WO2009107959A3 - 상동나무 지상부로부터 유용 플라보노이드 다량 함유 획분과 신규 플라보노이드 물질의 분리 방법 - Google Patents

상동나무 지상부로부터 유용 플라보노이드 다량 함유 획분과 신규 플라보노이드 물질의 분리 방법 Download PDF

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Publication number
WO2009107959A3
WO2009107959A3 PCT/KR2009/000862 KR2009000862W WO2009107959A3 WO 2009107959 A3 WO2009107959 A3 WO 2009107959A3 KR 2009000862 W KR2009000862 W KR 2009000862W WO 2009107959 A3 WO2009107959 A3 WO 2009107959A3
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WO
WIPO (PCT)
Prior art keywords
flavonoid
ground part
novel
tree named
containing fraction
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PCT/KR2009/000862
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English (en)
French (fr)
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WO2009107959A2 (ko
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정신교
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경북대학교산학협력단
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Priority to CN200980107000.9A priority Critical patent/CN102137661B/zh
Publication of WO2009107959A2 publication Critical patent/WO2009107959A2/ko
Publication of WO2009107959A3 publication Critical patent/WO2009107959A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

본 발명은 플라보노이드 물질을 분리하는 방법에 있어서: 상동나무 지상부를 건조하고 세절하여 볶고, 클로로포름으로 탈지 후 다시 60% 아세톤 수용액으로 조추출하는 제1단계(S10); 상기 제1단계(S10)에서 추출된 아세톤 조추출 엑기스를 다시 헥산, 에틸아세테이트, 부탄올, 물로 용매 분별하는 제2단계(S20); 및 상기 제2단계(S20)에서 분별된 엑기스 중 에틸아세테이트 획분을 용출시켜서 얻은 획분을 박층 크로마토그라피(Thin layer chromatography, TLC)로 조사하면서 신규성 플라보노이드(flavonoid)인 7-O-메틸메란시트린(7-O-methyl mearnsitrin)을 얻는 제3단계(S30);를 포함하여 이루어지는 것을 특징으로 한다. 이에 따라, 식품첨가물, 건강기능성 식품, 순환기 계통 질병 예방 및 치료, 기타 의약품의 주ㆍ부 원료로 활용되어 국내의 자생식물의 고부가가치 소재 개발과 관련 산업의 활성화를 도모할 수 있다.
PCT/KR2009/000862 2008-02-25 2009-02-24 상동나무 지상부로부터 유용 플라보노이드 다량 함유 획분과 신규 플라보노이드 물질의 분리 방법 WO2009107959A2 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN200980107000.9A CN102137661B (zh) 2008-02-25 2009-02-24 从雀梅树枝干中分离类黄酮的方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0016954 2008-02-25
KR1020080016954A KR100969134B1 (ko) 2008-02-25 2008-02-25 상동나무 지상부로부터 유용 플라보노이드 다량 함유획분과 신규 플라보노이드 물질의 분리 방법

Publications (2)

Publication Number Publication Date
WO2009107959A2 WO2009107959A2 (ko) 2009-09-03
WO2009107959A3 true WO2009107959A3 (ko) 2009-12-10

Family

ID=41016575

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/000862 WO2009107959A2 (ko) 2008-02-25 2009-02-24 상동나무 지상부로부터 유용 플라보노이드 다량 함유 획분과 신규 플라보노이드 물질의 분리 방법

Country Status (3)

Country Link
KR (1) KR100969134B1 (ko)
CN (1) CN102137661B (ko)
WO (1) WO2009107959A2 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101429534B1 (ko) * 2012-10-30 2014-08-12 한불화장품주식회사 매발톱나무 추출물을 함유하는 화장료 조성물
KR101716489B1 (ko) * 2016-10-07 2017-03-27 주식회사 아미코스메틱 상동나무 추출물을 함유하는 화장료 조성물
KR101854446B1 (ko) * 2017-01-10 2018-06-14 주식회사 아미코스메틱 상동나무 추출물과 미세침을 함유하는 화장료 조성물
KR102171209B1 (ko) 2019-05-10 2020-10-28 안동대학교 산학협력단 상동나무 추출물을 유효성분으로 함유하는 혈전증의 예방 또는 치료용 약학적 조성물 및 건강 기능 식품
KR20200131008A (ko) 2019-05-13 2020-11-23 대한민국(산림청 국립산림과학원장) 상동나무 추출물을 포함하는 항염증 조성물

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BURGHARDT, F. ET AL.: "Uptake of Flavonoids from Vicia villosa (Fabaceae) by the Lycaenid Butterfly, Polyommatus icarus (Lepidoptera: Lycaenidae)", BIOCHEMICAL SYSTEMATICS AND ECOLOGY, vol. 25, no. 6, 1997, pages 527 - 536 *
CHUNG, SHIN KYO ET AL.: "Novel Flavonol Glycoside, 7-O-Methyl Mearnsitrin, from Sageretia theezans and Its Antioxidant Effect", J. AGRIC. FOOD CHEM., vol. 52, 2004, pages 4664 - 4668 *
RODRIGUES, J. ET AL.: "An unusual C6.C600 linked flavonoid from Miconia cabucu (Melastomataceae)", PHYTOCHEMISTY, vol. 68, 2007, pages 1781 - 1784 *

Also Published As

Publication number Publication date
WO2009107959A2 (ko) 2009-09-03
KR100969134B1 (ko) 2010-07-08
CN102137661A (zh) 2011-07-27
KR20090091594A (ko) 2009-08-28
CN102137661B (zh) 2016-04-20

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