WO2008009361A3 - Formulierungen von multikompartimenten-granulaten für wirkstoffe - Google Patents

Formulierungen von multikompartimenten-granulaten für wirkstoffe Download PDF

Info

Publication number
WO2008009361A3
WO2008009361A3 PCT/EP2007/006046 EP2007006046W WO2008009361A3 WO 2008009361 A3 WO2008009361 A3 WO 2008009361A3 EP 2007006046 W EP2007006046 W EP 2007006046W WO 2008009361 A3 WO2008009361 A3 WO 2008009361A3
Authority
WO
WIPO (PCT)
Prior art keywords
active substances
multicompartment
matrix
granulate formulations
percent
Prior art date
Application number
PCT/EP2007/006046
Other languages
English (en)
French (fr)
Other versions
WO2008009361A2 (de
Inventor
Claudia Letmathe
Axel Eble
Olaf Bork
Original Assignee
Bayer Technology Services Gmbh
Claudia Letmathe
Axel Eble
Olaf Bork
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Technology Services Gmbh, Claudia Letmathe, Axel Eble, Olaf Bork filed Critical Bayer Technology Services Gmbh
Priority to EP07785939A priority Critical patent/EP2046117A2/de
Priority to US12/374,568 priority patent/US20090317468A1/en
Publication of WO2008009361A2 publication Critical patent/WO2008009361A2/de
Publication of WO2008009361A3 publication Critical patent/WO2008009361A3/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/12—Powders or granules
    • C—CHEMISTRY; METALLURGY
    • C05—FERTILISERS; MANUFACTURE THEREOF
    • C05G—MIXTURES OF FERTILISERS COVERED INDIVIDUALLY BY DIFFERENT SUBCLASSES OF CLASS C05; MIXTURES OF ONE OR MORE FERTILISERS WITH MATERIALS NOT HAVING A SPECIFIC FERTILISING ACTIVITY, e.g. PESTICIDES, SOIL-CONDITIONERS, WETTING AGENTS; FERTILISERS CHARACTERISED BY THEIR FORM
    • C05G5/00—Fertilisers characterised by their form
    • C05G5/40—Fertilisers incorporated into a matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Abstract

Die vorliegende Erfindung betrifft einen Wirkstoffe enthaltenden Formkörper, umfassend mindestens zwei Kompartimente mit unterschiedlicher stofflicher Zusammensetzung, wobei jedes Kompartiment unabhängig voneinander mindestens einen Wirkstoff aufweist und wobei in den einzelnen Kompartimenten der Wirkstoff jeweils in einer Matrix enthalten ist und die jeweilige Matrix mindestens einen Füllstoff umfasst, worin der Füllstoffgehalt der jeweiligen Matrix, bezogen auf das Gesamtgewicht der jeweiligen Matrix, ≥ 20 Gew.-% bis ≤ 100 Gew.-% ausmacht. Weiterhin betrifft die vorliegende Erfindung ein Verfahren zur Herstellung solcher Formkörper sowie dessen Verwendung.
PCT/EP2007/006046 2006-07-21 2007-07-07 Formulierungen von multikompartimenten-granulaten für wirkstoffe WO2008009361A2 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07785939A EP2046117A2 (de) 2006-07-21 2007-07-07 Formulierungen von multikompartimenten-granulaten für wirkstoffe
US12/374,568 US20090317468A1 (en) 2006-07-21 2007-07-07 Multicompartment granulate formulations for active substances

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006033723.9 2006-07-21
DE102006033723A DE102006033723A1 (de) 2006-07-21 2006-07-21 Formulierungen von Multikompartimenten-Granulaten für Wirkstoffe

Publications (2)

Publication Number Publication Date
WO2008009361A2 WO2008009361A2 (de) 2008-01-24
WO2008009361A3 true WO2008009361A3 (de) 2008-03-27

Family

ID=38830714

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/006046 WO2008009361A2 (de) 2006-07-21 2007-07-07 Formulierungen von multikompartimenten-granulaten für wirkstoffe

Country Status (5)

Country Link
US (1) US20090317468A1 (de)
EP (1) EP2046117A2 (de)
CN (1) CN101489378A (de)
DE (1) DE102006033723A1 (de)
WO (1) WO2008009361A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015059580A1 (en) 2013-10-21 2015-04-30 Hicap Formulations Ltd. Controlled release formulations of herbicides
ITBO20130607A1 (it) * 2013-11-05 2015-05-06 Chemia S P A Formulato biostimolante, corroborante e concimante a base di zeolite ed estratti naturali vegetali
CN103688945A (zh) * 2013-12-10 2014-04-02 济南凯因生物科技有限公司 防治小麦白粉病的组合物
JP6735235B2 (ja) 2014-05-05 2020-08-05 サビック グローバル テクノロジーズ ベスローテン フエンノートシャップ 被覆粒状肥料、その製造方法、及び使用
US11124463B2 (en) 2015-11-16 2021-09-21 Sabic Global Technologies B.V. Coated granular fertilizers, methods of manufacture thereof, and uses thereof
US11806689B2 (en) 2016-02-08 2023-11-07 Sabic Global Technologies B.V. Method of making a fertilizer seed core
CN110770194A (zh) 2017-04-19 2020-02-07 沙特基础工业全球技术公司 具有在单独颗粒中的尿素酶抑制剂和硝化抑制剂的增效肥料
WO2018193344A1 (en) 2017-04-19 2018-10-25 Sabic Global Technologies B.V. Enhanced efficiency fertilizer with urease inhibitor and nitrification inhibitor separated within the same particle
WO2018193345A1 (en) 2017-04-20 2018-10-25 Sabic Global Technologies B.V. Enhanced efficiency fertilizer with embedded powder composition
CN111183126A (zh) * 2017-08-09 2020-05-19 沙特基础工业全球技术公司 含有脲酶抑制剂和/或硝化抑制剂的挤出肥料颗粒
US11203554B2 (en) * 2018-12-07 2021-12-21 Imerys Usa, Inc. Anticaking agent for hygroscopic fertilizer

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000044404A (ja) * 1998-07-27 2000-02-15 Otsuka Chem Co Ltd 農業用混合粒剤
WO2001013721A1 (en) * 1999-08-26 2001-03-01 Agform Ltd. Water-dispersible agrochemical compositions
WO2001084928A1 (de) * 2000-05-11 2001-11-15 Bayer Cropscience Gmbh Kombinationen von pflanzenschutzmitteln mit organischen oder anorganischen trägermaterialien
EP1213014A2 (de) * 2000-12-07 2002-06-12 Warner-Lambert Company Verfahren und System zur gesteuerten Arzneistoffabgabe
JP2002179505A (ja) * 2000-12-12 2002-06-26 Mitsui Chemicals Inc 被覆型徐放性農薬粒剤
WO2003011283A1 (en) * 2001-07-31 2003-02-13 Warner-Lambert Company Llc Pharmaceutical compositions of amlodipine and atorvastatin
JP2003095832A (ja) * 2001-09-20 2003-04-03 Bayer Cropscience Kk 水田用雑草病害虫防除剤
WO2003028453A1 (de) * 2001-09-28 2003-04-10 Basf Aktiengesellschaft Biologisch abbaubare feste zubereitung eines pflanzenschutzmittels mit verzögerter wirkstoffreisetzung
EP1552743A1 (de) * 2002-08-07 2005-07-13 Nippon Soda Co., Ltd. Agrachemische zusammensetzung in granulatform
WO2006084474A2 (en) * 2005-02-10 2006-08-17 Lifecycle Pharma A/S A stable pharmaceutical composition comprising a fixed dose combination of fenofibrate and an hmg-coa reductase inhibitor
WO2007042185A2 (en) * 2005-10-11 2007-04-19 Syngenta Participations Ag Granular compositions and methods for combatting rice pests and fungal diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA74141C2 (uk) * 1998-12-09 2005-11-15 Дж.Д. Сірл Енд Ко. Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти)
US7670612B2 (en) * 2002-04-10 2010-03-02 Innercap Technologies, Inc. Multi-phase, multi-compartment capsular delivery apparatus and methods for using same
JP2007509155A (ja) * 2003-10-21 2007-04-12 アルファーマ インコーポレイテッド クエチアピンを含有する薬剤
WO2006123357A2 (en) * 2005-02-22 2006-11-23 Sun Pharmaceutical Industries Limited Oral controlled release composition containing levetiracetam

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000044404A (ja) * 1998-07-27 2000-02-15 Otsuka Chem Co Ltd 農業用混合粒剤
WO2001013721A1 (en) * 1999-08-26 2001-03-01 Agform Ltd. Water-dispersible agrochemical compositions
WO2001084928A1 (de) * 2000-05-11 2001-11-15 Bayer Cropscience Gmbh Kombinationen von pflanzenschutzmitteln mit organischen oder anorganischen trägermaterialien
EP1213014A2 (de) * 2000-12-07 2002-06-12 Warner-Lambert Company Verfahren und System zur gesteuerten Arzneistoffabgabe
JP2002179505A (ja) * 2000-12-12 2002-06-26 Mitsui Chemicals Inc 被覆型徐放性農薬粒剤
WO2003011283A1 (en) * 2001-07-31 2003-02-13 Warner-Lambert Company Llc Pharmaceutical compositions of amlodipine and atorvastatin
JP2003095832A (ja) * 2001-09-20 2003-04-03 Bayer Cropscience Kk 水田用雑草病害虫防除剤
WO2003028453A1 (de) * 2001-09-28 2003-04-10 Basf Aktiengesellschaft Biologisch abbaubare feste zubereitung eines pflanzenschutzmittels mit verzögerter wirkstoffreisetzung
EP1552743A1 (de) * 2002-08-07 2005-07-13 Nippon Soda Co., Ltd. Agrachemische zusammensetzung in granulatform
WO2006084474A2 (en) * 2005-02-10 2006-08-17 Lifecycle Pharma A/S A stable pharmaceutical composition comprising a fixed dose combination of fenofibrate and an hmg-coa reductase inhibitor
WO2007042185A2 (en) * 2005-10-11 2007-04-19 Syngenta Participations Ag Granular compositions and methods for combatting rice pests and fungal diseases

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 16 February 2000 (2000-02-16), M. ARAI, K. ODAWARA, K. OCHIAI & K. UOMOTO: "Composite agrochemical pestcide granules containing two active ingredients", XP002464930, retrieved from STN accession no. 2000:111149 Database accession no. 132:148021 *
DATABASE WPI Week 200310, Derwent World Patents Index; AN 2003-106065, XP002464931 *
DATABASE WPI Week 200356, Derwent World Patents Index; AN 2003-590936, XP002465079 *

Also Published As

Publication number Publication date
WO2008009361A2 (de) 2008-01-24
DE102006033723A1 (de) 2008-01-24
EP2046117A2 (de) 2009-04-15
CN101489378A (zh) 2009-07-22
US20090317468A1 (en) 2009-12-24

Similar Documents

Publication Publication Date Title
WO2008009361A3 (de) Formulierungen von multikompartimenten-granulaten für wirkstoffe
BR0215768A (pt) Processo para a preparação de uma composição polimérica de polipropileno com borracha biomodal, produto polimérico, uso do polìmero, e, artigo moldado
AR062862A1 (es) Una composicion, un articulo abrasivo y un metodo de procesado abrasivo
BR112013015078A2 (pt) composto, composição fotocromática e artigo fotocromático
WO2006101751A3 (en) A composite spinal nucleus implant with water absorption and swelling capabilities
TW200636007A (en) Thermoplastic polycarbonate compositions, articles made therefrom and method of manufacture
WO2009047466A3 (fr) Procédé de préparation de matériaux composites
MY164777A (en) Filled polyamide molding materials
RS20060126A (en) Transparent moulding composition
WO2010103187A3 (en) Novel composite materials comprising a thermoplastic matrix polymer amd wood particules
WO2006102101A3 (en) Cellulosic inorganic-filled plastic composite
WO2006127069A3 (en) A delivery system for active components as part of an edible composition including a ratio of encapsulating material and active component
WO2008118214A3 (en) Transparent composite articles
PL1940230T3 (pl) Grzybobójcze zwalczanie pleśni
GB0515492D0 (en) Improvements in or relating to compositions,articles and methods
WO2010074721A3 (en) Anitmicrobial agents, compositions and products containing the same, and methods of using the compositions and products
SM200700008A (it) Impianto perfezionato per la produzione per iniezione di prodotti in materiale plastico espanso, quale eva, in particolare suole oppure prodotti in generale con caratteristiche di leggerezza e comfort
IL192328A (en) Walls of yeast cells for the treatment and protection of plants against diseases caused by pathogenic factors and compounds containing these walls of yeast cells
WO2009044042A3 (fr) Composition d'ensimage sous forme de gel physique pour fils de verre, fils de verre obtenus et composites comprenant lesdits fils
WO2007006521A3 (en) Nutritional mixtures with a high and increased efficacy
BRPI0807271A2 (pt) 'uso de uma composição, formulações no estado fundido e processo de fabricação de um artigo de poliamida microcelular"
WO2009151339A3 (en) Packaging for biological material
CL2008001648A1 (es) Compuestos derivados de triazol[1,5-a]quinolina; proceso de preparacion; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como asma, epoc, artritis reumatoide, isquemia, entre otras.
WO2007060208A8 (en) Fast-dissolving isotropic expanded microporous composition or structure for pharmaceutical, veterinary, dietetic, food or cosmetic use and method for obtaining same
WO2005097320A3 (en) Compositions and methods for imparting odor resistance and articles thereof

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200780027638.2

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07785939

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2007785939

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: DE

NENP Non-entry into the national phase

Ref country code: RU

WWE Wipo information: entry into national phase

Ref document number: 12374568

Country of ref document: US