WO2008103068A3 - Способ получения 2-aнилинoпиpимидинoв или их солей - Google Patents
Способ получения 2-aнилинoпиpимидинoв или их солей Download PDFInfo
- Publication number
- WO2008103068A3 WO2008103068A3 PCT/RU2008/000037 RU2008000037W WO2008103068A3 WO 2008103068 A3 WO2008103068 A3 WO 2008103068A3 RU 2008000037 W RU2008000037 W RU 2008000037W WO 2008103068 A3 WO2008103068 A3 WO 2008103068A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- producing
- anilinopyrimidines
- salts
- novel
- treating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Изобретение
относится к
новому способу
получения производных
2- анилинопиримидинов
и
их солей, которые
могут найти
применение
для приготовления
лекарственных
средств
при
лечении различных
заболеваний,
в частности
соединений
с противоопухолевой
активностью.
Согласно
предлагаемому
способу может
быть получен
также иматиниб,
известный как
средство
для
лечения лейкемии,
церебральной
ишемии, сосудистого
стеноза. Способ
позволяет
получить
также новые
промежуточные
продукты и
новые производные
2- анилинопиримидинов.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2007106105 | 2007-02-20 | ||
RU2007106105/04A RU2329260C1 (ru) | 2007-02-20 | 2007-02-20 | Способ получения 2-анилинопиримидинов или их солей (варианты) |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008103068A2 WO2008103068A2 (ru) | 2008-08-28 |
WO2008103068A3 true WO2008103068A3 (ru) | 2008-10-16 |
Family
ID=39710618
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/RU2008/000037 WO2008103068A2 (ru) | 2007-02-20 | 2008-01-25 | Способ получения 2-aнилинoпиpимидинoв или их солей |
Country Status (2)
Country | Link |
---|---|
RU (1) | RU2329260C1 (ru) |
WO (1) | WO2008103068A2 (ru) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011038204A1 (en) | 2009-09-25 | 2011-03-31 | N30 Pharmaceuticals, Llc | Novel dihydropyrimidin-2(1h)-one compounds as s-nitrosoglutathione reductase inhibitors |
WO2012039718A1 (en) | 2010-09-24 | 2012-03-29 | N30 Pharmaceuticals, Llc | Novel dihydropyrimidin-2(1h)-one compounds as neurokinin-3 receptor antagonists |
CN102796110B (zh) * | 2011-05-23 | 2016-03-30 | 复旦大学 | 苯胺嘧啶化合物及其制备方法和用途 |
RU2486180C1 (ru) * | 2011-11-02 | 2013-06-27 | Общество с ограниченной ответственностью "ТехноХим" (ООО "ТехноХим") | Способ получения 2-ариламино-4-гетарилпиримидинов |
WO2013120852A1 (en) | 2012-02-13 | 2013-08-22 | Grindeks, A Joint Stock Company | Intermediates for a novel process of preparing imatinib and related tyrosine kinase inhibitors |
AU2016261823B2 (en) * | 2015-05-12 | 2020-12-10 | Championx Usa Inc. | Crosslinker composition including synthetic layered silicate |
CN105801559B (zh) * | 2016-04-28 | 2019-03-01 | 北京化工大学 | 4-甲基-3-[[4-(3-吡啶基)-2-嘧啶基]氨基]苯甲酸乙酯的制备方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0812832A1 (en) * | 1996-04-10 | 1997-12-17 | Rohm And Haas Company | Improved process for pyrimidinone compounds |
RU2125992C1 (ru) * | 1992-04-03 | 1999-02-10 | Новартис Аг | Производные n-фенил-2-пиримидинамина или их соли и фармацевтическая композиция на их основе, обладающая противоопухолевой активностью |
RU2005129100A (ru) * | 2003-02-18 | 2006-06-10 | Сипла Лтд. (In) | Способ получения иматиниба, и иматиниб, полученный данным способом |
-
2007
- 2007-02-20 RU RU2007106105/04A patent/RU2329260C1/ru active IP Right Revival
-
2008
- 2008-01-25 WO PCT/RU2008/000037 patent/WO2008103068A2/ru active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2125992C1 (ru) * | 1992-04-03 | 1999-02-10 | Новартис Аг | Производные n-фенил-2-пиримидинамина или их соли и фармацевтическая композиция на их основе, обладающая противоопухолевой активностью |
EP0812832A1 (en) * | 1996-04-10 | 1997-12-17 | Rohm And Haas Company | Improved process for pyrimidinone compounds |
RU2005129100A (ru) * | 2003-02-18 | 2006-06-10 | Сипла Лтд. (In) | Способ получения иматиниба, и иматиниб, полученный данным способом |
Also Published As
Publication number | Publication date |
---|---|
RU2329260C1 (ru) | 2008-07-20 |
WO2008103068A2 (ru) | 2008-08-28 |
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