WO2008012440A3 - Composes pyridaziniques et pyrroliques, procedes d'obtention et applications - Google Patents
Composes pyridaziniques et pyrroliques, procedes d'obtention et applications Download PDFInfo
- Publication number
- WO2008012440A3 WO2008012440A3 PCT/FR2007/001287 FR2007001287W WO2008012440A3 WO 2008012440 A3 WO2008012440 A3 WO 2008012440A3 FR 2007001287 W FR2007001287 W FR 2007001287W WO 2008012440 A3 WO2008012440 A3 WO 2008012440A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- obtaining
- processes
- pyridazine
- pyrrole compounds
- relates
- Prior art date
Links
- PBMFSQRYOILNGV-UHFFFAOYSA-N pyridazine Chemical compound C1=CC=NN=C1 PBMFSQRYOILNGV-UHFFFAOYSA-N 0.000 title 1
- 150000003233 pyrroles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- QFKXFTLPCRTWIO-UHFFFAOYSA-N 3-(1h-pyrrol-2-yl)pyridazine Chemical compound C1=CNC(C=2N=NC=CC=2)=C1 QFKXFTLPCRTWIO-UHFFFAOYSA-N 0.000 abstract 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000030852 Parasitic disease Diseases 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000007613 environmental effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B57/00—Other synthetic dyes of known constitution
- C09B57/10—Metal complexes of organic compounds not being dyes in uncomplexed form
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La présente invention est relative à des composés oligopyridaziniques non linéaires, à leurs procédés d'obtention, à leurs applications, ainsi qu'à leur régression en oligopyrroles et aux applications des composés pyridazinyl-pyrroliques et oligopyrroliques obtenus. L'invention vise en particulier les applications en tant que médicaments, notamment pour traiter des pathologies telles que le cancer, les infections bactériennes ou parasitaires, ainsi que les applications dans le domaine des matériaux, de l'environnement de l'électronique et de l'optique.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009521300A JP5564252B2 (ja) | 2006-07-26 | 2007-07-26 | ピリダジンおよびピロール化合物、それらを得るための方法および使用 |
CA002658624A CA2658624A1 (fr) | 2006-07-26 | 2007-07-26 | Composes pyridaziniques et pyrroliques, procedes d'obtention et applications |
EP07823344A EP2069345A2 (fr) | 2006-07-26 | 2007-07-26 | Composes pyridaziniques et pyrroliques, procedes d'obtention et applications |
US12/309,585 US9034873B2 (en) | 2006-07-26 | 2007-07-26 | Pyridazine and pyrrole compounds, processes for obtaining them and uses |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0606842 | 2006-07-26 | ||
FR0606842A FR2904315B1 (fr) | 2006-07-26 | 2006-07-26 | Composes pyridaziniques et pyrroliques, procedes d'obtention et applications |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008012440A2 WO2008012440A2 (fr) | 2008-01-31 |
WO2008012440A3 true WO2008012440A3 (fr) | 2008-05-29 |
Family
ID=37763892
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR2007/001287 WO2008012440A2 (fr) | 2006-07-26 | 2007-07-26 | Composes pyridaziniques et pyrroliques, procedes d'obtention et applications |
Country Status (6)
Country | Link |
---|---|
US (1) | US9034873B2 (fr) |
EP (1) | EP2069345A2 (fr) |
JP (1) | JP5564252B2 (fr) |
CA (1) | CA2658624A1 (fr) |
FR (1) | FR2904315B1 (fr) |
WO (1) | WO2008012440A2 (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2186810A1 (fr) * | 2008-10-31 | 2010-05-19 | Institut Curie | Dérivés de poly-hétéroaryle pour le traitement de cancer |
US8906850B2 (en) | 2009-01-28 | 2014-12-09 | Smartcells, Inc. | Crystalline insulin-conjugates |
EP2391217A4 (fr) | 2009-01-28 | 2015-05-20 | Smartcells Inc | Conjugués synthétiques et leurs utilisations |
ES2791683T3 (es) | 2009-01-28 | 2020-11-05 | Smartcells Inc | Sistemas a base de conjugados para la administración controlada de fármacos |
US8846103B2 (en) | 2009-01-28 | 2014-09-30 | Smartcells, Inc. | Exogenously triggered controlled release materials and uses thereof |
WO2010107519A1 (fr) | 2009-03-20 | 2010-09-23 | Smartcells, Inc. | Conjugués fonctionnalisés aux extrémités et leurs utilisations |
US8569231B2 (en) | 2009-03-20 | 2013-10-29 | Smartcells, Inc. | Soluble non-depot insulin conjugates and uses thereof |
JP6125742B2 (ja) * | 2009-10-30 | 2017-05-10 | 住友化学株式会社 | 含窒素芳香族化合物及び金属錯体 |
AU2011282977A1 (en) | 2010-07-28 | 2013-02-21 | Smartcells, Inc. | Drug-ligand conjugates, synthesis thereof, and intermediates thereto |
EP2598527A4 (fr) | 2010-07-28 | 2014-01-08 | Smartcells Inc | Polypeptides d'insuline exprimés de façon recombinante et utilisations de ceux-ci |
CA2805902A1 (fr) | 2010-07-28 | 2012-02-02 | Smartcells, Inc. | Lectines recombinees, lectines a site de liaison modifie et leurs utilisations |
JP2014156402A (ja) * | 2011-05-27 | 2014-08-28 | Nippon Soda Co Ltd | ビピリジン化合物および殺菌剤 |
WO2013033018A2 (fr) | 2011-08-30 | 2013-03-07 | Drexel University | Complexes de dihydroxybipyridine de ruthénium et d'iridium destinés à l'oxydation de l'eau et à l'hydrogénation |
WO2014158943A1 (fr) * | 2013-03-13 | 2014-10-02 | Avon Products, Inc | Inhibiteurs de tyrosinase |
WO2014164200A1 (fr) | 2013-03-13 | 2014-10-09 | Avon Products, Inc | Inhibiteurs de la tyrosinase |
WO2014164195A1 (fr) | 2013-03-13 | 2014-10-09 | Avon Products, Inc | Inhibiteurs de tyrosinase |
AU2014329567B2 (en) | 2013-10-04 | 2019-07-25 | Merck Sharp & Dohme Corp. | Glucose-responsive insulin conjugates |
US10130625B2 (en) | 2014-07-22 | 2018-11-20 | University Of Maryland, College Park | Linked diaryl compounds with anticancer properties and methods of using the same |
JP7063231B2 (ja) * | 2018-10-26 | 2022-05-09 | 住友化学株式会社 | ジピリダジニルエーテル化合物及びその用途 |
CN110437206B (zh) * | 2019-03-13 | 2022-06-10 | 上海大学 | 吡啶-吡咯交替的分子折叠体及其制备方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040186288A1 (en) * | 2001-05-08 | 2004-09-23 | Martin Kruger | 3,5-Diamino-1,2,4-triazoles as kinase inhibitors |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3889065B2 (ja) * | 1994-03-15 | 2007-03-07 | 株式会社東芝 | 有機非線形光学材料 |
-
2006
- 2006-07-26 FR FR0606842A patent/FR2904315B1/fr not_active Expired - Fee Related
-
2007
- 2007-07-26 EP EP07823344A patent/EP2069345A2/fr not_active Withdrawn
- 2007-07-26 WO PCT/FR2007/001287 patent/WO2008012440A2/fr active Application Filing
- 2007-07-26 JP JP2009521300A patent/JP5564252B2/ja not_active Expired - Fee Related
- 2007-07-26 CA CA002658624A patent/CA2658624A1/fr not_active Abandoned
- 2007-07-26 US US12/309,585 patent/US9034873B2/en not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040186288A1 (en) * | 2001-05-08 | 2004-09-23 | Martin Kruger | 3,5-Diamino-1,2,4-triazoles as kinase inhibitors |
Non-Patent Citations (3)
Title |
---|
BAXTER P N ET AL: "Self-assembly and structure of interconverting multinuclear inorganic arrays: a [4X5]-Ag(I)20 grid and an Ag(I)10 quadruple helicate", CHEMISTRY - A EUROPEAN JOURNAL, vol. 6, no. 24, 15 December 2000 (2000-12-15), pages 4510 - 4517, XP002422690 * |
COATES W J ET AL: "1,4-Bis(3-oxo-2,3-dihydropyridazin-6-yl) benzene analogs: potent phosphodiesterase inhibitors and inodilators", JOURNAL OF MEDICINAL CHEMISTRY, vol. 33, no. 6, 1990, pages 1735 - 1741, XP002119282 * |
JONES R A ET AL: "Extended heterocyclic systems 1. The synthesis and characterisation of pyrrolylpyridines, alternating pyrrole:pyridine oligomers and polymers, and related systems", TETRAHEDRON, vol. 52, no. 26, June 1996 (1996-06-01), pages 8707 - 8724, XP004103814 * |
Also Published As
Publication number | Publication date |
---|---|
CA2658624A1 (fr) | 2008-01-31 |
WO2008012440A2 (fr) | 2008-01-31 |
US9034873B2 (en) | 2015-05-19 |
FR2904315B1 (fr) | 2012-12-14 |
JP5564252B2 (ja) | 2014-07-30 |
JP2009544671A (ja) | 2009-12-17 |
FR2904315A1 (fr) | 2008-02-01 |
US20100298562A1 (en) | 2010-11-25 |
EP2069345A2 (fr) | 2009-06-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2008012440A3 (fr) | Composes pyridaziniques et pyrroliques, procedes d'obtention et applications | |
WO2007044084A3 (fr) | Inhibiteurs heterocycliques de mek et leurs procedes d'utilisation | |
WO2009140309A3 (fr) | Petites molécules contenant du bore | |
WO2006124713A3 (fr) | 4-biarylyl-1-phenylazetidin-2-ones | |
WO2007150001A8 (fr) | Composés de la pyrro[1,2-b]pyridazinone | |
WO2008115281A3 (fr) | Composés de traitement d'infections virales | |
WO2007064872A3 (fr) | Composes de l'uree utilises dans le traitement du cancer | |
WO2007115821A3 (fr) | Composés organiques | |
WO2009015390A3 (fr) | Co-incubation de communautés microbiennes confinées | |
TN2011000245A1 (en) | Organic compounds | |
WO2008134761A3 (fr) | Modification des groupes de ciblage biologiques pour le traitement du cancer | |
MX2009006536A (es) | Compuestos de heteroaril-heteroarilo como inhibidores de cdk para el tratamiento de cancer, inflamacion e infecciones virales. | |
WO2012061290A3 (fr) | Compositions pesticides et procédés associés | |
WO2012020214A3 (fr) | Cadre de métal organique antibactérien | |
WO2008124660A3 (fr) | Procédés et compositions pour le traitement du cancer | |
WO2006072615A3 (fr) | Triazolophtalazines | |
WO2008127364A3 (fr) | Composés antiviraux et utilisation de ceux-ci | |
WO2006072612A3 (fr) | Triazolophthalazines | |
WO2007133865A3 (fr) | Composés organiques et leurs utilisations | |
WO2009077471A3 (fr) | Azolylméthyloxiranes, leur utilisation et agents les contenant | |
WO2007070613A3 (fr) | Analogues de la rifamycine et leurs utilisations | |
WO2008144223A3 (fr) | Composés triazolyl aminopyrimidine | |
TW200630367A (en) | Substituted adenines and the uses thereof | |
WO2006120563A3 (fr) | Agents antibacteriens | |
WO2008133734A3 (fr) | Procédé et compositions utilisés pour traiter les infections à vih |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 2658624 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 12309585 Country of ref document: US |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2009521300 Country of ref document: JP |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2007823344 Country of ref document: EP |
|
NENP | Non-entry into the national phase |
Ref country code: RU |