WO2010123200A2 - 병원성 장내세균을 사멸시키는 박테리오파지 - Google Patents

병원성 장내세균을 사멸시키는 박테리오파지 Download PDF

Info

Publication number
WO2010123200A2
WO2010123200A2 PCT/KR2010/001359 KR2010001359W WO2010123200A2 WO 2010123200 A2 WO2010123200 A2 WO 2010123200A2 KR 2010001359 W KR2010001359 W KR 2010001359W WO 2010123200 A2 WO2010123200 A2 WO 2010123200A2
Authority
WO
WIPO (PCT)
Prior art keywords
bacteriophage
enteric bacteria
present
bacteria
pathogenic enteric
Prior art date
Application number
PCT/KR2010/001359
Other languages
English (en)
French (fr)
Other versions
WO2010123200A3 (ko
Inventor
김석호
김성훈
권혁준
이복권
김정민
Original Assignee
경북대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 경북대학교 산학협력단 filed Critical 경북대학교 산학협력단
Publication of WO2010123200A2 publication Critical patent/WO2010123200A2/ko
Publication of WO2010123200A3 publication Critical patent/WO2010123200A3/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

본 발명은 신규한 박테리오파지에 관한 것으로, 구체적으로 병원성 장내세균에 대한 사멸능을 갖고, 서열번호 1로 구성된 아미노산 서열을 코딩하는 추정상 헬리케이즈(Putative helicase) 유전자 서열을 갖는 박테리오파지(Bacteriophage) SS3e에 관한 것이다. 본 발명에 따르면, 상기 박테리오파지를 이용하여 대표적인 식품매개질환을 일으키는 원인균으로서 병원성 장내세균을 효과적으로 사멸시키거나 감소시킬 수 있다. 특히 박테리오파지는 세균을 숙주로 하는 바이러스로 사람과 동물 등에는 전혀 작용하지 않는 것으로 알려져 있기 때문에 의약산업, 식품산업, 생명공학 등에 응용이 가능할 뿐 아니라, 항생제 내성에 대한 문제점 없이 유해 장내세균을 목표장소 또는 목표물질에서 효과적으로 사멸시킬 수 있다.
PCT/KR2010/001359 2009-04-22 2010-03-04 병원성 장내세균을 사멸시키는 박테리오파지 WO2010123200A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020090034922A KR101101604B1 (ko) 2009-04-22 2009-04-22 병원성 장내세균을 사멸시키는 박테리오파지
KR10-2009-0034922 2009-04-22

Publications (2)

Publication Number Publication Date
WO2010123200A2 true WO2010123200A2 (ko) 2010-10-28
WO2010123200A3 WO2010123200A3 (ko) 2011-01-13

Family

ID=43011560

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/001359 WO2010123200A2 (ko) 2009-04-22 2010-03-04 병원성 장내세균을 사멸시키는 박테리오파지

Country Status (2)

Country Link
KR (1) KR101101604B1 (ko)
WO (1) WO2010123200A2 (ko)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013106455A1 (de) 2013-06-20 2014-12-24 Airbus Defence and Space GmbH Verfahren zur Dekontamination von bakteriologischen Verunreinigungen
CN107250352A (zh) * 2014-12-30 2017-10-13 尹特荣生物科技株式会社 新型肠致病性大肠杆菌噬菌体Esc‑CHP‑2及其用于抑制肠致病性大肠杆菌增殖的用途
US11058131B2 (en) 2015-04-16 2021-07-13 Kennesaw State University Research And Service Foundation, Inc. Escherichia coli O157:H7 bacteriophage Φ241
EP3795169A4 (en) * 2018-05-03 2022-03-02 Kyungpook National University Industry-Academic Cooperation Foundation RECOMBINANT PROTEIN DERIVED FROM A BACTERIOPHAGE WITH ANTIMICROBIAL ACTIVITY AGAINST PATHOGENIC GRAM-NEGATIVE BACTERIA

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101101376B1 (ko) * 2009-10-16 2012-01-02 경희대학교 산학협력단 대장균 또는 시겔라속 균에 특이적 사멸능을 갖는 박테리오파지
KR101101377B1 (ko) * 2009-10-16 2012-01-02 경희대학교 산학협력단 이질균에 특이적 사멸능을 갖는 박테리오파지
KR101299179B1 (ko) * 2012-04-18 2013-08-22 씨제이제일제당 (주) 신규 박테리오파지 및 이를 포함하는 항균 조성물
KR101381795B1 (ko) 2013-02-27 2014-04-07 씨제이제일제당 (주) 신규 박테리오파지 및 이를 포함하는 항균 조성물
KR101761573B1 (ko) * 2014-12-29 2017-07-26 주식회사 인트론바이오테크놀로지 신규한 장출혈성 대장균 박테리오파지 Ｅｓｃ-ＣＨＰ-1 및 이의 장출혈성 대장균 증식 억제 용도
RU2616257C9 (ru) * 2015-11-05 2017-07-24 Общество с ограниченной ответственностью "Фармактивы Капитал" Биологический способ селективной дезинфекции с использованием бактериофагов
KR101992013B1 (ko) 2017-08-16 2019-06-21 경북대학교 산학협력단 병원성 장내세균에 대해 사멸능을 갖는 신규 박테리오파지 및 이의 용도
KR101999916B1 (ko) 2018-01-19 2019-07-12 강릉원주대학교산학협력단 긴불레기말 추출물을 포함하는 근력 강화 또는 근감소증 예방 및 치료용 조성물
KR102592971B1 (ko) * 2023-06-15 2023-10-23 ㈜에스에이치랩 장내 미생물에 대한 박테리오파지를 포함하는 피부 보습 및 주름 개선용 조성물

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020090356A1 (en) * 2000-06-06 2002-07-11 Waddell Thomas E. Use of bacteriophages for control of escherichia coli 0 157
KR20090030532A (ko) * 2007-09-20 2009-03-25 재단법인서울대학교산학협력재단 시포비리대에 속하는 박테리오파지 및 이를 포함하는 세균사멸용 조성물

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020090356A1 (en) * 2000-06-06 2002-07-11 Waddell Thomas E. Use of bacteriophages for control of escherichia coli 0 157
KR20090030532A (ko) * 2007-09-20 2009-03-25 재단법인서울대학교산학협력재단 시포비리대에 속하는 박테리오파지 및 이를 포함하는 세균사멸용 조성물

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK 12 January 2005 Database accession no. AY730274 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013106455A1 (de) 2013-06-20 2014-12-24 Airbus Defence and Space GmbH Verfahren zur Dekontamination von bakteriologischen Verunreinigungen
EP2815652A2 (de) 2013-06-20 2014-12-24 Airbus Defence and Space GmbH Verfahren zur Dekontamination von bakteriologischen Verunreinigungen
CN107250352A (zh) * 2014-12-30 2017-10-13 尹特荣生物科技株式会社 新型肠致病性大肠杆菌噬菌体Esc‑CHP‑2及其用于抑制肠致病性大肠杆菌增殖的用途
CN107250352B (zh) * 2014-12-30 2021-02-09 尹特荣生物科技株式会社 新型肠致病性大肠杆菌噬菌体Esc-CHP-2及其用于抑制肠致病性大肠杆菌增殖的用途
US11058131B2 (en) 2015-04-16 2021-07-13 Kennesaw State University Research And Service Foundation, Inc. Escherichia coli O157:H7 bacteriophage Φ241
EP3795169A4 (en) * 2018-05-03 2022-03-02 Kyungpook National University Industry-Academic Cooperation Foundation RECOMBINANT PROTEIN DERIVED FROM A BACTERIOPHAGE WITH ANTIMICROBIAL ACTIVITY AGAINST PATHOGENIC GRAM-NEGATIVE BACTERIA

Also Published As

Publication number Publication date
KR101101604B1 (ko) 2012-01-02
WO2010123200A3 (ko) 2011-01-13
KR20100116289A (ko) 2010-11-01

Similar Documents

Publication Publication Date Title
WO2010123200A3 (ko) 병원성 장내세균을 사멸시키는 박테리오파지
Li et al. Plant antimicrobial peptides: structures, functions, and applications
Rather et al. Microbial biofilm: A matter of grave concern for human health and food industry
Frampton et al. Advances in bacteriophage-mediated control of plant pathogens
CA2856891C (en) Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded pathogenic antigen
MY148890A (en) Novel bacteriophage and antibacterial composition comprising the same
BRPI1011277B8 (pt) produto de bacteriocina lactobacillus pentosus, alimento e composições farmacêuticas contendo o mesmo e uso do mesmo
WO2010074433A3 (ko) 신규한 박테리오파지 및 이를 포함하는 항균 조성물
WO2008121830A3 (en) Phage receptor binding proteins for antibacterial therapy and other novel uses
WO2011028059A3 (en) Novel bacteriophage and antibacterial composition comprising the same
WO2012087037A3 (en) Novel bacteriophage and antibacterial composition comprising the same
WO2009089822A3 (de) Verwendung eines acetylsalicylsäuresalzes zur behandlung viraler infektionen
Islam et al. A systematic review from basics to omics on bacteriophage applications in poultry production and processing
Lee et al. Bacteriophage and endolysin engineering for biocontrol of food pathogens/pathogens in the food: recent advances and future trends
Radzikowski et al. Alternative solutions to antibiotics in mastitis treatment for dairy cows-a review.
Upadhyay et al. In vivo efficacy of trans-cinnamaldehyde, carvacrol, and thymol in attenuating Listeria monocytogenes infection in a Galleria mellonella model
CO2021014758A2 (es) Diversos usos del compuesto nanoparticulado de dióxido de titanio funcionalizado
WO2013041663A3 (de) Modifizierte apidaecinderivate als antibiotische peptide
WO2011155727A3 (ko) 살모넬라 콜레라수이스 또는 살모넬라 두블린 감염을 방지 및 처치하는 방법
WO2009158618A3 (en) Avian reoviridae
MY159790A (en) Highly bridged peptides from actinomadura namibiensis
Vineethkumar et al. Post-translationally modified frog skin-derived antimicrobial peptides are effective against Aeromonas sobria
WO2011028064A3 (en) Novel bacteriophage and antibacterial composition comprising the same
AP2012006180A0 (en) Picrorhiza kurroa extract for prevention, elimination and treatment of RNA viruses and infection or diseases caused by the same in humans, animals andin biotech industry.
Crowe Treating flu with skin of frog

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10767215

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 10767215

Country of ref document: EP

Kind code of ref document: A2