WO2010014682A3 - Système à courant continu pour l’identification et l’authentification de marqueurs - Google Patents

Système à courant continu pour l’identification et l’authentification de marqueurs Download PDF

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Publication number
WO2010014682A3
WO2010014682A3 PCT/US2009/052069 US2009052069W WO2010014682A3 WO 2010014682 A3 WO2010014682 A3 WO 2010014682A3 US 2009052069 W US2009052069 W US 2009052069W WO 2010014682 A3 WO2010014682 A3 WO 2010014682A3
Authority
WO
WIPO (PCT)
Prior art keywords
marker
plug flow
identification
transfer agent
transfer
Prior art date
Application number
PCT/US2009/052069
Other languages
English (en)
Other versions
WO2010014682A2 (fr
Inventor
Ian Eastwood
Erwin Dorland
Andrew Taylor
Original Assignee
Authentix, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Authentix, Inc. filed Critical Authentix, Inc.
Priority to EP09748162A priority Critical patent/EP2334395A2/fr
Publication of WO2010014682A2 publication Critical patent/WO2010014682A2/fr
Publication of WO2010014682A3 publication Critical patent/WO2010014682A3/fr
Priority to ZA2011/00895A priority patent/ZA201100895B/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0496—Solvent extraction of solutions which are liquid by extraction in microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0636—Focussing flows, e.g. to laminate flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0673—Handling of plugs of fluid surrounded by immiscible fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Extraction Or Liquid Replacement (AREA)

Abstract

La présente invention concerne des dispositifs et des procédés permettant d’extraire, d’identifier, d’authentifier et de quantifier un ou plusieurs marqueurs discrets dans un matériau. Un système d’extraction se compose d’un premier malaxeur à courant continu destiné à mélanger un premier fluide contenant un marqueur et un agent de transfert dans un courant continu. Le mélange et l’écoulement des liquides non miscibles provoquent le transfert du marqueur du fluide vers l’agent de transfert. Un robinet diviseur doté de filtres présentant différentes énergies de surface sépare les deux liquides non miscibles et l’agent de transfert contenant le marqueur. Il est possible d’utiliser un second courant continu pour transférer le marqueur vers un second agent de transfert. Le marqueur transféré est détecté afin d’authentifier le fluide original. Le marqueur peut également être isolé, activé ou peut réagir afin de réaliser une détection, identification ou authentification. Grâce à ce dispositif, plusieurs étapes indépendantes relatives au traitement et à l’analyse peuvent être combinées en une seule unité portative.
PCT/US2009/052069 2008-07-30 2009-07-29 Système à courant continu pour l’identification et l’authentification de marqueurs WO2010014682A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP09748162A EP2334395A2 (fr) 2008-07-30 2009-07-29 Systeme a ecoulement piston pour l'identification et authentification de marqueurs
ZA2011/00895A ZA201100895B (en) 2008-07-30 2011-02-03 Plug flow system for identification and authentification of markers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/182,749 2008-07-30
US12/182,749 US8354069B2 (en) 2005-03-08 2008-07-30 Plug flow system for identification and authentication of markers

Publications (2)

Publication Number Publication Date
WO2010014682A2 WO2010014682A2 (fr) 2010-02-04
WO2010014682A3 true WO2010014682A3 (fr) 2010-05-27

Family

ID=41611296

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/052069 WO2010014682A2 (fr) 2008-07-30 2009-07-29 Système à courant continu pour l’identification et l’authentification de marqueurs

Country Status (4)

Country Link
US (1) US8354069B2 (fr)
EP (1) EP2334395A2 (fr)
WO (1) WO2010014682A2 (fr)
ZA (1) ZA201100895B (fr)

Families Citing this family (8)

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Publication number Priority date Publication date Assignee Title
JP5622938B2 (ja) * 2010-09-09 2014-11-12 フラウンホッファー−ゲゼルシャフト ツァ フェルダールング デァ アンゲヴァンテン フォアシュンク エー．ファオ 微小流体デバイス、微小流体注入システム、および微小流体のフロー測定と注入の方法
EP2502674A1 (fr) * 2011-03-22 2012-09-26 Koninklijke Philips Electronics N.V. Procédé pour réaliser des réactions moléculaires en utilisant des fluides intermédiaires non miscibles
US9376676B2 (en) * 2012-09-07 2016-06-28 Agency For Science, Technology And Research Method of breaking down biological material
US9410937B2 (en) * 2013-09-28 2016-08-09 D-Z Inc. Method of operating a small-scale water separometer to pre-treat a filter prior to testing a fuel sample
CN112533272A (zh) * 2014-09-28 2021-03-19 华为技术有限公司 上行功率配置方法和装置
WO2017142678A1 (fr) * 2016-02-15 2017-08-24 Exxonmobil Research And Engineering Company Systèmes et procédés pour authentifier des fluides actifs
DE102017124091B4 (de) 2017-10-17 2019-08-01 Kraussmaffei Technologies Gmbh Scherteil und Einschnecken-Plastifiziereinheit
CN114307247B (zh) * 2021-12-13 2023-04-25 重庆安全技术职业学院 一种透过式固相微萃取微流控装置

Citations (4)

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US20040225249A1 (en) * 2003-03-14 2004-11-11 Leonard Edward F. Systems and methods of blood-based therapies having a microfluidic membraneless exchange device
WO2005028066A1 (fr) * 2003-08-30 2005-03-31 Roche Diagnostics Gmbh Dispositif pour separer un gaz ou un liquide de systemes d'ecoulement microfluidiques
WO2006096761A1 (fr) * 2005-03-08 2006-09-14 Authentix, Inc. Dispositif microfluidique d'identification, quantification, et authentification de marqueurs latents
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WO2005028066A1 (fr) * 2003-08-30 2005-03-31 Roche Diagnostics Gmbh Dispositif pour separer un gaz ou un liquide de systemes d'ecoulement microfluidiques
WO2006096761A1 (fr) * 2005-03-08 2006-09-14 Authentix, Inc. Dispositif microfluidique d'identification, quantification, et authentification de marqueurs latents
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US20090023223A1 (en) 2009-01-22

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