WO2008069069A8 - アミド化合物及びその塩、それを用いたバイオフィルム形成阻害剤及びバイオフィルム剥離剤 - Google Patents

アミド化合物及びその塩、それを用いたバイオフィルム形成阻害剤及びバイオフィルム剥離剤

Info

Publication number
WO2008069069A8
WO2008069069A8 PCT/JP2007/072930 JP2007072930W WO2008069069A8 WO 2008069069 A8 WO2008069069 A8 WO 2008069069A8 JP 2007072930 W JP2007072930 W JP 2007072930W WO 2008069069 A8 WO2008069069 A8 WO 2008069069A8
Authority
WO
WIPO (PCT)
Prior art keywords
biofilm
salt
amide compound
same
remover
Prior art date
Application number
PCT/JP2007/072930
Other languages
English (en)
French (fr)
Other versions
WO2008069069A1 (ja
Inventor
Hiroaki Suga
Jun Igarashi
Original Assignee
Univ Tokyo
Otsuka Chemical Co Ltd
Hiroaki Suga
Jun Igarashi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tokyo, Otsuka Chemical Co Ltd, Hiroaki Suga, Jun Igarashi filed Critical Univ Tokyo
Publication of WO2008069069A1 publication Critical patent/WO2008069069A1/ja
Publication of WO2008069069A8 publication Critical patent/WO2008069069A8/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
    • C07D231/52—Oxygen atom in position 3 and nitrogen atom in position 5, or vice versa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

　本発明は、バイオフィルムの形成阻害作用または形成されたバイオフィルムを剥離除去する作用を有する新規アミド化合物及びその塩を提供する。また当該アミド化合物またはその塩を有効成分とするバイオフィルムの形成阻害剤又はバイオフィルム剥離剤を提供する。本発明のアミド化合物またはその塩は下記一般式（１）で表される：  [化１] 〔式中、ＲはＣ１－１１アルキル基を示す。〕。
PCT/JP2007/072930 2006-11-28 2007-11-28 アミド化合物及びその塩、それを用いたバイオフィルム形成阻害剤及びバイオフィルム剥離剤 WO2008069069A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006320753A JP2010043003A (ja) 2006-11-28 2006-11-28 アミド化合物及びその塩、それを用いたバイオフィルム形成阻害剤及びバイオフィルム剥離剤
JP2006-320753 2006-11-28

Publications (2)

Publication Number Publication Date
WO2008069069A1 WO2008069069A1 (ja) 2008-06-12
WO2008069069A8 true WO2008069069A8 (ja) 2008-08-14

Family

ID=39491970

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/072930 WO2008069069A1 (ja) 2006-11-28 2007-11-28 アミド化合物及びその塩、それを用いたバイオフィルム形成阻害剤及びバイオフィルム剥離剤

Country Status (2)

Country Link
JP (1) JP2010043003A (ja)
WO (1) WO2008069069A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6067297B2 (ja) * 2011-10-18 2017-01-25 小林製薬株式会社 義歯洗浄剤
CN104292127B (zh) * 2014-09-02 2016-06-15 中国药科大学 含n-硝基苯基酰胺类化合物抑制生物膜的形成

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2200659C3 (de) * 1972-01-07 1975-02-13 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Wasserunlösliche Disazofarbstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung als Pigmentfarbstoffe
JPS58205151A (ja) * 1982-05-24 1983-11-30 Fuji Photo Film Co Ltd ハロゲン化銀カラ−感光材料
JPS61188541A (ja) * 1985-02-16 1986-08-22 Konishiroku Photo Ind Co Ltd 写真感光材料
JPH02225469A (ja) * 1989-02-28 1990-09-07 Ishihara Sangyo Kaisha Ltd ピラゾロン系化合物又はその塩を含有する抗菌剤
FR2768733B1 (fr) * 1997-09-19 1999-10-29 Oreal Nouveaux composes 4,4-dihydroxypyrazolin-5-ones ; leurs procedes de preparation et utilisations cosmetiques
US6410533B1 (en) * 2000-02-10 2002-06-25 Genzyme Corporation Antibacterial compounds

Also Published As

Publication number Publication date
JP2010043003A (ja) 2010-02-25
WO2008069069A1 (ja) 2008-06-12

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