WO2009066537A1 - Immunoregulatory function inducer and food composition - Google Patents

Immunoregulatory function inducer and food composition Download PDF

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Publication number
WO2009066537A1
WO2009066537A1 PCT/JP2008/069210 JP2008069210W WO2009066537A1 WO 2009066537 A1 WO2009066537 A1 WO 2009066537A1 JP 2008069210 W JP2008069210 W JP 2008069210W WO 2009066537 A1 WO2009066537 A1 WO 2009066537A1
Authority
WO
WIPO (PCT)
Prior art keywords
lactic acid
acid bacterium
processed product
bacterium
food composition
Prior art date
Application number
PCT/JP2008/069210
Other languages
French (fr)
Japanese (ja)
Inventor
Seiya Makino
Shuji Ikegami
Noriko Tsuji
Original Assignee
Meiji Dairies Corporation
National Institute Of Advanced Industrial Science And Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Dairies Corporation, National Institute Of Advanced Industrial Science And Technology filed Critical Meiji Dairies Corporation
Priority to JP2009542511A priority Critical patent/JP5527690B2/en
Publication of WO2009066537A1 publication Critical patent/WO2009066537A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus

Abstract

The object is to provide a lactic acid bacterium belonging to the genus Lactococcus, which has a high anti-inflammatory effect on an inflammatory bowel disease. Thus, provided are: a lactic acid bacterium belonging to the genus Lactococcus as typified by Lactococcus lactis OLS3301 strain and/or a processed product of the lactic acid bacterium; an immunoregulatory function inducer comprising the lactic acid bacterium and/or the processed product of the lactic acid bacterium as an active ingredient; and a food composition containing an effective amount of the lactic acid bacterium and/or the processed product of the lactic acid bacterium. The bacterium and/or the processed product thereof is capable of causing an immunocyte to produce IL-10, which is an anti-inflammatory cytokine, in a large quantity, and therefore can prevent an inflammation caused by an excess inflammatory response. The bacterium and/or the processed product thereof can also prevent an inflammation in the skin.
PCT/JP2008/069210 2007-11-19 2008-10-23 Immunoregulatory function inducer and food composition WO2009066537A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009542511A JP5527690B2 (en) 2007-11-19 2008-10-23 Immunoregulatory function inducer and food composition

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007298754 2007-11-19
JP2007-298754 2007-11-19

Publications (1)

Publication Number Publication Date
WO2009066537A1 true WO2009066537A1 (en) 2009-05-28

Family

ID=40667364

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/069210 WO2009066537A1 (en) 2007-11-19 2008-10-23 Immunoregulatory function inducer and food composition

Country Status (2)

Country Link
JP (1) JP5527690B2 (en)
WO (1) WO2009066537A1 (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011148710A (en) * 2010-01-19 2011-08-04 Snow Brand Milk Prod Co Ltd Prophylactic and/or therapeutic agent for inflammatory bowel disease and/or irritable bowel syndrome
JP2014501100A (en) * 2010-12-17 2014-01-20 コンパニ・ジェルベ・ダノン Lactococcus lactis strain for use in improving the pathological state of the digestive tract
JP6298912B1 (en) * 2017-04-10 2018-03-20 有限会社バイオ研 Method for producing lactic acid bacteria and composition for immunomodulation
JP2018078832A (en) * 2016-11-16 2018-05-24 株式会社明治 Microorganism heat treatment method
KR102154254B1 (en) * 2020-04-29 2020-09-09 (주)녹십자웰빙 Novel Lactic Acid Bacteria with Excellent Immune function enhancing effect and Food Composition Containing the Same and Health Functional Food Composition Containing the Same and Probiotics comprising the Same
US10806769B2 (en) 2016-03-31 2020-10-20 Gojo Industries, Inc. Antimicrobial peptide stimulating cleansing composition
CN111818812A (en) * 2018-03-15 2020-10-23 麒麟控股株式会社 Composition for improving skin condition
US10874700B2 (en) 2016-03-31 2020-12-29 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
US11466582B2 (en) 2016-10-12 2022-10-11 General Electric Company Turbine engine inducer assembly
US11564879B2 (en) 2016-11-23 2023-01-31 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
CN116121110A (en) * 2022-10-28 2023-05-16 益加生物科技成都有限公司 Lactococcus lactis YJ0801 with strong antibacterial and anti-inflammatory effects and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005154387A (en) * 2003-11-28 2005-06-16 National Institute Of Agrobiological Sciences Lactobacilli inducing immunomodulative function or component thereof and method for obtaining the same
JP2007269737A (en) * 2006-03-31 2007-10-18 Morinaga Milk Ind Co Ltd Interleukin production regulator, pharmaceutical composition and food and drink comprising the interleukin production regulator and method for producing the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005154387A (en) * 2003-11-28 2005-06-16 National Institute Of Agrobiological Sciences Lactobacilli inducing immunomodulative function or component thereof and method for obtaining the same
JP2007269737A (en) * 2006-03-31 2007-10-18 Morinaga Milk Ind Co Ltd Interleukin production regulator, pharmaceutical composition and food and drink comprising the interleukin production regulator and method for producing the same

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HIROMI KIMOTO ET AL.: "Nyugyoyo Nyusankin Lactococcus no Men'eki Chosetsu Sayo ni tsuite", JOURNALOF JAPANESE SOCIETY OF NUTRITION, AND FOOD SCIENCE SOKAI KOEN YOSHISHU, vol. 58TH, 2004, pages 123 *
MAKINO S. ET AL.: "Immunomodulatory efects of Lactococcus lactis subsp. lactis OLS3301 on dextran sulfate sodium-induced colitis in mice.", DAI 37 KAI PROCEEDINGS OF THE JAPANESE SOCIETY FOR IMMUNOLOGY, vol. 37, October 2007 (2007-10-01), pages 161 *
NORIKO TSUJI ET AL.: "IL-10 Sansei o Unagashi Men'eki Chosetsu ni Hataraku Probiotics", NIPPON NOGEI KAGAKUKAI TAIKAI KOEN YOSHISHU, vol. 2004, 2004, pages 217 *

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011148710A (en) * 2010-01-19 2011-08-04 Snow Brand Milk Prod Co Ltd Prophylactic and/or therapeutic agent for inflammatory bowel disease and/or irritable bowel syndrome
JP2014501100A (en) * 2010-12-17 2014-01-20 コンパニ・ジェルベ・ダノン Lactococcus lactis strain for use in improving the pathological state of the digestive tract
US10806769B2 (en) 2016-03-31 2020-10-20 Gojo Industries, Inc. Antimicrobial peptide stimulating cleansing composition
US10874700B2 (en) 2016-03-31 2020-12-29 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
US11633451B2 (en) 2016-03-31 2023-04-25 Gojo Industries, Inc. Antimicrobial peptide stimulating cleansing composition
US11846209B2 (en) 2016-10-12 2023-12-19 General Electric Company Turbine engine inducer assembly
US11466582B2 (en) 2016-10-12 2022-10-11 General Electric Company Turbine engine inducer assembly
JP2018078832A (en) * 2016-11-16 2018-05-24 株式会社明治 Microorganism heat treatment method
WO2018092678A1 (en) * 2016-11-16 2018-05-24 株式会社明治 Heat treatment method for microorganism
US11564879B2 (en) 2016-11-23 2023-01-31 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
JP6298912B1 (en) * 2017-04-10 2018-03-20 有限会社バイオ研 Method for producing lactic acid bacteria and composition for immunomodulation
JP2018174772A (en) * 2017-04-10 2018-11-15 有限会社バイオ研 Methods for producing lactic acid bacteria, and compositions for immunity modulation
CN111818812A (en) * 2018-03-15 2020-10-23 麒麟控股株式会社 Composition for improving skin condition
US11497778B2 (en) 2018-03-15 2022-11-15 Kirin Holdings Kabushiki Kaisha Composition for improving skin conditions
EP3766363A4 (en) * 2018-03-15 2022-01-05 Kirin Holdings Kabushiki Kaisha Composition for improving skin conditions
CN111818812B (en) * 2018-03-15 2023-09-26 麒麟控股株式会社 Composition for improving skin condition
KR102154254B1 (en) * 2020-04-29 2020-09-09 (주)녹십자웰빙 Novel Lactic Acid Bacteria with Excellent Immune function enhancing effect and Food Composition Containing the Same and Health Functional Food Composition Containing the Same and Probiotics comprising the Same
CN116121110A (en) * 2022-10-28 2023-05-16 益加生物科技成都有限公司 Lactococcus lactis YJ0801 with strong antibacterial and anti-inflammatory effects and application thereof

Also Published As

Publication number Publication date
JPWO2009066537A1 (en) 2011-04-07
JP5527690B2 (en) 2014-06-18

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