WO2008117646A1 - Procédé de stabilisation d'un anticorps - Google Patents

Procédé de stabilisation d'un anticorps Download PDF

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Publication number
WO2008117646A1
WO2008117646A1 PCT/JP2008/054062 JP2008054062W WO2008117646A1 WO 2008117646 A1 WO2008117646 A1 WO 2008117646A1 JP 2008054062 W JP2008054062 W JP 2008054062W WO 2008117646 A1 WO2008117646 A1 WO 2008117646A1
Authority
WO
WIPO (PCT)
Prior art keywords
antibody
stabilization
serisin
hydrolysate
stabilizing
Prior art date
Application number
PCT/JP2008/054062
Other languages
English (en)
Japanese (ja)
Inventor
Yoshiaki Nishiya
Akiko Ogawa
Masahiro Sasaki
Hideyuki Yamada
Original Assignee
Toyo Boseki Kabushiki Kaisha
Seiren Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Boseki Kabushiki Kaisha, Seiren Co., Ltd. filed Critical Toyo Boseki Kabushiki Kaisha
Publication of WO2008117646A1 publication Critical patent/WO2008117646A1/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Food Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention porte sur un procédé de stabilisation d'un anticorps, qui est caractérisé par le fait que l'on amène l'anticorps à exister conjointement avec de la séricine et/ou un hydrolysat ou équivalent de celle-ci.
PCT/JP2008/054062 2007-03-26 2008-03-06 Procédé de stabilisation d'un anticorps WO2008117646A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-078935 2007-03-26
JP2007078935A JP4965302B2 (ja) 2007-03-26 2007-03-26 抗体の安定化方法

Publications (1)

Publication Number Publication Date
WO2008117646A1 true WO2008117646A1 (fr) 2008-10-02

Family

ID=39788382

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/054062 WO2008117646A1 (fr) 2007-03-26 2008-03-06 Procédé de stabilisation d'un anticorps

Country Status (2)

Country Link
JP (1) JP4965302B2 (fr)
WO (1) WO2008117646A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8952215B2 (en) 2005-10-18 2015-02-10 Nitto Boseki Co., Ltd. Antibody-producing transgenic silkworms and methods for producing the same

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6449221B2 (ja) * 2016-03-24 2019-01-09 三洋化成工業株式会社 粒子組成物、免疫測定用試薬及び免疫測定方法
CN109843182A (zh) * 2016-08-18 2019-06-04 普罗根尼蒂公司 使用可摄入装置获取样品的系统
JP6646691B2 (ja) * 2017-01-25 2020-02-14 三洋化成工業株式会社 抗原又は抗体固定化粒子及び免疫測定試薬の製造方法並びに免疫測定方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05279382A (ja) * 1992-01-17 1993-10-26 Boehringer Mannheim Gmbh タンパク質の安定化方法
JPH06186230A (ja) * 1992-12-17 1994-07-08 Doujin Iyaku Kako Kk 安定な抗体溶液及び抗体の安定化方法
WO2002086133A1 (fr) * 2001-04-17 2002-10-31 Seiren Kabushiki Kaisha Additifs de milieu et milieux de culture de cellules animales
JP2006047255A (ja) * 2003-08-20 2006-02-16 Seikagaku Kogyo Co Ltd 安定化剤及びブロッキング剤
JP2007151546A (ja) * 2005-11-11 2007-06-21 Toyobo Co Ltd 生体分子の安定化方法および組成物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006001912A (ja) * 2004-06-21 2006-01-05 Chugai Pharmaceut Co Ltd タンパク質製剤の安定化方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05279382A (ja) * 1992-01-17 1993-10-26 Boehringer Mannheim Gmbh タンパク質の安定化方法
JPH06186230A (ja) * 1992-12-17 1994-07-08 Doujin Iyaku Kako Kk 安定な抗体溶液及び抗体の安定化方法
WO2002086133A1 (fr) * 2001-04-17 2002-10-31 Seiren Kabushiki Kaisha Additifs de milieu et milieux de culture de cellules animales
JP2006047255A (ja) * 2003-08-20 2006-02-16 Seikagaku Kogyo Co Ltd 安定化剤及びブロッキング剤
JP2007151546A (ja) * 2005-11-11 2007-06-21 Toyobo Co Ltd 生体分子の安定化方法および組成物

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
"1.6 Kokessei no Bunriho to Hozonho, Bunshi Men'ekigaku III - Kogen. Kotai. Hotai -", 5 February 1992 (1992-02-05), pages 9 - 10 *
HAYAKAWA K. ET AL.: "Sericin no Koso Hogo Sayo", M&T GIJUTSU JOHO, no. 211, 1995, pages 4 - 5 *
HAYAKAWA K. ET AL.: "Sericin no Yuko Riyo ni Kansuru Kenkyu (3rd report) Sericin no Koso Hogo Sayo", REPORT OF KYOTO PREFECTURAL TECHNOLOGY CENTER FOR SMALL AND MEDIUM ENTERPRISES, no. 21, 1993, pages 43 - 45, XP003012795 *
ITO K. ET AL.: "Sericin ni yoru Hybridoma Saibo no Kotai Sanseino no Kojo", JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY TAIKAI KOEN YOSHISHU, vol. 2006, 5 March 2006 (2006-03-05), pages 284 *
NISHIYA Y. ET AL.: "Sericin Hydrolysate ni yoru Koso no Anteika", JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY TAIKAI KOEN YOSHISHU, vol. 2007, 5 March 2007 (2007-03-05), pages 18 *
NISHIYA Y. ET AL.: "Sericin Hydrolysate ni yoru Koso Oyobi Kotai no Anteika", ABSTRACTS OF THE ANNUAL MEETING OF THE SOCIETY FOR BIOTECHNOLOGY, JAPAN, vol. 59TH, 2 August 2007 (2007-08-02), pages 58 *
TAKADA N. ET AL.: "Sericin o Riyo shita Dobutsu Saibo ni yoru Yuyo Busshitsu Seisan", ABSTRACTS OF ANNUAL MEETING OF THE SOCIETY OF CHEMICAL ENGINEERS, JAPAN, vol. 72ND, 19 February 2007 (2007-02-19), pages 335 *
TERADA S. ET AL.: "Sericin o Riyo shita, Koritsuteki na Monoclonal Kotai Seisan", ABSTRACTS OF ANNUAL MEETING OF THE SOCIETY OF CHEMICAL ENGINEERS, JAPAN, vol. 71ST, 8 February 2006 (2006-02-08), pages 69 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8952215B2 (en) 2005-10-18 2015-02-10 Nitto Boseki Co., Ltd. Antibody-producing transgenic silkworms and methods for producing the same

Also Published As

Publication number Publication date
JP4965302B2 (ja) 2012-07-04
JP2008239512A (ja) 2008-10-09

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