WO2010036023A3 - 실린지 형상의 배양관 및 이를 이용한 세포배양기 - Google Patents

실린지 형상의 배양관 및 이를 이용한 세포배양기 Download PDF

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Publication number
WO2010036023A3
WO2010036023A3 PCT/KR2009/005427 KR2009005427W WO2010036023A3 WO 2010036023 A3 WO2010036023 A3 WO 2010036023A3 KR 2009005427 W KR2009005427 W KR 2009005427W WO 2010036023 A3 WO2010036023 A3 WO 2010036023A3
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WIPO (PCT)
Prior art keywords
culture
tube
cell culture
culture apparatus
cell
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Application number
PCT/KR2009/005427
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English (en)
French (fr)
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WO2010036023A2 (ko
Inventor
홍석기
양시은
김경숙
윤현수
이태용
이진화
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코아스템(주)
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Publication date
Application filed by 코아스템(주) filed Critical 코아스템(주)
Priority to US13/120,986 priority Critical patent/US20110287529A1/en
Publication of WO2010036023A2 publication Critical patent/WO2010036023A2/ko
Publication of WO2010036023A3 publication Critical patent/WO2010036023A3/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/10—Rotating vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/08—Flask, bottle or test tube
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

본 발명은 대면적이 넓고 작업자가 원하는 크기로 변경 가능한 실린지 형상의 배양관과, 이러한 배양관을 다수 장착가능하도록 되어 있으며, 회동유닛에 의해 배양관 내에 배양액가 일정부분 채워진 상태에서 배양관 내주면 전체에 걸쳐 배양액이 미리 지정된 속도로 지속덕이고 부드럽게 접촉하면서 회전하도록 하여 교반 및 가스 공급과 가스교환비율을 증가시킬 수 있으며 배양액의 소모량을 감소시킬 수 있는 세포배양기에 관한 것이다. 본 발명에 따른 세포배양기는, 내부에 배양공간이 형성되어 있으며 배양공간으로 배양액이 유출입되는 유출홀이 양단부 중 적어도 어느 하나의 일단부에 형성되어 있으며, 일단부는 외측으로 갈수록 내경이 좁아지는 형상으로 형성된 배양관; 배양관 다수가 길이방향으로 수평하게 장착되며, 중앙에 형성된 회전축을 중심으로 회전가능한 회전지지부재; 및 회전지지부재를 회전축을 중심으로 회전시키기 위한 회동유닛을 포함한다.
PCT/KR2009/005427 2008-09-26 2009-09-23 실린지 형상의 배양관 및 이를 이용한 세포배양기 WO2010036023A2 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US13/120,986 US20110287529A1 (en) 2008-09-26 2009-09-23 Syringe-Shaped Culture Tube and Cell Culture Apparatus Using Same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0094821 2008-09-26
KR1020080094821A KR101103693B1 (ko) 2008-09-26 2008-09-26 실린지 형상의 배양관 및 이를 이용한 세포배양기

Publications (2)

Publication Number Publication Date
WO2010036023A2 WO2010036023A2 (ko) 2010-04-01
WO2010036023A3 true WO2010036023A3 (ko) 2010-07-15

Family

ID=42060270

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/005427 WO2010036023A2 (ko) 2008-09-26 2009-09-23 실린지 형상의 배양관 및 이를 이용한 세포배양기

Country Status (3)

Country Link
US (1) US20110287529A1 (ko)
KR (1) KR101103693B1 (ko)
WO (1) WO2010036023A2 (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105112294A (zh) * 2015-09-15 2015-12-02 重庆大学 一种同轴多培养器生物反应器
WO2017187680A1 (ja) * 2016-04-27 2017-11-02 株式会社ジェイテックコーポレーション 大量細胞培養システム及びそれに用いるベッセル間細胞液移送装置並びに回転細胞培養装置
JP6268342B2 (ja) * 2016-04-27 2018-01-31 株式会社ジェイテックコーポレーション 大量細胞培養システム及びそれに用いる回転細胞培養装置
KR101754751B1 (ko) * 2016-06-09 2017-07-20 주식회사 아리바이오 회전형 세포배양장치
US11958050B2 (en) * 2018-05-24 2024-04-16 John Collins Fluidic devices for closed cell culture applications under current good manufacturing practice
CN109022269B (zh) * 2018-10-16 2023-08-04 广东石油化工学院 多通道室内反硝化培养装置及其培养方法
US20210171892A1 (en) * 2019-12-04 2021-06-10 Scientific Industries, Inc. Roller Tube Culture System
KR102437985B1 (ko) * 2020-12-30 2022-08-29 중앙대학교 산학협력단 클리노스탯 및 이에 사용되는 배양디쉬
CN113061521A (zh) * 2021-04-06 2021-07-02 英诺维尔智能科技（苏州）有限公司 一种高效能细胞培养管

Citations (4)

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WO1996005285A1 (en) * 1994-08-16 1996-02-22 Powell Biological Machines Ltd. Cell culture apparatus
EP0947580A2 (en) * 1998-02-17 1999-10-06 Cellon S.A. A cell culture vessel
KR20020068786A (ko) * 2001-02-22 2002-08-28 백기엽 드럼형 공기부양식 생물배양기
KR20020088848A (ko) * 2001-05-21 2002-11-29 (주)코아바이오텍 세포배양관 및 이를 이용한 대량 세포배양기

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Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996005285A1 (en) * 1994-08-16 1996-02-22 Powell Biological Machines Ltd. Cell culture apparatus
EP0947580A2 (en) * 1998-02-17 1999-10-06 Cellon S.A. A cell culture vessel
KR20020068786A (ko) * 2001-02-22 2002-08-28 백기엽 드럼형 공기부양식 생물배양기
KR20020088848A (ko) * 2001-05-21 2002-11-29 (주)코아바이오텍 세포배양관 및 이를 이용한 대량 세포배양기

Also Published As

Publication number Publication date
KR20100035434A (ko) 2010-04-05
US20110287529A1 (en) 2011-11-24
KR101103693B1 (ko) 2012-01-11
WO2010036023A2 (ko) 2010-04-01

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