WO2010030111A3 - 스피루리나로부터 클로로필 ａ 및 클로린을 제조하는 방법 - Google Patents

스피루리나로부터 클로로필 ａ 및 클로린을 제조하는 방법 Download PDF

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Publication number
WO2010030111A3
WO2010030111A3 PCT/KR2009/005099 KR2009005099W WO2010030111A3 WO 2010030111 A3 WO2010030111 A3 WO 2010030111A3 KR 2009005099 W KR2009005099 W KR 2009005099W WO 2010030111 A3 WO2010030111 A3 WO 2010030111A3
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WO
WIPO (PCT)
Prior art keywords
chlorine
chlorophyll
spirulina
treatment
pheophytin
Prior art date
Application number
PCT/KR2009/005099
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English (en)
French (fr)
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WO2010030111A2 (ko
Inventor
박계신
이은희
김효준
Original Assignee
다이아텍코리아 주식회사
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Application filed by 다이아텍코리아 주식회사 filed Critical 다이아텍코리아 주식회사
Publication of WO2010030111A2 publication Critical patent/WO2010030111A2/ko
Publication of WO2010030111A3 publication Critical patent/WO2010030111A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/05—Chlorophycota or chlorophyta (green algae), e.g. Chlorella
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B01D11/0288—Applications, solvents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

본 발명은 스피루리나로부터 클로로필 a 및 클로린을 제조하는 방법에 관한 것으로, 더욱 상세하게는 스피루리나로부터 물과 에탄올을 이용한 침전방법, 또는 물과 아세톤을 이용한 침전방법을 통해 효율적으로 클로로필 a를 추출하고, 상기에서 수득한 클로로필 a에 산을 처리하여 클로로필 a로부터 마그네슘 이온을 제거함으로써 페오피틴(pheophytin) a를 수득하고 이어서 페오피틴 a에 염기를 처리하여 광민감제 클로린을 형성시키고 아세토니트릴과 산을 처리하여 산 클로린을 분리한 다음 염기를 처리하여 염<sup/>클로린을 수득하는 방법에 관한 것이다.
PCT/KR2009/005099 2008-09-09 2009-09-09 스피루리나로부터 클로로필 ａ 및 클로린을 제조하는 방법 WO2010030111A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020080088652A KR100896327B1 (ko) 2008-09-09 2008-09-09 스피루리나로부터 클로로필 ａ 및 클로린을 제조하는 방법
KR10-2008-0088652 2008-09-09

Publications (2)

Publication Number Publication Date
WO2010030111A2 WO2010030111A2 (ko) 2010-03-18
WO2010030111A3 true WO2010030111A3 (ko) 2010-06-24

Family

ID=40861773

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/005099 WO2010030111A2 (ko) 2008-09-09 2009-09-09 스피루리나로부터 클로로필 ａ 및 클로린을 제조하는 방법

Country Status (2)

Country Link
KR (1) KR100896327B1 (ko)
WO (1) WO2010030111A2 (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010151073A2 (ko) 2009-06-26 2010-12-29 주식회사 진코스 항암 화학요법제-클로린 유도체의 접합체, 이를 함유하는 광감작제 및 이를 포함하는 암 치료용 조성물
KR100950441B1 (ko) 2009-09-30 2010-04-02 주식회사 아큐텍 스피루리나로부터 클로로필 ａ 및 포토디타진을 제조하는 방법
KR101106756B1 (ko) * 2010-08-16 2012-01-18 다이아텍코리아 주식회사 스피루리나로부터 클로로필 ａ 및 광민감제 제조방법
CN102532146A (zh) * 2010-12-13 2012-07-04 依诺特生物能量控股公司 萃取叶绿素和检测叶绿素浓度的方法
MX2013011520A (es) * 2011-04-06 2014-01-08 Heliae Dev Llc Metodos para producir biocombustibles, clorofilas y carotenoides.
KR101138438B1 (ko) * 2011-08-05 2012-04-26 다이아텍코리아 주식회사 스피루리나로부터 클로로필 ａ 및 광민감제 제조방법
KR101138437B1 (ko) * 2011-08-05 2012-04-26 다이아텍코리아 주식회사 스피루리나로부터 클로로필 ａ 및 광민감제 제조방법
KR101834766B1 (ko) 2014-09-26 2018-03-08 대한민국 향상된 색택을 가지는 콩 유래 추출물
KR101965979B1 (ko) 2017-11-02 2019-04-04 서원대학교산학협력단 스피루리나로부터 클로로필을 추출하는 방법
KR102007675B1 (ko) * 2019-03-05 2019-08-06 한국해양과학기술원 스피룰리나 추출물 제조방법, 스피룰리나 추출물을 포함하는 인지능 개선용 약학적 조성물 및 건강기능식품

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000119548A (ja) * 1998-10-19 2000-04-25 Tokai Sangyo Kk スピルリナからの黄色色素の製造方法
JP2000154333A (ja) * 1998-11-20 2000-06-06 Tokai Sangyo Kk スピルリナからの色素の製造方法
WO2002078694A1 (fr) * 2001-03-30 2002-10-10 Obschestvo S Ogranichennoy Otvetstvennostju 'rada-Farma' Photosensibilisateur et procede pour produire ledit photosensibilisateur
WO2008054050A1 (en) * 2006-11-03 2008-05-08 Gwangju Institute Of Science And Technology METHODS FOR PREPARING CHLOROPHYLL a AND CHLORIN e 6

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000119548A (ja) * 1998-10-19 2000-04-25 Tokai Sangyo Kk スピルリナからの黄色色素の製造方法
JP2000154333A (ja) * 1998-11-20 2000-06-06 Tokai Sangyo Kk スピルリナからの色素の製造方法
WO2002078694A1 (fr) * 2001-03-30 2002-10-10 Obschestvo S Ogranichennoy Otvetstvennostju 'rada-Farma' Photosensibilisateur et procede pour produire ledit photosensibilisateur
WO2008054050A1 (en) * 2006-11-03 2008-05-08 Gwangju Institute Of Science And Technology METHODS FOR PREPARING CHLOROPHYLL a AND CHLORIN e 6

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Publication number Publication date
WO2010030111A2 (ko) 2010-03-18
KR100896327B1 (ko) 2009-05-07

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