WO2010067617A1 - Structure de membrane lipidique - Google Patents
Structure de membrane lipidique Download PDFInfo
- Publication number
- WO2010067617A1 WO2010067617A1 PCT/JP2009/006783 JP2009006783W WO2010067617A1 WO 2010067617 A1 WO2010067617 A1 WO 2010067617A1 JP 2009006783 W JP2009006783 W JP 2009006783W WO 2010067617 A1 WO2010067617 A1 WO 2010067617A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- lipid membrane
- membrane structure
- lipid
- gene
- gala
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
- A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
L'invention porte sur une structure de membrane lipidique destinée à administrer une substance telle qu'un composant pharmaceutiquement efficace ou un acide nucléique à un tissu ou organe cible (par exemple, le foie). La structure de membrane lipidique se trouve sous la forme d'un liposome modifié en surface par un polymère MPC et GALA, ou similaire.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008-317377 | 2008-12-12 | ||
JP2008317377 | 2008-12-12 |
Publications (1)
Publication Number | Publication Date |
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WO2010067617A1 true WO2010067617A1 (fr) | 2010-06-17 |
Family
ID=42242609
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2009/006783 WO2010067617A1 (fr) | 2008-12-12 | 2009-12-11 | Structure de membrane lipidique |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2010067617A1 (fr) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012124688A1 (fr) * | 2011-03-14 | 2012-09-20 | 国立大学法人北海道大学 | Vecteur pour administration pulmonaire, agent d'induction, et utilisations |
CN103588933A (zh) * | 2013-10-10 | 2014-02-19 | 西北大学 | 多重仿生抗生物污染共聚物及其制备方法和应用 |
WO2018150429A1 (fr) * | 2017-02-16 | 2018-08-23 | Yeda Research And Development Co. Ltd. | Véhicules liposomaux pour l'administration de médicaments |
WO2019111415A1 (fr) * | 2017-12-08 | 2019-06-13 | ワミレスコスメティックス株式会社 | Vésicule cationisée, et composition associée |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06178930A (ja) * | 1992-12-15 | 1994-06-28 | Pola Chem Ind Inc | 被膜安定化リポソーム及びその製造方法 |
JP2000001416A (ja) * | 1998-06-12 | 2000-01-07 | Pola Chem Ind Inc | ポリオール含有リポソーム |
WO2008105178A1 (fr) * | 2007-02-28 | 2008-09-04 | National University Corporation Hokkaido University | Agent utilisé pour améliorer la résistance d'un liposome contre un constituant biologique et liposome modifié avec ledit agent |
-
2009
- 2009-12-11 WO PCT/JP2009/006783 patent/WO2010067617A1/fr active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06178930A (ja) * | 1992-12-15 | 1994-06-28 | Pola Chem Ind Inc | 被膜安定化リポソーム及びその製造方法 |
JP2000001416A (ja) * | 1998-06-12 | 2000-01-07 | Pola Chem Ind Inc | ポリオール含有リポソーム |
WO2008105178A1 (fr) * | 2007-02-28 | 2008-09-04 | National University Corporation Hokkaido University | Agent utilisé pour améliorer la résistance d'un liposome contre un constituant biologique et liposome modifié avec ledit agent |
Non-Patent Citations (3)
Title |
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HIDETAKA AKITA ET AL.: "Development of multifunctional envelope-type nano-device (MEND) based on the regulation of intracellular trafficking", DRUG DELIVERY SYSTEM, vol. 22-2, 7 June 2007 (2007-06-07), pages 115 - 122 * |
HIDEYOSHI HARASHIMA ET AL., YAKUGAKU ZASSHI, vol. 127, no. 10, 2007, pages 1655 - 1672 * |
KENTARO KOGURE ET AL., YAKUGAKU ZASSHI, vol. 128, no. 2, February 2008 (2008-02-01), pages 219 - 232 * |
Cited By (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012124688A1 (fr) * | 2011-03-14 | 2012-09-20 | 国立大学法人北海道大学 | Vecteur pour administration pulmonaire, agent d'induction, et utilisations |
JP5850915B2 (ja) * | 2011-03-14 | 2016-02-03 | 国立大学法人北海道大学 | 肺送達のためのベクター、導入剤及び使用 |
US9532950B2 (en) | 2011-03-14 | 2017-01-03 | National University Corporation Hokkaido University | Vector for pulmonary delivery, inducing agent, and uses |
CN103588933A (zh) * | 2013-10-10 | 2014-02-19 | 西北大学 | 多重仿生抗生物污染共聚物及其制备方法和应用 |
CN103588933B (zh) * | 2013-10-10 | 2016-09-07 | 西北大学 | 多重仿生抗生物污染共聚物及其制备方法和应用 |
CN110612097A (zh) * | 2017-02-16 | 2019-12-24 | 耶达研究及发展有限公司 | 脂质体药物递送媒介物 |
IL268714A (en) * | 2017-02-16 | 2019-10-31 | Klein Jacob | Liposome preparation for drug administration |
WO2018150429A1 (fr) * | 2017-02-16 | 2018-08-23 | Yeda Research And Development Co. Ltd. | Véhicules liposomaux pour l'administration de médicaments |
US11684578B2 (en) | 2017-02-16 | 2023-06-27 | Yeda Research And Development Co. Ltd. | Liposomic drug-delivery vehicles |
IL291628B1 (en) * | 2017-02-16 | 2023-09-01 | Yeda res & development co ltd | A liposomal preparation for drug administration |
CN110612097B (zh) * | 2017-02-16 | 2023-10-20 | 耶达研究及发展有限公司 | 脂质体药物递送媒介物 |
WO2019111415A1 (fr) * | 2017-12-08 | 2019-06-13 | ワミレスコスメティックス株式会社 | Vésicule cationisée, et composition associée |
JPWO2019111415A1 (ja) * | 2017-12-08 | 2020-04-02 | ワミレスコスメティックス株式会社 | カチオン化ベシクル及びその組成物 |
KR20200098560A (ko) * | 2017-12-08 | 2020-08-20 | 워밀레스 코스메틱스 가부시키가이샤 | 카티온화 베시클 및 그 조성물 |
CN111683650A (zh) * | 2017-12-08 | 2020-09-18 | 和美令须化妆品株式会社 | 阳离子化囊泡及其组合物 |
KR102281703B1 (ko) | 2017-12-08 | 2021-07-23 | 워밀레스 코스메틱스 가부시키가이샤 | 카티온화 베시클 및 그 조성물 |
CN111683650B (zh) * | 2017-12-08 | 2021-11-05 | 和美令须化妆品株式会社 | 阳离子化囊泡及其组合物 |
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