WO2008096790A1 - 腫瘍マーカー糖鎖の解析及び利用 - Google Patents
腫瘍マーカー糖鎖の解析及び利用 Download PDFInfo
- Publication number
- WO2008096790A1 WO2008096790A1 PCT/JP2008/051961 JP2008051961W WO2008096790A1 WO 2008096790 A1 WO2008096790 A1 WO 2008096790A1 JP 2008051961 W JP2008051961 W JP 2008051961W WO 2008096790 A1 WO2008096790 A1 WO 2008096790A1
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- WO
- WIPO (PCT)
- Prior art keywords
- sugar chain
- analysis
- tissue
- tumor marker
- tumor
- Prior art date
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/02—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates involving antibodies to sugar part of glycoproteins
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
極めて少量しか手に入らないような組織を出発材料として、腫瘍マーカーである糖鎖を検出及び/又は同定する迅速で且つ簡便な技術の開発。
腫瘍組織(又は腫瘍細胞)から糖鎖を簡単な操作で且つ大量に取得できる、糖タンパク質からの糖鎖の調製方法を適用して、糖鎖含有試料を取得して、それに含有される糖鎖成分を詳細に解析し、得られた結果を、同様に正常組織(又は正常細胞)から得られた糖鎖含有試料について得られた結果と比較して、含有される糖鎖成分の差異を検出する。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008557143A JPWO2008096790A1 (ja) | 2007-02-07 | 2008-02-06 | 腫瘍マーカー糖鎖の解析及び利用 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007028238 | 2007-02-07 | ||
JP2007-028238 | 2007-02-07 |
Publications (1)
Publication Number | Publication Date |
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WO2008096790A1 true WO2008096790A1 (ja) | 2008-08-14 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PCT/JP2008/051961 WO2008096790A1 (ja) | 2007-02-07 | 2008-02-06 | 腫瘍マーカー糖鎖の解析及び利用 |
Country Status (2)
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JP (1) | JPWO2008096790A1 (ja) |
WO (1) | WO2008096790A1 (ja) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011040008A1 (ja) * | 2009-09-30 | 2011-04-07 | 国立大学法人北海道大学 | 糖鎖分析による婦人科がんの診断方法 |
WO2015186690A1 (ja) * | 2014-06-03 | 2015-12-10 | 学校法人北里研究所 | 無水ヒドラジンによる、糖タンパク質からのO-結合型糖鎖のβ脱離反応における、脱離した糖鎖の分解抑制剤、キット及び方法 |
JP2017067677A (ja) * | 2015-10-01 | 2017-04-06 | 住友ベークライト株式会社 | 標識糖の精製物を調製する方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH03154866A (ja) * | 1989-11-14 | 1991-07-02 | Joko:Kk | 腫瘍マーカーの分析方法 |
WO2006022114A1 (ja) * | 2004-08-27 | 2006-03-02 | Niigata University | 脳腫瘍の検出方法及びそれに用いる脳腫瘍の検出物質、並びに医薬組成物 |
WO2007011055A1 (ja) * | 2005-07-19 | 2007-01-25 | Otsuka Chemical Co., Ltd. | 糖鎖誘導体の製造方法、構造解析方法、及び糖鎖誘導体 |
JP2007045889A (ja) * | 2005-08-08 | 2007-02-22 | Kagawa Univ | 糖タンパク質からの糖鎖の調製方法 |
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2008
- 2008-02-06 WO PCT/JP2008/051961 patent/WO2008096790A1/ja active Application Filing
- 2008-02-06 JP JP2008557143A patent/JPWO2008096790A1/ja active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH03154866A (ja) * | 1989-11-14 | 1991-07-02 | Joko:Kk | 腫瘍マーカーの分析方法 |
WO2006022114A1 (ja) * | 2004-08-27 | 2006-03-02 | Niigata University | 脳腫瘍の検出方法及びそれに用いる脳腫瘍の検出物質、並びに医薬組成物 |
WO2007011055A1 (ja) * | 2005-07-19 | 2007-01-25 | Otsuka Chemical Co., Ltd. | 糖鎖誘導体の製造方法、構造解析方法、及び糖鎖誘導体 |
JP2007045889A (ja) * | 2005-08-08 | 2007-02-22 | Kagawa Univ | 糖タンパク質からの糖鎖の調製方法 |
Non-Patent Citations (2)
Title |
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HARADA Y. ET AL.: "Shuyo Marker Nyugan", JAPANESE JOURNAL OF CANCER AND CHEMOTHERAPY, vol. 28, no. 7, 15 July 2001 (2001-07-15), pages 1035 - 1040 * |
KOBATA A.: "Keishitsumaku Naizaisei Totanpakushitsu no N-ketsugogata Tosa no Tokucho to sono Gansei Henka", ANNUAL REPORT OF THE NOGUCHI INSTITUTE, no. 49, 2006, pages 4 - 20, XP008153741 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011040008A1 (ja) * | 2009-09-30 | 2011-04-07 | 国立大学法人北海道大学 | 糖鎖分析による婦人科がんの診断方法 |
WO2015186690A1 (ja) * | 2014-06-03 | 2015-12-10 | 学校法人北里研究所 | 無水ヒドラジンによる、糖タンパク質からのO-結合型糖鎖のβ脱離反応における、脱離した糖鎖の分解抑制剤、キット及び方法 |
JP2017067677A (ja) * | 2015-10-01 | 2017-04-06 | 住友ベークライト株式会社 | 標識糖の精製物を調製する方法 |
Also Published As
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JPWO2008096790A1 (ja) | 2010-05-27 |
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