WO2008110022A2 - Ensemble pompe aspirante à membrane - Google Patents

Ensemble pompe aspirante à membrane Download PDF

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Publication number
WO2008110022A2
WO2008110022A2 PCT/CH2008/000086 CH2008000086W WO2008110022A2 WO 2008110022 A2 WO2008110022 A2 WO 2008110022A2 CH 2008000086 W CH2008000086 W CH 2008000086W WO 2008110022 A2 WO2008110022 A2 WO 2008110022A2
Authority
WO
WIPO (PCT)
Prior art keywords
membrane
diaphragm
cover
frame
connecting elements
Prior art date
Application number
PCT/CH2008/000086
Other languages
German (de)
English (en)
Other versions
WO2008110022A3 (fr
Inventor
Christoph Rebsamen
Marcel Felber
Original Assignee
Medela Holding Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medela Holding Ag filed Critical Medela Holding Ag
Priority to MX2009009807A priority Critical patent/MX2009009807A/es
Priority to JP2009552984A priority patent/JP2010520962A/ja
Priority to RU2009136224/06A priority patent/RU2472967C2/ru
Priority to AU2008226308A priority patent/AU2008226308A1/en
Priority to BRPI0808211-1A priority patent/BRPI0808211A2/pt
Priority to CA002679865A priority patent/CA2679865A1/fr
Priority to US12/530,996 priority patent/US20100086419A1/en
Priority to EP08706385A priority patent/EP2129915A2/fr
Priority to CN2008800083168A priority patent/CN101636585B/zh
Publication of WO2008110022A2 publication Critical patent/WO2008110022A2/fr
Publication of WO2008110022A3 publication Critical patent/WO2008110022A3/fr

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B45/00Pumps or pumping installations having flexible working members and specially adapted for elastic fluids
    • F04B45/04Pumps or pumping installations having flexible working members and specially adapted for elastic fluids having plate-like flexible members, e.g. diaphragms
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B45/00Pumps or pumping installations having flexible working members and specially adapted for elastic fluids
    • F04B45/04Pumps or pumping installations having flexible working members and specially adapted for elastic fluids having plate-like flexible members, e.g. diaphragms
    • F04B45/047Pumps having electric drive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/06Milking pumps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/80Suction pumps
    • A61M1/82Membrane pumps, e.g. bulbs
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B49/00Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
    • F04B49/02Stopping, starting, unloading or idling control
    • F04B49/03Stopping, starting, unloading or idling control by means of valves
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B53/00Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
    • F04B53/10Valves; Arrangement of valves
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B53/00Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
    • F04B53/14Pistons, piston-rods or piston-rod connections
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F05INDEXING SCHEMES RELATING TO ENGINES OR PUMPS IN VARIOUS SUBCLASSES OF CLASSES F01-F04
    • F05BINDEXING SCHEME RELATING TO WIND, SPRING, WEIGHT, INERTIA OR LIKE MOTORS, TO MACHINES OR ENGINES FOR LIQUIDS COVERED BY SUBCLASSES F03B, F03D AND F03G
    • F05B2210/00Working fluid
    • F05B2210/10Kind or type
    • F05B2210/12Kind or type gaseous, i.e. compressible
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S417/00Pumps

Definitions

  • the invention relates to a membrane suction pump assembly according to the preamble of patent claim 1.
  • a generic membrane pump unit as part of a breast pump is known for example from US 4,964,851.
  • the breast pump has an electric motor, a motor-driven connecting rod and a pump diaphragm connected thereto.
  • the pump membrane is held in a membrane frame and forms together with a membrane cover a pumping chamber.
  • pump diaphragm and diaphragm cover are interconnected by means of a press connection, for which purpose three pins of the diaphragm frame are held in a frictional engagement in corresponding openings in the diaphragm cover.
  • US Pat. No. 7,070,400 discloses such a diaphragm pump unit of a suction pump, in which case the diaphragm has a diaphragm piston with rear recesses.
  • the membrane cover defines a space with a flat bottom portion and a conically outwardly flared circumferential sidewall. This space is covered by the diaphragm piston and forms the pumping chamber.
  • EP 0 744 180 likewise describes a membrane suction pump, which, however, is now suitable for the simultaneous use of two suction connections.
  • WO 2006/032156 shows a diaphragm pump with three housing parts, which are connected to each other with snap elements.
  • the membrane vacuum pump unit has a dimensionally stable membrane frame, a dimensionally stable integral diaphragm cover which has a pumping chamber with a bottom region and a side wall encircling the bottom region and widening outwardly away from the bottom region, and with a one-piece pump membrane comprising a membrane plate, a flexible membrane piston, at least an inlet valve flap and at least one outlet valve flap, and a one-piece pump membrane having a membrane plate, a flexible diaphragm piston and at least one inlet valve flap and at least one outlet valve flap, wherein the membrane plate between the membrane frame and the membrane lid is arranged and membrane frame, pump diaphragm and diaphragm cover means Connecting elements are connected to each other in a predetermined position to each other.
  • the membrane piston passes through the membrane frame and the diaphragm piston forms a pumping chamber with the diaphragm cover or covers its pumping chamber. According Erfrndungsconcee more than three fasteners are present, forming a material and / or positive fit.
  • the connecting elements connect membrane frame and membrane cover to one another and the pump diaphragm is held between diaphragm frame and diaphragm cover.
  • the pump membrane can be penetrated by the connecting elements or held between them.
  • connection can not solve itself or by vibration.
  • connection between the individual parts i. Frame, diaphragm and lid, solves, especially when the pump vibrates in the range of the natural vibration of the device.
  • the assembly is simplified. Usually, the assembly is done by hand. This proves to be easier in practice, if several fasteners and thus positions are available, as if three corresponding locations must be brought by hand to coincide. The risk of tilting is thereby reduced.
  • connection elements are used, which are distributed over the edge region.
  • the connecting means pins which are fixed in the receptacles. They can be glued, welded or riveted, for example. Instead of but the pins can also use form-locking elements such as snap hook, Tannenbaumschnapper and similar means.
  • the membrane lid has over its entire surface an approximately constant thickness. This also prevents distortion and deformation and increases the tightness.
  • the inventive suction pump unit can be produced inexpensively, in particular because it consists of only three parts, wherein the two dimensionally stable parts, diaphragm frame and diaphragm cover, can be produced from a plastic by injection molding and the pump membrane is preferably made by injection molding of liquid silicone.
  • This Saugpumpenaggregat is preferably used in breast pumps for pumping breast milk. However, it is also suitable for other suction pumps such as drainage pumps.
  • Figure 1 is an exploded perspective view of the Erna tion
  • FIG. 2 shows a perspective exploded view of the membrane suction pump assembly according to FIG. 1 from below;
  • Figure 3 is a perspective view of the membrane frame
  • Figure 4 is a perspective view of the membrane cover in a second embodiment
  • Figure 5 is a perspective view of a fastening pin
  • Figure 6 shows a membrane frame with electric motor in an exploded view
  • FIG. 7 shows a perspective exploded view of the membrane suction pump unit in a further embodiment.
  • the membrane suction pump assembly according to the invention according to FIG. 1 has a membrane frame 1, a pump membrane 2 and a membrane cover 3. All these parts are preferably each integrally formed.
  • Membrane frame 1 and 3 Membrande- disgust are dimensionally stable and preferably by injection molding of a plastic, for example made of thermoplastic material, such as polyester.
  • the pump diaphragm 2 is also integrally formed and injection molded. drive made of liquid silicone.
  • the membrane frame 1 has a plane-parallel base plate 10 with a round passage opening 11. At one end of the base plate 10 is perpendicular to a stop plate 16 is formed.
  • This stop plate 16 has a pump unit receptacle 19, in which a non-illustrated valve unit, for example, as disclosed in US 4,964,851, held. Within the receptacle 19, a mammal opening 18 is present in the stop plate 16, which merges on the visible in Figure 2 back in a suction nozzle 18 '.
  • an electric motor 4 shown in Figure 6 is present, which is connected via a connecting rod, not shown, with the connecting rod connection 26 described below of the pump diaphragm.
  • the stop plate 16 is provided with an Emiassö réelle 13, which is directed towards the pump diaphragm 2 out.
  • This inlet opening 13 is connected to the external environment via a connecting channel 13 '' and an inlet channel 13 'connected to it.' This can be seen in FIG.
  • the base plate 10 has on its surface a channel 10 ', which terminates in the stop plate 16 in a passage opening 10 ", which serves for mounting a vacuum regulating pin (not shown) ,
  • a circumferential first seal groove 12 is present on the underside of the base plate 10, which is visible in Figure 2, a circumferential first seal groove 12 is present. It encloses the passage opening 11, the inlet opening 13 and a groove forming an outlet channel 14. This outlet channel is disposed at the inlet opening 13 diametrically opposite side of the passage opening 11 and terminates at a side edge of the base plate 10.
  • the base plate has an upper channel end 17 in the form of a protruding nose with a U-shaped longitudinal section.
  • connecting elements are integrally formed, which project, down to the pump diaphragm out.
  • connecting elements for example snap-in elements
  • the snap-in elements are preferably formed on the outer edges of the base plate 7 is shown on the membrane frame 1.
  • Hooks 151 are formed on the peripheral end faces and mating clips 152 are fitted on the membrane cover 3.
  • the pump membrane 2 does not require any connecting elements, but is simply clamped between membrane cover 3 and membrane frame 1.
  • the pins 15, 15 ', 15 "according to the first embodiment are preferably distributed over the circumference exclusively in the edge region of the base plate 10 and outside the sealing groove 12. There are more than three pins 15, 15', 15" , In the example shown here, there are nine pins, preferably six to twelve pins are used.
  • all pins are the same length and the same thickness. However, it can also be used differently shaped pins, as is the case here.
  • the length of the pins 15, 15 ', 15 is dimensioned so that they pass through the subsequently arranged pump membrane 2 and at least partially protrude into the membrane cover 3 or preferably also fully penetrate the latter and end at its opposite surface.
  • the pins are formed on the membrane cover or that a Part of the pins on the diaphragm frame and a part are arranged on the diaphragm cover. This is shown in FIG.
  • the arranged below the base plate 10 pump diaphragm 2 has a likewise substantially plane-parallel membrane plate 20. This membrane plate
  • the membrane 20 has an approximately same base area as the base plate 10. In the central region of the membrane plate 20, this passes into a diaphragm piston 21, which protrudes the membrane plate 20 upwards to the base plate 10.
  • the membrane piston 21 is formed cap-shaped, wherein it preferably has annular recesses round.
  • the Pleuelability 26 is formed in the form of a hollow cylinder. The connecting rod can be easily inserted into this receptacle 26 and is held positively and non-positively therein.
  • the membrane plate 20 On one side of the diaphragm piston 21 there is a horseshoe-shaped inlet valve flap 23. On the opposite side of the diaphragm piston 21, the membrane plate 20 has two spaced apart likewise substantially horseshoe-shaped outlet valve flaps 24. There may also be more than one or less than two valve flaps 23, 24.
  • the membrane plate 20 has an upper sealing lip 22 which on the base plate 10 facing upper side of the diaphragm piston 21 and the valve flaps 23, 24 surrounds, is closed in itself and projects upwards.
  • membrane plate 20 on its the diaphragm cover 3 facing bottom on a circumferential lower sealing lip 28, which also membrane piston
  • valve flaps 23, 24 surrounds and protrudes downwards.
  • the two sealing lips 22, 28 are congruent.
  • sealing lips and sealing grooves could be present and the membrane cover and / or the membrane frame are provided with a corresponding sealing lip or edge.
  • a protruding lug 27 is formed, which protrudes the edge, but otherwise aligned with the top and bottom of the plate 20.
  • first and second fastening holes 25, 25 ' which diameters preferably correspond to the associated pins 15, 15', 15 "of the base plate 10 or are slightly larger.
  • the membrane cover 3 has a cover plate 30, whose upper side directed towards the pump membrane 2 is also substantially planar. Its bottom, however, is structured, as described below. In the middle of the cover plate 30, a pumping chamber 31 is formed. This has a bottom area at the same level as the surface of the remaining cover plate 30 and a circular peripheral raised side wall 36, wherein the side wall is formed upwardly and outwardly inclined, so that the opening widens above the bottom area.
  • the side wall 36 may be straight obliquely or, as shown here, curved.
  • the side wall 36 is pierced by at least one inlet channel, in this case three mutually parallel inlet channels 33 '.
  • These channels 33 come from an inlet basin 33, which is formed as a depression in the cover plate 30 and end in the bottom area spaced from the side wall 36.
  • Pumping chamber 31, inlet basin 33 and the inlet and outlet channels 33 ', 34 are surrounded by a completely circumferential second sealing groove 32.
  • a protruding nose is formed, which forms a lower channel end 37 with upstanding side walls.
  • This lower channel end 37 forms the counterpart to the upper channel end 17 and thus preferably has a U-shaped longitudinal section.
  • the above-mentioned projecting nose 27 of the pump diaphragm 2 is dimensioned in size so that it corresponds to the Grundfiä- che of the channel terminations 17, 37 and is held therein.
  • the underside of the cover plate 30 is formed as a negative to the formed in the top of the cover plate elements structured.
  • the cover plate 30 has an approximately constant over the entire or over a large area of the base surface thickness. However, this does not apply everywhere. For example, this does not apply in the area of the reinforcing webs between the bushings or between any other elevations in the underside.
  • This type of structured cover plate can also be used in Saugpumpenaggregaten whose connecting elements frictionally or non-positively connect the individual parts.
  • the pump membrane 2 or its membrane plate 20 is now clamped between the base plate 10 of the membrane frame 1 and the cover plate 30 of the membrane plate 3.
  • the membrane piston 21 passes through the fürgangsöffhung 11 and can move in accordance with the engine up and down.
  • the diaphragm piston 21 covers the Pumping chamber 31 and, since the outer diameter of the diaphragm piston 21 is equal to or greater than the outer diameter of the side wall 36 of the pumping chamber 31, seals the chamber 31 to the inlet and outlet ports 33 ', 34 from.
  • the fastening pins 15, 15 ', 15 pass through the fastening holes 25, 25' of the pump diaphragm 2 and are inserted in a form-fitting manner into the retaining sleeves 35, 35 ', 35" of the diaphragm cover 3.
  • they are glued therein by means of an adhesive or they are otherwise materially or materially connected.
  • they can be ultrasonically welded, vibration-welded, welded at high frequency or ultrasonically riveted.
  • the inlet opening 13 now lies above the inlet valve flap 23 and above the inlet basin 33.
  • the outlet channel 14 of the membrane frame 1 lies above the outlet valve flaps 24 and these over the outlet channels 34 of the membrane cover.
  • the upper and lower sealing lips 22, 28 lie in the first and the second sealing groove 12, 32 and thus seal the respectively enclosed thereby regions to the outside.
  • the side walls of the lower channel termination 37 resiliently surround the side walls of the upper channel termination 17 and thus form a tight form and adhesion.
  • the nose 27 of the pump diaphragm 2 rests on the lower channel end 37.
  • the diaphragm piston 21 passes through the through opening 11 of the base plate 10 in the assembled state of the unit. LIST OF REFERENCE NUMBERS

Abstract

Un ensemble pompe aspirante à membrane comprend un support de membrane (1) indéformable, un couvercle de membrane (3) en une seule pièce, indéformable, qui présente une chambre de pompe (31) ayant une zone de fond et une paroi latérale (36) entourant la zone de fond et s'étendant de ladite zone de fond vers l'extérieur, et une membrane de pompe (2) en une seule pièce, laquelle comporte une plaque de membrane (20), un piston de membrane (21) souple, au moins un clapet de soupape d'admission (23) et au moins un clapet de soupape de refoulement (24). La plaque de membrane (20) est disposée entre le support de membrane (1) et le couvercle de membrane (3), le support de membrane (1), la membrane de pompe (2) et le couvercle de membrane (3) étant reliés entre eux, en position prédéterminée, au moyen d'éléments de raccordement (15, 15', 15''). Le piston de membrane (21) traverse le support de membrane (1), ledit piston de membrane (21) recouvrant une chambre de pompe (31) du couvercle de membrane (3). L'invention est caractérisée en ce qu'il est prévu plus de trois éléments de raccordement (15, 15', 15''), et en ce que ceux-ci forment une liaison de matière et/ou une complémentarité de forme.
PCT/CH2008/000086 2007-03-13 2008-03-04 Ensemble pompe aspirante à membrane WO2008110022A2 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
MX2009009807A MX2009009807A (es) 2007-03-13 2008-03-04 Unidad de bomba aspirante de diafragma.
JP2009552984A JP2010520962A (ja) 2007-03-13 2008-03-04 膜吸引ポンプユニット
RU2009136224/06A RU2472967C2 (ru) 2007-03-13 2008-03-04 Узел мембранного отсасывателя
AU2008226308A AU2008226308A1 (en) 2007-03-13 2008-03-04 Membrane suction pump unit
BRPI0808211-1A BRPI0808211A2 (pt) 2007-03-13 2008-03-04 "unidade de bomba de diafragma a vácuo"
CA002679865A CA2679865A1 (fr) 2007-03-13 2008-03-04 Ensemble pompe aspirante a membrane
US12/530,996 US20100086419A1 (en) 2007-03-13 2008-03-04 Membrane Suction Pump Unit
EP08706385A EP2129915A2 (fr) 2007-03-13 2008-03-04 Ensemble pompe aspirante à membrane
CN2008800083168A CN101636585B (zh) 2007-03-13 2008-03-04 隔膜真空泵单元

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH4052007 2007-03-13
CH405/07 2007-03-13

Publications (2)

Publication Number Publication Date
WO2008110022A2 true WO2008110022A2 (fr) 2008-09-18
WO2008110022A3 WO2008110022A3 (fr) 2008-11-06

Family

ID=38910890

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CH2008/000086 WO2008110022A2 (fr) 2007-03-13 2008-03-04 Ensemble pompe aspirante à membrane

Country Status (12)

Country Link
US (1) US20100086419A1 (fr)
EP (1) EP2129915A2 (fr)
JP (1) JP2010520962A (fr)
KR (1) KR20090118065A (fr)
CN (1) CN101636585B (fr)
AU (1) AU2008226308A1 (fr)
BR (1) BRPI0808211A2 (fr)
CA (1) CA2679865A1 (fr)
MX (1) MX2009009807A (fr)
RU (1) RU2472967C2 (fr)
TW (1) TW200900586A (fr)
WO (1) WO2008110022A2 (fr)

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US9227000B2 (en) 2006-09-28 2016-01-05 Smith & Nephew, Inc. Portable wound therapy system
US9427505B2 (en) 2012-05-15 2016-08-30 Smith & Nephew Plc Negative pressure wound therapy apparatus
CH711436A1 (de) * 2015-08-20 2017-02-28 Medmix Systems Ag Membranpumpe mit Medientrennung.
US10682446B2 (en) 2014-12-22 2020-06-16 Smith & Nephew Plc Dressing status detection for negative pressure wound therapy
US11027051B2 (en) 2010-09-20 2021-06-08 Smith & Nephew Plc Pressure control apparatus

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US9084845B2 (en) 2011-11-02 2015-07-21 Smith & Nephew Plc Reduced pressure therapy apparatuses and methods of using same
EP3068461B1 (fr) * 2013-11-15 2021-04-14 Ivenix, Inc. Chambre de pompe comprenant des modifications de surface interne
CN104712535B (zh) * 2014-11-05 2016-11-16 东莞市天昶机电制造有限公司 一种用于医用雾化器的消音压缩机
JP2016200014A (ja) * 2015-04-07 2016-12-01 住友ゴム工業株式会社 ダイアフラムポンプ
CN109611315B (zh) * 2019-01-25 2023-09-26 东莞市简爱母婴用品有限公司 泵阀一体化的真空泵及吸奶器

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Cited By (18)

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Publication number Priority date Publication date Assignee Title
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US9642955B2 (en) 2006-09-28 2017-05-09 Smith & Nephew, Inc. Portable wound therapy system
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RU2472967C2 (ru) 2013-01-20
EP2129915A2 (fr) 2009-12-09
MX2009009807A (es) 2009-09-24
CN101636585A (zh) 2010-01-27
RU2009136224A (ru) 2011-04-20
US20100086419A1 (en) 2010-04-08
BRPI0808211A2 (pt) 2014-07-01
AU2008226308A1 (en) 2008-09-18
CA2679865A1 (fr) 2008-09-18
JP2010520962A (ja) 2010-06-17
CN101636585B (zh) 2012-02-22
TW200900586A (en) 2009-01-01
WO2008110022A3 (fr) 2008-11-06
KR20090118065A (ko) 2009-11-17

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