WO2008120602A1 - 多孔質体の製造方法およびその用途 - Google Patents

多孔質体の製造方法およびその用途 Download PDF

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Publication number
WO2008120602A1
WO2008120602A1 PCT/JP2008/055465 JP2008055465W WO2008120602A1 WO 2008120602 A1 WO2008120602 A1 WO 2008120602A1 JP 2008055465 W JP2008055465 W JP 2008055465W WO 2008120602 A1 WO2008120602 A1 WO 2008120602A1
Authority
WO
WIPO (PCT)
Prior art keywords
porous body
assembly
frozen bodies
physical properties
raw material
Prior art date
Application number
PCT/JP2008/055465
Other languages
English (en)
French (fr)
Inventor
Toshinobu Sajiki
Satoshi Hirai
Original Assignee
Jms Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jms Co., Ltd. filed Critical Jms Co., Ltd.
Priority to US12/518,386 priority Critical patent/US8293046B2/en
Priority to CN2008800005953A priority patent/CN101541868B/zh
Priority to EP20080722731 priority patent/EP2100915A1/en
Publication of WO2008120602A1 publication Critical patent/WO2008120602A1/ja

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/28—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/0061—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof characterized by the use of several polymeric components
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2201/00—Foams characterised by the foaming process
    • C08J2201/04—Foams characterised by the foaming process characterised by the elimination of a liquid or solid component, e.g. precipitation, leaching out, evaporation
    • C08J2201/052—Inducing phase separation by thermal treatment, e.g. cooling a solution
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
    • C08J2367/04—Polyesters derived from hydroxy carboxylic acids, e.g. lactones
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2467/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicinal Preparation (AREA)

Abstract

　予め多孔質化された２以上の部材を接着剤等により接着させる方法ではなく、多孔質化処理によって、所望の領域において物性が異なる多孔質体を製造する方法を提供する。重合体と原料調製用溶媒とを含む原料を調製する。前記原料は、異なる組成の原料を少なくとも２種類以上調製する。そして、前記各原料を所望の形状となるように凍結して、前記各原料の凍結体を形成する。形成した凍結体同士を接触させ、前記凍結体の集合体を形成し、前記集合体を、前記凍結体の溶融が開始される条件下に曝した後、前記集合体を凍結乾燥する。これによって、物性が異なる領域を有する多孔質体を得ることができる。このような多孔質体は、例えば、癒着防止材や細胞培養等の足場材料として使用できる。
PCT/JP2008/055465 2007-03-30 2008-03-24 多孔質体の製造方法およびその用途 WO2008120602A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/518,386 US8293046B2 (en) 2007-03-30 2008-03-24 Process for production of porous body and uses thereof
CN2008800005953A CN101541868B (zh) 2007-03-30 2008-03-24 多孔质体的制备方法及其用途
EP20080722731 EP2100915A1 (en) 2007-03-30 2008-03-24 Process for production of porous body and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007092025 2007-03-30
JP2007-092025 2007-03-30

Publications (1)

Publication Number Publication Date
WO2008120602A1 true WO2008120602A1 (ja) 2008-10-09

Family

ID=39808184

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/055465 WO2008120602A1 (ja) 2007-03-30 2008-03-24 多孔質体の製造方法およびその用途

Country Status (6)

Country Link
US (1) US8293046B2 (ja)
EP (1) EP2100915A1 (ja)
JP (1) JP2008272453A (ja)
KR (1) KR101071334B1 (ja)
CN (1) CN101541868B (ja)
WO (1) WO2008120602A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009095522A (ja) * 2007-10-18 2009-05-07 National Institute For Materials Science 多孔質足場材
WO2011071074A1 (ja) * 2009-12-08 2011-06-16 株式会社ジェイ・エム・エス 多孔性部材、多孔化方法および前記多孔性部材の製造方法
JP2018524428A (ja) * 2015-06-02 2018-08-30 エシコン・インコーポレイテッドＥｔｈｉｃｏｎ， Ｉｎｃ． 長期吸収特性を呈する半結晶性のラクチドとε−カプロラクトンとのセグメント化コポリマーから製造された新規な発泡体及びフィルムに基づく吸収性医療用装置

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102488569B (zh) * 2011-11-15 2014-07-23 西安交通大学 一种立体微流道多孔支架的分层制造方法
US20200030072A1 (en) * 2016-10-05 2020-01-30 Children's Hospital Medical Center Shape memory patch for tissue repair

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02268766A (ja) * 1989-04-12 1990-11-02 Sumitomo Cement Co Ltd キトサン多孔質積層材料およびその製造方法
JPH06157807A (ja) * 1992-11-19 1994-06-07 Mitsui Toatsu Chem Inc 高分子多孔質体の製造方法
JP2001026664A (ja) * 1999-05-13 2001-01-30 Matsushita Electric Ind Co Ltd 多孔体の製造方法
JP2001212225A (ja) * 2000-02-04 2001-08-07 Toyobo Co Ltd 創傷被覆材

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US4238480A (en) * 1978-05-19 1980-12-09 Sawyer Philip Nicholas Method for preparing an improved hemostatic agent and method of employing the same
US4606910A (en) * 1984-06-28 1986-08-19 Interface Biomedical Laboratories Composite hemostatic article including a hemostatic agent onlay and methods for preparing the same
JPH0749490B2 (ja) 1989-04-06 1995-05-31 新田ゼラチン株式会社 コラーゲンスポンジの製造方法
US5188825A (en) * 1989-12-28 1993-02-23 Iles Martin C Freeze-dried dosage forms and methods for preparing the same
CA2060635A1 (en) * 1991-02-12 1992-08-13 Keith D'alessio Bioabsorbable medical implants
DE69307299T2 (de) 1992-02-14 1997-04-30 Univ Texas Mehrphasiges, biologisch abbaubares implantat/träger und verfahren zu seiner herstellung
US5514378A (en) 1993-02-01 1996-05-07 Massachusetts Institute Of Technology Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures
JP2987064B2 (ja) * 1994-09-12 1999-12-06 グンゼ株式会社 人工硬膜
JPH10234844A (ja) 1997-02-25 1998-09-08 Gunze Ltd 軟骨組織再生用基材及びこれを用いた軟骨組織再生法
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US6147135A (en) * 1998-12-31 2000-11-14 Ethicon, Inc. Fabrication of biocompatible polymeric composites
JP2002541925A (ja) 1999-04-16 2002-12-10 ラトガーズ，ザ ステイト ユニバーシティ 組織工学用多孔質ポリマー足場
US6333029B1 (en) 1999-06-30 2001-12-25 Ethicon, Inc. Porous tissue scaffoldings for the repair of regeneration of tissue
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FI19991852A (fi) 1999-09-01 2001-03-01 Yli Urpo Antti Uusi monikerroksinen materiaali, joka käsittää vaikuttavan ainesosan, ja sen valmistus
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US7166133B2 (en) * 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
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JP4529410B2 (ja) * 2003-10-23 2010-08-25 株式会社ジェイ・エム・エス 培養担体、該培養担体を使用した培養物と培養物の作製方法
JP4887838B2 (ja) * 2005-03-18 2012-02-29 株式会社ジェイ・エム・エス 多孔質体の製造方法およびそれを用いた多孔質体
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Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02268766A (ja) * 1989-04-12 1990-11-02 Sumitomo Cement Co Ltd キトサン多孔質積層材料およびその製造方法
JPH06157807A (ja) * 1992-11-19 1994-06-07 Mitsui Toatsu Chem Inc 高分子多孔質体の製造方法
JP2001026664A (ja) * 1999-05-13 2001-01-30 Matsushita Electric Ind Co Ltd 多孔体の製造方法
JP2001212225A (ja) * 2000-02-04 2001-08-07 Toyobo Co Ltd 創傷被覆材

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009095522A (ja) * 2007-10-18 2009-05-07 National Institute For Materials Science 多孔質足場材
WO2011071074A1 (ja) * 2009-12-08 2011-06-16 株式会社ジェイ・エム・エス 多孔性部材、多孔化方法および前記多孔性部材の製造方法
JP2018524428A (ja) * 2015-06-02 2018-08-30 エシコン・インコーポレイテッドＥｔｈｉｃｏｎ， Ｉｎｃ． 長期吸収特性を呈する半結晶性のラクチドとε−カプロラクトンとのセグメント化コポリマーから製造された新規な発泡体及びフィルムに基づく吸収性医療用装置

Also Published As

Publication number Publication date
KR101071334B1 (ko) 2011-10-07
US8293046B2 (en) 2012-10-23
JP2008272453A (ja) 2008-11-13
EP2100915A1 (en) 2009-09-16
CN101541868A (zh) 2009-09-23
KR20080111476A (ko) 2008-12-23
US20090319016A1 (en) 2009-12-24
CN101541868B (zh) 2011-11-16

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