WO2009007964A3 - Pectin methyl esterase-inhibiting polyphenolic flavonoids and use thereof - Google Patents

Pectin methyl esterase-inhibiting polyphenolic flavonoids and use thereof Download PDF

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Publication number
WO2009007964A3
WO2009007964A3 PCT/IL2008/000944 IL2008000944W WO2009007964A3 WO 2009007964 A3 WO2009007964 A3 WO 2009007964A3 IL 2008000944 W IL2008000944 W IL 2008000944W WO 2009007964 A3 WO2009007964 A3 WO 2009007964A3
Authority
WO
WIPO (PCT)
Prior art keywords
inhibit
polyphenolic flavonoids
methyl esterase
inhibiting
pectin methyl
Prior art date
Application number
PCT/IL2008/000944
Other languages
French (fr)
Other versions
WO2009007964A2 (en
Inventor
Irit Sagi
Kristin Lewis
Original Assignee
Yeda Research And Development Co. Ltd.
President And Fellows Of Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research And Development Co. Ltd., President And Fellows Of Harvard College filed Critical Yeda Research And Development Co. Ltd.
Publication of WO2009007964A2 publication Critical patent/WO2009007964A2/en
Publication of WO2009007964A3 publication Critical patent/WO2009007964A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3544—Organic compounds containing hetero rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
    • A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08—Magnoliopsida [dicotyledons]

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Microbiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pest Control & Pesticides (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to compositions comprising polyphenolic flavonoids in general and to polyphenolic flavonoids extracted from green tea in particular, useful to prevent or retard pectin degradation. Green tea polyphenols, especially catechins are now shown to inhibit the cell wall degrading enzyme pectin methyl esterase. The invention further provides methods of using these enzyme inhibitors, including agricultural uses to inhibit plant parasites and other plant pathogens, particularly to inhibit parasitic plants in or on a host plant, and as additives to processed foods and juices.
PCT/IL2008/000944 2007-07-09 2008-07-09 Pectin methyl esterase-inhibiting polyphenolic flavonoids and use thereof WO2009007964A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94849207P 2007-07-09 2007-07-09
US60/948,492 2007-07-09

Publications (2)

Publication Number Publication Date
WO2009007964A2 WO2009007964A2 (en) 2009-01-15
WO2009007964A3 true WO2009007964A3 (en) 2010-03-18

Family

ID=39791551

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2008/000944 WO2009007964A2 (en) 2007-07-09 2008-07-09 Pectin methyl esterase-inhibiting polyphenolic flavonoids and use thereof

Country Status (1)

Country Link
WO (1) WO2009007964A2 (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014342963A1 (en) 2013-11-01 2015-11-26 Thomas T. Yamashita Compositions for controlling plant parasitic nematodes and methods for using same
BE1027622B1 (en) * 2019-10-05 2021-05-04 Denis Mbonimpa SX-PYR PESTICIDE SYNERGIST
CN113303421B (en) * 2021-06-16 2022-04-26 中国农业大学 Method for inhibiting PME (polymethylene oxide) and/or PPO (polyphenylene oxide) activity in fruit and vegetable products by ultrahigh pressure synergistic EGCG (epigallocatechin gallate)
GB202116273D0 (en) * 2021-11-11 2021-12-29 Seegrow Solutions Ltd Ozone compositions
WO2023183869A1 (en) * 2022-03-24 2023-09-28 Virginia Tech Intellectual Properties Inc. Methods for preventing bacterial infection of plant seeds
CN114560961A (en) * 2022-04-21 2022-05-31 广西农业职业技术大学 Method for extracting low-molecular-weight pectin from banana peel
CN114831292B (en) * 2022-05-26 2023-08-11 华中农业大学 Method for improving texture of traditional pickled kohlrabi

Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2228434A1 (en) * 1973-05-08 1974-12-06 Delpech Lucien Fungicides for treatment of plants or wood - contg. a natural or synthetic phenol
EP0427894A1 (en) * 1989-11-13 1991-05-22 Mitsui Norin Co., Ltd. Expellent for land and aquatic shells
JPH03200781A (en) * 1989-12-28 1991-09-02 Kikkoman Corp Production of proanthocyanidin
JPH05139924A (en) * 1991-11-25 1993-06-08 Itouen:Kk Plant disease injury controlling agent containing natural ingredient as active ingredient
WO1994013141A1 (en) * 1992-12-16 1994-06-23 Elf Atochem S.A. Polyphenol-based insecticide compositions
WO1997032947A1 (en) * 1996-03-05 1997-09-12 Comiter Trading & Services S.R.L. A product based on olive oil, enriched and supplemented with antioxidants
EP0795272A2 (en) * 1996-03-12 1997-09-17 Xeda International Fruit and vegetable treatment process
WO1998058540A1 (en) * 1997-06-23 1998-12-30 Schuer Joerg Peter Additive for improving the storage life of and/or stabilising microbially perishable products
WO1999063048A1 (en) * 1998-06-04 1999-12-09 Mircea Leonte Beverages with ecological-biological properties and process for the preparation thereof
JP2000212093A (en) * 1998-11-17 2000-08-02 Ito En Ltd Antifungal agent
DE19917836A1 (en) * 1999-04-20 2000-10-26 Cs Dental Gmbh Natural preservative, effective against bacteria, fungi, parasites and viruses and useful e.g. in cosmetics, foods or water treatment, comprises citrus fruit extract or diphenolbenzene complex
WO2001013727A1 (en) * 1999-08-25 2001-03-01 Schuer Joerg Plant protection
WO2003056916A2 (en) * 2001-07-20 2003-07-17 Colorado State University Research Foundation Herbicidal and bacteriostatic compounds from centaurea maculosa
US6616952B1 (en) * 2000-11-17 2003-09-09 Roseberg Investments, Inc. Organic fungicide
US20030186442A1 (en) * 2002-03-27 2003-10-02 Indra Sandal Efficient method of preventing growth of microbial genetic transformant after transformation
EP1504754A1 (en) * 2002-05-10 2005-02-09 Suntory Limited Gallocatechin gallate-containing composition
US20050074508A1 (en) * 2002-12-03 2005-04-07 Ricardo San Martin Compositions and methods based on exracts of quillaja saponaria molina for controlling nematodes
WO2005102059A1 (en) * 2004-04-23 2005-11-03 Asahi Breweries, Ltd. Control agent for disease caused by plant filamentous fungus, method of controlling disease caused by plant filamentous fungus and fertilizer therefor
EP1849779A1 (en) * 2005-01-26 2007-10-31 Suntory Limited Esterified catechin, process for producing the same, food and drink or cosmetic containing the same
EP1867230A2 (en) * 2006-05-29 2007-12-19 Nor-Natur ApS A natural product having a fungus inhibiting effect on specific fungal pathogens and a growth promoting effect for improving plant production

Patent Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2228434A1 (en) * 1973-05-08 1974-12-06 Delpech Lucien Fungicides for treatment of plants or wood - contg. a natural or synthetic phenol
EP0427894A1 (en) * 1989-11-13 1991-05-22 Mitsui Norin Co., Ltd. Expellent for land and aquatic shells
JPH03200781A (en) * 1989-12-28 1991-09-02 Kikkoman Corp Production of proanthocyanidin
JPH05139924A (en) * 1991-11-25 1993-06-08 Itouen:Kk Plant disease injury controlling agent containing natural ingredient as active ingredient
WO1994013141A1 (en) * 1992-12-16 1994-06-23 Elf Atochem S.A. Polyphenol-based insecticide compositions
WO1997032947A1 (en) * 1996-03-05 1997-09-12 Comiter Trading & Services S.R.L. A product based on olive oil, enriched and supplemented with antioxidants
EP0795272A2 (en) * 1996-03-12 1997-09-17 Xeda International Fruit and vegetable treatment process
WO1998058540A1 (en) * 1997-06-23 1998-12-30 Schuer Joerg Peter Additive for improving the storage life of and/or stabilising microbially perishable products
WO1999063048A1 (en) * 1998-06-04 1999-12-09 Mircea Leonte Beverages with ecological-biological properties and process for the preparation thereof
JP2000212093A (en) * 1998-11-17 2000-08-02 Ito En Ltd Antifungal agent
DE19917836A1 (en) * 1999-04-20 2000-10-26 Cs Dental Gmbh Natural preservative, effective against bacteria, fungi, parasites and viruses and useful e.g. in cosmetics, foods or water treatment, comprises citrus fruit extract or diphenolbenzene complex
WO2001013727A1 (en) * 1999-08-25 2001-03-01 Schuer Joerg Plant protection
US6616952B1 (en) * 2000-11-17 2003-09-09 Roseberg Investments, Inc. Organic fungicide
WO2003056916A2 (en) * 2001-07-20 2003-07-17 Colorado State University Research Foundation Herbicidal and bacteriostatic compounds from centaurea maculosa
US20030186442A1 (en) * 2002-03-27 2003-10-02 Indra Sandal Efficient method of preventing growth of microbial genetic transformant after transformation
EP1504754A1 (en) * 2002-05-10 2005-02-09 Suntory Limited Gallocatechin gallate-containing composition
US20050074508A1 (en) * 2002-12-03 2005-04-07 Ricardo San Martin Compositions and methods based on exracts of quillaja saponaria molina for controlling nematodes
WO2005102059A1 (en) * 2004-04-23 2005-11-03 Asahi Breweries, Ltd. Control agent for disease caused by plant filamentous fungus, method of controlling disease caused by plant filamentous fungus and fertilizer therefor
EP1849779A1 (en) * 2005-01-26 2007-10-31 Suntory Limited Esterified catechin, process for producing the same, food and drink or cosmetic containing the same
EP1867230A2 (en) * 2006-05-29 2007-12-19 Nor-Natur ApS A natural product having a fungus inhibiting effect on specific fungal pathogens and a growth promoting effect for improving plant production

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BAIS H P ET AL: "Enantiomeric-dependent phytotoxic and antimicrobial activity of (+)-catechin. A rhizosecreted racemic mixture from spotted knapweed", PLANT PHYSIOLOGY, AMERICAN SOCIETY OF PLANT PHYSIOLOGISTS, ROCKVILLE, MD, US, vol. 128, 1 April 2002 (2002-04-01), pages 1173 - 1179, XP002969206, ISSN: 0032-0889 *
DATABASE WPI Week 199141, Derwent World Patents Index; AN 1991-300280, XP002149838 *
DATABASE WPI Week 199327, Derwent World Patents Index; AN 1993-216621, XP002186133 *
DATABASE WPI Week 200055, Derwent World Patents Index; AN 2000-582018, XP002469404 *
DATABASE WPI Week 200577, Derwent World Patents Index; AN 2005-758994, XP002558829 *

Also Published As

Publication number Publication date
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