WO2009084974A8 - 1,3- диалкилбензимидазолия галогениды, обладающие регенерационной, противовоспалительной и противомикробной активностью - Google Patents

1,3- диалкилбензимидазолия галогениды, обладающие регенерационной, противовоспалительной и противомикробной активностью Download PDF

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Publication number
WO2009084974A8
WO2009084974A8 PCT/RU2007/000744 RU2007000744W WO2009084974A8 WO 2009084974 A8 WO2009084974 A8 WO 2009084974A8 RU 2007000744 W RU2007000744 W RU 2007000744W WO 2009084974 A8 WO2009084974 A8 WO 2009084974A8
Authority
WO
WIPO (PCT)
Prior art keywords
halogenides
benzimidazole
dialkyl
inflammatory
antimicrobial activity
Prior art date
Application number
PCT/RU2007/000744
Other languages
English (en)
French (fr)
Other versions
WO2009084974A1 (en
Inventor
Борис Витальевич СТРАДОМСКИЙ
Original Assignee
АВЕРИН, Константин Михайлович
СОЛОДУНОВ, Юрий Юрьевич
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by АВЕРИН, Константин Михайлович, СОЛОДУНОВ, Юрий Юрьевич filed Critical АВЕРИН, Константин Михайлович
Priority to US12/735,253 priority Critical patent/US20100286406A1/en
Priority to JP2010540612A priority patent/JP2011507953A/ja
Priority to EP07866968A priority patent/EP2230233A4/en
Priority to PCT/RU2007/000744 priority patent/WO2009084974A1/ru
Priority to CN200780102059XA priority patent/CN101910137A/zh
Publication of WO2009084974A1 publication Critical patent/WO2009084974A1/ru
Publication of WO2009084974A8 publication Critical patent/WO2009084974A8/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретение относится к области медицины, ветеринарии и косметологии, в частности к средствам, используемым для ускорения процессов регенерации тканей, особенно при наличии воспалительных процессов, сопровождаемых заражением патогенной микрофлорой, и может быть использовано в фармацевтической и косметологической промышленности. Предложены галогениды 1,3-диaлкилбeнзимидaзoлия, обладающие регенерационной, противовоспалительной и противомикробной активностью, общей формулы: где R1, R2 = Alk, X-= F-, Cl-, Br-, J-
PCT/RU2007/000744 2007-12-27 2007-12-27 1,3-dialkyl-benzimidazole halogenides exhibiting regeneration, anti-inflammatory and antimicrobial activity WO2009084974A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US12/735,253 US20100286406A1 (en) 2007-12-27 2007-12-27 1,3- dialkylbenzimidazole halogenides exhibiting regenerative, anti-inflammatory, and antimicrobial activity
JP2010540612A JP2011507953A (ja) 2007-12-27 2007-12-27 再生促進活性、抗炎症活性、及び抗菌活性を示すハロゲン化１，３−ジアルキルベンゾイミダゾール
EP07866968A EP2230233A4 (en) 2007-12-27 2007-12-27 HALIDES OF 1,3-DIALKYL-BENZIMIDAZOLE HAVING REGENERATIVE, ANTI-INFLAMMATORY AND ANTI-BACTERIAL ACTIVITY
PCT/RU2007/000744 WO2009084974A1 (en) 2007-12-27 2007-12-27 1,3-dialkyl-benzimidazole halogenides exhibiting regeneration, anti-inflammatory and antimicrobial activity
CN200780102059XA CN101910137A (zh) 2007-12-27 2007-12-27 显示出再生活性、消炎活性和抗微生物活性的1,3-二烷基苯并咪唑卤化物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/RU2007/000744 WO2009084974A1 (en) 2007-12-27 2007-12-27 1,3-dialkyl-benzimidazole halogenides exhibiting regeneration, anti-inflammatory and antimicrobial activity

Publications (2)

Publication Number Publication Date
WO2009084974A1 WO2009084974A1 (en) 2009-07-09
WO2009084974A8 true WO2009084974A8 (ru) 2009-10-22

Family

ID=40824535

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU2007/000744 WO2009084974A1 (en) 2007-12-27 2007-12-27 1,3-dialkyl-benzimidazole halogenides exhibiting regeneration, anti-inflammatory and antimicrobial activity

Country Status (5)

Country Link
US (1) US20100286406A1 (ru)
EP (1) EP2230233A4 (ru)
JP (1) JP2011507953A (ru)
CN (1) CN101910137A (ru)
WO (1) WO2009084974A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014043246A1 (en) * 2012-09-11 2014-03-20 The Board Of Trustees Of The University Of Illinois Enoyl reductase inhibitors with antibacterial activity

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1161725B (de) * 1959-10-10 1964-01-23 Bayer Ag Fungizides Pflanzenschutzmittel
DE1287585B (de) * 1963-12-13 1969-01-23 Hoechst Ag Verfahren zur Herstellung von Benzimidazoliumverbindungen
US3879414A (en) * 1973-06-21 1975-04-22 Squibb & Sons Inc Enol betaines of benzimidazoles
RU2033164C1 (ru) * 1992-01-10 1995-04-20 Ливицкий Василий Иванович Антимикробный лечебный препарат
RU2009132C1 (ru) * 1992-04-22 1994-03-15 Северо-Кавказский зональный научно-исследовательский ветеринарный институт Периодиды бензимидазолия, обладающие антимикробным действием
RU2135476C1 (ru) * 1998-12-07 1999-08-27 Ливицкий Василий Иванович Дийодбромиды 1,2,3-замещенных бензимидазолия и их водорастворимая композиция
RU2148578C1 (ru) * 1999-04-20 2000-05-10 Ливицкий Василий Иванович Дийодидхлориды 1,2,3-замещенного бензимидазолия и их водорастворимая композиция

Also Published As

Publication number Publication date
WO2009084974A1 (en) 2009-07-09
CN101910137A (zh) 2010-12-08
US20100286406A1 (en) 2010-11-11
EP2230233A4 (en) 2011-06-08
JP2011507953A (ja) 2011-03-10
EP2230233A1 (en) 2010-09-22

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