WO2009054258A1 - 骨再生組成物製造器具、骨再生組成物の製造方法、骨再生組成物、および骨再生方法 - Google Patents

骨再生組成物製造器具、骨再生組成物の製造方法、骨再生組成物、および骨再生方法 Download PDF

Info

Publication number
WO2009054258A1
WO2009054258A1 PCT/JP2008/068214 JP2008068214W WO2009054258A1 WO 2009054258 A1 WO2009054258 A1 WO 2009054258A1 JP 2008068214 W JP2008068214 W JP 2008068214W WO 2009054258 A1 WO2009054258 A1 WO 2009054258A1
Authority
WO
WIPO (PCT)
Prior art keywords
bone regeneration
composition
producing
related cells
regeneration composition
Prior art date
Application number
PCT/JP2008/068214
Other languages
English (en)
French (fr)
Inventor
Shinya Yoshida
Akira Kobayashi
Motokazu Watanabe
Junya Toguchida
Tomoki Aoyama
Original Assignee
Kaneka Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaneka Corporation filed Critical Kaneka Corporation
Publication of WO2009054258A1 publication Critical patent/WO2009054258A1/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3847—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3821—Bone-forming cells, e.g. osteoblasts, osteocytes, osteoprogenitor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Abstract

　骨再生に関わる骨再生関連細胞を、細胞分離器（１）を用いて捕捉する。回収用シリンジ（５）を用いて、細胞分離器（１）に、洗浄液を注入し、骨再生関連細胞を細胞分離器（１）から流出させる。細胞分離器（１）から流出した骨再生関連細胞を分離容器（６）に回収し、該混合容器（６）において、骨再生関連細胞と支持体とを混合する。これにより、骨再生に関わる骨再生関連細胞を含む試料からの該骨再生関連細胞の分離と、該骨再生関連細胞と支持体との混合とを、一連の操作として閉鎖系内で行う。これにより、本発明は、培養操作を行うことなく、閉鎖系内で簡便かつ迅速に骨再生組成物を製造することが可能な骨再生組成物製造器具、骨再生組成物の製造方法、骨再生組成物、および骨再生方法を提供する。
PCT/JP2008/068214 2007-10-24 2008-10-07 骨再生組成物製造器具、骨再生組成物の製造方法、骨再生組成物、および骨再生方法 WO2009054258A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-276872 2007-10-24
JP2007276872A JP5515133B2 (ja) 2007-10-24 2007-10-24 骨再生組成物製造器具

Publications (1)

Publication Number Publication Date
WO2009054258A1 true WO2009054258A1 (ja) 2009-04-30

Family

ID=40579364

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/068214 WO2009054258A1 (ja) 2007-10-24 2008-10-07 骨再生組成物製造器具、骨再生組成物の製造方法、骨再生組成物、および骨再生方法

Country Status (2)

Country Link
JP (1) JP5515133B2 (ja)
WO (1) WO2009054258A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017170925A1 (ja) * 2016-03-30 2017-10-05 ロート製薬株式会社 Ｅｇｆｒ及びｍｉｃ－ａｂからなる群より選択される少なくとも１種の細胞表面マーカーを高発現する間葉系幹細胞及びその調製方法、並びに上記間葉系幹細胞を含む医薬組成物及びその調製方法
CN107312707A (zh) * 2017-08-17 2017-11-03 卢建熙 间充质干细胞的采集装置及采集方法

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5562754B2 (ja) * 2010-07-30 2014-07-30 オリンパス株式会社 細胞処理システム
JP2012095815A (ja) * 2010-11-01 2012-05-24 Hi-Lex Corporation 骨補綴材
JP5738582B2 (ja) * 2010-12-06 2015-06-24 株式会社カネカ プライミング時の気泡の除去を簡便にする部材を備えた細胞溶液処理器具およびその使用方法
JP2012139142A (ja) * 2010-12-28 2012-07-26 Kaneka Corp 造血幹細胞分離材または分離方法
JP5849466B2 (ja) * 2011-06-30 2016-01-27 セイコーエプソン株式会社 分離装置
US9427512B2 (en) * 2012-06-08 2016-08-30 Pall Corporation Filter device
US9421317B2 (en) * 2012-06-08 2016-08-23 Pall Corporation Cell harvesting device and system
JPWO2018097198A1 (ja) * 2016-11-28 2019-10-17 株式会社バイオ未来工房 間葉系幹細胞の分離方法及びリン酸カルシウム類を含有する不織布の使用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997026326A1 (en) * 1996-01-16 1997-07-24 Depuy Orthopaedics, Inc. Isolation of precursor cells from hematopoietic and non-hematopoietic tissues and their use
JP2001161352A (ja) * 1999-12-03 2001-06-19 Asahi Medical Co Ltd 生体組織再生用細胞の分離方法、生体組織再生用細胞及び生体組織再生用細胞分離装置
WO2006014159A2 (en) * 2004-07-01 2006-02-09 Macropore Biosurgery Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
WO2007046501A1 (ja) * 2005-10-21 2007-04-26 Kaneka Corporation 幹細胞の分離材および分離方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997026326A1 (en) * 1996-01-16 1997-07-24 Depuy Orthopaedics, Inc. Isolation of precursor cells from hematopoietic and non-hematopoietic tissues and their use
JP2001161352A (ja) * 1999-12-03 2001-06-19 Asahi Medical Co Ltd 生体組織再生用細胞の分離方法、生体組織再生用細胞及び生体組織再生用細胞分離装置
WO2006014159A2 (en) * 2004-07-01 2006-02-09 Macropore Biosurgery Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
WO2007046501A1 (ja) * 2005-10-21 2007-04-26 Kaneka Corporation 幹細胞の分離材および分離方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017170925A1 (ja) * 2016-03-30 2017-10-05 ロート製薬株式会社 Ｅｇｆｒ及びｍｉｃ－ａｂからなる群より選択される少なくとも１種の細胞表面マーカーを高発現する間葉系幹細胞及びその調製方法、並びに上記間葉系幹細胞を含む医薬組成物及びその調製方法
JPWO2017170925A1 (ja) * 2016-03-30 2019-02-07 ロート製薬株式会社 Ｅｇｆｒ及びｍｉｃ−ａｂからなる群より選択される少なくとも１種の細胞表面マーカーを高発現する間葉系幹細胞及びその調製方法、並びに上記間葉系幹細胞を含む医薬組成物及びその調製方法
CN107312707A (zh) * 2017-08-17 2017-11-03 卢建熙 间充质干细胞的采集装置及采集方法
CN107312707B (zh) * 2017-08-17 2020-05-19 卢建熙 间充质干细胞的采集装置及采集方法

Also Published As

Publication number Publication date
JP2009101022A (ja) 2009-05-14
JP5515133B2 (ja) 2014-06-11

Similar Documents

Publication Publication Date Title
WO2009054258A1 (ja) 骨再生組成物製造器具、骨再生組成物の製造方法、骨再生組成物、および骨再生方法
TW200515927A (en) Method of preparing cell concentrate and cell composition
WO2010022286A3 (en) Apparatus for removal of specific seed tissue or structure for seed analysis
WO2008054825A8 (en) Mixed cell populations for tissue repair and separation technique for cell processing
WO2010094015A3 (en) System and related method for concentrating biological culture and circulating biological culture and process fluid
BR112015004003A2 (pt) aparelho de processamento de tecido e método para processar tecido adiposo
WO2008108412A1 (ja) 血清調製方法及び血清調製装置
WO2009031678A1 (ja) ヒト間葉系幹細胞濃縮方法
EP3174973B1 (en) Method and assembly for extraction of regenerative cellular components from adipose tissue
EP1881062A4 (en) METHOD FOR CULTURING MESENCHYMAL STEM CELL AND METHOD FOR PRODUCING SUPPORT MATERIAL FOR BIOLOGICAL TISSUE
CN102220278A (zh) 一种分离原代成人肝细胞的方法及其专用无菌器械盒
CN105802957B (zh) 一种从煤层水样中提取微生物总dna的方法
CN103725670A (zh) 从生物样本提取核酸的方法
CN111440759A (zh) 同时分离提取玉米细胞核和叶绿体的方法
EP2345434A3 (en) Method and device for synovial cell-charged collagen membrane or gel
CN204185484U (zh) 一种用于核酸的快速提取装置
WO2008149797A1 (ja) 誘電体微粒子濃縮装置
CN101978974A (zh) 一种蛋白核小球藻破壁提取生物活性物质的方法
WO2007032817A3 (en) Pure mirna sample preparation method
MY159740A (en) Starter kit for the production of pure and high quality microalgae
WO2006073692A3 (en) Isolation and purification of human insulin producing cells for the treatment of insulin dependent diabetes
EP2880147B1 (de) Vorrichtung und verfahren zur behandlung eines filtrationsmediums
CN104818238A (zh) 一种鸡肠上皮细胞分离培养方法
CN204607994U (zh) 一种核酸快速提取装置
CN102242054A (zh) 全封闭式细胞和细胞因子制备装置及其制备方法

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08843217

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08843217

Country of ref document: EP

Kind code of ref document: A1