WO2009154377A3 - Real-time continuous detection device - Google Patents

Real-time continuous detection device Download PDF

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Publication number
WO2009154377A3
WO2009154377A3 PCT/KR2009/003174 KR2009003174W WO2009154377A3 WO 2009154377 A3 WO2009154377 A3 WO 2009154377A3 KR 2009003174 W KR2009003174 W KR 2009003174W WO 2009154377 A3 WO2009154377 A3 WO 2009154377A3
Authority
WO
WIPO (PCT)
Prior art keywords
real
sample
detection device
recognising
capturing
Prior art date
Application number
PCT/KR2009/003174
Other languages
French (fr)
Korean (ko)
Other versions
WO2009154377A2 (en
Inventor
백세환
조현규
Original Assignee
고려대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 고려대학교 산학협력단 filed Critical 고려대학교 산학협력단
Priority to US12/999,979 priority Critical patent/US20110097740A1/en
Priority to CN2009801232997A priority patent/CN102105798A/en
Priority to JP2011514486A priority patent/JP2011524982A/en
Publication of WO2009154377A2 publication Critical patent/WO2009154377A2/en
Publication of WO2009154377A3 publication Critical patent/WO2009154377A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers

Abstract

The present invention relates to a real-time detection device containing a sample introduction channel, a sample analysis site and a sample discharge channel, wherein the sample analysis site comprises a reversibly reactive capturing and recognising component and a sensor for sensing signals generated from a combination of a capturing and recognising component and an analyte in a sample. The present invention can measure, in real time, changes in the concentration of the analyte by continuously reusing a set amount of the reversibly reactive capturing and recognising component. The real-time continuous detection device of the present invention can be employed in the medical, public health, defence, environment, food, veterinary and biotechnology industries since it can be used to detect or analyse, by way of example, biological metabolites, proteins, hormones, nucleic acids, cells, food substances to be examined, environmentally hazardous substances or chemical, biological and radiological military substances to be measured.
PCT/KR2009/003174 2008-06-18 2009-06-12 Real-time continuous detection device WO2009154377A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/999,979 US20110097740A1 (en) 2008-06-18 2009-06-12 Real-time continuous detection device
CN2009801232997A CN102105798A (en) 2008-06-18 2009-06-12 Real-time continuous detection device
JP2011514486A JP2011524982A (en) 2008-06-18 2009-06-12 Real-time continuous detector

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020080057532A KR100958198B1 (en) 2008-06-18 2008-06-18 Real-time detection devices by continuous monitoring
KR10-2008-0057532 2008-06-18

Publications (2)

Publication Number Publication Date
WO2009154377A2 WO2009154377A2 (en) 2009-12-23
WO2009154377A3 true WO2009154377A3 (en) 2010-03-18

Family

ID=41434538

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/003174 WO2009154377A2 (en) 2008-06-18 2009-06-12 Real-time continuous detection device

Country Status (5)

Country Link
US (1) US20110097740A1 (en)
JP (1) JP2011524982A (en)
KR (1) KR100958198B1 (en)
CN (1) CN102105798A (en)
WO (1) WO2009154377A2 (en)

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FR2959568A1 (en) * 2010-04-28 2011-11-04 Commissariat Energie Atomique METHOD AND DEVICE FOR DETECTING AND QUANTIFYING AN ANALYTE WITH RECYCLING OF REAGENTS
KR101145668B1 (en) * 2010-11-22 2012-05-24 전자부품연구원 The continuous glucose monitoring system
EP2506014B1 (en) * 2011-03-30 2014-08-06 Kabushiki Kaisha Toshiba Measuring system using optical waveguide, measuring device, measuring method, optical waveguide type sensor chip, and magnetic fine particle
KR101342755B1 (en) 2011-10-26 2013-12-19 고려대학교 산학협력단 Immature antibody, continuous detection apparatus using the same and method for real-time continuous detection
EP2910947B1 (en) 2012-10-18 2019-02-13 Konica Minolta, Inc. Assay method using surface plasmon-field enhanced fluorescence spectroscopy
KR101568573B1 (en) 2013-03-13 2015-11-20 고려대학교 산학협력단 Apparatus and method for detection and enumeration of rare cells in whole blood
WO2014142559A1 (en) * 2013-03-13 2014-09-18 고려대학교 산학협력단 Apparatus and method for detecting and counting rare cells in blood
JP2014215282A (en) * 2013-04-30 2014-11-17 日本精工株式会社 Target substance detection device and target substance detection method
KR101482624B1 (en) * 2013-05-16 2015-01-19 한국과학기술연구원 Continuous monitoring system and method for target water pollutants
DE102013011304A1 (en) * 2013-07-02 2015-01-22 Technische Universität Dresden Method and device for detecting binding events of molecules
KR101865428B1 (en) * 2013-12-20 2018-06-07 연세대학교 산학협력단 Method for measuring biomolecule using localized surface plasmon resonance
KR101629848B1 (en) * 2014-11-18 2016-06-14 가천대학교 산학협력단 Method for reproducing sensor head of biosensor
JP6796857B2 (en) * 2017-02-27 2020-12-09 国立研究開発法人物質・材料研究機構 Sample identification method and equipment using chemical sensors
KR102151146B1 (en) 2018-07-27 2020-09-02 상명대학교 천안산학협력단 Method for reusing single-walled carbon nanotube-based biosensor
US20220088596A1 (en) * 2019-01-11 2022-03-24 University Of Cincinnati Membrane-coupled continuous sensing systems

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Publication number Priority date Publication date Assignee Title
KR20050058154A (en) * 2003-12-11 2005-06-16 한국생명공학연구원 Measuring method of biochip and biosensor using surface plasmon resonance combined with an enzymatic precipitation
KR100673835B1 (en) * 2005-08-16 2007-01-24 성균관대학교산학협력단 Method for assaying protein using surface plasmon resonance
KR100737689B1 (en) * 2006-08-23 2007-07-09 성균관대학교산학협력단 A method for amplication of signals of surface plasmon resonance sensor
KR100775334B1 (en) * 2006-11-08 2007-11-09 성균관대학교산학협력단 Method of real time detection of pathogenic microorganism using the competitive immunoreaction-mediated flow type surface plasmon resonance biosensor

Also Published As

Publication number Publication date
US20110097740A1 (en) 2011-04-28
JP2011524982A (en) 2011-09-08
KR20090131588A (en) 2009-12-29
KR100958198B1 (en) 2010-05-14
CN102105798A (en) 2011-06-22
WO2009154377A2 (en) 2009-12-23

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