WO2008133075A1 - 活性化免疫細胞の検出方法 - Google Patents

活性化免疫細胞の検出方法 Download PDF

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Publication number
WO2008133075A1
WO2008133075A1 PCT/JP2008/057254 JP2008057254W WO2008133075A1 WO 2008133075 A1 WO2008133075 A1 WO 2008133075A1 JP 2008057254 W JP2008057254 W JP 2008057254W WO 2008133075 A1 WO2008133075 A1 WO 2008133075A1
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WO
WIPO (PCT)
Prior art keywords
immunocyte
activated
detection
detecting
activation
Prior art date
Application number
PCT/JP2008/057254
Other languages
English (en)
French (fr)
Inventor
Kenji Yamamoto
Akiyoshi Hoshino
Kazuo Suzuki
Original Assignee
Sekisui Chemical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Sekisui Chemical Co., Ltd. filed Critical Sekisui Chemical Co., Ltd.
Priority to JP2008520458A priority Critical patent/JPWO2008133075A1/ja
Publication of WO2008133075A1 publication Critical patent/WO2008133075A1/ja

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56972White blood cells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/588Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

本発明の目的は、活性化により免疫細胞の表面に表出したタンパク質を高感度に検出することができる活性化免疫細胞の検出方法を提供することである。 本発明は、量子ドットを蛍光プローブとする抗体を用いて、活性化により免疫細胞の表面に表出したタンパク質を検出する活性化免疫細胞の検出方法である。
PCT/JP2008/057254 2007-04-12 2008-04-14 活性化免疫細胞の検出方法 WO2008133075A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008520458A JPWO2008133075A1 (ja) 2007-04-12 2008-04-14 活性化免疫細胞の検出方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-105264 2007-04-12
JP2007105264 2007-04-12

Publications (1)

Publication Number Publication Date
WO2008133075A1 true WO2008133075A1 (ja) 2008-11-06

Family

ID=39925533

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/057254 WO2008133075A1 (ja) 2007-04-12 2008-04-14 活性化免疫細胞の検出方法

Country Status (2)

Country Link
JP (1) JPWO2008133075A1 (ja)
WO (1) WO2008133075A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010271181A (ja) * 2009-05-21 2010-12-02 Kenji Yamamoto Ccr5を標的とする阻害剤の疾病治療効果、予防効果及び副作用を評価する方法
JP2016510115A (ja) * 2013-03-05 2016-04-04 ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャリゼーション ポリマードットを用いた解析のための方法およびシステム
JP2019525142A (ja) * 2016-06-21 2019-09-05 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 検体検出システム及び方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HOSHINO A. ET AL.: "Ryoshi DOt (QD) Hyoshiki Ko-mouse MPO Kotai o Mochiita Kekkan'en Hassho ni Kakawaru Kasseika Kochukyu MPO Bunshi no Keiko ni yoru Kenshutsu", 16TH JAPANESE SOCIETY FOR HOST DEFENSE RESEARCH GAKUJUTSU SOKAI KOEN SHOROKUSHU, 2005, pages 86 *
HOSHINO A. ET AL.: "Ryoshi Dot Keiko o Mochiita Kochukyu Karyunai Saiboshitsunai Sakkin Koso (myeloperoxidase; MPO) no Kenshutsu", CLINICAL TESTING, vol. 50, no. 12, 2006, pages 1409 - 1415 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010271181A (ja) * 2009-05-21 2010-12-02 Kenji Yamamoto Ccr5を標的とする阻害剤の疾病治療効果、予防効果及び副作用を評価する方法
JP2016510115A (ja) * 2013-03-05 2016-04-04 ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャリゼーション ポリマードットを用いた解析のための方法およびシステム
US10955419B2 (en) 2013-03-05 2021-03-23 University Of Washington Methods and systems for analysis using polymer dots
JP2019525142A (ja) * 2016-06-21 2019-09-05 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 検体検出システム及び方法
JP7097306B2 (ja) 2016-06-21 2022-07-07 シーメンス ヘルシニアーズ ネイザランド ビー.ブイ. 検体検出システム及び方法
US11519923B2 (en) 2016-06-21 2022-12-06 Siemens Healthineers Nederland B.V. Analyte detection system and method

Also Published As

Publication number Publication date
JPWO2008133075A1 (ja) 2010-07-22

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