WO2008105436A1 - 腫瘍壊死因子－α抑制剤およびプロスタグランジン合成酵素－２抑制剤 - Google Patents

腫瘍壊死因子－α抑制剤およびプロスタグランジン合成酵素－２抑制剤 Download PDF

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Publication number
WO2008105436A1
WO2008105436A1 PCT/JP2008/053352 JP2008053352W WO2008105436A1 WO 2008105436 A1 WO2008105436 A1 WO 2008105436A1 JP 2008053352 W JP2008053352 W JP 2008053352W WO 2008105436 A1 WO2008105436 A1 WO 2008105436A1
Authority
WO
WIPO (PCT)
Prior art keywords
inhibitor
necrosis factor
tumor necrosis
plant
prostaglandin synthase
Prior art date
Application number
PCT/JP2008/053352
Other languages
English (en)
French (fr)
Inventor
Yoko Aniya
Original Assignee
University Of The Ryukyus
Lequio Pharma Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of The Ryukyus, Lequio Pharma Co., Ltd. filed Critical University Of The Ryukyus
Priority to JP2009501261A priority Critical patent/JPWO2008105436A1/ja
Publication of WO2008105436A1 publication Critical patent/WO2008105436A1/ja

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Emergency Medicine (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

　沖縄に生育する植物中から優れた薬効や機能性を有するものを見出し、このものが含む有効成分を取りだして医薬あるいは機能性食品等として利用することを目的とし、ベニバナボロギクの抽出物を有効成分とする腫瘍壊死因子－α抑制剤およびプロスタグランジン合成酵素－２抑制剤を提供する。
PCT/JP2008/053352 2007-02-28 2008-02-27 腫瘍壊死因子－α抑制剤およびプロスタグランジン合成酵素－２抑制剤 WO2008105436A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009501261A JPWO2008105436A1 (ja) 2007-02-28 2008-02-27 腫瘍壊死因子−α抑制剤およびプロスタグランジン合成酵素−２抑制剤

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007049885 2007-02-28
JP2007-049885 2007-02-28

Publications (1)

Publication Number Publication Date
WO2008105436A1 true WO2008105436A1 (ja) 2008-09-04

Family

ID=39721261

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/053352 WO2008105436A1 (ja) 2007-02-28 2008-02-27 腫瘍壊死因子－α抑制剤およびプロスタグランジン合成酵素－２抑制剤

Country Status (3)

Country Link
JP (1) JPWO2008105436A1 (ja)
TW (1) TW200904463A (ja)
WO (1) WO2008105436A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104208114A (zh) * 2013-06-04 2014-12-17 中央研究院 富含半乳糖脂的植物萃取物及其用途
DE112015007252T5 (de) 2015-12-31 2018-09-27 Dcb-Usa Llc Verfahren zur herstellung eines crassocephalum crepidioides extrakts, damithergestellter extrakt und verwendung des extrakts

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003026694A (ja) * 2001-07-17 2003-01-29 Tetsuya Toyokawa 二糖類分解酵素阻害物質
JP2004532811A (ja) * 2000-12-15 2004-10-28 ファルマシア・コーポレーション 食用植物抽出物による選択的ｃｏｘ−２阻害

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004532811A (ja) * 2000-12-15 2004-10-28 ファルマシア・コーポレーション 食用植物抽出物による選択的ｃｏｘ−２阻害
JP2003026694A (ja) * 2001-07-17 2003-01-29 Tetsuya Toyokawa 二糖類分解酵素阻害物質

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
TAKAMATSU R. ET AL.: "Effect of Crassocephalum crepidioides on inducible nitric oxide synthase", J. TOXCIOL. SCI., vol. 30, no. SUPPL., 2005, pages S145 + ABSTR. NO. P-49, XP003022390 *
TAKAMATSU R. ET AL.: "Okinawasan Yakuso Benibanaborogiku no Yudogata Issanka Chisso Gosei Koso (iNOS) ni Oyobosu Eikyo", ANNUAL MEETING OF THE JAPANESE SOCIETY OF TOXICOLOGY PROGRAM. YOSHISHU 32 KAI, 2005, pages 221 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104208114A (zh) * 2013-06-04 2014-12-17 中央研究院 富含半乳糖脂的植物萃取物及其用途
EP2810651B1 (en) * 2013-06-04 2019-09-11 Academia Sinica Galactolipids-enriched plant extracts and the uses thereof
DE112015007252T5 (de) 2015-12-31 2018-09-27 Dcb-Usa Llc Verfahren zur herstellung eines crassocephalum crepidioides extrakts, damithergestellter extrakt und verwendung des extrakts
US10980853B2 (en) 2015-12-31 2021-04-20 Development Center For Biotechnology Process for preparing a crassocephalum crepidioides extract, extract prepared thereby and use of the extract

Also Published As

Publication number Publication date
JPWO2008105436A1 (ja) 2010-06-03
TW200904463A (en) 2009-02-01

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