WO2010091649A4 - Composition pour absorption buccale de nicotine dans le but d'une désaccoutumance au tabac - Google Patents
Composition pour absorption buccale de nicotine dans le but d'une désaccoutumance au tabac Download PDFInfo
- Publication number
- WO2010091649A4 WO2010091649A4 PCT/CZ2010/000011 CZ2010000011W WO2010091649A4 WO 2010091649 A4 WO2010091649 A4 WO 2010091649A4 CZ 2010000011 W CZ2010000011 W CZ 2010000011W WO 2010091649 A4 WO2010091649 A4 WO 2010091649A4
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- weight
- nicotine
- substances
- concentration
- group
- Prior art date
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title claims abstract 9
- 229960002715 nicotine Drugs 0.000 title claims abstract 9
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title claims abstract 9
- 239000000203 mixture Substances 0.000 title claims abstract 8
- 238000010521 absorption reaction Methods 0.000 title claims abstract 3
- 230000005586 smoking cessation Effects 0.000 title claims abstract 3
- 239000000126 substance Substances 0.000 claims abstract 7
- 230000000510 mucolytic effect Effects 0.000 claims abstract 3
- 230000002411 adverse Effects 0.000 claims abstract 2
- 210000003169 central nervous system Anatomy 0.000 claims abstract 2
- 150000007524 organic acids Chemical class 0.000 claims abstract 2
- 150000003839 salts Chemical class 0.000 claims abstract 2
- 230000000391 smoking effect Effects 0.000 claims abstract 2
- 238000006467 substitution reaction Methods 0.000 claims abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 3
- 241000196324 Embryophyta Species 0.000 claims 2
- 244000072254 Primula veris Species 0.000 claims 2
- 235000002343 Primula veris Nutrition 0.000 claims 2
- 238000000605 extraction Methods 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- 244000163122 Curcuma domestica Species 0.000 claims 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- 244000166124 Eucalyptus globulus Species 0.000 claims 1
- 235000004692 Eucalyptus globulus Nutrition 0.000 claims 1
- 244000207620 Euterpe oleracea Species 0.000 claims 1
- 235000012601 Euterpe oleracea Nutrition 0.000 claims 1
- 239000005715 Fructose Substances 0.000 claims 1
- 229930091371 Fructose Natural products 0.000 claims 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims 1
- 244000194101 Ginkgo biloba Species 0.000 claims 1
- 235000008100 Ginkgo biloba Nutrition 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- 240000008669 Hedera helix Species 0.000 claims 1
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 claims 1
- 240000003394 Malpighia glabra Species 0.000 claims 1
- 235000014837 Malpighia glabra Nutrition 0.000 claims 1
- 229930195725 Mannitol Natural products 0.000 claims 1
- 244000131360 Morinda citrifolia Species 0.000 claims 1
- 235000008898 Morinda citrifolia Nutrition 0.000 claims 1
- 244000178231 Rosmarinus officinalis Species 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
- 244000269722 Thea sinensis Species 0.000 claims 1
- 235000006468 Thea sinensis Nutrition 0.000 claims 1
- 244000078534 Vaccinium myrtillus Species 0.000 claims 1
- 235000017537 Vaccinium myrtillus Nutrition 0.000 claims 1
- 240000006365 Vitis vinifera Species 0.000 claims 1
- 235000014787 Vitis vinifera Nutrition 0.000 claims 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims 1
- 229960004308 acetylcysteine Drugs 0.000 claims 1
- 229930014669 anthocyanidin Natural products 0.000 claims 1
- 235000008758 anthocyanidins Nutrition 0.000 claims 1
- 230000003064 anti-oxidating effect Effects 0.000 claims 1
- 239000004599 antimicrobial Substances 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 235000006708 antioxidants Nutrition 0.000 claims 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229920002770 condensed tannin Polymers 0.000 claims 1
- 235000003373 curcuma longa Nutrition 0.000 claims 1
- 235000013681 dietary sucrose Nutrition 0.000 claims 1
- 229930003949 flavanone Natural products 0.000 claims 1
- 235000011981 flavanones Nutrition 0.000 claims 1
- 150000002208 flavanones Chemical class 0.000 claims 1
- 229930003939 flavanonol Natural products 0.000 claims 1
- 150000002210 flavanonols Chemical class 0.000 claims 1
- 229930003944 flavone Natural products 0.000 claims 1
- 150000002213 flavones Chemical class 0.000 claims 1
- 235000011949 flavones Nutrition 0.000 claims 1
- HVQAJTFOCKOKIN-UHFFFAOYSA-N flavonol Natural products O1C2=CC=CC=C2C(=O)C(O)=C1C1=CC=CC=C1 HVQAJTFOCKOKIN-UHFFFAOYSA-N 0.000 claims 1
- 150000002216 flavonol derivatives Chemical class 0.000 claims 1
- 235000011957 flavonols Nutrition 0.000 claims 1
- NWKFECICNXDNOQ-UHFFFAOYSA-N flavylium Chemical compound C1=CC=CC=C1C1=CC=C(C=CC=C2)C2=[O+]1 NWKFECICNXDNOQ-UHFFFAOYSA-N 0.000 claims 1
- 229960002737 fructose Drugs 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 229960001031 glucose Drugs 0.000 claims 1
- 235000001727 glucose Nutrition 0.000 claims 1
- 235000002532 grape seed extract Nutrition 0.000 claims 1
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 claims 1
- 150000002515 isoflavone derivatives Chemical class 0.000 claims 1
- 235000008696 isoflavones Nutrition 0.000 claims 1
- 239000000594 mannitol Substances 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 229960001855 mannitol Drugs 0.000 claims 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 claims 1
- 229930014802 neoflavonoid Natural products 0.000 claims 1
- 150000002804 neoflavonoids Chemical class 0.000 claims 1
- 235000017524 noni Nutrition 0.000 claims 1
- 230000008447 perception Effects 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 235000015639 rosmarinus officinalis Nutrition 0.000 claims 1
- 230000014860 sensory perception of taste Effects 0.000 claims 1
- 239000003352 sequestering agent Substances 0.000 claims 1
- 229960004793 sucrose Drugs 0.000 claims 1
- 150000005846 sugar alcohols Polymers 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 239000000811 xylitol Substances 0.000 claims 1
- 235000010447 xylitol Nutrition 0.000 claims 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims 1
- 229960002675 xylitol Drugs 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Addiction (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Dispersion Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention a pour objet une composition destinée à une absorption buccale de nicotine dans la circulation systémique et à une distribution au système nerveux central dans le but d'une désaccoutumance au tabac ou d'une substitution nicotinique dans des conditions hostiles au tabac. La composition contient une solution de nicotine se présentant sous la forme d'une base et/ou de son sel avec un acide organique dans une concentration de 0,01 à 8,00 % en poids et des substances ayant un effet mucolytique. Une dose d'application unique contient de 0,05 à 3,00 mg de nicotine.
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2010213244A AU2010213244A1 (en) | 2009-02-11 | 2010-02-03 | A composition for buccal absorption of nicotine for the purpose of smoking cessation |
| SG2011039500A SG171870A1 (en) | 2009-02-11 | 2010-02-03 | A composition for buccal absorption of nicotine for the purpose of smoking cessation |
| CA2751271A CA2751271A1 (fr) | 2009-02-11 | 2010-02-03 | Composition pour absorption buccale de nicotine dans le but d'une desaccoutumance au tabac |
| ES10721627.7T ES2606546T3 (es) | 2009-02-11 | 2010-02-03 | Compuesto destinado a la absorción bucal de nicotina con el objetivo de dejar de fumar |
| CN2010800073110A CN102316850A (zh) | 2009-02-11 | 2010-02-03 | 一种用于戒烟的口腔吸收尼古丁组合物 |
| EA201100896A EA201100896A1 (ru) | 2009-02-11 | 2010-02-03 | Композиция, предназначенная для всасывания никотина из ротовой полости с целью прекратить курение |
| US13/147,597 US20110293535A1 (en) | 2009-02-11 | 2010-02-03 | Composition for buccal absorption of nicotine for the purpose of smoking cessation |
| JP2011548524A JP2012517402A (ja) | 2009-02-11 | 2010-02-03 | 禁煙を目的としたニコチンを頬側吸収するための組成物 |
| EP10721627.7A EP2395974B1 (fr) | 2009-02-11 | 2010-02-03 | Composition pour absorption buccale de nicotine dans le but d'une désaccoutumance au tabac |
| ZA2011/03096A ZA201103096B (en) | 2009-02-11 | 2011-04-28 | A composition for buccal absorption of nicotine for the purpose of smoking cessation |
| IL212720A IL212720A (en) | 2009-02-11 | 2011-05-05 | Nicotine preparation for the absorption of the cheek for smoking cessation |
| US16/563,824 US20200022905A1 (en) | 2009-02-11 | 2019-09-07 | Composition for buccal absorption of nicotine for the purpose of smoking cessation and method for administering |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CZ20090080A CZ200980A3 (cs) | 2009-02-11 | 2009-02-11 | Kompozice urcená k bukální absorpci nikotinu za úcelem odvykání kourení |
| CZPV2009-80 | 2009-02-11 | ||
| CZ2009829 | 2009-12-09 | ||
| CZPV2009-829 | 2009-12-09 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US13/147,597 A-371-Of-International US20110293535A1 (en) | 2009-02-11 | 2010-02-03 | Composition for buccal absorption of nicotine for the purpose of smoking cessation |
| US16/563,824 Continuation US20200022905A1 (en) | 2009-02-11 | 2019-09-07 | Composition for buccal absorption of nicotine for the purpose of smoking cessation and method for administering |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| WO2010091649A2 WO2010091649A2 (fr) | 2010-08-19 |
| WO2010091649A3 WO2010091649A3 (fr) | 2010-11-11 |
| WO2010091649A4 true WO2010091649A4 (fr) | 2010-12-29 |
Family
ID=69162740
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CZ2010/000011 WO2010091649A2 (fr) | 2009-02-11 | 2010-02-03 | Composition pour absorption buccale de nicotine dans le but d'une désaccoutumance au tabac |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20110293535A1 (fr) |
| EP (1) | EP2395974B1 (fr) |
| JP (1) | JP2012517402A (fr) |
| KR (1) | KR20110114552A (fr) |
| CN (1) | CN102316850A (fr) |
| AU (1) | AU2010213244A1 (fr) |
| CA (1) | CA2751271A1 (fr) |
| EA (1) | EA201100896A1 (fr) |
| ES (1) | ES2606546T3 (fr) |
| IL (1) | IL212720A (fr) |
| PT (1) | PT2395974T (fr) |
| SG (1) | SG171870A1 (fr) |
| WO (1) | WO2010091649A2 (fr) |
| ZA (1) | ZA201103096B (fr) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10244793B2 (en) | 2005-07-19 | 2019-04-02 | Juul Labs, Inc. | Devices for vaporization of a substance |
| US20140166028A1 (en) * | 2012-12-14 | 2014-06-19 | Richard C. Fuisz | Enhanced Delivery of Nicotine, THC, Tobacco, Cannabidiol or Base Alkaloid from an Electronic Cigarette or Other Vapor or Smoke Producing Device Through Use of an Absorption Conditioning Unit |
| US20140166027A1 (en) * | 2012-12-14 | 2014-06-19 | Richard C. Fuisz | Enhanced Delivery of Nicotine, THC, Tobacco, Cannabidiol or Base Alkaloid from an Electronic Cigarette or Other Vapor Producing Device Through Use of an Absorption Conditioning Unit |
| MX2015015175A (es) | 2013-05-06 | 2016-01-12 | Pax Labs Inc | Formulaciones de sal de nicotina para dispositivos de aerosol y metodos de los mismos. |
| US9597298B2 (en) * | 2013-06-07 | 2017-03-21 | Remi Shrivastava | Composition for topical application comprising glycerol and tannins |
| EP3076805A4 (fr) | 2013-12-05 | 2017-10-11 | PAX Labs, Inc. | Formulations liquides de nicotine pour dispositifs générateurs d'aérosol et procédés correspondants |
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| CN104770864B (zh) * | 2015-02-13 | 2016-08-24 | 华健 | 一种清热润喉的电子雾化液及其制备方法 |
| WO2016133890A1 (fr) * | 2015-02-19 | 2016-08-25 | Srq Patent Holdings, Llc | Compositions pour cigarettes électroniques |
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| MX2018009703A (es) | 2016-02-11 | 2019-07-08 | Juul Labs Inc | Cartuchos de fijacion segura para dispositivos vaporizadores. |
| US10405582B2 (en) | 2016-03-10 | 2019-09-10 | Pax Labs, Inc. | Vaporization device with lip sensing |
| USD849996S1 (en) | 2016-06-16 | 2019-05-28 | Pax Labs, Inc. | Vaporizer cartridge |
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| USD851830S1 (en) | 2016-06-23 | 2019-06-18 | Pax Labs, Inc. | Combined vaporizer tamp and pick tool |
| USD887632S1 (en) | 2017-09-14 | 2020-06-16 | Pax Labs, Inc. | Vaporizer cartridge |
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| CN111000283A (zh) * | 2019-12-13 | 2020-04-14 | 武汉红金叶新材料科技有限公司 | 一种用于气溶胶装置的电子烟油及其制备方法和应用 |
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| CN116649576A (zh) * | 2023-06-14 | 2023-08-29 | 深圳市吉迩科技有限公司 | 一种含有抑菌抗氧化组合物的尼古丁口含制品及其制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63196524A (ja) * | 1987-02-10 | 1988-08-15 | Wakunaga Pharmaceut Co Ltd | 経粘膜吸収型制ガン作用調節剤 |
| IT1265312B1 (it) * | 1993-12-21 | 1996-10-31 | Indena Spa | Formulazioni contenenti carotenoidi e procarotenoidi associati a polifenoli nella prevenzione dei danni da abnorme produzione di |
| WO1997038662A2 (fr) * | 1996-04-12 | 1997-10-23 | Flemington Pharmaceutical Corporation | Pulverisateur ou capsule polaire d'aerosols buccaux |
| US20080138399A1 (en) * | 1999-07-16 | 2008-06-12 | Aradigm Corporation | Dual release nicotine formulations, and systems and methods for their use |
| US6277855B1 (en) * | 2000-04-21 | 2001-08-21 | Inspire Pharmaceuticals, Inc. | Method of treating dry eye disease with nicotinic acetylcholine receptor agonists |
| US20040002520A1 (en) * | 2002-07-01 | 2004-01-01 | Soderlund Patrick L. | Composition and method for cessation of Nicotine cravings |
| AU2005247369A1 (en) * | 2004-05-10 | 2005-12-08 | Mdrna, Inc. | Compositions and methods for enhanced mucosal delivery of parathyroid hormone |
| JP5296557B2 (ja) * | 2006-02-13 | 2013-09-25 | オリエント ファーマ（サモア）カンパニー，リミティド | 流涎症の治療のためのアルファ−２受容体アゴニスト（クロニジン）と抗ムスカリン剤（オキシブチニン）との組み合わせ |
| WO2008069972A2 (fr) * | 2006-12-01 | 2008-06-12 | Aradigm Corporation | Systèmes destinés à mettre fin à l'usage du tabac |
| US20080286340A1 (en) * | 2007-05-16 | 2008-11-20 | Sven-Borje Andersson | Buffered nicotine containing products |
| GB0712308D0 (en) * | 2007-06-25 | 2007-08-01 | Kind Group Ltd | An inhalable composition |
-
2010
- 2010-02-03 SG SG2011039500A patent/SG171870A1/en unknown
- 2010-02-03 CN CN2010800073110A patent/CN102316850A/zh active Pending
- 2010-02-03 JP JP2011548524A patent/JP2012517402A/ja active Pending
- 2010-02-03 WO PCT/CZ2010/000011 patent/WO2010091649A2/fr active Application Filing
- 2010-02-03 CA CA2751271A patent/CA2751271A1/fr not_active Abandoned
- 2010-02-03 AU AU2010213244A patent/AU2010213244A1/en not_active Abandoned
- 2010-02-03 EA EA201100896A patent/EA201100896A1/ru unknown
- 2010-02-03 KR KR1020117015113A patent/KR20110114552A/ko not_active Application Discontinuation
- 2010-02-03 PT PT107216277T patent/PT2395974T/pt unknown
- 2010-02-03 US US13/147,597 patent/US20110293535A1/en not_active Abandoned
- 2010-02-03 ES ES10721627.7T patent/ES2606546T3/es active Active
- 2010-02-03 EP EP10721627.7A patent/EP2395974B1/fr active Active
-
2011
- 2011-04-28 ZA ZA2011/03096A patent/ZA201103096B/en unknown
- 2011-05-05 IL IL212720A patent/IL212720A/en active IP Right Grant
-
2019
- 2019-09-07 US US16/563,824 patent/US20200022905A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20110114552A (ko) | 2011-10-19 |
| ZA201103096B (en) | 2011-12-28 |
| JP2012517402A (ja) | 2012-08-02 |
| SG171870A1 (en) | 2011-07-28 |
| EP2395974B1 (fr) | 2016-09-07 |
| WO2010091649A3 (fr) | 2010-11-11 |
| IL212720A (en) | 2016-02-29 |
| CA2751271A1 (fr) | 2010-08-19 |
| EP2395974A2 (fr) | 2011-12-21 |
| AU2010213244A1 (en) | 2010-08-19 |
| WO2010091649A2 (fr) | 2010-08-19 |
| IL212720A0 (en) | 2011-07-31 |
| US20200022905A1 (en) | 2020-01-23 |
| ES2606546T3 (es) | 2017-03-24 |
| US20110293535A1 (en) | 2011-12-01 |
| EA201100896A1 (ru) | 2012-01-30 |
| PT2395974T (pt) | 2016-12-14 |
| CN102316850A (zh) | 2012-01-11 |
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