WO2011062405A3 - 측방 유동 면역 분석 디바이스 - Google Patents

측방 유동 면역 분석 디바이스 Download PDF

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Publication number
WO2011062405A3
WO2011062405A3 PCT/KR2010/008087 KR2010008087W WO2011062405A3 WO 2011062405 A3 WO2011062405 A3 WO 2011062405A3 KR 2010008087 W KR2010008087 W KR 2010008087W WO 2011062405 A3 WO2011062405 A3 WO 2011062405A3
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pad
flow
whole blood
immunoassay device
sample
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PCT/KR2010/008087
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English (en)
French (fr)
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WO2011062405A2 (ko
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배병우
안범주
신지훈
이석기
장진희
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주식회사 인포피아
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Publication of WO2011062405A2 publication Critical patent/WO2011062405A2/ko
Publication of WO2011062405A3 publication Critical patent/WO2011062405A3/ko

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

본 발명은 전혈 샘플(whole blood sample) 내의 목표 분석물(analyte)을 정량 또는 정성적으로 측정하는 측방 유동 면역 분석 디바이스(lateral flow immunoassay device)를 제공한다. 이 디바이스는 샘플 수용 패드(sample receiving pad), 접합체 패드(conjugate pad), 흐름 지연 패드(flow delaying pad) 및 위킹 멤브레인(wicking membrane)을 측 방향으로 이 순서대로 포함하고 있다. 상기 샘플 수용 패드는 전혈 샘플을 수용하여 이 전혈 샘플로부터 적혈구(red blood cell)를 분리하며, 이로써 상기 적혈구의 흐름을 차단한다. 특히, 상기 샘플 수용 패드, 상기 접합체 패드 및 상기 흐름 지연 패드의 평균 기공 크기를 각기 P1, P2 및 P3라고 할 때에, P1 > P2 > P3의 관계가 성립된다.
PCT/KR2010/008087 2009-11-18 2010-11-16 측방 유동 면역 분석 디바이스 WO2011062405A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020090111353A KR100946566B1 (ko) 2009-11-18 2009-11-18 측방 유동 면역 분석 디바이스
KR10-2009-0111353 2009-11-18

Publications (2)

Publication Number Publication Date
WO2011062405A2 WO2011062405A2 (ko) 2011-05-26
WO2011062405A3 true WO2011062405A3 (ko) 2011-11-03

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Country Link
US (1) US8859265B2 (ko)
KR (1) KR100946566B1 (ko)
WO (1) WO2011062405A2 (ko)

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KR102526986B1 (ko) * 2020-11-25 2023-05-03 (주)오상헬스케어 면역 크로마토그래피를 이용한 신속 진단 키트
KR20220125896A (ko) 2021-03-05 2022-09-15 주식회사 보레다바이오텍 리스테리아 모노사이토제네스 검출용 조성물 및 이를 포함하는 키트
KR102560727B1 (ko) * 2021-07-01 2023-07-26 부경대학교 산학협력단 검출신호 세기를 증가시킨 측방 유동 면역분석 디바이스 및 이를 이용한 표적 물질 검출 방법
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Publication number Publication date
KR100946566B1 (ko) 2010-03-11
WO2011062405A2 (ko) 2011-05-26
US20110117636A1 (en) 2011-05-19
US8859265B2 (en) 2014-10-14

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