WO2009015752A3 - Substanzen zum schutz von zellen und/oder geweben - Google Patents

Substanzen zum schutz von zellen und/oder geweben Download PDF

Info

Publication number
WO2009015752A3
WO2009015752A3 PCT/EP2008/005651 EP2008005651W WO2009015752A3 WO 2009015752 A3 WO2009015752 A3 WO 2009015752A3 EP 2008005651 W EP2008005651 W EP 2008005651W WO 2009015752 A3 WO2009015752 A3 WO 2009015752A3
Authority
WO
WIPO (PCT)
Prior art keywords
tissues
substances
cells
protection
relates
Prior art date
Application number
PCT/EP2008/005651
Other languages
English (en)
French (fr)
Other versions
WO2009015752A2 (de
Inventor
Ralf Loesel
Benito Yard
Grietje Beck
Original Assignee
Ralf Loesel
Benito Yard
Grietje Beck
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ralf Loesel, Benito Yard, Grietje Beck filed Critical Ralf Loesel
Priority to EP08784693A priority Critical patent/EP2187735A2/de
Priority to AU2008281106A priority patent/AU2008281106A1/en
Priority to US12/452,889 priority patent/US20100129436A1/en
Priority to JP2010518519A priority patent/JP2010534691A/ja
Priority to CA2694265A priority patent/CA2694265A1/en
Priority to CN200880101022A priority patent/CN101765367A/zh
Priority to BRPI0814337-4A2A priority patent/BRPI0814337A2/pt
Publication of WO2009015752A2 publication Critical patent/WO2009015752A2/de
Publication of WO2009015752A3 publication Critical patent/WO2009015752A3/de
Priority to ZA2010/00483A priority patent/ZA201000483B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Die Erfindung betrifft Substanzen, die zum Schutz von Zellen und/oder Gewebe geeignet sind.
PCT/EP2008/005651 2007-07-30 2008-07-10 Substanzen zum schutz von zellen und/oder geweben WO2009015752A2 (de)

Priority Applications (8)

Application Number Priority Date Filing Date Title
EP08784693A EP2187735A2 (de) 2007-07-30 2008-07-10 Substanzen zum schutz von zellen und/oder geweben
AU2008281106A AU2008281106A1 (en) 2007-07-30 2008-07-10 Substances for the protection of cells and/or tissues
US12/452,889 US20100129436A1 (en) 2007-07-30 2008-07-10 Subtances for the protection of cells and/or tissues
JP2010518519A JP2010534691A (ja) 2007-07-30 2008-07-10 細胞および／または組織の保護のための物質
CA2694265A CA2694265A1 (en) 2007-07-30 2008-07-10 Substances for the protection of cells and/or tissues
CN200880101022A CN101765367A (zh) 2007-07-30 2008-07-10 保护细胞和/或组织的物质
BRPI0814337-4A2A BRPI0814337A2 (pt) 2007-07-30 2008-07-10 Substância para a proteção de células ou tecidos, preparado, e uso de uma substância
ZA2010/00483A ZA201000483B (en) 2007-07-30 2010-01-21 Substances for the protection of cells and/or tissues

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007035642A DE102007035642A1 (de) 2007-07-30 2007-07-30 Substanzen zur Protektion von Zellen und Geweben gegen Schädigung durch ungünstige Bedingungen
DE102007035642.2 2007-07-30

Publications (2)

Publication Number Publication Date
WO2009015752A2 WO2009015752A2 (de) 2009-02-05
WO2009015752A3 true WO2009015752A3 (de) 2009-04-16

Family

ID=39816962

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/005651 WO2009015752A2 (de) 2007-07-30 2008-07-10 Substanzen zum schutz von zellen und/oder geweben

Country Status (11)

Country Link
US (1) US20100129436A1 (de)
EP (1) EP2187735A2 (de)
JP (1) JP2010534691A (de)
KR (1) KR20100094446A (de)
CN (1) CN101765367A (de)
AU (1) AU2008281106A1 (de)
BR (1) BRPI0814337A2 (de)
CA (1) CA2694265A1 (de)
DE (1) DE102007035642A1 (de)
WO (1) WO2009015752A2 (de)
ZA (1) ZA201000483B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL2004569C2 (en) * 2010-04-16 2011-10-18 Angteq B V Compounds for prevention of cell injury.
EP2422769A1 (de) 2010-08-17 2012-02-29 Novaliq GmbH Zusammensetzungen und Verfahren für verbesserte Organtransplantaterhaltung und -annahme
JP6117789B2 (ja) * 2011-09-06 2017-04-19 ノバリック ゲーエムベーハー 親油性ドーパミン誘導体およびその使用

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2298291A (en) * 1935-06-15 1942-10-13 Sharp & Dohme Inc Alkyl catechol
US2848335A (en) * 1954-03-25 1958-08-19 Eastman Kodak Co Stabilization of normally oxidizable materials with hydroxybenzamide compounds
DE2153825A1 (de) * 1970-10-30 1972-05-04 F Hoffmann La Roche & Co AG, Basel (Schweiz) Phenathylamide
DE2254566A1 (de) * 1971-11-15 1973-05-24 Scherico Ltd Substituierte aryl- und aralkylamide
DE2755198A1 (de) * 1976-12-15 1978-06-22 Procter & Gamble Dihydroxybenzoesaeure-derivate sowie dieselben enthaltende schmerzen und entzuendungen lindernde mittel
EP0142241A1 (de) * 1983-09-13 1985-05-22 Kureha Kagaku Kogyo Kabushiki Kaisha Dihydroxybenzamid-Derivate mit entzündungshemmender Wirkung
EP1057405A1 (de) * 1999-06-02 2000-12-06 MG Pharmacy Ltd. Aufbewahrungsmittel zur Konservierung von tierischen Zellen, Geweben und Organen und entsprechendes Verfahren
WO2004110145A1 (de) * 2003-06-13 2004-12-23 Biotest Ag Verfahren und apparatur zur konservierung des endothels in isolierten hohlorganen und biologischen gefässen

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1912956A1 (de) * 1969-03-14 1970-09-24 Hoechst Ag Verfahren zur Herstellung von p-Toluolsulfochlorid
US3860630A (en) * 1970-10-30 1975-01-14 Hoffmann La Roche Phenethylamide derivatives
GB2168976A (en) * 1984-12-20 1986-07-02 Procter & Gamble Amides and compositions thereof having anti-inflammatory activity
DE29504589U1 (de) * 1995-03-13 1996-04-18 Levi, Ina, Dr., 14165 Berlin Mittel zur Behandlung von Infektionskrankheiten und zur Verlängerung der Lebensfähigkeit von Transplantationsgewebe
CN100413961C (zh) * 1996-09-05 2008-08-27 研究发展基金会 用咖啡酸苯乙酯衍生物、辣椒素和树脂毒素抑制NF-κB
NZ514515A (en) * 1999-03-23 2003-11-28 Global Cardiac Solutions Pty L Organ arrest, protection and preservation using a potassium channel operator and/or adenosine receptor and a local anaesthetic
JP2001215711A (ja) * 2000-02-01 2001-08-10 Fuji Photo Film Co Ltd タンニング現像薬、ハロゲン化銀感光材料、タンニング現像液およびレリーフ画像形成方法
US6548484B1 (en) * 2000-04-12 2003-04-15 International Medical Innovations, Inc. Pharmaceutical dopamine glycoconjugate compositions and methods of their preparation
JP4908718B2 (ja) * 2000-07-05 2012-04-04 株式会社大塚製薬工場 細胞・組織保存液
JPWO2004019680A1 (ja) * 2002-08-30 2006-01-05 株式会社ビーエムジー 臓器、組識または細胞の保護および保存のための組成物およびその利用
AU2003286474A1 (en) * 2002-10-18 2004-05-04 The General Hospital Corporation Compositions, solutions, and methods used for transplantation
DE10335726A1 (de) * 2003-08-05 2005-03-03 Bayer Cropscience Gmbh Verwendung von Hydroxyaromaten als Safener
JP2006188436A (ja) * 2004-12-28 2006-07-20 Japan Science & Technology Agency 医用ポリフェノール溶液
JP4931035B2 (ja) * 2005-05-02 2012-05-16 丞烋 玄 細胞・組織の凍結障害防止液及び凍結保存法

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2298291A (en) * 1935-06-15 1942-10-13 Sharp & Dohme Inc Alkyl catechol
US2848335A (en) * 1954-03-25 1958-08-19 Eastman Kodak Co Stabilization of normally oxidizable materials with hydroxybenzamide compounds
DE2153825A1 (de) * 1970-10-30 1972-05-04 F Hoffmann La Roche & Co AG, Basel (Schweiz) Phenathylamide
DE2254566A1 (de) * 1971-11-15 1973-05-24 Scherico Ltd Substituierte aryl- und aralkylamide
DE2755198A1 (de) * 1976-12-15 1978-06-22 Procter & Gamble Dihydroxybenzoesaeure-derivate sowie dieselben enthaltende schmerzen und entzuendungen lindernde mittel
EP0142241A1 (de) * 1983-09-13 1985-05-22 Kureha Kagaku Kogyo Kabushiki Kaisha Dihydroxybenzamid-Derivate mit entzündungshemmender Wirkung
EP1057405A1 (de) * 1999-06-02 2000-12-06 MG Pharmacy Ltd. Aufbewahrungsmittel zur Konservierung von tierischen Zellen, Geweben und Organen und entsprechendes Verfahren
WO2004110145A1 (de) * 2003-06-13 2004-12-23 Biotest Ag Verfahren und apparatur zur konservierung des endothels in isolierten hohlorganen und biologischen gefässen

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
ADER, P.: "Bioavailability and Metabolism of the Favonol Quercetin in the Pig", FREE READICAL BIOLOGY AND MEDICINE, vol. 28, no. 7, 2000, pages 1056 - 1067, XP002510367 *
CANNON, J.G.: "N-Isopropyl Derivatives of Dopamine and 5,6-Dihydroxy-2-aminotetralin", JOURNAL OF MEDICINAL CHEMISTRY, vol. 18, no. 12, 1975, pages 1212 - 1216, XP002510361 *
GINOS, J. Z.: "NEW DOPAMINERGIC AND POTENTIAL ANTI-PARKINSON COMPOUNDS. N,N-DISUBSTITUTED BETA-(3,4-DIHYDROXYPHENYL)ETHYLAMINES", JOURNAL OF MEDICINAL CHMIESTRY, vol. 21, no. 2, 1978, pages 160 - 165, XP002510360 *
HOWARTH, R. D.: "Some Derivatives of Catechol and Pyrogallol. Part I", JOURNAL OF THE CHEMICAL SOCIETY, 1946, pages 999 - 1003, XP009110719 *
KURTZ, A. P.: "Synthesis of compounds structurally related to poison ivy urushiol. 3. 3-n-Pentadecylcatechol and 3-n-alkylcatechols of varying side-chain length", JOURNAL OF MEDICINAL CHEMISTRY, vol. 14, no. 8, 1971, pages 729 - 732, XP002510366 *
MONTANARI, S: "Z1046, A Novel Peripheral Dopaminergic Agent", BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 6, no. 22, 1996, pages 2795 - 2800, XP002510358 *
NAITO, Y.: "Quantitative Structure-Activity Relationship of Catechol Derivatives Inhibiting 5-Lipoxygenase", CHEMICAL AND PHARMACEUTICAL BULLETIN, vol. 39, no. 7, 1991, pages 1736 - 1745, XP002510365 *
POLLAKIS, G.: "Competition between Inhibitors of the Trypanosome Alternative Oxidase (TAO) and Reduced Coenzyme Q9", BIOCHEMICAL PHARMACOLOGY, vol. 50, no. 8, 1995, pages 1207 - 1210, XP002510364 *
See also references of EP2187735A2 *
SHASHOUA. V. E.: "N-Docosahexaenoyl. 3, Hydroxytyramine: A Dopaminergic Compound that Penetrates the Blood-Brain Barrier and Suppresses Appetite", LIFE SCIENCES, vol. 58, no. 16, 1996, pages 1347 - 1357, XP002510363 *
TEMPLE, D.L.: "Adrenergic Sulfonanilides. 4. Centrally Active Beta-Andrenergic Agonists", JOURNAL OF MEDICINAL CHEMISTRY, vol. 19, no. 5, 1976, pages 626 - 633, XP002510359 *
TSENG, C.-F: "Inhibition of in Vitro Prostaglandin and Leukotriene Biosyntheses by Cinnamoyl-Beta-phenethylamine and N-Acyldopamine Derivatives", CHEMICAL AND PHARMACEUTICAL BULLETIN, vol. 40, no. 2, 1992, pages 396 - 400, XP002510362 *

Also Published As

Publication number Publication date
EP2187735A2 (de) 2010-05-26
US20100129436A1 (en) 2010-05-27
KR20100094446A (ko) 2010-08-26
ZA201000483B (en) 2011-03-30
BRPI0814337A2 (pt) 2014-10-14
CA2694265A1 (en) 2009-02-05
AU2008281106A1 (en) 2009-02-05
JP2010534691A (ja) 2010-11-11
DE102007035642A1 (de) 2009-02-12
CN101765367A (zh) 2010-06-30
WO2009015752A2 (de) 2009-02-05

Similar Documents

Publication Publication Date Title
IL184312A0 (en) Herbal compositions for the treatment of diabetes and/or conditions associated therewith
HK1207594A1 (en) Compositions and methods for the prevention and treatment of autoimmune conditions
WO2008124660A3 (en) Methods and compositions for the treatment of cancer
GB2462789B (en) Procedures and compositions for reservoir protection
HK1145214A1 (en) Risk scoring system for the prevention of malware
EP2127646A4 (de) Mittel zur linderung oder prävention von xerostomie
MX286273B (es) Composiciones y metodos para inhibicion de la via jak.
WO2008144395A3 (en) Tissue aperture securing and sealing apparatuses
IL229180A0 (en) Preparations and methods for the prevention of protein oxidation
WO2008144522A8 (en) Tissue securing and sealing apparatus and related methods of use
WO2008115262A3 (en) Hsp90 inhibitors containing a zinc binding moiety
WO2007081751A9 (en) Compositions and methods for the treatment of cancer
EP2152663A4 (de) Triarylverbindungen und zusammensetzungen damit
WO2007130725A3 (en) Use of hmgb1 for protection against ischemia reperfusion injury
IL211930A0 (en) Peptides and compositions for the prevention of cell adhesion
ZA201001261B (en) 1-amino-alklcyclohexane derivatives for the treatmrnt and prevention of hearing loss
WO2009114470A3 (en) Tetrahydroindole and tetrahdyroindazole as hsp90 inhibitors containing a zinc binding moiety
SI2170359T1 (sl) Uporaba kvasnih kosmičev pri zdravljenju in/ali preprečevanju hiperinzulinemije
WO2008054484A3 (en) Compositions, materials incorporating the compositions, and methods of using the compositions and materials
WO2009015752A3 (de) Substanzen zum schutz von zellen und/oder geweben
WO2009091274A9 (en) Appliance and procedure designed for the improvement of plant-production in the specially protected environment
EP2307558A4 (de) Zusammensetzungen und verfahren zum schutz nukleophiler gruppen
IL200795A0 (en) Prodrug compounds of (+)3-hydroxymorphinan, compositions comprising the same and use thereof
WO2008136852A3 (en) Methods and compositions related to the structure and function of apobec3g
WO2009039199A3 (en) Compositions comprising stat5 sirna and methods of use thereof

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200880101022.X

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08784693

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2010518519

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2694265

Country of ref document: CA

Ref document number: 502/DELNP/2010

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 12452889

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 2008281106

Country of ref document: AU

ENP Entry into the national phase

Ref document number: 20107004330

Country of ref document: KR

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2008784693

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2008281106

Country of ref document: AU

Date of ref document: 20080710

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: PI0814337

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20100128