07 2018-12-13 Kci Licensing, Inc. Composite dressings for improved granulation and reduced maceration with negative-pressure treatment
EP3634334B1 (en) 2017-06-07 2023-05-24 3M Innovative Properties Company Multi-layer wound filler for extended wear time
BR112019025025A2 (pt) * 2017-06-07 2020-06-16 Kci Licensing, Inc Penso para tratar um sítio de tecido com pressão negativa, sistema para tratar tecido com pressão negativa, método para tratar um ferimento com pressão negativa, uso dos mesmos, e sistemas, aparelhos e metodos
AU2018280130A1 (en) 2017-06-07 2019-12-19 3M Innovative Properties Company Composite dressings for improved granulation reduced maceration with negative-pressure treatment
WO2018226650A1 (en) 2017-06-07 2018-12-13 Kci Licensing, Inc. Systems, apparatuses, and methods for negative-pressure treatment with reduced tissue in-growth
US11471584B2 (en) 2017-06-07 2022-10-18 Kci Licensing, Inc. Composite dressings for improved granulation and reduced maceration with negative-pressure treatment
CA3060484A1 (en) * 2017-06-07 2018-12-13 Kci Licensing, Inc. Customizable composite dressings for improved granulation and reduced maceration with negative-pressure treatment
US11207217B2 (en) 2017-06-07 2021-12-28 Kci Licensing, Inc. Methods for manufacturing and assembling dual material tissue interface for negative-pressure therapy
CA3066093A1 (en) 2017-06-07 2018-12-13 Kci Licensing, Inc. Composite dressings for improved granulation and reduced maceration with negative-pressure treatment
WO2018226687A1 (en) 2017-06-07 2018-12-13 Kci Licensing, Inc. Methods for manufacturing and assembling dual material tissue interface for negative-pressure therapy
WO2018226630A1 (en) 2017-06-07 2018-12-13 Kci Licensing, Inc. Assembly features and methods for a peel-and-place dressing for use with negative-pressure treatment
GB201718070D0 (en) 2017-11-01 2017-12-13 Smith & Nephew Negative pressure wound treatment apparatuses and methods with integrated electronics
GB201718054D0 (en) 2017-11-01 2017-12-13 Smith & Nephew Sterilization of integrated negative pressure wound treatment apparatuses and sterilization methods
EP3703632B1 (en) 2017-11-01 2024-04-03 Smith & Nephew plc Negative pressure wound treatment apparatuses and methods with integrated electronics
GB201718072D0 (en) 2017-11-01 2017-12-13 Smith & Nephew Negative pressure wound treatment apparatuses and methods with integrated electronics
EP3735211B1 (en) * 2018-01-04 2024-03-13 Solventum Intellectual Properties Company Peel and place dressing for thick exudate and instillation
US20220111138A1 (en) * 2018-09-12 2022-04-14 Kci Licensing, Inc. Systems, apparatuses, and methods for negative-pressure treatment with reduced tissue in-growth
USD898925S1 (en) 2018-09-13 2020-10-13 Smith & Nephew Plc Medical dressing
CN112912042A (zh) * 2018-09-14 2021-06-04 凯希特许有限公司 差异塌缩伤口敷料
EP3876885B1 (en) * 2018-11-08 2023-11-29 3M Innovative Properties Company Wound dressing with semi-rigid support to increase disruption using perforated dressing and negative pressure wound therapy
GB201903774D0 (en) 2019-03-20 2019-05-01 Smith & Nephew Negative pressure wound treatment apparatuses and methods with integrated electronics
GB201907716D0 (en) 2019-05-31 2019-07-17 Smith & Nephew Systems and methods for extending operational time of negative pressure wound treatment apparatuses
EP4069170B1 (en) * 2019-12-04 2024-07-03 KCI Manufacturing Unlimited Company Tissue interface for negative pressure and instillation therapy
WO2021111412A1 (en) 2019-12-05 2021-06-10 Kci Licensing, Inc. Multi-layer negative pressure incisional wound therapy dressing
CA3165269A1 (en) 2019-12-23 2021-07-01 Convatec Limited Point of care devices for detecting infection status of a wound
US20230263666A1 (en) * 2020-07-09 2023-08-24 Kci Licensing, Inc. Tissue interface for tissue debridement

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001085248A1 (en) * 2000-05-09 2001-11-15 Kci Licensing, Inc. Abdominal wound dressing
WO2004037334A1 (en) * 2002-10-28 2004-05-06 Smith & Nephew Plc Apparatus for aspirating, irrigating and cleansing wounds
US20050085795A1 (en) * 2002-02-28 2005-04-21 Lockwood Jeffrey S. External catheter access to vacuum bandage
WO2008141228A1 (en) * 2007-05-10 2008-11-20 Kci Licensing Inc. Reduced pressure wound dressing having a wound contact surface with columnar protrusions

Family Cites Families (188)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1355846A (en) 1920-02-06 1920-10-19 David A Rannells Medical appliance
US2547758A (en) 1949-01-05 1951-04-03 Wilmer B Keeling Instrument for treating the male urethra
US2632443A (en) 1949-04-18 1953-03-24 Eleanor P Lesher Surgical dressing
GB692578A (en) 1949-09-13 1953-06-10 Minnesota Mining & Mfg Improvements in or relating to drape sheets for surgical use
US2682873A (en) 1952-07-30 1954-07-06 Johnson & Johnson General purpose protective dressing
NL189176B (nl) 1956-07-13 1900-01-01 Hisamitsu Pharmaceutical Co Pleister op basis van een synthetische rubber.
US2969057A (en) 1957-11-04 1961-01-24 Brady Co W H Nematodic swab
US3066672A (en) 1960-09-27 1962-12-04 Jr William H Crosby Method and apparatus for serial sampling of intestinal juice
US3367332A (en) 1965-08-27 1968-02-06 Gen Electric Product and process for establishing a sterile area of skin
US3520300A (en) 1967-03-15 1970-07-14 Amp Inc Surgical sponge and suction device
US3568675A (en) 1968-08-30 1971-03-09 Clyde B Harvey Fistula and penetrating wound dressing
US3682180A (en) 1970-06-08 1972-08-08 Coilform Co Inc Drain clip for surgical drain
BE789293Q (fr) 1970-12-07 1973-01-15 Parke Davis & Co Pansement medico-chirugical pour brulures et lesions analogues
US3826254A (en) 1973-02-26 1974-07-30 Verco Ind Needle or catheter retaining appliance
DE2527706A1 (de) 1975-06-21 1976-12-30 Hanfried Dr Med Weigand Einrichtung zum einleiten von kontrastmittel in einen kuenstlichen darmausgang
DE2640413C3 (de) 1976-09-08 1980-03-27 Richard Wolf Gmbh, 7134 Knittlingen Katheter-Überwachungsgerät
NL7710909A (nl) 1976-10-08 1978-04-11 Smith & Nephew Samengestelde hechtstrook.
GB1562244A (en) 1976-11-11 1980-03-05 Lock P M Wound dressing materials
US4080970A (en) 1976-11-17 1978-03-28 Miller Thomas J Post-operative combination dressing and internal drain tube with external shield and tube connector
US4139004A (en) 1977-02-17 1979-02-13 Gonzalez Jr Harry Bandage apparatus for treating burns
US4184510A (en) 1977-03-15 1980-01-22 Fibra-Sonics, Inc. Valued device for controlling vacuum in surgery
US4165748A (en) 1977-11-07 1979-08-28 Johnson Melissa C Catheter tube holder
US4256109A (en) 1978-07-10 1981-03-17 Nichols Robert L Shut off valve for medical suction apparatus
SE414994B (sv) 1978-11-28 1980-09-01 Landstingens Inkopscentral Venkateterforband
US4382441A (en) 1978-12-06 1983-05-10 Svedman Paul Device for treating tissues, for example skin
US4266545A (en) 1979-04-06 1981-05-12 Moss James P Portable suction device for collecting fluids from a closed wound
US4284079A (en) 1979-06-28 1981-08-18 Adair Edwin Lloyd Method for applying a male incontinence device
US4261363A (en) 1979-11-09 1981-04-14 C. R. Bard, Inc. Retention clips for body fluid drains
US4569348A (en) 1980-02-22 1986-02-11 Velcro Usa Inc. Catheter tube holder strap
US4480638A (en) 1980-03-11 1984-11-06 Eduard Schmid Cushion for holding an element of grafted skin
US4297995A (en) 1980-06-03 1981-11-03 Key Pharmaceuticals, Inc. Bandage containing attachment post
US4333468A (en) 1980-08-18 1982-06-08 Geist Robert W Mesentery tube holder apparatus
US4465485A (en) 1981-03-06 1984-08-14 Becton, Dickinson And Company Suction canister with unitary shut-off valve and filter features
US4392853A (en) 1981-03-16 1983-07-12 Rudolph Muto Sterile assembly for protecting and fastening an indwelling device
US4373519A (en) 1981-06-26 1983-02-15 Minnesota Mining And Manufacturing Company Composite wound dressing
US4392858A (en) 1981-07-16 1983-07-12 Sherwood Medical Company Wound drainage device
US4419097A (en) 1981-07-31 1983-12-06 Rexar Industries, Inc. Attachment for catheter tube
AU550575B2 (en) 1981-08-07 1986-03-27 Richard Christian Wright Wound drainage device
SE429197B (sv) 1981-10-14 1983-08-22 Frese Nielsen Anordning for behandling av sar
DE3146266A1 (de) 1981-11-21 1983-06-01 B. Braun Melsungen Ag, 3508 Melsungen Kombinierte vorrichtung fuer eine medizinische saugdrainage
US4551139A (en) 1982-02-08 1985-11-05 Marion Laboratories, Inc. Method and apparatus for burn wound treatment
US4417574A (en) 1982-05-03 1983-11-29 Sherwood Medical Company Liquid drain for patient breathing apparatus
US4475909A (en) 1982-05-06 1984-10-09 Eisenberg Melvin I Male urinary device and method for applying the device
DE3361779D1 (en) 1982-07-06 1986-02-20 Dow Corning Medical-surgical dressing and a process for the production thereof
NZ206837A (en) 1983-01-27 1986-08-08 Johnson & Johnson Prod Inc Thin film adhesive dressing:backing material in three sections
US4548202A (en) 1983-06-20 1985-10-22 Ethicon, Inc. Mesh tissue fasteners
US4540412A (en) 1983-07-14 1985-09-10 The Kendall Company Device for moist heat therapy
US4543100A (en) 1983-11-01 1985-09-24 Brodsky Stuart A Catheter and drain tube retainer
US4525374A (en) 1984-02-27 1985-06-25 Manresa, Inc. Treating hydrophobic filters to render them hydrophilic
CA1286177C (en) 1984-05-03 1991-07-16 Smith And Nephew Associated Companies Plc Adhesive wound dressing
US4897081A (en) 1984-05-25 1990-01-30 Thermedics Inc. Percutaneous access device
US5215522A (en) 1984-07-23 1993-06-01 Ballard Medical Products Single use medical aspirating device and method
GB8419745D0 (en) 1984-08-02 1984-09-05 Smith & Nephew Ass Wound dressing
US4872450A (en) 1984-08-17 1989-10-10 Austad Eric D Wound dressing and method of forming same
US4655754A (en) 1984-11-09 1987-04-07 Stryker Corporation Vacuum wound drainage system and lipids baffle therefor
US4826494A (en) 1984-11-09 1989-05-02 Stryker Corporation Vacuum wound drainage system
US4605399A (en) 1984-12-04 1986-08-12 Complex, Inc. Transdermal infusion device
US5037397A (en) 1985-05-03 1991-08-06 Medical Distributors, Inc. Universal clamp
US4640688A (en) 1985-08-23 1987-02-03 Mentor Corporation Urine collection catheter
US4710165A (en) 1985-09-16 1987-12-01 Mcneil Charles B Wearable, variable rate suction/collection device
US4758220A (en) 1985-09-26 1988-07-19 Alcon Laboratories, Inc. Surgical cassette proximity sensing and latching apparatus
US4733659A (en) 1986-01-17 1988-03-29 Seton Company Foam bandage
EP0256060A1 (en) 1986-01-31 1988-02-24 OSMOND, Roger L. W. Suction system for wound and gastro-intestinal drainage
US4838883A (en) 1986-03-07 1989-06-13 Nissho Corporation Urine-collecting device
JPS62281965A (ja) 1986-05-29 1987-12-07 テルモ株式会社 カテ−テルおよびカテ−テル用固定部材
GB8621884D0 (en) 1986-09-11 1986-10-15 Bard Ltd Catheter applicator
GB2195255B (en) 1986-09-30 1991-05-01 Vacutec Uk Limited Apparatus for vacuum treatment of an epidermal surface
US4743232A (en) 1986-10-06 1988-05-10 The Clinipad Corporation Package assembly for plastic film bandage
DE3634569A1 (de) 1986-10-10 1988-04-21 Sachse Hans E Kondomkatheter, ein harnroehrenkatheter zur verhinderung von aufsteigenden infektionen
JPS63135179A (ja) 1986-11-26 1988-06-07 立花　俊郎 薬物の経皮投与具
GB8628564D0 (en) 1986-11-28 1987-01-07 Smiths Industries Plc Anti-foaming agent suction apparatus
GB8706116D0 (en) 1987-03-14 1987-04-15 Smith & Nephew Ass Adhesive dressings
US4787888A (en) 1987-06-01 1988-11-29 University Of Connecticut Disposable piezoelectric polymer bandage for percutaneous delivery of drugs and method for such percutaneous delivery (a)
US4863449A (en) 1987-07-06 1989-09-05 Hollister Incorporated Adhesive-lined elastic condom cathether
US5176663A (en) * 1987-12-02 1993-01-05 Pal Svedman Dressing having pad with compressibility limiting elements
US5018515A (en) * 1987-12-14 1991-05-28 The Kendall Company See through absorbent dressing
US4906240A (en) 1988-02-01 1990-03-06 Matrix Medica, Inc. Adhesive-faced porous absorbent sheet and method of making same
US4985019A (en) 1988-03-11 1991-01-15 Michelson Gary K X-ray marker
GB8812803D0 (en) 1988-05-28 1988-06-29 Smiths Industries Plc Medico-surgical containers
US4919654A (en) 1988-08-03 1990-04-24 Kalt Medical Corporation IV clamp with membrane
US5000741A (en) 1988-08-22 1991-03-19 Kalt Medical Corporation Transparent tracheostomy tube dressing
EP0379416B1 (fr) 1989-01-16 1995-03-08 Roussel-Uclaf Dérivés d'azabicycloheptène et leurs sels, leur procédé de préparation, leur application comme médicaments et les compositions les renfermant
GB8906100D0 (en) 1989-03-16 1989-04-26 Smith & Nephew Laminates
US5527293A (en) 1989-04-03 1996-06-18 Kinetic Concepts, Inc. Fastening system and method
US5261893A (en) 1989-04-03 1993-11-16 Zamierowski David S Fastening system and method
US5100396A (en) 1989-04-03 1992-03-31 Zamierowski David S Fluidic connection system and method
US4969880A (en) 1989-04-03 1990-11-13 Zamierowski David S Wound dressing and treatment method
JP2719671B2 (ja) * 1989-07-11 1998-02-25 日本ゼオン株式会社 創傷被覆材
US5358494A (en) 1989-07-11 1994-10-25 Svedman Paul Irrigation dressing
US5232453A (en) 1989-07-14 1993-08-03 E. R. Squibb & Sons, Inc. Catheter holder
GB2235877A (en) 1989-09-18 1991-03-20 Antonio Talluri Closed wound suction apparatus
US5106629A (en) * 1989-10-20 1992-04-21 Ndm Acquisition Corp. Transparent hydrogel wound dressing
US5134994A (en) 1990-02-12 1992-08-04 Say Sam L Field aspirator in a soft pack with externally mounted container
US5092858A (en) 1990-03-20 1992-03-03 Becton, Dickinson And Company Liquid gelling agent distributor device
JP2941918B2 (ja) 1990-09-19 1999-08-30 テルモ株式会社 秤量装置
US5160315A (en) * 1991-04-05 1992-11-03 Minnesota Mining And Manufacturing Company Combined adhesive strip and transparent dressing delivery system
US5149331A (en) 1991-05-03 1992-09-22 Ariel Ferdman Method and device for wound closure
US5278100A (en) 1991-11-08 1994-01-11 Micron Technology, Inc. Chemical vapor deposition technique for depositing titanium silicide on semiconductor wafers
US5645081A (en) 1991-11-14 1997-07-08 Wake Forest University Method of treating tissue damage and apparatus for same
US5636643A (en) 1991-11-14 1997-06-10 Wake Forest University Wound treatment employing reduced pressure
US5279550A (en) 1991-12-19 1994-01-18 Gish Biomedical, Inc. Orthopedic autotransfusion system
US5167613A (en) 1992-03-23 1992-12-01 The Kendall Company Composite vented wound dressing
FR2690617B1 (fr) 1992-04-29 1994-06-24 Cbh Textile Pansement adhesif transparent.
DE59309311D1 (de) * 1992-10-02 1999-02-25 Beiersdorf Ag Hydrophile polyurethangelschäume, insbesondere zur behandlung von tiefen wunden, wundverbände auf basis hydrophiler polyurethangelschäume und verfahren zur herstellung
DE4306478A1 (de) 1993-03-02 1994-09-08 Wolfgang Dr Wagner Drainagevorrichtung, insbesondere Pleuradrainagevorrichtung, und Drainageverfahren
US5342376A (en) 1993-05-03 1994-08-30 Dermagraphics, Inc. Inserting device for a barbed tissue connector
US6241747B1 (en) 1993-05-03 2001-06-05 Quill Medical, Inc. Barbed Bodily tissue connector
US5423737A (en) * 1993-05-27 1995-06-13 New Dimensions In Medicine, Inc. Transparent hydrogel wound dressing with release tab
US5344415A (en) 1993-06-15 1994-09-06 Deroyal Industries, Inc. Sterile system for dressing vascular access site
US5437651A (en) * 1993-09-01 1995-08-01 Research Medical, Inc. Medical suction apparatus
US5356372A (en) * 1993-12-01 1994-10-18 Ludlow Corporation Occlusive pressure-reducing wound dressing
US5549584A (en) 1994-02-14 1996-08-27 The Kendall Company Apparatus for removing fluid from a wound
US5556375A (en) 1994-06-16 1996-09-17 Hercules Incorporated Wound dressing having a fenestrated base layer
US5607388A (en) 1994-06-16 1997-03-04 Hercules Incorporated Multi-purpose wound dressing
US5664270A (en) 1994-07-19 1997-09-09 Kinetic Concepts, Inc. Patient interface system
ATE226838T1 (de) 1994-08-22 2002-11-15 Kinetic Concepts Inc Kanister für wunddrainagen
DE29504378U1 (de) 1995-03-15 1995-09-14 MTG Medizinisch, technische Gerätebau GmbH, 66299 Friedrichsthal Elektronisch geregelte Niedervakuumpumpe für die Thorax- und Wunddrainage
US8801681B2 (en) * 1995-09-05 2014-08-12 Argentum Medical, Llc Medical device
GB9523253D0 (en) 1995-11-14 1996-01-17 Mediscus Prod Ltd Portable wound treatment apparatus
US6135116A (en) 1997-07-28 2000-10-24 Kci Licensing, Inc. Therapeutic method for treating ulcers
US6420622B1 (en) * 1997-08-01 2002-07-16 3M Innovative Properties Company Medical article having fluid control film
AU755496B2 (en) 1997-09-12 2002-12-12 Kci Licensing, Inc. Surgical drape and suction head for wound treatment
GB9719520D0 (en) 1997-09-12 1997-11-19 Kci Medical Ltd Surgical drape and suction heads for wound treatment
US6071267A (en) 1998-02-06 2000-06-06 Kinetic Concepts, Inc. Medical patient fluid management interface system and method
US6488643B1 (en) 1998-10-08 2002-12-03 Kci Licensing, Inc. Wound healing foot wrap
US6287316B1 (en) 1999-03-26 2001-09-11 Ethicon, Inc. Knitted surgical mesh
US7947033B2 (en) * 1999-04-06 2011-05-24 Kci Licensing Inc. Systems and methods for detection of wound fluid blood and application of phototherapy in conjunction with reduced pressure wound treatment system
US6856821B2 (en) 2000-05-26 2005-02-15 Kci Licensing, Inc. System for combined transcutaneous blood gas monitoring and vacuum assisted wound closure
US7799004B2 (en) 2001-03-05 2010-09-21 Kci Licensing, Inc. Negative pressure wound treatment apparatus and infection identification system and method
US6991643B2 (en) 2000-12-20 2006-01-31 Usgi Medical Inc. Multi-barbed device for retaining tissue in apposition and methods of use
US6566575B1 (en) * 2000-02-15 2003-05-20 3M Innovative Properties Company Patterned absorbent article for wound dressing
CA2400895C (en) 2000-02-24 2011-09-13 Venetec International, Inc. Universal catheter anchoring system
GB0008328D0 (en) * 2000-04-06 2000-05-24 Adv Med Solutions Ltd Pressure sensitive adhesive compositions
CA2409907A1 (en) * 2000-05-22 2001-11-29 Arthur C. Coffey Combination sis and vacuum bandage and method
US6903243B1 (en) * 2000-09-08 2005-06-07 3M Innovative Properties Company Multi-layer absorbent wound dressing
US6685681B2 (en) * 2000-11-29 2004-02-03 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US6596402B2 (en) * 2000-12-29 2003-07-22 Kimberly-Clark Worldwide, Inc. Absorbent, lubricious coating and articles coated therewith
US7700819B2 (en) * 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
US7070584B2 (en) * 2001-02-20 2006-07-04 Kci Licensing, Inc. Biocompatible wound dressing
US7763769B2 (en) * 2001-02-16 2010-07-27 Kci Licensing, Inc. Biocompatible wound dressing
US6540705B2 (en) 2001-02-22 2003-04-01 Core Products International, Inc. Ankle brace providing upper and lower ankle adjustment
WO2002092783A2 (en) 2001-05-15 2002-11-21 Children's Medical Center Corporation Methods and apparatus for application of micro-mechanical forces to tissues
US7004915B2 (en) * 2001-08-24 2006-02-28 Kci Licensing, Inc. Negative pressure assisted tissue treatment system
GB0127822D0 (en) * 2001-11-20 2002-01-09 Maelor Pharmaceuticals Ltd Medical dressings
EP1461113A4 (en) * 2001-12-26 2009-05-06 Hill Rom Services Inc ASSOCIATION SET FOR WOUND VACUUM THERAPY
US7005143B2 (en) * 2002-04-12 2006-02-28 3M Innovative Properties Company Gel materials, medical articles, and methods
EP2545946B1 (en) * 2002-08-21 2016-11-16 KCI Medical Resources Wound packing for preventing wound closure
US7846141B2 (en) 2002-09-03 2010-12-07 Bluesky Medical Group Incorporated Reduced pressure treatment system
US7520872B2 (en) * 2002-09-13 2009-04-21 Neogen Technologies, Inc. Closed wound drainage system
US7976519B2 (en) 2002-12-31 2011-07-12 Kci Licensing, Inc. Externally-applied patient interface system and method
JP4448093B2 (ja) * 2002-12-31 2010-04-07 ベーエスエヌ・メディカル・ゲーエムベーハー 創傷包帯
US20050037194A1 (en) * 2003-08-15 2005-02-17 Kimberly-Clark Worldwide, Inc. Thermoplastic polymers with thermally reversible and non-reversible linkages, and articles using same
GB0325120D0 (en) 2003-10-28 2003-12-03 Smith & Nephew Apparatus with actives
GB0325126D0 (en) 2003-10-28 2003-12-03 Smith & Nephew Apparatus with heat
US7790945B1 (en) * 2004-04-05 2010-09-07 Kci Licensing, Inc. Wound dressing with absorption and suction capabilities
US7909805B2 (en) 2004-04-05 2011-03-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US7884258B2 (en) * 2004-04-13 2011-02-08 Boehringer Technologies, L.P. Wound contact device
US8529548B2 (en) 2004-04-27 2013-09-10 Smith & Nephew Plc Wound treatment apparatus and method
GB2415382A (en) 2004-06-21 2005-12-28 Johnson & Johnson Medical Ltd Wound dressings for vacuum therapy
DE202004017052U1 (de) 2004-11-02 2005-06-09 Riesinger, Birgit Vorrichtung zur Wundbehandlung unter Einsatz von Unterdruck
ES2901826T3 (es) * 2004-11-05 2022-03-23 Convatec Technologies Inc Módulo para el cuidado de heridas al vacío
DE202004018245U1 (de) 2004-11-24 2005-07-07 Riesinger, Birgit Drainagevorrichtung zur Wundbehandlung unter Einsatz von Unterdruck
US7857806B2 (en) * 2005-07-14 2010-12-28 Boehringer Technologies, L.P. Pump system for negative pressure wound therapy
MX2008002882A (es) 2005-09-07 2008-03-27 Tyco Healthcare Aposito de herida con deposito de vacio.
CA2620401C (en) * 2005-09-07 2016-05-24 Tyco Healthcare Group Lp Self contained wound dressing apparatus
DE202006016821U1 (de) 2005-11-02 2007-03-29 Riesinger, Birgit Absorbierender Körper zur Anbringung an menschliche oder tierische Körperoberflächen
EP3533478B1 (en) * 2006-02-06 2021-08-11 3M Innovative Properties Company Systems for improved connection to wound dressings in conjunction with reduced pressure wound treatment
US8002313B2 (en) * 2006-04-25 2011-08-23 Kci Licensing, Inc. Inline swivel connection for multi-lumen tubing
US8476326B2 (en) * 2006-09-22 2013-07-02 Dow Global Technologies Llc Fibrillated polyolefin foam
DE102006047041A1 (de) 2006-10-02 2008-04-10 Birgit Riesinger Flächenhafter Absorptionskörper
US8287507B2 (en) * 2006-10-13 2012-10-16 Kci Licensing, Inc. Reduced pressure indicator for a reduced pressure source
US20080215020A1 (en) * 2007-01-22 2008-09-04 Reeves William H Apparatuses and methods for healing wounds
US20090043268A1 (en) * 2007-08-06 2009-02-12 Eddy Patrick E Wound treatment system and suction regulator for use therewith
RU2010135033A (ru) * 2008-03-05 2012-04-10 КейСиАй Лайсензинг Инк. (US) Повязка и способ приложения пониженного давления к участку ткани и сбора и хранения текучей среды от участка ткани
US8021347B2 (en) 2008-07-21 2011-09-20 Tyco Healthcare Group Lp Thin film wound dressing
MX2010011909A (es) * 2008-05-02 2010-11-26 Kci Licensing Inc Sistema de tratamiento de presion reducida manualmente activado que tiene capacidades de presion regulada.
US8007481B2 (en) 2008-07-17 2011-08-30 Tyco Healthcare Group Lp Subatmospheric pressure mechanism for wound therapy system
EP2279018B8 (en) * 2008-05-30 2017-04-19 KCI Licensing, Inc. Reduced-pressure, compression systems and apparatuses for use on a curved body part
JP2011524191A (ja) * 2008-06-04 2011-09-01 ケーシーアイ ライセンシング インコーポレイテッド 多方向性フィルタを有する減圧、液体収集キャニスタ
US8216198B2 (en) 2009-01-09 2012-07-10 Tyco Healthcare Group Lp Canister for receiving wound exudate in a negative pressure therapy system
US8251979B2 (en) 2009-05-11 2012-08-28 Tyco Healthcare Group Lp Orientation independent canister for a negative pressure wound therapy device
WO2010056977A2 (en) * 2008-11-14 2010-05-20 Kci Licensing, Inc. Fluid pouch, system, and method for storing fluid from a tissue site
US9421309B2 (en) 2009-06-02 2016-08-23 Kci Licensing, Inc. Reduced-pressure treatment systems and methods employing hydrogel reservoir members
US8690844B2 (en) 2009-08-27 2014-04-08 Kci Licensing, Inc. Re-epithelialization wound dressings and systems
US9358158B2 (en) * 2010-03-16 2016-06-07 Kci Licensing, Inc. Patterned neo-epithelialization dressings, systems, and methods
US8403902B2 (en) * 2010-05-18 2013-03-26 Kci Licensing, Inc. Reduced-pressure medical systems and methods employing a moisture processing device
US8795257B2 (en) * 2010-07-19 2014-08-05 Kci Licensing, Inc. Systems and methods for electrically detecting the presence of exudate in dressings
CN107185061B (zh) * 2010-08-18 2021-01-22 凯希特许有限公司 减压的多方位液体收集罐

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001085248A1 (en) * 2000-05-09 2001-11-15 Kci Licensing, Inc. Abdominal wound dressing
US20050085795A1 (en) * 2002-02-28 2005-04-21 Lockwood Jeffrey S. External catheter access to vacuum bandage
WO2004037334A1 (en) * 2002-10-28 2004-05-06 Smith & Nephew Plc Apparatus for aspirating, irrigating and cleansing wounds
WO2008141228A1 (en) * 2007-05-10 2008-11-20 Kci Licensing Inc. Reduced pressure wound dressing having a wound contact surface with columnar protrusions

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12121417B2 (en) 2009-02-13 2024-10-22 Smith & Nephew Plc Negative pressure wound treatment apparatus
US11357903B2 (en) 2009-02-13 2022-06-14 Smith & Nephew Plc Wound packing
EP2470135B1 (en) 2009-08-27 2016-10-12 KCI Licensing, Inc. Re-epithelialization wound dressings and systems
US12186476B2 (en) 2010-02-26 2025-01-07 Smith & Nephew, Inc. Systems and methods for using negative pressure wound therapy to manage open abdominal wounds
US11484443B2 (en) 2010-02-26 2022-11-01 Smith & Nephew, Inc. Systems and methods for using negative pressure wound therapy to manage open abdominal wounds
CN103702646B (zh) * 2011-06-24 2016-03-30 凯希特许有限公司 采用组织固定元件的减压敷件
AU2012333210B2 (en) * 2011-06-24 2017-01-19 Solventum Intellectual Properties Company Reduced-pressure dressings employing tissue-fixation elements
JP2019188163A (ja) * 2011-06-24 2019-10-31 ケーシーアイ ライセンシング インコーポレイテッド 組織固定要素を採用する減圧ドレッシング
US10973696B2 (en) 2011-06-24 2021-04-13 Kci Licensing, Inc. Reduced-pressure dressings employing tissue-fixation elements
WO2013066426A3 (en) * 2011-06-24 2013-09-06 Kci Licensing, Inc. Reduced-pressure dressings employing tissue-fixation elements
US11364152B2 (en) 2011-06-24 2022-06-21 Kci Licensing, Inc. Reduced-pressure dressings employing tissue-fixation elements
US9168179B2 (en) 2011-06-24 2015-10-27 Kci Licensing, Inc. Reduced-pressure dressings employing tissue-fixation elements
US11850351B2 (en) 2011-06-24 2023-12-26 3M Innovative Properties Company Reduced-pressure dressings employing tissue-fixation elements
JP2014519960A (ja) * 2011-06-24 2014-08-21 ケーシーアイ ライセンシング インコーポレイテッド 組織固定要素を採用する減圧ドレッシング
CN103702646A (zh) * 2011-06-24 2014-04-02 凯希特许有限公司 采用组织固定元件的减压敷件
EP2879636B1 (en) 2012-08-01 2017-03-22 Smith & Nephew PLC Wound dressing
US11771796B2 (en) 2013-03-15 2023-10-03 Smith & Nephew Plc Wound dressing and method of treatment
US11554051B2 (en) 2017-06-30 2023-01-17 T.J. Smith And Nephew, Limited Negative pressure wound therapy apparatus

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