WO2010066364A1 - Procédé de réalisation d'un élément de fermeture - Google Patents
Procédé de réalisation d'un élément de fermeture Download PDFInfo
- Publication number
- WO2010066364A1 WO2010066364A1 PCT/EP2009/008542 EP2009008542W WO2010066364A1 WO 2010066364 A1 WO2010066364 A1 WO 2010066364A1 EP 2009008542 W EP2009008542 W EP 2009008542W WO 2010066364 A1 WO2010066364 A1 WO 2010066364A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sealing element
- closure
- die
- closure body
- compression
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/02—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles
- B29C43/14—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles in several steps
- B29C43/146—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles in several steps for making multilayered articles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1406—Septums, pierceable membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/02—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles
- B29C43/18—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles incorporating preformed parts or layers, e.g. compression moulding around inserts or for coating articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/32—Component parts, details or accessories; Auxiliary operations
- B29C43/36—Moulds for making articles of definite length, i.e. discrete articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D51/00—Closures not otherwise provided for
- B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/32—Component parts, details or accessories; Auxiliary operations
- B29C43/36—Moulds for making articles of definite length, i.e. discrete articles
- B29C43/361—Moulds for making articles of definite length, i.e. discrete articles with pressing members independently movable of the parts for opening or closing the mould, e.g. movable pistons
- B29C2043/3615—Forming elements, e.g. mandrels or rams or stampers or pistons or plungers or punching devices
- B29C2043/3618—Forming elements, e.g. mandrels or rams or stampers or pistons or plungers or punching devices plurality of counteracting elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/02—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles
- B29C43/04—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles using movable moulds
- B29C43/06—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles using movable moulds continuously movable in one direction, e.g. mounted on chains, belts
- B29C43/08—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles using movable moulds continuously movable in one direction, e.g. mounted on chains, belts with circular movement, e.g. mounted on rolls, turntables
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2021/00—Use of unspecified rubbers as moulding material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/56—Stoppers or lids for bottles, jars, or the like, e.g. closures
- B29L2031/565—Stoppers or lids for bottles, jars, or the like, e.g. closures for containers
Definitions
- the invention relates to a method for producing a closure for a preferably sterile medicament container, wherein the closure is composed of a prefabricated closure body and a prefabricated, elastic-soft sealing element inserted therein, the closure body being cup-shaped with a bottom and a wall and the bottom has at least one puncture opening, which is closed by the density element and through which a part of the sealing element in the position of use of the closure is accessible from the outside.
- the invention further relates to a closure for a preferably sterile medicament container, the closure being composed of a prefabricated closure body and a prefabricated, elastic-soft density element inserted therein, the closure body being cup-shaped with a bottom and a wall and the bottom at least a puncture opening, which is closed by the sealing element and through which a part of the sealing element m access position of the closure is accessible from the outside.
- the invention relates to a use of a TPE material.
- closures are known, for example, from DE 38 35 720 A1, wherein the closures described there are produced by first forming a closure body in the form a cap is produced and in a further manufacturing step in the same tool or a part thereof, the elastic-soft sealing element m is injected into the cap, and have proven themselves.
- the prefabricated cap guarantees a tight seal between the sealing element and the cap, which is necessary, for example, for a sterile medicament container, it requires expensive tools in the production process.
- closures for medical and pharmaceutical applications made of thermoplastic materials in the well-controlled injection molding of multi-nested injection molds.
- the invention has for its object to provide a manufacturing method for a closure of the type mentioned, which causes low production costs.
- the sealing element may be inserted at the position of use of the closure from the outside or from the inside into a receptacle of the closure body. If the sealing element is inserted from the outside, then even a larger part of the sealing element is accessible from the outside, as determined by the size of the sealing opening.
- the sealing opening or the sealing element can be protected by an additional cover, which is before the first
- the compression method can be set up and performed, for example, as a clocked method at one or more stations.
- a particularly cost-effective method results when the sealing element is produced by means of a continuous rotary compression method.
- connection can cohesively, in particular by Welding or gluing, positive or non-positive or otherwise produced.
- the cohesive connection can be formed, for example, after insertion.
- Connecting the sealing element with the closure body m take place in a common step. This can be achieved, for example, by melting parts of the sealing element and the closure body prior to insertion of the sealing element and solidifying again after insertion.
- the sealing element is inserted with a bias voltage m the closure body.
- the puncture holes introduced into the sealing element close automatically after removal of the cannula, needle or the like.
- the sealing element is formed disk-shaped.
- the sealing element is formed with a non-circular basic shape.
- a basic form here is understood to mean the geometric shape which results when ornamentation and more detailed designs such as noses, ribs and the like are disregarded.
- the sealing element thus describes the geometric body of a prism, in which the base surfaces through the front and the back of the sealing element and the shell is given by the circumference or the curved side surface of the sealing element. Out of round thus means that the base is not a circular disk, but deviates from a circular disk.
- the Base surface as a polygon or as an ellipse or generally oval shape or has approximately the shape of the figure Eight or a spectacle shape, which results from the envelope of an arrangement of two spaced-apart circles in a plane on.
- a tool with an embossing die and a die is used, wherein the embossing punch and the die are aligned by a rotation against each other.
- This rotation is designed such that a method of die and dies against each other is possible. Since the ⁇ nêt basic shape of the sealing element exact alignment of the die and stamping punch is necessary to each other, the die, the die and the rotation are preferably manufactured and mounted with an accuracy that a maximum relative angular displacement of the die against the die, the Angular misalignment describes a rotation angle around a straight line passing through the die and the stamper, allowing for less than 1 ° or even less than 0.5 °.
- the die has a receiving space for the material of the sealing element and that the die seals at its periphery the receiving space during the compression process.
- Special care is directed to the sealing of the receiving space at intermediate spaces between moving parts, such as the die and / or the die and its associated guide elements and / or other moving parts, which limit the receiving space, to exclude burrs as much as possible. It is particularly favorable when a die and an embossing stamp are used whose effective ranges are identical. This results in a sealing element which has two identical sides and can therefore be used for different orientations in the closure body. As a result, method steps are saved when positioning the sealing element during insertion m the closure body.
- a front and a back are formed with matching shape.
- the sealing element for insertion into the closure body has therefore not required to be checked whether the sealing element is oriented correctly, ie whether the front side and not the rear side are facing the closure body
- Control steps and elaborate control devices are dispensed with.
- an effective direction of the die or of the die is provided on the die and / or on the die
- Embossing stamp sliding sleeve is arranged.
- a displaceable sleeve is arranged on the die and the punch. It is particularly favorable when each sleeve sealingly encloses the die or the stamping die at its periphery, so that no material can escape during the compression process and form a material burr.
- the sleeve in the compression method forms a lateral boundary of the sealing element, in particular the circumference of the sealing element.
- the sleeve encloses tightly the die or the die.
- the sealing element is made of TPE material. It has been found that TPE material is particularly suitable for the production of the sealing element and for its further performance characteristics.
- the sealing element is produced in the compression method m its use form. There is thus no post-processing, in particular no removal of a sprue point or a punching burr and no reworking of surfaces of the sealing element required.
- the sealing element consists of a molded TPE material in the compression process.
- the sealing element thus has no gate point.
- the compression method may in this case be designed so that the sealing element is formed free of cutting edges.
- the advantage here is that the sealing element does not form any interfering particles due to chipping material of sprue points or punched edges or surfaces. As a result, the handling of the sealing elements is simplified, whereby the manufacturing costs can be kept low.
- the sealing element has a bias in the closure body.
- the sealing element may, for example, be disc-shaped, especially with a non-circular basic shape.
- the sealing element is formed so symmetrically that the sealing element in at least two Orien- tions in the closure body can be used.
- the sealing element has a front side and a rear side, wherein the sealing element can be inserted into the closure body both with the front side and with the rear side toward the bottom side of the closure body.
- the sealing element has a further symmetry, which allows insertion with the front or with the back in two orientations.
- the closure body is preferably made of a non-elastic plastic, for example a fusible plastic, ie a thermoplastic material.
- the sealing element is preferably made of a rubber material or a thermoplastic elastomer (TPE).
- the invention thus provides a TPE material for a sealing element in a method according to the invention and / or for a sealing element of a closure produced by a method according to the invention and / or for a sealing element of a closure according to the invention.
- the invention will now be described with reference to an embodiment, but is not limited to this embodiment. Further embodiments result from combining the features of the claims with each other and / or with the features of this embodiment.
- FIG. 1 shows a closure body of a closure for a medicament container m a three-dimensional side view
- FIG. 2 shows the closure body according to FIG. 1 m in a three-dimensional, partially cutaway view of the inside of the closure body, FIG.
- FIG. 9 shows a carousel of a machine for carrying out a rotational compression method according to the invention.
- Fig. 1 shows a designated as a whole with 1 closure for a preferably sterile medicament container m a three-dimensional view of the outside in the use position side.
- Fig. 2 shows the shutter 1 m of a cut-three-dimensional view, which releases the view of the in use position of the closure 1 inside page.
- the closure 1 has a closure body 2, the off a prefabricated, hard material is made.
- the closure body 2 is thus non-elastic.
- the closure body 2 has a bottom 3 and a wall 4 and thus forms a cup-shaped part 5, in which a prefabricated sealing element 6 is inserted.
- the sealing element 6 is made of an elastic-soft material.
- a thermoplastic elastomer (TPE) is used.
- Puncture openings 7 m the bottom 3 is provided centered so that overall symmetry with respect
- the sealing element 6 abuts against the bottom 3 and therefore also extends m areas which are covered by the bottom 3 to the outside.
- the sealing openings 7 release areas of the sealing element 6, through which a part of the sealing element 6 in the position of use of the closure is accessible from the outside, for example with a needle or cannula or the like.
- the wall 5 is followed by a shoulder 8 and to this another wall 9 at.
- the wall 9 describes a larger diameter than the wall 4 and is of cylindrical shape, while the wall 4 has an oval basic shape.
- the sealing element 6 is disc-shaped with an oval basic shape. It therefore has a front side 11 and a rear side 12, in FIG. 2 the front side 11 facing the bottom 3.
- two cylindrical protuberances 10 are integrally formed on the front 11 and the back 12, which in the mounting position of the sealing element 6 in each case fit into a puncture opening 7.
- the sealing element 6 is formed symmetrically and the front 11 and back 12 are formed identical to each other, the back 12 can be introduced with the formed thereon protuberances 10 in the puncture openings 7.
- the sealing element 6 can thus be mounted on the closure body 2 in two orientations.
- the sealing element 6 in two orientations by rotation about an axis perpendicular to the front 11 axis by 180 ° into each other can be transferred, possible.
- the sealing element 6 is frictionally and cohesively, for example, by welding or gluing, connected to the closure body 2.
- a bias voltage is introduced into the sealing element 6, which is maintained in the inserted state.
- the sealing element can close 6 puncture holes m automatically.
- the sealing element 6 is prefabricated before insertion m the closure body 2 with a compression method, which will be described in more detail below.
- FIGS. 3 to 8 show different successive partial steps within a production cycle.
- the tool 13 has a die 14 and an embossing die 15 which are movable relative to each other.
- a sleeve 16 is arranged, which can slide on the lateral surface of the die 14 and is designed to be displaceable against the die 14.
- the sleeve 16 is thus displaceable in the direction indicated by an arrow effective direction 26 of the tool 13 and the die 14.
- the sleeve 16 has an oval basic shape, which is determined by the oval shape of the sealing element 6 m Fig. 2.
- the die 14 has the same oval basic shape and fits into the sleeve 16, so that no gap between the sleeve 16 and die 14 is released.
- a sleeve 17 is arranged, the identical to the sleeve 16 is formed.
- the sleeve 17 is slidably disposed on the die 15 in its direction of action 26.
- the sleeve 17 encloses the die 15 sealingly, so that no gap between the sleeve 17 and die 15 remains.
- the sleeves 16, 17 a receiving space 18 tightly enclosing by the mating, annular edges 19, 20 of the sleeves 16, 17 are brought by moving into contact with each other, as m Fig. 4 to 6 is shown. So that the non-round, ie oval edges 19, 20 close to each other, the die 15 and the die 14 are secured by a rotation not shown against relative rotation.
- a material lump 21 of TPE is inserted into this receiving space 18 to carry out the compression method m in a first partial step, before the sleeves 16, 17 close the receiving space 18.
- the lump of material 21 is in a warm state allowing deformation.
- the sealing element 6 is formed by the die 15 is moved against the die 14 with closed sleeves 16, 17, whereby the effective areas 22, 23 of die 14 and die 15 act on the material lump 21.
- the active region 22 thereby forms the front side 11 of the sealing element 6, while the active region 23 forms the rear side 12 of the sealing element 6.
- the manufactured sealing element Since the effective region 22 is designed to be identical to the effective region 23 and thus embosses a same shape as that, the manufactured sealing element has a symmetry which allows the sealing element 6 to be mounted on the closure body 2 in two orientations, namely with the front side 11 or with the back 12 to the bottom 3, allowed.
- the die 14 and the die 15 are formed identical to each other and interchangeable.
- the sleeves 16 and 17 are identical to each other.
- the sleeve 17 is moved on the die 17 until the edges 19 and 20 touch.
- the receiving space 18 is sealed to the outside, and there is the situation shown in FIG. 4th
- the embossing punch 15 and the die 14 are moved against each other until the remaining receiving space 18 is completely filled by the material lump 21. Since the sleeves 16, 17 on the die 14 and the die 15 are arranged displaceably, the die 14 and the die 15 but tightly enclose, the volume of the receiving portion 18 adapts to the respective position of the die 14 relative to the die 15 and no material of the material lump 21 can emerge from the receiving area 18. If the receiving region 18 is completely filled with the lump of material 21, the sealing element 6 is shaped, as can be seen in FIG. 5. The protuberances 10 are in this case through the recesses 24th shaped, the oval or non-circular periphery 25 of the sealing element 6 through the inner wall of the sleeve 17th
- sleeves 16, 17 are displaced in this sub-step so that the contacting edges 19, 20 pass outside the remaining receiving space 18.
- burrs on the sealing element 6 in the region of these edges 19, 20 are avoided.
- a next sub-step for example, after a cooling phase in which the temperature of the sealing element 6 drops below the limit of deformability, die 14 and die 15 are moved apart, whereby the molded sealing element 6 m of the receptacle 18 released and only through the sleeve 17th is held.
- the end position of this partial step is shown in FIG. 6.
- the sealing element 6 is ejected.
- the embossing die 15 is displaced relative to the sleeve 17 holding the finished sealing element 6 until the effective region 23 engages the sealing element 6 and ejects it from the sleeve 17, as shown in FIG.
- the ejected sealing element 6 is now in use. A reworking of surfaces of the sealing element 6 is not required, since the receiving space 18 functioning as an isolated mold cavity has not formed any burrs or sprue points on the sealing element 6. Now the first sub-step for the production of the next sealing element 6 can join again.
- the partial steps shown can be set up on a carousel 27 of a machine for rotational compression method shown in FIG.
- the tools 13 are attached as stations to the plates 28, 29.
- the dies 14 are in this case movably mounted on the lower plate 28, while the dies 15 are movably arranged on the upper plate 29.
- the working positions shown in Figs. 3 to 8 are thus carried out by the individual tools 13 successively and in time with the rotational movement of the carousel 27, as m Fig. 9 it can be seen, wherein the sealing elements 6 each m the receiving spaces 18 are formed. Along the circumference of the plates 28, 29, the receiving spaces 18 are thus closed, and it is compressed. In the remaining portion of the receiving space is opened in each case, and it will eject the manufactured sealing elements 6 and it is inserted new material.
- each receiving space 18 has no connection to one another, so that each receiving space 18 forms an isolated mold cavity for the production of a sealing element 6 m in use.
- a groove-shaped anti-rotation device 32 in which a guide element of the respective embossing die 15 engages.
- This anti-rotation device 32 thus enables a defined opening and closing of the receiving space 18 and an actuation of the embossing die 15 against the die 14.
- a similar rotation is provided to guide the dies 14 on the lower plate 28.
- the sub-steps shown can also be executed in a clocked-operated method on a tool 13 or an arrangement of a plurality of tools 13.
- the die 14 is moved against the die 15.
- the embossing die 15 is moved against the die 14, or both the die 14 and the embossing die 15 are moved. The same applies to the movement of the sleeves 16, 17, since it depends on the relative movements in the first respect.
- a sealing element 6 is made of an elastic material in the compression method and m a cap-shaped, inelastic closure body 2 of the closure 1 is used.
- the sealing element 6 sealingly closes at least one puncture opening 7 m in the closure body 2 and allows insertion of a needle or cannula or the like into the medicament container closed with the closure 1.
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Closures For Containers (AREA)
- Casting Or Compression Moulding Of Plastics Or The Like (AREA)
Abstract
La présente invention concerne un procédé de réalisation d'un élément de fermeture (1) destiné à un récipient à médicament de préférence stérile, un élément d'étanchéité (6) étant réalisé au moyen d'un procédé de compression à partir d'une matière élastique, et inséré dans un corps de fermeture (2) non élastique en forme de capuchon, de l'élément de fermeture (1). L'élément d'étanchéité (6) referme de manière hermétique au moins une ouverture de perforation (7) pratiquée dans le corps de fermeture (2) et permet l'introduction d'une aiguille, d'une canule ou analogue dans le récipient à médicament refermé par l'élément de fermeture (1).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102008060994A DE102008060994A1 (de) | 2008-12-09 | 2008-12-09 | Herstellungsverfahren für einen Verschluss |
DE102008060994.3 | 2008-12-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2010066364A1 true WO2010066364A1 (fr) | 2010-06-17 |
Family
ID=42078980
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2009/008542 WO2010066364A1 (fr) | 2008-12-09 | 2009-12-01 | Procédé de réalisation d'un élément de fermeture |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE102008060994A1 (fr) |
WO (1) | WO2010066364A1 (fr) |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3364890A (en) * | 1965-02-12 | 1968-01-23 | West Co | Container closure and method of making the same |
US4397706A (en) * | 1974-05-24 | 1983-08-09 | The West Company | Method for making molded articles |
EP0920967A1 (fr) * | 1997-12-05 | 1999-06-09 | Becton, Dickinson and Company | Procédé pour la fabrication d'un dispositif de fermeture |
JP2003275278A (ja) * | 2002-03-26 | 2003-09-30 | Naigai Kasei Kk | 医療用栓体および医療用キャップ |
CN2817836Y (zh) * | 2005-03-08 | 2006-09-20 | 田壮禾 | 医用复合塑料盖及其胶垫 |
US20070267776A1 (en) * | 2004-05-27 | 2007-11-22 | West Pharmaceutical Services, Inc. | Injection Port and Method of Making the Same |
US20080067704A1 (en) * | 2004-10-18 | 2008-03-20 | Riken | Micro-Molding Equipment and Micro-Molding Method |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2007777A1 (de) * | 1970-02-20 | 1971-09-02 | Dynamit Nobel Ag | Verfahren und Vorrichtung zur Her stellung von Formkorpern aus duro und/ oder thermoplastischen Rohstoffen |
DE3835720A1 (de) | 1988-10-20 | 1990-05-03 | Wimmer Pharma Gummi Gmbh | Verschluss fuer eine medikamentenflasche und verfahren zur herstellung dieses verschlusses |
DE29521025U1 (de) * | 1995-04-07 | 1996-08-01 | Alcoa Gmbh Verpackwerke | Geprägte Dichtungseinlage |
DE10311154A1 (de) * | 2003-03-14 | 2004-09-23 | Helvoet Pharma Belgium N.V. | Für pharmazeutische Verwendung dienende Überkappe mit Verschlussstopfen |
-
2008
- 2008-12-09 DE DE102008060994A patent/DE102008060994A1/de not_active Ceased
-
2009
- 2009-12-01 WO PCT/EP2009/008542 patent/WO2010066364A1/fr active Application Filing
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3364890A (en) * | 1965-02-12 | 1968-01-23 | West Co | Container closure and method of making the same |
US4397706A (en) * | 1974-05-24 | 1983-08-09 | The West Company | Method for making molded articles |
EP0920967A1 (fr) * | 1997-12-05 | 1999-06-09 | Becton, Dickinson and Company | Procédé pour la fabrication d'un dispositif de fermeture |
JP2003275278A (ja) * | 2002-03-26 | 2003-09-30 | Naigai Kasei Kk | 医療用栓体および医療用キャップ |
US20070267776A1 (en) * | 2004-05-27 | 2007-11-22 | West Pharmaceutical Services, Inc. | Injection Port and Method of Making the Same |
US20080067704A1 (en) * | 2004-10-18 | 2008-03-20 | Riken | Micro-Molding Equipment and Micro-Molding Method |
CN2817836Y (zh) * | 2005-03-08 | 2006-09-20 | 田壮禾 | 医用复合塑料盖及其胶垫 |
Non-Patent Citations (1)
Title |
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DATABASE WPI Week 200382, Derwent World Patents Index; AN 2003-884742, XP002579104 * |
Also Published As
Publication number | Publication date |
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DE102008060994A1 (de) | 2010-06-17 |
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