WO2010006537A1 - A pharmaceutical composition for treatment of livestock’s foot and mouth disease - Google Patents
A pharmaceutical composition for treatment of livestock’s foot and mouth disease Download PDFInfo
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- WO2010006537A1 WO2010006537A1 PCT/CN2009/072678 CN2009072678W WO2010006537A1 WO 2010006537 A1 WO2010006537 A1 WO 2010006537A1 CN 2009072678 W CN2009072678 W CN 2009072678W WO 2010006537 A1 WO2010006537 A1 WO 2010006537A1
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- parts
- grams
- mouth disease
- foot
- livestock
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- 241000710198 Foot-and-mouth disease virus Species 0.000 title claims abstract description 28
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/70—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Botany (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A pharmaceutical composition for treatment of livestock's foot and mouth disease. It can be made of Herba Scutellariae Barbatae 90-130 parts, Houttuyniae 90-130 parts, Isatidis 90-130 parts, Andrographis 90-130 parts, Radix Scutellariae 90-130 parts, Forsythiae 90-130 parts, Lonicerae 90-130 parts, Bletillae 90-130 parts, Sophorae 90-130 parts by weight.
Description
治疗牲畜口蹄疫的中草药 技术领域 Chinese herbal medicine for treating foot-and-mouth disease of livestock
本发明涉及一种牲畜疾病的治疗药物， 尤其涉及一种治疗牲畜口蹄疫 的中草药。 The invention relates to a medicine for treating livestock diseases, in particular to a Chinese herbal medicine for treating foot-and-mouth disease of livestock.
背景技术 Background technique
口蹄疫是偶蹄兽的一种快速传播的急性传染病， 症状主要是在口腔、 蹄部、 乳房以及鼻镜 （猪） 出现水疱和烂斑， 常能在短时间内形成大规模 流行造成严重的损失， 病源是口蹄疫病毒。 病毒具有多型性， 有甲型、 乙 型、 丙型、 亚洲型、 非洲型等主型、 各主型中又有亚型、 各型中又有亚型， 各型中间不能交互免疫， 在一个多型病毒存在地区牲畜患过一型口蹄疫之 后还会被另一型感染而发病， 经消化道、 呼吸道感染， 潜伏期为二至七天 的可达 14-21 天。 口蹄疫主要侵害牛、 猪、 绵羊、 山羊、 骆驼、 鹿等偶蹄 动物， 人也会偶尔感染， 单蹄动物不感染， 传播快呈小或大流行性， 每年 多发生春、 夏、 冬季节， 死亡率很高， 犊牛、 羔羊、 仔猪发病一般多为恶 性的， 死亡率极高。 口蹄疫的症状为： （1 ) 牛在舌面上或上下唇、 齿龈、 蹄部、 乳房等出现大小不等水疱。 体温急剧升高， 水疱破裂后留下边缘整 齐的烂斑体温之下降， 同时流出大量白色粘液； 猪的病变主要发生在蹄部， 有时口腔内和鼻镜上也发现水疱； 绵羊、 山羊也主要在蹄部有时在口腔内
发生水疱或烂斑、 哺乳母畜同时亦在乳房发生病变， 发病动物一般表现为 跛行和采食困难。 （2)幼畜 (犊牛、仔猪、 羔羊)往往发生无水疱性口蹄疫而 呈现心肌炎、 胃肠炎和四肢麻痹症状、 表现为腹泻或瘫痪， 有时无临床症 状而突然死亡， 剖检时可以看到急性心肌炎的变化、 心脏有灰红色或灰白 色斑紋， 称为虎斑心， 成年牲畜中死亡率 10-50%。 幼畜死亡率达 70-80%。 现有治疗口蹄疫大部分采用西药， 对口舌局病变部位， 采用 3%硼酸液洗涤 和来苏儿洗涤， 或用 1%过猛酸钾溶液涂洗， 有的用紫药水、 碘甘油、 松馏 油、 碘酒涂抹。 对严重症状的， 打强心脏针， 并结合西药疗法。 这些方法 均治标不治本。 目前对该病尚无根本性治疗药物。 部分地方注射疫苗预防， 但免疫迟缓、 免疫力短， 且如所用疫苗与流行病毒不同， 则不能起到预期 的免疫效果， 使疫情继续蔓延传染， 造成大批牲畜死亡、 影响牲畜繁殖和 产奶生长。 给国家和个人造成重大经济损失， 使国家或地区的副食品供应 紧张， 或影响田间的农业耕作， 严重危害畜牧业发展。 Foot-and-mouth disease is a rapidly spreading acute infectious disease of cloven-hoofed animals. The symptoms are mainly blistering and plaque in the mouth, hoof, breast and nose (porcine), which can cause serious losses in a short period of time. The source of the disease is foot-and-mouth disease virus. The virus is polymorphic, with major forms such as A, B, C, Asia, and Africa, subtypes in each major type, and subtypes in each type. In a region where a multi-type virus is present, a type of foot-and-mouth disease is also infected by another type of infection. After infection in the digestive tract and respiratory tract, the incubation period is two to seven days, up to 14-21 days. Foot-and-mouth disease mainly affects cloven-hoofed animals such as cattle, pigs, sheep, goats, camels, deer, etc., people also occasionally become infected, mono-hoofed animals are not infected, spread is small or pandemic, and spring, summer and winter seasons occur more often, death The rate is very high. The incidence of yak, lamb and piglets is generally malignant and the mortality rate is extremely high. The symptoms of foot-and-mouth disease are: (1) Buffs of varying sizes appear on the tongue or on the upper and lower lips, gums, hooves, breasts, etc. The body temperature rises sharply, and the blister rupture leaves a neat edge of the plaque, and a large amount of white mucus flows out; the lesions of the pig mainly occur in the hoof, and sometimes vesicles are found in the mouth and on the nose; sheep and goats are also mainly Sometimes in the mouth in the mouth Blisters or plaques occur, and lactating mothers also have lesions in the breasts. The affected animals are generally characterized by lameness and difficulty in eating. (2) Young animals (yak, piglets, lambs) often develop vesicular foot-and-mouth disease and present with symptoms of myocarditis, gastroenteritis and paralysis of the limbs, manifested as diarrhea or paralysis, sometimes sudden death without clinical symptoms, can be seen during necropsy To the changes in acute myocarditis, the heart has gray-red or gray-white markings, called the tiger spot heart, and the mortality rate in adult animals is 10-50%. The mortality rate of young animals is 70-80%. Most of the existing treatments for foot-and-mouth disease use Western medicine. The lesions of the tongue and tongue are washed with 3% boric acid solution and washed with Suer, or with 1% potassium permanganate solution. Some use purple syrup, iodine glycerol and turpentine oil. , iodine smeared. For severe symptoms, strengthen the heart needle and combine Western medicine. These methods are not cured. There are currently no fundamental treatments for this disease. In some places, vaccines are prevented, but the immunization is slow and the immunity is short. If the vaccine used is different from the epidemic virus, the expected immune effect will not be achieved, and the epidemic will continue to spread and spread, causing a large number of livestock to die, affecting livestock breeding and milk growth. . It causes major economic losses to the country and individuals, strains the supply of non-staple food in the country or region, or affects agricultural farming in the field, and seriously jeopardizes the development of animal husbandry.
发明内容 Summary of the invention
本发明涉及一种治疗牲畜口蹄疫的中草药， 它有利于杀灭口蹄疫病毒、 治疗牲畜口蹄疫病症。 The invention relates to a Chinese herbal medicine for treating foot-and-mouth disease of livestock, which is beneficial for killing foot-and-mouth disease virus and treating foot-and-mouth disease of livestock.
本发明技术方案是这样构成的， 其特征在于， 它包含以下重量份的中草 药： 半支莲 90-130份、 蕺菜 (鱼腥草) 90-130份、 板蓝根 90-130份、 穿心莲 90-130份、黄芩 90-130份、连翘 90-130份、金银花 90-130份、 白芨 90-130
份、 苦参 90-130份。 The technical solution of the present invention is constructed in that it comprises the following Chinese herbal medicines in weight: 90-130 parts of a half lotus, 90-130 parts of amaranth (Houttuynia cordata), 90-130 parts of Radix isatidis, and Andrographis paniculata 90- 130 parts, 90-130 parts of Astragalus, 90-130 pieces of Forsythia, 90-130 parts of honeysuckle, 90-130 of white peony Serve, 90-130 parts of Sophora flavescens.
本发明的中药配方是经过数十年改革实验总结下来的祖传偏方，具有疗 程较短、 使用简便易行、 成本低、 疗效显著的特点。 为了进一步缩短疗程、 提高疗效， 在本发明中草药的基础上也可再添加其它中草药。 The traditional Chinese medicine formula of the invention is an ancestral recipe which has been summarized through decades of reform experiments, and has the characteristics of short treatment period, simple and easy to use, low cost and remarkable curative effect. In order to further shorten the course of treatment and improve the curative effect, other Chinese herbal medicines may be added to the herbal medicine of the present invention.
(1) 在本药中君药是半支莲： 该药味辛性寒、 入肝、 肺、 胃、 肠， 具 有清热解毒， 抗病毒、 抗菌等作用常用于①瘟疫发热、 凉血消炎、 可治早期肺癌、 肝癌、 直肠癌等； ②利尿消肿， 可治疗肝硬化、 肝炎肝肿大， 痈肿疮毒、 皮肤肿毒等。 由于口蹄疫病原为口蹄疫 病毒， 故该药在本病中起到消灭病源口蹄疫病毒的治本作用。 (1) In this medicine, the drug is a half-branch: the drug is pungent, cold, liver, lung, stomach, intestine, has heat-clearing and detoxifying, anti-virus, anti-bacterial, etc. It is often used for 1 plague fever, cooling blood and anti-inflammatory, early treatment Lung cancer, liver cancer, rectal cancer, etc.; 2 diuretic swelling, can treat liver cirrhosis, hepatitis liver enlargement, swollen sore, skin swelling and so on. Since the foot-and-mouth disease is a foot-and-mouth disease virus, the drug plays a central role in eradicating the foot-and-mouth disease virus.
(2) 臣药蕺菜 (鱼腥草)：该药味辛性微寒、辛能发散，寒可清热、入肺、 胃、 心， 具有消肿解毒、 抗菌抗病毒、 内服为治痰热痈肺、 咳吐、 脓血的肺痈要药， 常用外用煎汤熏洗的方法来治疗各种病毒引起 的皮肤病感染， 疮疡中毒、 口舌糜烂以及各种疔疮皮肤菌等病症。 鱼腥草起杀灭口蹄疫病毒作用， 故在方中为臣药。 (2) medicinal herbs leeks (Houttuynia cordata): the drug tastes slightly cold, sin can be divergent, cold can clear heat, into the lungs, stomach, heart, with swelling and detoxification, antibacterial and antiviral, oral administration for treatment of phlegm and heat, Cough, pus and blood stasis drugs, commonly used external decoction fumigation method to treat various skin diseases caused by viruses, sore poisoning, tongue erosion and various acne skin bacteria and other diseases. Houttuynia has killed the foot-and-mouth disease virus, so it is a drug in the party.
(3) 臣药板蓝根： 该药味苦、 性寒入胃、 肺、 心， 具有清热、 解毒、 凉血消炎抗病毒作用， 常用于治疗风温湿毒、 瘟疫发热， 口面红 肿、 口舌溃烂， 病毒性感染等疾病。 板蓝根在本药中起抗口蹄疫 病毒的作用， 故在方中为臣药。 (3) The drug medicinal Banlangen: The drug tastes bitter, cold into the stomach, lungs, heart, has heat-clearing, detoxifying, cooling blood, anti-inflammatory and anti-viral effects, often used to treat wind-heat and dampness, plague fever, oral redness, mouth ulceration, Diseases such as viral infections. Banlangen plays a role in the anti-foot-and-mouth disease virus in this medicine, so it is a drug in Fangzhong.
(4) 臣药连翘： 味苦性微寒入胃、 肺、 心， 能抗菌消炎、 清热解毒、
消肿， 可治疗因热毒引起气血不能流通而产生痈肿疮毒等外症。 又有清心散热作用， 对多种皮肤杆菌有抑制与杀灭作用。 可治疗 温热病发热和心神不安。 (4) Chen medicine forsythia: bitter and slightly cold into the stomach, lungs, heart, antibacterial anti-inflammatory, detoxification, It can reduce the swelling, and can treat external diseases such as swollen sores caused by heat and toxic diseases. It also has a clear heat-dissipating effect and has a suppressing and killing effect on various skin bacilli. It can treat fever and fever.
(5) 臣药穿心莲： 味苦、 性寒， 具有清热解毒、 消肿止痛、 热毒能痊 的功能， 可治急性菌痢、 胃肠炎、 急性阑尾炎、 扁桃体炎、 咽喉 炎、 肺炎以及疮疖肿毒、 阴囊湿疹各种炎症。 (5) Herbal Medicine Andrographis paniculata: taste bitter, cold, has the functions of clearing away heat and detoxification, reducing swelling and relieving pain, and heat and poisoning. It can treat acute bacillary dysentery, gastroenteritis, acute appendicitis, tonsillitis, pharyngitis, pneumonia and sores. Swollen poison, scrotal eczema various inflammations.
(6) 佐药金银花： 味甘性寒， 有清热解毒作用， 对治疗痈肿疮毒有很 好的疗效， 痈肿疮毒初起， 未化脓时可以消肿， 已成脓时， 可以 托毒排脓， 促使早日疮破， 此药凉血止痢， 又能治血痢和风热感 冒。 (6) Adjuvant honeysuckle: sweet and cold, with heat-clearing and detoxifying effect, has a good curative effect on the treatment of swollen sore, swollen sore poison, can be swollen without pus, when it has become pus, it can be poisoned Pus, prompting early sore break, this medicine cools blood to stop phlegm, and can cure blood stasis and wind-heat cold.
(7) 佐药黄芩： 味苦、 性寒， 有生热燥湿作用、 清肺炎、 治肺热咳嗽、 清大肠火， 治大肠有热的痢疾泄泻， 凡是由湿热所引起的黄疸和 痈肿疮毒等症都可应用， 还有清热安胎作用。 (7) Adjuvant jaundice: bitter taste, cold, heat and dampness, clear pneumonia, lung heat cough, clear large intestine fire, cure dysentery and diarrhea in the large intestine, jaundice and phlegm caused by damp heat Swelling sores and other symptoms can be applied, as well as heat and fetus.
(8) 使药白芨： 味苦性平收敛止血， 有生肌消肿的作用， 能治痈肿毒 疮等症， 外敷治痈肿未成脓的可使之消散， 已溃的可使之生肌收 口， 特别对各种外科疾病有很好的疗效， 有补肺止血作用， 常用 于肺病和咳嗽。 (8) Make the drug white: The bitterness is flat and hemostasis, and it has the effect of reducing the swelling of the muscles. It can cure the swelling and sore embolism. The external application can cure the swelling and the pus can be dissipated. Muscle closing, especially for a variety of surgical diseases, has a good effect of lung and hemostasis, often used for lung disease and cough.
(9) 使药苦参： 味苦性寒， 有清热除湿， 解毒杀虫作用， 用于治疗痈 肿和湿疮疥廨等皮肤病， 以及肠中有风邪湿热引起的大便下血下
痢等症， 有解脸色发红、 麻风等病。 (9) Make the medicine Sophora: It is bitter cold, has heat and dehumidification, detoxifies and kills insects, is used to treat skin diseases such as bloated and wet sores, and the lower stools caused by wind and evil heat in the intestines. He has embolism, and has a complexion such as redness and leprosy.
中医诊治角度认为， 动物口蹄疫病属于温湿热毒引起， 本方各种中 草药均有清热解毒、 抗菌、 抗病毒、 消炎凉血作用。 According to the perspective of TCM diagnosis and treatment, animal foot and mouth disease is caused by warm and damp heat, and all kinds of Chinese herbal medicines have antipyretic, antibacterial, antiviral, anti-inflammatory and cooling effects.
本发明的治疗牧畜口蹄疫的中草药配方， 既能抗菌抗病毒又能治疗 局部溃烂病变，既能解毒清热消炎又能清除全身各种因口蹄疫病毒引起 的病状。本发明的中草药配方对治疗牧畜口蹄疫疗效显著， 起到标本兼 治内外综合疗效的作用。 与现有技术相比， 本发明中草药能缩短疗程 The Chinese herbal medicine formula for treating foot-and-mouth disease of animal husbandry of the invention can not only antibacterial, anti-viral but also treat local ulceration lesions, and can detoxify heat, reduce inflammation and remove all kinds of diseases caused by foot-and-mouth disease virus. The Chinese herbal medicine formula of the invention has remarkable curative effect on treating foot-and-mouth disease of animal husbandry, and plays a role in treating both internal and external comprehensive effects. Compared with the prior art, the Chinese herbal medicine of the invention can shorten the course of treatment
2/3, 防止并发症， 治愈率高， 死亡率低、 治愈率达 99%以上， 对未传 染的牲畜浸、喷本发明中草药的汤液能起到预防口蹄疫病发生的良好作 用。 2/3, prevention of complications, high cure rate, low mortality rate, cure rate of more than 99%, soaking unspoiled livestock and spraying the Chinese herbal medicine of the invention can prevent the occurrence of foot-and-mouth disease.
具体实施方式： detailed description:
本发明中草药配方的重量份数比如下： The parts by weight of the Chinese herbal medicine formula of the present invention are as follows:
半枝莲 100-130份、 蕺菜 (鱼腥草) 100-130份、 板蓝根 100-130份、 穿 心莲 100-130份、 黄芩 100-130份、 连翘 100-130份、 金银花 100-130份、 白芨 100-130份、 苦参 100-130份等组成。 100-130 parts of Scutellaria barbata L., 100-130 parts of leek (Houttuynia cordata), 100-130 parts of Radix isatidis, 100-130 parts of Andrographis paniculata, 100-130 parts of Astragalus, 100-130 parts of Forsythia, 100-130 parts of honeysuckle It consists of 100-130 parts of white peony and 100-130 parts of ginseng.
本发明实施例 1、 将半枝莲 110克、 蕺菜 (鱼腥草) 110克、 板蓝根 110 克、 穿心莲 110克、 黄芩 110克、 连翘 110克、 金银花 110克、 白芨 110 克、 苦参 110克九味干药， 加水 5000克熬制半小时， 将熬制的药液与药渣 分离， 得到 1000克药液。 使用时需先向药液中加入药液重量 100-150倍的
水进行稀释， 对牲畜的患病部位采用浸泡或喷涂的方法治疗 2分钟左右。 本发明实施例 2、半枝莲 130克、蕺菜 (鱼腥草) 130克、板蓝根 130克、 穿心莲 105克、 黄芩 120克、 连翘 110克、 金银花 120克、 白芨 115克、 苦参 120克九味干药。 其余步骤如上。 In the embodiment of the present invention, 110 grams of Scutellaria barbata L., 110 grams of leeks (Houttuynia cordata), 110 grams of Radix Isatidis, 110 grams of Andrographis paniculata, 110 grams of Astragalus, 110 grams of Forsythia, 110 grams of honeysuckle, 110 grams of white peony, Sophora flavescens 110 grams of nine-flavored dry medicine, add 5000 grams of water for half an hour, separate the tantalum liquid and the dregs to obtain 1000 grams of liquid. When using, you need to add 100-150 times the weight of the liquid to the liquid. The water is diluted, and the affected part of the animal is treated by soaking or spraying for about 2 minutes. Inventive Example 2, 130 grams of Scutellaria barbata, 130 grams of leeks (Houttuynia cordata), 130 grams of Radix Isatidis, 105 grams of Andrographis paniculata, 120 grams of Astragalus, 110 grams of Forsythia, 120 grams of honeysuckle, 115 grams of white peony, Kushen 120 Ke Jiuwei dry medicine. The remaining steps are as above.
按本发明实施例 1或 2的配方用量， 将上述九味药用水 5000克煎制半 小时， 得 1000克左右药液， 在该药液中加入 50000克左右的水进行稀释， 稀释后的药液可供 20至 30头猪羊浸脚两分钟左右， 之后可将使用过的药 液再重复使用， 让下一批的 20至 30头猪羊浸脚两分钟左右， 如此可累计 治疗或预防 100头猪羊以上。 采用本发明药液对猪羊浸脚， 病症不太严重 的浸脚一次后痊愈率可达 99°/。以上； 个别有并发肺炎的， 应兼打治疗肺炎 的针剂； 对于一些病症较为严重的经过每天浸脚一次， 两到三天后治愈率 即可达到 100%痊愈。 According to the dosage of the embodiment 1 or 2 of the present invention, the above-mentioned nine-flavor medicinal water 5000 g is fried for half an hour to obtain about 1000 g of the chemical liquid, and about 50,000 g of water is added to the liquid for dilution, and the diluted The liquid can be used for 20 to 30 pigs and sheep for about two minutes. After that, the used liquid can be reused, so that the next batch of 20 to 30 pigs can be soaked for about two minutes. Prevent more than 100 pigs and sheep. By using the liquid medicine of the present invention, the pigs are immersed in the feet, and the healing rate of the immersed feet which is not serious is up to 99°/. Above; individual patients with pneumonia should be treated with injections for pneumonia; for some patients with more serious illnesses, once every two to three days, the cure rate can reach 100%.
典型病例 1 : Typical case 1 :
1975年福州军区司令部农场有 300多头猪发生口蹄疫流行病， 病畜精 神不好、 体温升高、 流口水， 在蹄间表皮、 蹄冠鼻镜、 口腔黏膜和母畜的 乳房上长出水泡， 并且伴有胃肠道出血性炎症， 采用本发明实施例 2中草 药加水制成的药液对患病猪经药液浸脚一次后达到 95%痊愈， 个别经过两 次、三次浸脚后达到 100%痊愈； 有并发肺炎的、 除每天浸脚外， 还应打链 霉素才能够达到 100%治愈的目的。
典型病例 2: In 1975, more than 300 pigs in the Fuzhou Military Command headquarters had a foot-and-mouth disease epidemic. The sick animals were in poor spirits, their body temperature was rising, and they were drooling. They grew blisters on the hoof skin, the hoofed nose, the oral mucosa and the breasts of the dam. And accompanied by gastrointestinal hemorrhagic inflammation, the liquid medicine prepared by using the herbal medicine added with water in the second embodiment of the invention reaches 95% recovery after being immersed in the diseased pig once, and the individual reaches 100 after two or three times of immersion. % healed; with pneumonia, in addition to daily dip, streptomycin should be able to achieve 100% cure. Typical case 2:
1978年 5月， 福州仓山镇先锋村养猪场 50多头猪得了口蹄疫病， 症状 为精神不好， 体温高， 行走困难， 蹄部和鼻镜有水疱及糜烂， 采用本发明 实施例 1中草药加水制成的药液浸脚 1-2次后， 全部治愈。 In May 1978, more than 50 pigs in Pioneer Village, Cangshan Town, Fuzhou City, got foot and mouth disease. The symptoms were poor spirit, high body temperature, difficulty walking, blistering and erosion of hoof and nose, and the use of the herbal medicine of Example 1 of the present invention. After the medicinal solution prepared by adding water was immersed for 1-2 times, all were cured.
典型病例 3 : Typical case 3:
1981年 8月福州市闽侯县农场牛羊合计 100多头发生口蹄疫。 症状为 拒食、 体温高、 口腔、 舌、 咽喉、 蹄部、 乳房、 等出现不等水疱及溃烂， 胃肠出现血性的炎症， 采取本发明实施例 2药方剂对牛羊浸脚、 喷嘴一次， 治愈率达 97%; 个别病症较重的， 重复浸脚、 喷嘴一两次即可全部痊愈。
In August 1981, a total of more than 100 head and mouth diseases occurred in farms and cattle in Minhou County, Fuzhou. Symptoms include refusal to eat, high body temperature, blistering and ulceration in the mouth, tongue, throat, hoof, breast, etc., and bloody inflammation in the gastrointestinal tract. Take the prescription of the second embodiment of the present invention for the bovine sheep to soak the feet and the nozzle once. The cure rate is 97%; if the individual illness is heavier, repeat the dip and the nozzle can be cured one or two times.
Claims
1、 一种治疗牲畜口蹄疫的中草药， 其特征在于： 它是由下列重量份数 比的原料药制成， 半枝莲 100-130份、 鱼腥草 100-130份、 板蓝根 100-130 份、穿心莲 100-130份、黄芩 100-130份、连翘 100-130份、金银花 100-130 份、 白芨 100-130份、 苦参 100-130份。 1. A Chinese herbal medicine for treating foot-and-mouth disease of livestock, characterized in that it is made of the following raw materials of weight ratio, 100-130 parts of Scutellaria barbata, 100-130 parts of Houttuynia cordata, 100-130 parts of Radix isatidis, 100-130 parts of Andrographis paniculata, 100-130 parts of Astragalus, 100-130 parts of Forsythia, 100-130 parts of honeysuckle, 100-130 parts of white peony, 100-130 parts of Sophora flavescens.
2、 根据权利要求 1所述的治疗牲畜口蹄疫的中草药， 其特征在于： 它 是由下列重量份数比的原料药制成， 半枝莲 110份、 鱼腥草 110份、 板蓝 根 110份、 穿心莲 110份、 黄芩 110份、 连翘 110份、 金银花 110份、 白 芨 110份、 苦参 110份。 2. The Chinese herbal medicine for treating foot-and-mouth disease of livestock according to claim 1, characterized in that it is made of the following drug parts by weight ratio, 110 parts of Scutellaria barbata, 110 parts of Houttuynia cordata, 110 parts of Radix isatidis, and Andrographis paniculata 110 parts, 110 parts of Astragalus, 110 pieces of Forsythia, 110 parts of honeysuckle, 110 parts of white peony, 110 parts of Sophora flavescens.
3、 根据权利要求 1所述的治疗牲畜口蹄疫的中草药， 其特征在于： 它 是由下列重量份数比的原料药制成， 半枝莲 130克、 鱼腥草 130克、 板蓝 根 130克、 穿心莲 105克、 黄芩 120克、 连翘 110克、 金银花 120克、 白 芨 115克、 苦参 120克。
3. The Chinese herbal medicine for treating foot-and-mouth disease of livestock according to claim 1, characterized in that it is made of the following drug parts by weight ratio, 130 g of Scutellaria barbata, 130 g of Houttuynia cordata, 130 g of Radix Isatidis, and Andrographis paniculata 105 grams, 120 grams of astragalus, 110 grams of forsythia, 120 grams of honeysuckle, 115 grams of white peony, 120 grams of Sophora.
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| CN200810071392.5 | 2008-07-14 | ||
| CN2008100713925A CN101306164B (en) | 2008-07-14 | 2008-07-14 | Chinese herbal medicine for treating livestock foot-and-mouth disease |
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| WO2020237284A1 (en) * | 2019-05-28 | 2020-12-03 | Animal Ethics Pty Ltd | Method of disease control |
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| CN104826039A (en) * | 2015-04-20 | 2015-08-12 | 唐兴龙 | Externally applied medicine for treating swine foot and mouth disease |
| CN104825887A (en) * | 2015-05-18 | 2015-08-12 | 山东新希望六和集团有限公司 | Medicament composition for preventing and treating bovine foot and mouth disease and preparation method of medicament composition |
| CN116036195A (en) * | 2023-01-07 | 2023-05-02 | 元亨生物技术有限公司 | A Chinese medicinal unguent for treating foot and mouth disease of livestock, and its preparation method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1442163A (en) * | 2002-12-31 | 2003-09-17 | 尚馨室 | Chinese medicine formula for treating livestock foot and mouth disease |
| CN1569128A (en) * | 2004-04-23 | 2005-01-26 | 赵子群 | Livestock feedstuff addictive with Chinese medicine for preventing and treating aftosa and its preparation |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1442163A (en) * | 2002-12-31 | 2003-09-17 | 尚馨室 | Chinese medicine formula for treating livestock foot and mouth disease |
| CN1569128A (en) * | 2004-04-23 | 2005-01-26 | 赵子群 | Livestock feedstuff addictive with Chinese medicine for preventing and treating aftosa and its preparation |
Non-Patent Citations (2)
| Title |
|---|
| FU, WENGUI ET AL.: "The Diagnosis and Prevention Method of Pig's Foot and Mouth Disease", LIVESTOCK AND POULTRY INDUSTRY, vol. 227, March 2008 (2008-03-01), pages 30 - 31 * |
| XING, DIANQUAN ET AL.: "The Treatment and Prevention of Livestock's Foot and Mouth Disease", APPLICABLE TECHNOLOGIE.S FOR RURAL AREAS, no. 4, 2002, pages 42 - 43 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020237284A1 (en) * | 2019-05-28 | 2020-12-03 | Animal Ethics Pty Ltd | Method of disease control |
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| CN101306164A (en) | 2008-11-19 |
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