WO2008096790A1 - 腫瘍マーカー糖鎖の解析及び利用 - Google Patents

腫瘍マーカー糖鎖の解析及び利用 Download PDF

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Publication number
WO2008096790A1
WO2008096790A1 PCT/JP2008/051961 JP2008051961W WO2008096790A1 WO 2008096790 A1 WO2008096790 A1 WO 2008096790A1 JP 2008051961 W JP2008051961 W JP 2008051961W WO 2008096790 A1 WO2008096790 A1 WO 2008096790A1
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WO
WIPO (PCT)
Prior art keywords
sugar chain
analysis
tissue
tumor marker
tumor
Prior art date
Application number
PCT/JP2008/051961
Other languages
English (en)
French (fr)
Inventor
Shin-Ichi Nakakita
Akira Yamauchi
Keisuke Takeshita
Original Assignee
Galpharma Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Galpharma Co., Ltd. filed Critical Galpharma Co., Ltd.
Priority to JP2008557143A priority Critical patent/JPWO2008096790A1/ja
Publication of WO2008096790A1 publication Critical patent/WO2008096790A1/ja

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/02—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates involving antibodies to sugar part of glycoproteins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

　極めて少量しか手に入らないような組織を出発材料として、腫瘍マーカーである糖鎖を検出及び／又は同定する迅速で且つ簡便な技術の開発。 　腫瘍組織（又は腫瘍細胞）から糖鎖を簡単な操作で且つ大量に取得できる、糖タンパク質からの糖鎖の調製方法を適用して、糖鎖含有試料を取得して、それに含有される糖鎖成分を詳細に解析し、得られた結果を、同様に正常組織（又は正常細胞）から得られた糖鎖含有試料について得られた結果と比較して、含有される糖鎖成分の差異を検出する。
PCT/JP2008/051961 2007-02-07 2008-02-06 腫瘍マーカー糖鎖の解析及び利用 WO2008096790A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008557143A JPWO2008096790A1 (ja) 2007-02-07 2008-02-06 腫瘍マーカー糖鎖の解析及び利用

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-028238 2007-02-07
JP2007028238 2007-02-07

Publications (1)

Publication Number Publication Date
WO2008096790A1 true WO2008096790A1 (ja) 2008-08-14

Family

ID=39681696

Family Applications (1)

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PCT/JP2008/051961 WO2008096790A1 (ja) 2007-02-07 2008-02-06 腫瘍マーカー糖鎖の解析及び利用

Country Status (2)

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JP (1) JPWO2008096790A1 (ja)
WO (1) WO2008096790A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011040008A1 (ja) * 2009-09-30 2011-04-07 国立大学法人北海道大学 糖鎖分析による婦人科がんの診断方法
WO2015186690A1 (ja) * 2014-06-03 2015-12-10 学校法人北里研究所 無水ヒドラジンによる、糖タンパク質からのＯ－結合型糖鎖のβ脱離反応における、脱離した糖鎖の分解抑制剤、キット及び方法
JP2017067677A (ja) * 2015-10-01 2017-04-06 住友ベークライト株式会社 標識糖の精製物を調製する方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03154866A (ja) * 1989-11-14 1991-07-02 Joko:Kk 腫瘍マーカーの分析方法
WO2006022114A1 (ja) * 2004-08-27 2006-03-02 Niigata University 脳腫瘍の検出方法及びそれに用いる脳腫瘍の検出物質、並びに医薬組成物
WO2007011055A1 (ja) * 2005-07-19 2007-01-25 Otsuka Chemical Co., Ltd. 糖鎖誘導体の製造方法、構造解析方法、及び糖鎖誘導体
JP2007045889A (ja) * 2005-08-08 2007-02-22 Kagawa Univ 糖タンパク質からの糖鎖の調製方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03154866A (ja) * 1989-11-14 1991-07-02 Joko:Kk 腫瘍マーカーの分析方法
WO2006022114A1 (ja) * 2004-08-27 2006-03-02 Niigata University 脳腫瘍の検出方法及びそれに用いる脳腫瘍の検出物質、並びに医薬組成物
WO2007011055A1 (ja) * 2005-07-19 2007-01-25 Otsuka Chemical Co., Ltd. 糖鎖誘導体の製造方法、構造解析方法、及び糖鎖誘導体
JP2007045889A (ja) * 2005-08-08 2007-02-22 Kagawa Univ 糖タンパク質からの糖鎖の調製方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HARADA Y. ET AL.: "Shuyo Marker Nyugan", JAPANESE JOURNAL OF CANCER AND CHEMOTHERAPY, vol. 28, no. 7, 15 July 2001 (2001-07-15), pages 1035 - 1040 *
KOBATA A.: "Keishitsumaku Naizaisei Totanpakushitsu no N-ketsugogata Tosa no Tokucho to sono Gansei Henka", ANNUAL REPORT OF THE NOGUCHI INSTITUTE, no. 49, 2006, pages 4 - 20, XP008153741 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011040008A1 (ja) * 2009-09-30 2011-04-07 国立大学法人北海道大学 糖鎖分析による婦人科がんの診断方法
WO2015186690A1 (ja) * 2014-06-03 2015-12-10 学校法人北里研究所 無水ヒドラジンによる、糖タンパク質からのＯ－結合型糖鎖のβ脱離反応における、脱離した糖鎖の分解抑制剤、キット及び方法
JP2017067677A (ja) * 2015-10-01 2017-04-06 住友ベークライト株式会社 標識糖の精製物を調製する方法

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JPWO2008096790A1 (ja) 2010-05-27

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