WO2009061152A3 - Composition for prevention and treatment of pain containing curcumin or pharmaceutically acceptable salt thereof as an active ingredient - Google Patents

Composition for prevention and treatment of pain containing curcumin or pharmaceutically acceptable salt thereof as an active ingredient Download PDF

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Publication number
WO2009061152A3
WO2009061152A3 PCT/KR2008/006576 KR2008006576W WO2009061152A3 WO 2009061152 A3 WO2009061152 A3 WO 2009061152A3 KR 2008006576 W KR2008006576 W KR 2008006576W WO 2009061152 A3 WO2009061152 A3 WO 2009061152A3
Authority
WO
WIPO (PCT)
Prior art keywords
pain
prevention
treatment
composition
pharmaceutically acceptable
Prior art date
Application number
PCT/KR2008/006576
Other languages
French (fr)
Other versions
WO2009061152A2 (en
Inventor
Seog Bae Oh
Sung Jun Jung
Seong Ah Kim
Dong-Kuk Ahn
Hyun Jeong Kim
Heung Sik Na
Original Assignee
Snu R&Db Foundation
Univ Korea Ind & Acad Coop
Seog Bae Oh
Sung Jun Jung
Seong Ah Kim
Dong-Kuk Ahn
Hyun Jeong Kim
Heung Sik Na
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Snu R&Db Foundation, Univ Korea Ind & Acad Coop, Seog Bae Oh, Sung Jun Jung, Seong Ah Kim, Dong-Kuk Ahn, Hyun Jeong Kim, Heung Sik Na filed Critical Snu R&Db Foundation
Publication of WO2009061152A2 publication Critical patent/WO2009061152A2/en
Publication of WO2009061152A3 publication Critical patent/WO2009061152A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

The present invention relates to a composition for prevention and treatment of pain containing curcurnin or pharmaceutically acceptable salts thereof as an active ingredient. The composition for prevention and treatment of pain according to the present invention may significantly inhibit the activation of TRPVl which causes all pain including dentalgia and inflammation induced by various stimulants such as temperature, capsaicin, and acids, effectively inhibit pain caused thereby, and be produced from natural products. Thus, the composition is biologically stable and may be used in the products for treatment and alleviation of pain, including analgesics, functional toothpastes for prevention and improvement of pain, functional foods, and food additives.
PCT/KR2008/006576 2007-11-08 2008-11-07 Composition for prevention and treatment of pain containing curcumin or pharmaceutically acceptable salt thereof as an active ingredient WO2009061152A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2007-0113574 2007-11-08
KR1020070113574A KR20090047637A (en) 2007-11-08 2007-11-08 Composition for prevention and treatment of pain containing curcumin or pharmaceutically acceptable salt thereof as an active ingredient

Publications (2)

Publication Number Publication Date
WO2009061152A2 WO2009061152A2 (en) 2009-05-14
WO2009061152A3 true WO2009061152A3 (en) 2009-06-25

Family

ID=40626351

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2008/006576 WO2009061152A2 (en) 2007-11-08 2008-11-07 Composition for prevention and treatment of pain containing curcumin or pharmaceutically acceptable salt thereof as an active ingredient

Country Status (2)

Country Link
KR (1) KR20090047637A (en)
WO (1) WO2009061152A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8722964B2 (en) 2009-04-23 2014-05-13 Transposagen Biopharmaceuticals, Inc. Genetically engineered or transgenic rats exhibiting a cancer phenotype due to a disruption of germline tumor suppressor genes
EP2449112A1 (en) 2009-07-01 2012-05-09 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for severe combined immunodeficiency (scid)
CA2859283C (en) 2011-12-16 2021-03-09 Transposagen Biopharmaceuticals, Inc. Trpc4 modulators for use in the treatment or prevention of pain
DE102012219219A1 (en) * 2012-10-22 2014-05-28 Uwe-Bernd Rose Pharmaceutical formulation containing curcumin
US9538782B2 (en) * 2013-03-15 2017-01-10 Altria Client Services Llc Inhibition of sensory irritation during consumption of smokeless tobacco products using a combinatorial approach
US10286028B2 (en) * 2014-02-20 2019-05-14 Indena S.P.A. Compositions containing extracts of Curcuma longa and Echinacea angustifolia which are useful to reduce peripheral inflammation and pain

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6201014B1 (en) * 1997-06-10 2001-03-13 Reckitt & Colman Products Limited Therapeutically active compositions
JP2006347948A (en) * 2005-06-15 2006-12-28 Ryukyu Bio Resource Kaihatsu:Kk Pain relief/anti-inflammation troche for oral mucosa
KR20070086093A (en) * 2004-11-13 2007-08-27 메타프로테오믹스, 엘엘씨 Curcuminoid compositions exhibiting synergistic inhibition of the expression and/or activity of cyclooxygenase-2

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6201014B1 (en) * 1997-06-10 2001-03-13 Reckitt & Colman Products Limited Therapeutically active compositions
KR20070086093A (en) * 2004-11-13 2007-08-27 메타프로테오믹스, 엘엘씨 Curcuminoid compositions exhibiting synergistic inhibition of the expression and/or activity of cyclooxygenase-2
JP2006347948A (en) * 2005-06-15 2006-12-28 Ryukyu Bio Resource Kaihatsu:Kk Pain relief/anti-inflammation troche for oral mucosa

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LEVINE J.D. ET AL.: "TRP channels: targets for the relief of pain.", BIOCHIM BIOPHYS ACTA., vol. 1772, no. 8, August 2007 (2007-08-01), pages 989 - 1003 *
MARTELLI L ET AL.: "A potential role for the vanilloid receptor TRPV1 in the therapeutic effect of curcumin in dinitrobenzene sulphonic acid-induced colitis in mice.", NEUROGASTROENTEROL MOTIL., vol. 19, no. 8, August 2007 (2007-08-01), pages 668 - 674 *

Also Published As

Publication number Publication date
KR20090047637A (en) 2009-05-13
WO2009061152A2 (en) 2009-05-14

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