WO2009083736A1 - Compositions et leurs utilisations - Google Patents

Compositions et leurs utilisations Download PDF

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Publication number
WO2009083736A1
WO2009083736A1 PCT/GB2008/051228 GB2008051228W WO2009083736A1 WO 2009083736 A1 WO2009083736 A1 WO 2009083736A1 GB 2008051228 W GB2008051228 W GB 2008051228W WO 2009083736 A1 WO2009083736 A1 WO 2009083736A1
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WIPO (PCT)
Prior art keywords
composition
ester
esters
optionally substituted
aromatic acid
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Application number
PCT/GB2008/051228
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English (en)
Inventor
Samad Syed
Phillip Cotrell
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Innospec Limited
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Publication of WO2009083736A1 publication Critical patent/WO2009083736A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/20—Organic compounds containing oxygen
    • C11D3/2093—Esters; Carbonates

Definitions

  • This invention relates to aromatic esters (for example benzoate esters) of C12 and Ci 4 fatty alcohols, to their use in cosmetic compositions, and to additive compositions containing them in admixture.
  • aromatic esters for example benzoate esters
  • esters composed mainly or essentially of components within the mixtures described in US 4,275,222, when added to a cosmetic composition, particularly a sunscreen composition, provide new and beneficial properties.
  • an additive composition for enhancing a cosmetic composition comprising in admixture (a) an ester of an optionally substituted aromatic acid and a C12 primary alcohol and (b) an ester of an optionally substituted aromatic acid and a Ci 4 primary alcohol, wherein compounds (a) and (b) together provide at least 60% by weight, of the additive composition .
  • a preferred ester (a) is an ester of an optionally substituted benzoic acid and a branched C12 primary alcohol .
  • a preferred ester (b) is an ester of an optionally substituted benzoic acid and a branched Ci 4 primary alcohol .
  • Q is a substituent, as later defined; m is 0 (zero) or an integer from 1 to 5 (the groups Q being the same as or different from each other when m is 2, 3, 4 or 5) ; and where R is a Ci 2 alkyl group in compound (a) , or a C i4 alkyl group in compound (b) .
  • the benzene ring (or other aromatic ring system) of ester (a) or (b) may be substituted with 0 to 5 groups (in addition to the reacted acid group COOH) .
  • it may be tri- or di-substituted in the ring (or ring system) or, more preferably, mono-substituted. Substitution may be at the ortho, and/or meta, and/or para position(s).
  • the benzene ring (or other aromatic ring) of ester (a) may be substituted and the benzene ring (or other aromatic ring system) of ester (b) may be unsubstituted; or the benzene ring (or other aromatic ring system) of ester (b) may be substituted and the benzene ring (or other aromatic ring system) of ester (a) may be unsubstituted; or both may be substituted, differently or the same; or, most preferably, both may be unsubstituted.
  • the or each substituent of the benzene ring (or other aromatic ring system) of ester (a) or (b) may be any common group used for substitution of a benzene ring (or other aromatic ring system) , for example one or more of an alkyl group (an especially preferred substituent), an alkenyl group, a haloalkyl group, an alkynyl group, a nitrile group, a carboxylic acid (in addition to the reacted carboxylic acid group) , an ester, an ether, an alkoxy group, a haloalkoxy group, a halo group, a hydroxyl group, a mercapto group, an alkylmercapto group, an alkylsulfoxy group, a sulfoxy group, an aryl group, an arylalkyl group, a substituted or unsubstituted amine group or a nitro group.
  • an alkyl group an especially preferred substituent
  • an alkyl group including of the alkyl moiety of an alkyl- containing group (for example alkoxy or haloalkyl) is suitably a Ci_ 4 alkyl group, more preferably a methyl group.
  • a Ci_ 4 alkyl group more preferably a methyl group.
  • each ester (a) and (b) may be branched at one or more positions of the backbone of the primary alcohol. Preferably, however, each backbone is linear.
  • the primary alcohol backbone of each ester (a) and (b) may be unsaturated or it may be saturated.
  • esters (a) and (b) of the first aspect of the invention together provide at least 70% by weight of the additive composition, more preferably at least 80%, more preferably at least 90%, more preferably at least 95%. Most preferably they provide at least 98% by weight of the additive composition.
  • the additive composition consists essentially of the esters (a) and (b) .
  • the ratio by weight of ester (a) to ester (b) is at least 1:1.
  • ester (a) is present in weight excess, over ester (b) .
  • the ratio by weight of ester (a) to ester (b) is at least 1.5:1, most preferably at least 2:1.
  • the ratio by weight of ester (a) to ester (b) is up to 5:1, more preferably up to 4:1, and most preferably up to 3:1.
  • An especially preferred ratio is 2 to 2.75 parts by weight of ester (a) to 1 part by weight of ester (b) .
  • the additive composition of the invention can produce enhanced properties when added to cosmetic compositions. These enhanced properties make such additive compositions beneficial for use in cosmetic products such as skin care, topical and personal care products. These products may be in the form of a cream, lotion, bar or stick.
  • the additive compositions of the invention have new and unexpected properties as cosmetic additives not only as an emollient but also as solvents and liquid carriers for a cosmetically active material in the cosmetic preparation.
  • the ester mixture of the first aspect or used in the second aspect may be made, separately or together, by analogous esterification reactions to those used for the preparation of other fatty alcohol-aromatic acid esters.
  • a composition for application to the person comprising (a) an ester of an optionally substituted aromatic acid and a Ci 2 primary alcohol and (b) an ester of an optionally substituted aromatic acid and a Ci 4 primary alcohol.
  • Said composition may also be called herein a cosmetic composition or a topical composition or a skin benefit composition.
  • a cosmetic composition of the second aspect has ester (a) to ester (b) present in a weight ratio which is as defined above for the additive composition of the first aspect.
  • the esters (a) and (b) may have been introduced separately into the cosmetic composition.
  • esters (a) and (b) in the form of an additive composition of the first aspect may be introduced to other ingredients to form a composition of the second aspect, but the invention as defined in the second aspect is not limited in that way.
  • compositions of the second aspect of the invention may comprise a carrier or diluent or solvent; and/or a cosmetically effective ingredient. Such further components may be as hereinafter described.
  • esters (a) and (b) of a composition of the second aspect of the invention constitute at least 40 %wt, preferably at least 50 %wt, more preferably at least 70 %wt, most preferably at least 90 %wt, of the total weight of C12-C15 fatty alcohol-aromatic acid (ester) content in the cosmetic composition.
  • the cosmetic composition is substantially free of C12-C15 fatty alcohol- aromatic acid esters apart from compounds (a) and (b) .
  • Esters (a) and (b) of a composition of the second aspect of the invention may suitably constitute at least 40 %wt, preferably at least 50 %wt, more preferably at least 70 %wt, most preferably at least 90 %wt, of the total weight of all esters of fatty alcohols and acids in the composition. Most preferably the composition is substantially free of all esters of fatty alcohols and acids apart from the esters (a) and (b) .
  • the ester mixture of the first aspect may impart valuable properties to the composition of the second aspect.
  • the esters (a) and (b) in admixture are substantially non- greasy, show lack of oiliness and greasiness, have very low cloud point and pour point, have a bland odor, low toxicity and are stable.
  • the esters (a) and (b) in admixture have good tactile properties, spreadability, solubility in/with sunscreen agents, low tackiness (stickiness), low greasiness on the skin, good suspension properties (e.g. TiC>2) and are effective in wetting and dispersing pigments.
  • the esters (a) and (b) have properties in addition to those mentioned hereinbefore when used as an emollient in a sunscreen agent.
  • SPDF sun protection factor
  • sunscreen agents of a lower sun protecting factor can be utilized in sunscreen compositions containing the esters (a) and (b) achieve the sunscreen protecting factors of higher protecting sunscreen agents.
  • esters (a) and (b) should be added to a composition when it is substantially pure and substantially free of other esters of aromatic acids and fatty alcohols. In this manner, it is believed that best results are achieved. However, this should not preclude the use of other fatty acid esters or fatty acids in these compositions, suitably within the percentage limits mentioned above, since the use of the esters (a) and (b) may still provide enhanced results to cosmetic compositions in which they are incorporated.
  • the esters (a) and (b) may be incorporated into cosmetic compositions as an emollient in order to impart to these compositions the aforementioned beneficial properties of this invention.
  • the esters (a) and (b) whether added individually or together in the form of an additive composition of the first aspect, can be used as an ingredient for any topical or cosmetic compositions including skin, nail, lip, hair topical compositions not only as an emollient but as a diluent, solvent and liquid carrier.
  • the esters (a) and (b) function as an effective solubilizer for the cosmetically active agents used in these cosmetic compositions.
  • the esters (a) and (b) are suitably incorporated in a cosmetic composition in an emollient effective amount.
  • the esters (a) and (b) are provided in an amount at least sufficient to provide the emollient properties to the cosmetic composition.
  • Emollients are dermatologically acceptable compositions that tend to lubricate the skin, increase the softness and suppleness of the skin, prevent or relieve dryness of the skin and/or protect the skin.
  • These emollients are typically water emissible, oily or waxy materials and in order to provide the improved results of this invention, the esters (a) and (b) are employed in any amount sufficient to impart, or improve to any degree, emolliency to the cosmetic composition.
  • the amount of the esters (a) and (b) in these cosmetic compositions depends on the type and quantity of other ingredients used and in the amount and type of functional additives that are utilized. Generally the amount of the esters (a) and (b) that are incorporated into these cosmetic compositions ranges from about 0.1% to about 30% by weight, for example about 0.3% to about 20% by weight, based upon the total weight of the cosmetic composition, with amounts from about 5% to about 15% by weight based upon the total weight of the cosmetic composition being especially preferred.
  • a third aspect of the present invention there is provided a method of preparing a cosmetic composition, wherein the esters (a) and (b) , separately or together in an additive composition of the first aspect, are mixed with other ingredient so as to produce a composition of the second aspect of this invention.
  • esters (a) and (b) can be utilized to produce the beneficial properties set forth above in any conventional topical cosmetic composition such sunscreen creams, hair creams, hand ointments, lipsticks, skin lotions and creams as well as other formulations.
  • cosmetic compositions include cosmetic, personal cleansing and skin care compositions, and include hair and nail compositions which are topically applied to the humans to achieve a beneficial action on the surface to which it is applied.
  • the esters (a) and (b) are advantageous in that they may be one or more of non-oily, tasteless, inert, essentially non-toxic and non sensitizing, and stable. They are useful as one or more of emollient, solubilizer, moisturizer, plasticizer, sunscreen vehicle/solvent, de-oiler/ degreaser and emulsifier/co-emulsifier .
  • the esters (a) and (b) possess unusual physico-chemical properties, in particular, excellent spreading coefficient which can make it beneficial and unique component of sophisticated delivery system such as in hand, face, and body creams, lotions, soaps and sticks.
  • esters (a) and (b) may be a solvent and/or vehicle for solid organic ultraviolet (UV) absorbers. They may have a function as a plasticizer for polymers contained in skin care composition, and may act as an auxiliary suspending agent capable of assisting in the suspension of ingredients in skincare composition and also may function as a dye levelling agent and/or dye carrier. Thus, the esters (a) and (b) when used in a skin care (or other cosmetic) composition may serve not only as an emollient, but also as a carrier; and it may also exhibit these other functions.
  • UV solid organic ultraviolet
  • the cosmetic composition whose properties may be enhanced by the addition of the esters (a) and (b) can be any conventional cosmetically active material which provides a therapeutic or beneficial cosmetic action to the human body particularly the skin, lips hair or nails.
  • the cosmetic composition can be in the form of a cream, lotion, ointment, spray, soap-bar, stick etc, which contain a cosmetically active material.
  • the term cosmetically active materials may include anti-aging ingredients, anti-wrinkling agents, minerals, preservatives, antioxidants, moisturizers, vitamins, sunscreen agents, and anti-acne agents, deodorants, antiperspirants, etc.
  • the preferred cosmetically active material are vitamins such as Vitamin A, B 1 , B 2 , B 3 , B 5 , B 6 , B 12 , biotin, Vitamin C, Vitamin D, Vitamin E, folic acid and Vitamin K.
  • Other preferred cosmetically active ingredients which can be utilized in the cosmetic composition of this invention include anti- wrinkling agents, anti-acne agents, moisturizers such as Vitamin E, mineral oils and diisopropyl adipate.
  • the cosmetic composition may contain a liquid aqueous carrier medium for the cosmetic composition.
  • the liquid aqueous carrier medium can be water or it can be an oil in water or oil in water liquid emulsion.
  • any cosmetically acceptable carrier which is compatible with the water can be combined with water to form the aqueous carrier medium of the second component system.
  • the aqueous carrier medium can contain one or more oil components.
  • the oil component may be any pharmaceutically or cosmetically acceptable oily material which is substantially insoluble in water. These materials can be found for example in the CTFA International Dictionary of Cosmetic Ingredients as well as the U.S. Pharmacopoeia or other equivalent sources.
  • Suitable oil components include, but are not limited to, natural oils, such as coconut oil; hydrocarbons, such as mineral oil and hydrogenated polyisobutene; sterol derivatives, such as lanolin; animal waxes, such as beeswax, plant waxes, such as carnauba; mineral waxes, such as ozokerite; petroleum waxes, such as paraffin wax; synthetic waxes, such as polyethylene; and mixtures thereof.
  • natural oils such as coconut oil
  • hydrocarbons such as mineral oil and hydrogenated polyisobutene
  • sterol derivatives such as lanolin
  • animal waxes such as beeswax, plant waxes, such as carnauba
  • mineral waxes such as ozokerite
  • petroleum waxes such as paraffin wax
  • synthetic waxes such as polyethylene
  • any conventional solid carrier medium used to formulate such solid cosmetic compositions can be used in accordance with this invention .
  • the cosmetic composition of the second aspect may contain in addition stable ingredients which include various antioxidants, stabilizers, moisturizers, preservatives and emulsifiers such as those mentioned hereinbefore. Any conventional antioxidant, moisturizer, stabilizer, preservative, or emulsifier which is stable in the carrier medium can be present.
  • Emulsifiers such as glycerol stearate or methyl glucose sesquistearate may also be present
  • organic solvents such as lower aliphatic alcohols from 1 to 6 carbon atoms, such as ethanol isopropanol or propanol, or glycols such as glycerin or 1, 2-propylene glycol.
  • perfume oils such as ethylene glycol distearate; wetting agents or emulsifiers; anti-bacterial and fungicidal ingredients; thickeners (such as bentonite) ; pH buffer substances; moisture retaining agents; fragrances or perfumes; perfume oils; colorants (such as natural or synthetic direct dyes but also tinting agents such as fluorescein sodium salt); sunscreens or UV filters; preservatives; antioxidants (such as tocopherols); pyrogemic silicic acid; complexing agents; and also physiologically tolerable inorganic or organic acids, such as phosphoric acid, acetic acid, formic acid, glyoxylic acid, lactic acid, tartaric acid or citric acid; bases; salts (such as sodium chloride); buffers (such as sodium citrate or sodium phosphate); consistency-lending agents; and natural, modified, partly or entirely synthetic polymers (such as chitosan, FMOC chitosan and P
  • these cosmetic compositions do not contain fatty alcohol esters, other than those of the esters (a) and (b) ; or if present such further esters are preferably present within limits set out hereinabove.
  • a method of treating the skin or hair of a person using (a) an ester of an optionally substituted aromatic acid and a C12 primary alcohol and (b) an ester of an optionally substituted aromatic acid and a Ci 4 primary alcohol.
  • Preferred features of the first and second aspects are also preferred features of the third, fourth or fifth aspects.
  • Additive Mixture A is a mixture of Ci 2 and Ci 4 benzoate esters prepared by esterifying approximately 1 mole of a mixture of C 12 and C i4 fatty alcohols sold under the trade name "C12-C14 Midcut Fatty Alcohol” by Procter and Gamble. This is a pure mixture of alcohols specifically composed of approximately 70% by weight of n- dodecanol and 30% by weight of n-tetradecanol, with 1 mole of benzoic acid (i.e. unsubstituted) under standard esterification conditions. The resulting product had an acid value below 0.1 mg KOH/g and had been filtered through a filter press with Whatman Paper No. 4. Additive Mixture A was an odourless liquid with a freezing point of -12 0 C, refractive index of 1.4850 and specific gravity of 0.930 at 25 0 C.
  • the two most commonly used solid organic crystalline sunscreens are 2-hydroxy 4-methoxy benzophenone (called Benzophenone-3 ) , and Parsol 1789 (butyl-methoxy dibenzoyl methane) . These two sunscreens are difficult to dissolve and keep in solution for use in sunscreen formulations for optimal SPF (Sun Protection Factor). Higher solvency for a sunscreen active is desirable as it allows higher concentrations of the sunscreen active ingredient in a formulation. This advantageously raises the SPF ratings for the formulations. As seen from the foregoing table, Additive Mixture A exhibits superiority over commonly used and marketed cosmetic emollients/materials in terms of amounts dissolved.
  • Additive Mixture A for the solid crystalline organic sunscreens is an advantageous effect in formulating sunscreen products for the skincare markets.
  • this ester mixture is an excellent solvent for the above mentioned organic sunscreens.
  • Additive Mixture A provides an anti-washoff effect. This effect is very attractive in formulating long lasting sunscreen products allowing the sunscreen to remain on the skin for longer time.
  • Additive Mixture A The solubility characteristics of Additive Mixture A are tabulated below.
  • the ester mixture is soluble in most commonly used solvents, emollients and vehicles employed in cosmetic product formulations.
  • the soap bars containing Additive Mixture A were found to run better in the extruder, to have better body with consistency than the control bars containing Finsolv TN, to have a transparent or pearlescent effect, and to have better body texture.
  • the bars containing Additive Mixture A produced dense bubbles, and a slippery feel was observed when the bars were wet. After drying, no stickiness was found on the skin. A pleasant soft silky feel with shine and gloss was observed and the skin felt well moisturized.
  • Transparent Combo bars were prepared utilizing the following ingredients in the amounts in the table, given as percent by weight:
  • a hand and body lotion was formulated with the following ingredients in the amounts stated:
  • Disperse carbomer in water Heat to 7O 0 C, add sorbitol and EDTA. Add all Part II ingredients together and heat to 7O 0 C. Add Part II ingredients to Part I ingredients with good mixing. Add triethanolamine, continue mixing. Add Glydant, continue mixing while allowing to cool to room temperature. Discharge and collect.
  • Each product was evaluated. The amount of sample used was 0.5 cc administered by syringe. Each product was evaluated for the following attributes and rated on a scale of 1 to 5, 1 being the best and 5 the worst. Each product was timed from moment of application to the end feel and judged on its absorption time. The products were applied onto the forearm and the opposite hand rubbing into the skin using 4 fingers. The forearm was cleaned with warm water and wiped dry before evaluating another sample. This procedure and scale is used in the rest of the examples in this application relating to sunscreens, skin creams and the like.
  • a waterproof sunscreen lotion was prepared from the following ingredients, in the amounts stated.
  • Formulations A-D so prepared were tested for skin feel, emolliency, slip, stickiness, water rinse-off resistance and moisturizing effect. Results are as follows.
  • a high SPF sunscreen lotion (cold process) was prepared from the following ingredients, in the amounts stated:
  • the high SPF sunscreen lotion was prepared from the ingredients, in the amounts stated.
  • Formulations A-D so prepared were tested for skin feel, emolliency, slip, water rinse-off resistance and moisturizing effect. Results are as follows.
  • a high SPF sunscreen lotion (cold process) was prepared from the following ingredients, in the amounts stated:
  • the high SPF sunscreen lotion was prepared from the ingredients set forth above by the following procedure.
  • Formulations A-D so prepared were tested for skin feel, emolliency, slip, water rinse-off resistance and moisturizing effect. Results are as follows.
  • a sunblock cream was prepared from the following ingredients, in the amounts stated:
  • the sunblock cream was prepared from the ingredients set forth above by the following procedure.
  • Formulations A-D so prepared were tested for skin feel, emolliency, slip, moisturizing effect and water rinse-off resistance. Results are as follows.
  • An emollient cleansing lotion was prepared from the following ingredients, in the amounts stated:
  • Fizul MD 318 C (Disodium oleamido 1 1 1 1 MIPA-sulphosuccinate)
  • Carbopol ETD 2001 resin 0 .2 0 .2 0 .2 0.2
  • the emollient cleansing lotion was prepared from the ingredients set forth above by the following procedure:
  • Disperse carbomer in water Add balance of sub-mixture I ingredients and heat to 75 0 C Mix sub-mixture II ingredients together and heat to 75 0 C. Add sub-mixture II to sub-mixture I with mixing. Combine sub-mixture III ingredients then add to sub-mixture I/II and begin cooling. At 4O 0 C add ingredient IV continue cooling to 3O 0 C.
  • Formulations A-D prepared were tested for slip, skin feel and emolliency. Results are as follows.
  • a hand and body lotion was prepared from the following ingredients, in the amounts stated:
  • the hand and body lotion was prepared from the ingredients set forth above by the following procedure:
  • Disperse carbomer in water Heat to 7O 0 C.
  • Add sorbitol and tetrasodium EDTA Weigh all sub-mixture II ingredients together and heat to 75 0 C.
  • Formulations A-D so prepared were tested for skin feel, slip and emolliency.
  • a light body lotion was prepared from the following ingredients, in the amounts stated:
  • the light body lotion was prepared from the ingredients set forth above by the following procedure:
  • a non-whitening anti-perspirant stick was prepared from the following ingredients, in the amounts stated:
  • the non-whitening antiperspirant stick was prepared from the ingredients set forth above by the following procedure .
  • Formulation A-D so prepared were tested for emolliency, skin feel, slip, stick structure and tackiness. Results are as follows.
  • Deodorant sticks were prepared from the following ingredients, in the amounts stated:
  • the procedure was as follows. Charge all ingredients in to a suitable vessel. Heat to 8O 0 C, with mixing, allowing all ingredients to dissolve. Cool to 6O 0 C and cast into stick moulds .
  • Formulations A-D prepared were tested for skin feel, slip, stick structure, emolliency and tackiness. Results are as follows .
  • a pump spray deodorant was prepared from the following ingredients, in the amounts stated:
  • the pump spray deodorant was prepared from the ingredients set forth above by the following procedure:
  • Formulations A-D so prepared were tested for skin feel, slip, dryness, emolliency and tackiness.
  • a cream antiperspirant was prepared from the following ingredients in the amounts stated:
  • the cream antiperspirant was prepared from the ingredients set forth above by the following procedure:
  • a 2-in-l conditioning shampoo (opaque cream type) was prepared from the following ingredients, in the amounts stated:
  • the shampoo was prepared from the ingredients set forth above by the following procedure:
  • Table A compares the properties of the shampoos of formulations A-D.
  • Table B compares foam results for the shampoos of formulations A-D in a standard foaming test.
  • Table C compares the effects of the shampoos of formulations A, B, C and D.
  • Procedure rinse hair tresses under tap water for 15 seconds. Rinsed hair tresses were treated with shampoo. Shampooed for 5 minutes. Remove the tresses and rinse with running tap water for 15 seconds. Air dry. Perform wet and dry comb tests and assess detangling quality. Assess shine/gloss and dry feel/handle.
  • a clear conditioning shampoo was prepared from the following ingredients in the amounts stated:
  • the clear conditioning shampoo was prepared from the ingredients set forth above by the following procedure:
  • Table A Compares the properties of shampoo preparation of formulation A, B, C and D.
  • Foam results of clear conditioning shampoo preparation of formulation A, B, C and D (using the method described in Example 17) .
  • Table C Compares the effects of shampoo of formulations A, B, C and D on hair tresses (using the method as described in Example 17) .
  • a shower and bath gel was prepared from the following ingredients, in the amounts stated:
  • the shower and bath gel was prepared from the ingredients set forth above by the following procedure.
  • Table A compares the properties of shower and bath gel preparation of formulation of A, B, C and D.
  • a foaming facial cleanser cream was prepared from the following ingredients, in the amounts stated:
  • the foaming facial cleanser cream was prepared from the ingredients, in the amounts stated, by the following procedure :
  • Table A compares the properties of facial cleanser cream of formulation A, B, C and D.
  • Foam results of foaming facial cleanse creme (tested as described in Example 17 above) .

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  • Cosmetics (AREA)

Abstract

La présente invention a pour objet une composition cosmétique comprenant (a) un ester d'un acide aromatique facultativement substitué (par exemple l'acide benzoïque) et d'un alcool primaire en C12 et (b) un ester d'un acide aromatique facultativement substitué (par exemple l'acide benzoïque) et d'un alcool primaire en C14. Les esters (a) et (b) améliorent le caractère émollient des compositions cosmétiques comprenant des compositions d'écran solaire, d'antitranspirant et d'hygiène personnelle. Il est décrit une composition additive comprenant les esters (a) et (b) dans une proportion substantielle, qui peuvent être mélangés avec d'autres composants pour produire la composition cosmétique.
PCT/GB2008/051228 2007-12-28 2008-12-23 Compositions et leurs utilisations WO2009083736A1 (fr)

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GB0725264A GB0725264D0 (en) 2007-12-28 2007-12-28 Compositions and uses thereof

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AR (1) AR070055A1 (fr)
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017144865A1 (fr) * 2016-02-26 2017-08-31 RECKITT BENCKISER LAUNDRY DETERGENTS (No.1) BV Composition
DE202022107306U1 (de) 2021-12-30 2023-02-06 Ptt Global Chemical Public Company Limited Zusammensetzung von Alkylbenzoaten für Kosmetika

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US4293544A (en) * 1979-03-07 1981-10-06 Finetex Incorporated Fluid and semi-fluid compositions including benzoate esters
US4323694A (en) * 1981-04-13 1982-04-06 Finetex, Inc. Benzoic acid esters
WO1988006878A1 (fr) * 1987-03-12 1988-09-22 Nigra Thomas P Composition pharmaceutique contenant des esters d'acide benzoique et kit
US4917882A (en) * 1989-03-16 1990-04-17 Amway Corporation Gel-type sunscreen composition
US20060121166A1 (en) * 2004-12-06 2006-06-08 Milan Jeckle Ultraviolet light reflective composition for fishing apparatus
US20070207104A1 (en) * 2006-03-06 2007-09-06 Borish Edward T Antimicrobial esters
EP1905483A1 (fr) * 2006-09-27 2008-04-02 Cognis IP Management GmbH Mélanges d'esters alkyliques d'acide benzoïque

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293544A (en) * 1979-03-07 1981-10-06 Finetex Incorporated Fluid and semi-fluid compositions including benzoate esters
US4323694A (en) * 1981-04-13 1982-04-06 Finetex, Inc. Benzoic acid esters
WO1988006878A1 (fr) * 1987-03-12 1988-09-22 Nigra Thomas P Composition pharmaceutique contenant des esters d'acide benzoique et kit
US4917882A (en) * 1989-03-16 1990-04-17 Amway Corporation Gel-type sunscreen composition
US20060121166A1 (en) * 2004-12-06 2006-06-08 Milan Jeckle Ultraviolet light reflective composition for fishing apparatus
US20070207104A1 (en) * 2006-03-06 2007-09-06 Borish Edward T Antimicrobial esters
EP1905483A1 (fr) * 2006-09-27 2008-04-02 Cognis IP Management GmbH Mélanges d'esters alkyliques d'acide benzoïque

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* Cited by examiner, † Cited by third party
Title
"International Cosmetic Ingredient Dictionary and Handbook", 2006, COSMETIC, TOILETRY AND FRAGRANCE ASSOCIATION, WASHINGTON DC 20036-4702, XP002525733 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017144865A1 (fr) * 2016-02-26 2017-08-31 RECKITT BENCKISER LAUNDRY DETERGENTS (No.1) BV Composition
DE202022107306U1 (de) 2021-12-30 2023-02-06 Ptt Global Chemical Public Company Limited Zusammensetzung von Alkylbenzoaten für Kosmetika

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GB0725264D0 (en) 2008-02-06
TW200936172A (en) 2009-09-01
AR070055A1 (es) 2010-03-10

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