WO2008004670A1 - Système de remplissage et d'injection de liquide chimique, et dispositif de remplissage associé - Google Patents

Système de remplissage et d'injection de liquide chimique, et dispositif de remplissage associé Download PDF

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Publication number
WO2008004670A1
WO2008004670A1 PCT/JP2007/063588 JP2007063588W WO2008004670A1 WO 2008004670 A1 WO2008004670 A1 WO 2008004670A1 JP 2007063588 W JP2007063588 W JP 2007063588W WO 2008004670 A1 WO2008004670 A1 WO 2008004670A1
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WO
WIPO (PCT)
Prior art keywords
chemical
filling
syringe
chemical solution
data
Prior art date
Application number
PCT/JP2007/063588
Other languages
English (en)
Japanese (ja)
Inventor
Shigeru Nemoto
Original Assignee
Nemoto Kyorindo Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nemoto Kyorindo Co., Ltd. filed Critical Nemoto Kyorindo Co., Ltd.
Priority to JP2008523761A priority Critical patent/JP5149798B2/ja
Publication of WO2008004670A1 publication Critical patent/WO2008004670A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14546—Front-loading type injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/60—General characteristics of the apparatus with identification means
    • A61M2205/6018—General characteristics of the apparatus with identification means providing set-up signals for the apparatus configuration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/60—General characteristics of the apparatus with identification means
    • A61M2205/6054—Magnetic identification systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/04—Tools for specific apparatus
    • A61M2209/045—Tools for specific apparatus for filling, e.g. for filling reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1456—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir

Definitions

  • the present invention relates to a chemical solution filling / injecting system including a chemical solution filling device that fills a chemical solution into a chemical solution syringe and a chemical solution injection device that injects a chemical solution into a subject such as a chemical syringe filled with the chemical solution.
  • Medical diagnostic imaging devices include CT (Computed Tomography) scanner, MRI (Magnetic Resonance Imaging), PET (Positron
  • Emission Tomography equipment
  • Angio equipment equipment
  • MRA MR Angio
  • a chemical solution injection apparatus has an injection head to which a chemical solution syringe is detachably attached.
  • the drug solution syringe is filled with the drug solution, and the drug solution in the drug solution syringe can be injected into the subject by pushing the piston of the drug solution syringe into the cylinder by the drive mechanism provided in the injection head.
  • Medical solution syringes are classified into a prefilled type in which a chemical solution is pre-filled and a post-filling type in which a desired chemical solution is filled when being injected into a subject.
  • the liquid medicine is filled into the liquid syringe exclusively by medical personnel at the medical site.
  • manually filling the chemical syringe with the chemical solution has a large work load, and therefore the chemical syringe is filled with the chemical solution using a chemical solution filling apparatus.
  • Patent Document 1 As a conventional chemical solution filling apparatus, the one described in Patent Document 1 is known.
  • the chemical liquid filling device described in Patent Literature 1 calculates the amount of chemical liquid required based on the input inspection conditions when the inspection conditions are input, and the piston member according to the calculated amount of chemical liquid. Move. Thereby, the chemical
  • Patent Document 2 chemical liquid data and syringe data are acquired by a chemical liquid filling device.
  • the chemical filling device fills the chemical solution from the chemical solution container into the chemical solution syringe and transmits the chemical solution data and the syringe data to the chemical solution injection device.
  • the chemical data includes data such as the type of chemical, whether it is for MR or CT, when it was used, and expiration date.
  • Syringe data includes data such as the types of chemicals that can be used, whether it is for MR or CT, the intended use, capacity, material, and expiration date.
  • the chemical filling device can determine the suitability of the combination of the chemical and syringe from the chemical data and the syringe data. Is possible.
  • the chemical solution injection device determines that the combination of the chemical solution and the syringe is appropriate based on the received data of the chemical solution filling device force, the chemical solution injection device injects the chemical solution such as a chemical syringe. As a result, it is possible to prevent an inappropriate chemical from being injected into the subject.
  • Patent Document 1 JP 2000-189515 A
  • Patent Document 2 Japanese Patent Application Laid-Open No. 2004-313579
  • the chemical solution filling device described in Patent Document 1 is independent of the chemical solution injection device, and transmission / reception of data between the two is not considered.
  • the chemical injection device sets injection conditions such as the injection amount of the chemical solution to the subject.
  • the injection amount is obtained based on the inspection conditions and corresponds to the filling amount of the chemical liquid filled in the chemical syringe with the chemical liquid filling device.
  • the chemical injection device neither outputs the inspection conditions input to the chemical solution filling device nor the filling amount calculated by the chemical solution filling device to the outside as data. Therefore, the operator needs to input the same data to the chemical injection device as that input to the chemical filling device.
  • the chemical solution injection device described in Patent Document 2 injects a chemical solution from another chemical solution syringe based on the data transmitted from the chemical solution filling apparatus. As a result, the drug solution is injected into the subject under incorrect injection conditions.
  • the present invention attaches the data used for filling the chemical solution with the chemical solution filling device to the chemical solution injection device when the chemical solution syringe filled with the chemical solution with the chemical solution filling device is attached to the chemical solution injection device. It aims at making it correspond to the chemical
  • a chemical solution filling and injecting system of the present invention is a chemical solution filling and injecting system in which an empty chemical solution syringe is filled with a chemical solution, and the chemical solution is injected into a subject from the chemical solution syringe filled with the chemical solution.
  • the chemical solution filling device calculates the filling amount of the chemical solution into the empty chemical solution syringe, and fills the chemical solution syringe by operating the chemical solution syringe based on the obtained filling amount.
  • a chemical solution injector is equipped with a chemical syringe filled with a chemical solution, and injects a chemical solution such as a chemical syringe by operating the attached chemical syringe.
  • the chemical solution filling device and the chemical solution injection device can transmit / receive data to / from each other, and transmit / receive data including the filling amount obtained by the chemical solution filling device and the unique identification number of the chemical solution syringe to each other. Determine injection conditions.
  • the chemical liquid filling and injecting system of the present invention data including the filling amount obtained by the chemical liquid filling apparatus and the unique identification number of the chemical liquid syringe is transmitted and received between the chemical liquid filling apparatus and the chemical liquid injecting apparatus. Therefore, the injection conditions are determined in accordance with the unique identification number of the chemical syringe attached to the chemical injection device.
  • the chemical liquid filling apparatus has at least an interface unit for transmitting data to the chemical liquid injecting apparatus, and there are few chemical liquid injecting apparatuses. Both have an interface unit for receiving chemical solution filling device force data, and the filling amount data can be configured to be transmitted from the chemical solution filling device to the chemical solution injection device via these interface units. Monkey.
  • the chemical solution filling apparatus is also provided with a filling operation mechanism for operating the chemical solution syringe to fill the chemical solution syringe, an input unit for inputting data related to the inspection condition by the chemical solution, and an input unit force. It is preferable to include a calculation unit that calculates the filling amount based on the data, and at least sends a calculation result to the interface unit, and a filling control unit that controls the filling operation mechanism according to the calculation result in the calculation unit.
  • the interface unit can be a reader Z writer that reads and writes data to and from an IC tag provided on a chemical syringe.
  • the chemical solution filling device and the chemical solution injection device may be connected wirelessly or by wire via the interface unit.
  • At least one of the chemical solution injecting device and the chemical solution filling device may be connected to a management server that manages medical chart information.
  • the chemical liquid filling apparatus of the present invention is a chemical liquid filling apparatus that fills the chemical liquid syringe with a chemical liquid by operating an empty chemical liquid syringe, and is obtained by obtaining a filling amount of the chemical liquid into the chemical liquid syringe. Based on the filled amount, it has a filling control unit that controls the operation of the chemical syringe, so that the obtained filling amount data is transmitted to other external devices together with the unique identification number of the chemical syringe. It is connected to an external device so that it can send and receive data.
  • the chemical liquid filling apparatus of the present invention includes a filling operation mechanism for operating a chemical liquid syringe to fill the chemical liquid syringe with a chemical liquid syringe, and an input unit for inputting data related to the inspection conditions by the chemical liquid. Furthermore, the filling control unit calculates the filling amount of the liquid medicine into the liquid medicine syringe based on the data input to the input section force, and at least the calculation result via the interface section is unique to the liquid medicine syringe. It can be configured to have a calculation unit that transmits to the other external device together with the identification number, and a filling control unit that controls the filling operation mechanism according to the calculation result of the calculation unit.
  • the interface unit is a reader Z writer that reads and writes data to and from an IC tag provided on the chemical syringe, and a cable for wired connection with an external device.
  • a reader Z writer that reads and writes data to and from an IC tag provided on the chemical syringe, and a cable for wired connection with an external device.
  • Single data connector or a wireless data communication device for wireless connection with an external device.
  • the operator since the data when the chemical solution is filled in the chemical solution filling device can be used to determine the injection condition of the chemical solution, the operator inputs data redundantly to the chemical solution filling device and the chemical solution injection device. It is possible to greatly reduce the work burden on the operator.
  • the data sent to the chemical injection device is associated with the chemical syringe that is attached to the chemical injection device, it is based on the data of other chemical syringes not attached to the chemical injection device. Therefore, it is possible to prevent the injection of chemicals under wrong injection conditions.
  • FIG. 1 is a diagram showing an overall configuration of a fluoroscopic imaging system according to a first embodiment of the present invention.
  • FIG. 2 is a block diagram of the chemical liquid filling device shown in FIG.
  • FIG. 3 is a perspective view showing an appearance of the chemical liquid injector shown in FIG. 1.
  • FIG. 4 is a perspective view showing the appearance of the injection head shown in FIG.
  • FIG. 5 is a block diagram of an example of the chemical liquid injector shown in FIG. 1.
  • FIG. 6 is a block diagram of a modified example of the chemical liquid filling device shown in FIG.
  • FIG. 7 is a diagram showing an overall configuration of a fluoroscopic image capturing system according to a second embodiment of the present invention.
  • FIG. 8 is a block diagram of the chemical liquid filling device shown in FIG.
  • FIG. 9 is a block diagram of the chemical liquid injector shown in FIG. 7.
  • FIG. 10 is a block diagram of a modified example of the chemical liquid filling device shown in FIG.
  • a fluoroscopic image imaging system 10000 which includes a chemical liquid injection device 100, a chemical liquid filling device 200, and a CT device 300 that is an imaging device. Has been.
  • the chemical liquid filling device 200 fills the chemical liquid syringe 500 with the chemical liquid stored in the chemical liquid container 600.
  • the chemical solution injection device 100 injects the chemical solution filled in the chemical solution syringe 500 from the chemical solution syringe 500 to the subject.
  • the chemical solution filling device 200 and the chemical solution injection device 100 constitute a chemical solution filling and injection system.
  • the CT apparatus 300 captures a fluoroscopic image of a subject into which a chemical solution has been injected, and includes an imaging unit 301 that performs imaging and an imaging control unit 302 that controls the operation of the imaging unit 301. Imaging control unit 302 and chemicals It is connected to the injection mute 100 so that they can communicate with each other!
  • the chemical injection device 100 and the CT device 300 are communicably connected to the hospital management server 400.
  • the hospital management server 400 manages medical chart information and has a database of medical chart information including information on subjects.
  • the chemical syringe 500 includes a cylinder 501 and a piston 502 provided in the cylinder 501 so as to be able to advance and retreat.
  • the cylinder 501 has a conduit portion 501b at one end thereof, and the piston 502 is also inserted into the cylinder 501 with the other end portion being the end opposite to the one end portion of the cylinder 501.
  • a cylinder flange 501 a is formed at the other end of the cylinder 501.
  • the piston 502 has a piston flange 502a at the end opposite to the end inserted into the cylinder 501.
  • the cylinder 501 is provided with an IC tag 503.
  • the IC tag 503 is also called a wireless IC tag, a non-contact IC tag, a non-contact IC chip, a non-contact data carrier, or the like, and is a device that uses RF—ID (Radio Frequency-Identification) technology.
  • the IC tag 503 indicates a medium having an integrated circuit with a memory that performs data communication using a wireless or other non-contact communication medium and records information such as a solid identification code in a recordable or rewritable manner. .
  • the IC tag 503 includes data (syringe data) relating to the chemical syringe 500, such as a unique identification number such as manufacturer, product number, serial number, date of manufacture, expiration date (number of times), capacity, piston stroke, etc. Data is recorded.
  • the IC tag 503 may be attached to the outer peripheral surface of the cylinder 501 with a label, or may be bonded with an adhesive. Alternatively, the IC tag 503 can be embedded in the cylinder 501.
  • FIG. 1 is a block diagram of the chemical liquid filling device 200 shown in FIG. 1 and FIG.
  • the chemical solution syringe 500 is detachably attached, and the chemical solution syringe 500 attached is filled with the chemical solution.
  • the amount of the chemical solution that the chemical solution filling device 200 fills the chemical solution syringe 500 is equal to the amount of the chemical solution that is injected into the subject by the chemical solution injection device 100 (see FIG. 1). Therefore, filling the chemical syringe 500 with chemical solution The filling amount varies depending on the examination condition of the subject by the fluoroscopic imaging system 1000.
  • the chemical liquid filling apparatus 200 includes a filling control unit 210 that controls the entire operation of the chemical liquid filling apparatus 200, and a filling control unit 210.
  • the reader Z writer 230 reads data written in the IC tag 503 and writes data into the IC tag 503 in a non-contact manner. Therefore, the reader Z writer 230 is arranged at a position where the IC tag 503 provided on the chemical syringe 500 is within the communicable range when the chemical syringe 500 is attached to the chemical filling device 200.
  • the input unit 240 can be configured by a key switch touch panel or the like, and accepts data input operations by an operator. In the input unit 240, data relating to the inspection conditions used to determine the amount of the chemical solution filled in the chemical syringe 500 is input.
  • the subject data includes, for example, the weight, sex, height, age, and the like of the subject into which the chemical liquid filled in the chemical syringe 500 is injected.
  • the chemical data includes, for example, the type of chemical solution to be filled, manufacturer, product number, viscosity, if the chemical solution is a contrast medium, its concentration of sword, and Sarako uses other types of physiological saline. Or not.
  • the imaging conditions include the subject's imaging site, imaging time, and the like.
  • the liquid medicine filling device 200 may be configured so that syringe data is also input from the input unit 240 by the operator.
  • the data transmitter / receiver may be a writer having a writing function.
  • the filling control unit 210 includes a determination unit 211, a calculation unit 212, a filling control unit 213, and a database 214.
  • the determination unit 211 includes the syringe data read by the reader Z writer 230 and the input unit 240. From the data regarding the inspection conditions entered from the above, it is determined whether or not the chemical liquid filling the chemical syringe 500 is appropriate. The suitability of the chemical liquid filling includes, for example, whether or not the chemical syringe 500 has exceeded the expiration date (number of times), whether the chemical to be filled is a chemical suitable for this test, and the chemical syringe 500 and the chemical Whether or not the combination is appropriate. If it is determined as inappropriate as a result of the determination, the filling control unit 210 issues a warning by a buzzer (not shown), a warning lamp (not shown) or the like, and stops the subsequent operation. On the other hand, if it is determined to be appropriate, the determination unit 211 sends the syringe data read by the reader Z writer 230 and the data input from the input unit 240 to the calculation unit 212 as they are.
  • the calculation unit 212 calculates the filling amount of the drug solution into the drug solution syringe 500 based on the sent data.
  • the filling amount of the chemical solution that is, the injection amount of the chemical solution into the subject, is optimal for capturing a good image.
  • Subject factors such as the subject's weight, height, sex, and age, chemical components, chemical properties, etc. It depends on the imaging factors such as factors, imaging location and imaging time.
  • contrast media when the drug solution is a contrast medium, one of the important factors for obtaining a good image is the total injection amount of sodo. Contrast media have different odoid concentrations depending on the type, and different types of contrast media have different amounts of sodo contained in the same amount.
  • coefficient data for each imaging region active ingredient data for each type of drug (for example, in the case of a contrast agent, iodine-containing concentration data for each type of contrast medium), and physical information such as the body weight and height of the subject.
  • the total injection amount data of the drug corresponding to the above is stored in the database 214.
  • the calculation unit 212 refers to the database 214, and applies the data regarding the above-described inspection conditions to a calculation formula determined in advance in consideration of these various factors. Calculate the amount. Note that the calculation procedure of the filling amount of the chemical solution in the calculation unit 212 may be the same as the calculation procedure of the injection amount of the chemical solution in the conventional chemical injection device, so here the specific calculation formulas and calculation methods are described. Omitted.
  • the calculation unit 212 adds the data input from the input unit 240 and the filling amount calculated by the calculation unit 212 to the IC tag 503 through the reader Z writer 230. If these data are already recorded at the previous filling, rewrite these data. [0045] Based on the filling amount calculated by the calculation unit 212, the filling control unit 213 controls the filling operation mechanism 220 so that the chemical solution syringe 500 is filled with the calculated filling amount.
  • the charging operation mechanism 220 has a cylinder holder 221 and a piston holder 222.
  • the cylinder holder 221 is formed with an arc-shaped concave portion for receiving the cylinder flange 501a of the chemical liquid syringe 500 on its side surface.
  • the recess is formed in a stepped shape having a placement surface on which the cylinder flange 501a is placed.
  • the cylinder 501 is held by the cylinder holder 221 by placing the cylinder flange 501a so that the conduit portion 501b faces upward on the mounting surface.
  • the piston holder 222 is disposed below the cylinder holder 221 so as to face the cylinder holder 221, and in a direction away from the cylinder holder 221 (arrow A direction) and a direction approaching the cylinder holder 221 (arrow B direction). It is provided to be movable. As with the cylinder holder 221, the piston holder 222 is also formed with a recess on the side surface for receiving the piston 502. The piston 502 is held in the recess in a state where the piston flange 502a is positioned below the piston holder 222 (on the side opposite to the side facing the cylinder holder 221).
  • the piston 502 is pulled out from the cylinder 501 by moving the piston holder 222 in the direction of arrow A while holding the cylinder flange 501a and the piston 502. On the other hand, the piston 502 is pushed into the cylinder 501 by moving the piston holder 222 in the arrow B direction.
  • any driving mechanism such as a ball screw mechanism can be used as long as the mechanism can linearly move the piston holder 502.
  • a ball screw mechanism is used as a drive mechanism for the piston holder 502
  • the ball screw shaft is arranged in parallel with the moving direction of the piston holder 502
  • the piston holder 502 is fixed to a ball screw nut that is screwed to the ball screw shaft.
  • the piston holder 502 can be moved in the axial direction of the ball screw shaft as the ball screw shaft rotates.
  • a stepping motor can be used as a drive source for the ball screw shaft.
  • the filling amount of the chemical liquid into the chemical syringe 500 is proportional to the movement amount of the piston 222 relative to the cylinder 221 when the piston 222 is moved in the direction of pulling out the piston 222 from the cylinder 221. did Accordingly, the filling control unit 213 controls the filling operation mechanism so that the piston holder 222 moves by the movement amount corresponding to the filling amount calculated by the calculation unit 212. As a result, the chemical liquid syringe 500 is filled with the amount of chemical liquid calculated by the calculation unit 212.
  • the chemical liquid filling device 200 has a touch panel 241 that also serves as the input unit 240 and the display unit 250 shown in FIG.
  • the chemical solution syringe 500 is held in a vertical state so that the conduit portion 501b faces upward, but the orientation of the held chemical solution syringe 500 is as follows. It may be arbitrary such as a horizontal direction or an oblique direction. Further, regarding the operation of the chemical syringe 500, the force shown in the example in which the cylinder holder 221 is fixed and the piston holder 222 is moved may be fixed and the cylinder holder 221 may be moved by fixing the piston holder 222. Alternatively, both the cylinder holder 221 and the piston holder 222 can be moved.
  • the filling control unit 210 has a determination unit 211.
  • the force determination unit 211 is not essential in the present invention. For example, the operator may determine whether or not the chemical syringe 500 and the chemical solution are appropriate, or the function of the determination unit 211 may be incorporated in the calculation unit 212 to determine whether or not the calculation unit 212 is appropriate. ,.
  • the chemical injection device 100 is connected to an injection head 110 attached to an upper portion of a movable arm 112 connected to a stand 111, and the injection head 110 and a cable 102.
  • an injection control unit 101 includes an operation panel 103 that is an input unit, a display unit 104, and a node unit 107 connected by a cable 108, and controls the operation of the injection head 110.
  • the injection head 110 is formed with two recesses 114 for holding the cylinders 501 in the head body 113 so that two chemical syringes 500 can be attached at a time.
  • the head body 113 is provided with two piston drive mechanisms 130 that are driven independently of each other, corresponding to the respective recesses 114.
  • Piston drive mechanism 130 has its tip It is configured to hold the piston flange of piston 502!
  • one of the drug solutions filled in the drug solution syringe 500 can be a contrast medium and the other can be physiological saline.
  • Two chemical syringes 500 attached to the head body 113 are connected by a connecting tube 530.
  • An extension tube (not shown) having a distal end portion connected to a catheter (not shown) is connected to the connection tube 530.
  • a reader Z writer 140 that reads data written to the IC tag 503 provided in the chemical syringe 500 and writes data to the IC tag 503 in a non-contact manner is provided. It is provided corresponding to the mounting position of the chemical syring 500.
  • the reader Z writer 140 is one of interface units for transmitting / receiving data to / from an external device, specifically, the chemical solution filling device 200.
  • the injection control unit 101 has an injection control unit 121 and an injection profile storage unit 122.
  • an injection control unit 121 When the chemical solution syringe 500 is attached to the injection head 110 and the reader Z writer 140 reads each data from the IC tag 503 (see FIG. 4), each read data is sent to the injection control unit 121.
  • the injection control unit 121 displays each data read by the reader Z writer 140 on the display unit 104 as a numerical value or an image, and reads the injection profile from the injection profile storage unit 122.
  • the data sent from the reader Z writer 140 includes the filling amount data written in the IC tag 503 by the chemical filling device 200 (see FIG. 1). In the chemical injection device 100, the filling amount data is handled as the injection amount data.
  • the infusion profile storage unit 122 stores at least one infusion profile corresponding to the chemical solution.
  • injection profiles include (1) Profile with constant injection rate,
  • the rate of change of the injection rate is determined so that the injection of the chemical solution is completed in a predetermined time.
  • a profile having at least one stage (including only one) having a stage in which the injection rate changes with respect to the elapsed time from the start of the injection is preferable.
  • Injection start force A profile that linearly decreases until a certain time and thereafter maintains or increases the injection rate constant, and decreases the contrast agent injection rate (eg linearly) in at least one stage, while simultaneously Profiles that increase the rate of saline injection.
  • the injection control unit 121 based on the injection amount data of the chemical solution obtained from the chemical syringe 500, and the injection profile read from the injection profile storage unit 122, a predetermined amount of the chemical solution at a predetermined time.
  • the injection condition of the chemical solution is determined so that the subject is injected with a predetermined injection profile.
  • the injection control unit 121 controls the piston drive mechanism 130 so that the piston drive mechanism 130 operates in an operation sequence according to the determined injection condition.
  • the operation panel 123 has an injection start button.
  • the injection control unit 121 actually operates the piston drive mechanism 130.
  • the operation panel 103 further includes a profile selection button, and the operator can select one of the injection profiles. It ’s like that.
  • the operator prepares an empty chemical syringe 500, that is, a chemical syringe 500 that is filled with the chemical solution, and a chemical solution container 600 that contains the chemical solution to be filled in the chemical syringe 500. .
  • the chemical syringe 500 is in a state where the piston 502 is pushed most into the cylinder 501. It is assumed that the chemical solution injection device 100, the chemical solution filling device 200, the CT device 300, and the like constituting the fluoroscopic image system 1000 are already prepared.
  • the operator attaches the prepared empty chemical solution syringe 500 to the chemical solution filling apparatus 200 with the conduit portion 501b facing upward. After the chemical solution syringe 500 is attached, the operator connects the chemical solution container 600 and the chemical solution syringe 500 with the tube 610.
  • the operator inputs data necessary for determining the filling amount of the chemical solution into the chemical solution syringe 500 from the touch panel 241 of the chemical solution filling apparatus 200 as described above.
  • the chemical filling device 200 reads the syringe data recorded on the IC tag 503 of the chemical syringe 500 attached.
  • the chemical solution filling apparatus 200 determines whether or not the chemical solution is charged into the chemical solution syringe 500 based on the data input by the operator and the syringe data read from the IC tag 503. As a result, if determined to be appropriate, the chemical filling device 200 calculates the filling amount of the chemical liquid into the chemical syringe 500 using the input data, and fills the chemical syringe 500 with the chemical liquid according to the calculation result. .
  • the touch panel 241 displays the type of the chemical liquid syringe 500 as an initial screen (for example, capacity and usage). Is displayed.
  • the touch panel 241 also displays a schematic image of the body segment to be injected with the chemical.
  • the schematic image of the body section is an image schematically representing the human body divided into a plurality of sections such as “head”, “chest”, “abdomen”, and “leg”. The operator selects one body segment by touching one of these schematic images.
  • the touch panel 241 When a body segment is selected, the selected body segment is visually distinguished from other body segments, such as by darkening or changing hue.
  • the touch panel 241 further displays an imaging region corresponding to the selected body section. For example, when “chest” is selected as the body classification, the imaging region is “heart” and “lung”.
  • the imaged part may be displayed in text, or may be displayed together with an icon that represents the characteristics of the imaged part. The operator selects one imaging part by touching one of these imaging parts. When an imaging part is selected, only the selected imaging part remains on the screen.
  • the touch panel 241 displays an input image of the subject's weight.
  • the standard weight is displayed on the touch panel 241 as a default, and the operator increases or decreases it with the “+” and “” buttons, and finally touches the “confirm” button. You can enter your weight.
  • the numeric keypad can be displayed on the touch panel 241 together with the weight display field, and the operator can manually push the weight by touching the numeric keypad.
  • a screen for setting information related to a chemical solution is displayed.
  • the drug is a contrast agent
  • the contrast-containing concentration of the contrast agent is determined by the manufacturer and product number of the contrast agent.
  • the operator touches the button corresponding to the iodine content concentration of the contrast medium to be filled the iodine content concentration is input.
  • a list of manufacturer names and part numbers may be displayed, and the operator may select the manufacturer name and part number from the list.
  • the chemical solution filling apparatus has a database regarding the concentration of the odor containing the correlates with the manufacturer name and product number of the contrast medium.
  • each input item remains displayed on the touch panel 241 screen, and the operator can check the items input so far on the screen.
  • the chemical solution filling device 200 determines whether or not the chemical solution is properly charged as described above. The filling amount of is calculated.
  • the calculated filling amount and the start button are further displayed on the touch panel 241.
  • the operator confirms the displayed filling amount and touches the start button.
  • the filling operation mechanism 220 operates to fill the chemical syringe 500 with the chemical solution.
  • the filling state of the chemical solution it is preferable to display the filling state of the chemical solution on the touch panel 241 so that the operator can visually recognize that the chemical solution is being filled.
  • the display image at that time for example, an image showing how the chemical liquid 500 is filled in the chemical syringe 500, and a numerical value indicating the filling amount of the chemical liquid corresponding to the operation of the filling operation mechanism 220 are shown. And the like, or a combination of these images.
  • a manual operation button is displayed on the initial screen of the touch panel 241 in addition to the type of the chemical syringe 500 described above.
  • the operator touches the manual operation button it shifts to manual operation mode.
  • a numerical value indicating the filling amount to be set is displayed together with the “+” and “” buttons, and the operator touches these buttons appropriately to increase or decrease the numerical value and set the filling amount. To be able to.
  • the filling amount can be set by displaying the numeric keypad instead of the “+” button and the “” button and directly entering the numeric value of the numeric keypad button. After the filling amount is set, the operator touches the start button displayed on the touch panel 241 and this starts the filling operation.
  • an air detection sensor (not shown) is provided in tube 610 connecting chemical solution container 600 and chemical syringe 500 in order to detect the mixing of air into chemical solution syringe 500 during the filling of chemical solution. It is preferable.
  • any type of sensor such as an optical type, an ultrasonic type, or a capacitance type may be used as long as it can detect whether or not air is present in the tube 610. be able to.
  • the air changes in the tube 610, and changes in the characteristics when the air is present, such as optical characteristics such as refractive index, reflectance, transmittance, etc.
  • the presence or absence of air in the tube 610 is detected by detecting the change in the resonance characteristics in the case of the ultrasonic method, and the change in the capacitance in the case of the capacitance type.
  • the touch panel 241 displays a message that the filling of the chemical solution is completed and a confirmation button. The operator confirms the completion of filling with the chemical and touches the confirmation button. Then, the chemical solution filling apparatus 200 writes the input data and the calculated filling amount data into the IC tag 503 of the chemical solution syringe 500.
  • the operator When the data writing is completed, the operator removes the chemical liquid syringe 500 filled with the chemical liquid from the chemical liquid filling apparatus 200 and attaches it to the injection head 110 of the chemical liquid injection apparatus 100. Further, the operator connects the extension tube to the chemical syringe 500 via the connecting tube 530 (directly when only one chemical syringe 500 is attached), and is provided at the end of the extension tube. A catheter is inserted into the subject.
  • the operator selects an injection profile as needed.
  • the injection head 110 reads data recorded on the IC tag 503 of the chemical syringe 500 attached. Based on the data read from the IC tag 503, the chemical injection device 100 injects the chemical so as to inject the chemical according to a predetermined injection profile determined in advance or an injection profile selected by the operator. Determine the conditions.
  • the operator operates the injection start button of the input unit 123.
  • the piston drive mechanism 130 is driven with an operation sequence according to the determined injection conditions, and the drug solution in the drug solution syringe 500 is injected into the subject.
  • injection control unit 121 After injection of the chemical solution, injection control unit 121 writes data indicating that the injection of the chemical solution is completed to IC tag 503 through reader Z writer 140. This is to manage the usage history of the chemical syringe 500.
  • the usage history of the chemical syringe 500 can be substituted by referring to the data written in the IC tag 503 by the chemical filling device 200, so the data to the IC tag 503 by the chemical injection device 100 is also available. The writing of can also be omitted.
  • the usage history of the chemical syringe 500 can be managed by the chemical solution filling apparatus 200 by configuring a database in the chemical solution filling apparatus 200.
  • a signal is sent from the injection control unit 101 of the chemical liquid injection apparatus 100 to the imaging control unit 302 of the CT apparatus 300, and the imaging unit is based on the control signal from the imaging control unit 302. 301 captures a fluoroscopic image of the subject.
  • the image picked up by the CT apparatus 300 is sent to the hospital management server 400 directly or via the drug solution injector 100.
  • the hospital management server 400 records the CT examination result in the database.
  • the injection control unit 101 of the chemical injection device 100 reads out from the reader Z writer 140.
  • Various data, chemical injection time, injection speed, injection pressure, etc. are selected and sent to the hospital management sano OO. Therefore, in the database of the hospital management server 400, the injection condition of the chemical solution is recorded together with the CT test result.
  • CT imaging condition data (such as radiation conditions and exposure conditions such as radiation irradiation timing) is transmitted from the CT apparatus 300 to the chemical injection apparatus 100, and the chemical injection apparatus 100 transmits to the hospital management server 400.
  • the above imaging condition data may be added as data to be performed.
  • the CT imaging condition data may be transmitted directly from the CT apparatus 300 to the hospital management server 400.
  • the chemical liquid filling device 200 calculates the filling amount of the chemical liquid into the chemical syringe 500 using the data relating to the inspection conditions, and the chemical liquid syringe 500 is filled with the necessary amount of the chemical liquid. Therefore, the waste of chemicals can be eliminated.
  • the amount of the chemical liquid filled in the chemical syringe 500 is written to the IC tag 503 provided in the chemical syringe 500, and the chemical injection device 100 is configured to read the data written to the IC tag 503. ing. Therefore, the chemical injection device 100 does not need to calculate the injection amount of the chemical solution, and therefore the operator does not need to input data necessary to calculate the injection amount into the chemical injection device 100. In this way, by using the data used to fill the chemical liquid syringe 500 with the chemical liquid for the chemical liquid injection by the chemical liquid injection device 100, the work burden on the operator can be greatly reduced.
  • all the data necessary for calculating the amount of the chemical liquid to be filled in the chemical liquid syringe 500 by the chemical liquid filling device 200 is input from the data written in the IC tag 503 and the input unit 240.
  • a part of these data is recorded in the hospital management Sano 400 database, and if necessary, the hospital management Sano 400 is recorded.
  • the medical solution filling device 200 and the hospital management server 400 may be connected so as to be able to communicate with each other so that these data can be read out (shown by a one-dot chain line in FIG. 1).
  • the amount of data written to the IC tag 503 and the data input operation by the operator can be reduced.
  • Data that can be prepared as a database is data that can also specify the data power when certain data is known.
  • data In the case of syringe data, if the unique identification number (for example, product number and serial number) of the chemical syringe 500 is known, other data can be identified from the unique identification number.
  • the unique identification number for example, product number and lot number
  • the other data can also identify the unique identification number power.
  • the medical solution filling device 200 or the chemical solution injection device 100 that is not included in the hospital management server 400 may have a data base for recording data that can also specify the unique identification number power.
  • the hospital management Sano 00 records not only data on the subject but also data on each equipment such as the chemical injection device 100, the chemical filling device 200, and the CT device 300. It becomes possible.
  • the usage history of the chemical syringe 500 can also be managed by the hospital management Sano 00.
  • the chemical solution filling device 200 serves as a data transmission / reception unit in addition to the reader Z writer 230, as shown in FIG. It can be set as the structure which further has.
  • the hospital management server 400 (see FIG. 1) is connected via an interface 260 so that data can be transmitted and received.
  • connection method between the hospital management server 400 and the drug solution filling apparatus 200 may be a wired connection or a wireless connection.
  • wired connection for example, a cable connector can be used as the interface 260.
  • wireless connection for example, a wireless data communication device can be used as the interface 260.
  • the calculation unit 212 also has the function of a determination unit. Therefore, the data read by the reader Z writer 230 and the data input from the input unit 240 are sent to the calculation unit 212, where the suitability of the chemical solution filling is determined and the filling amount is calculated.
  • the data sent to the calculation unit 212 includes at least one of a unique identification number of the syringe and a unique identification number of the drug solution.
  • the calculation unit 212 calls the data corresponding to the sent unique identification number from the hospital management Sano 00 via the interface 260 and uses it for calculating the filling amount. Since other processes in the filling control unit 210 are the same as those in the case of FIG. 2, the description thereof is omitted here.
  • the filling amount of the chemical solution by the chemical solution filling device 200 is shown in the force database 214 that shows an example obtained by the calculation in the calculation unit 212.
  • the calculation unit 212 can obtain the filling amount of the chemical solution only by referring to the database 214 instead of the calculation.
  • FIG. 7 is a diagram showing an overall configuration of a fluoroscopic imaging system according to the second embodiment of the present invention.
  • FIG. 8 is a block diagram of the chemical solution filling apparatus shown in FIG. 7
  • FIG. 9 is a block diagram of the chemical solution injection apparatus shown in FIG.
  • the same components as those in the first embodiment are denoted by the same reference numerals as those used in the first embodiment, and detailed description thereof is omitted.
  • an interface for connecting the chemical liquid injector 100 to the hospital management server 400 so as to be communicable is omitted.
  • a barcode 504 is provided in the chemical syringe 500 as a data carrier. Barcode 504 contains syringe data, and the recorded data cannot be changed.
  • the chemical filling device 200 has a reader 270 for reading data recorded on the barcode 504.
  • the chemical injection device 100 also has a reader 150 for reading data recorded in the barcode 504.
  • each of the chemical solution filling device 200 and the chemical solution injection device 100 has interfaces 280 and 160 as data transmission / reception units, and the chemical solution filling device 200 and the chemical solution injection device 100 are connected via these interfaces 280 and 160, respectively. Data is sent and received between them.
  • the connection method between the chemical solution filling device 200 and the chemical solution injection device 100 may be wired connection or wireless connection.
  • wired connection for example, cable connectors can be used as the interfaces 280 and 160.
  • wireless connection for example, a wireless data communication device can be used as the interfaces 280 and 160.
  • the syringe data read by the reader 270 is sent to the calculation unit 212. Based on the syringe data sent from the reader 270 and the input data of the input unit 240, the calculation unit 212 determines the suitability of the chemical solution filling and calculates the filling amount. When the filling amount is calculated, the calculation unit 212 sends the syringe data read by the reader 270, the data inputted from the input unit 240, and the calculated filling amount data via the interface 280 to the chemical solution injection device 100. Send to.
  • the chemical liquid injector 100 receives the data via the data force interface 160 transmitted from the chemical liquid filler 200 and sends it to the injection controller 121.
  • the chemical syringe 500 filled with the chemical solution by the chemical solution filling apparatus 200 is removed from the chemical solution filling apparatus 200 and attached to the chemical solution injection apparatus 100.
  • the reader 150 reads the syringe data from the bar code 504 provided on the chemical syringe 500.
  • the syringe data read by the reader 150 is sent to the injection control unit 121.
  • the injection control unit 121 compares the syringe data sent from the reader 150 with the syringe data sent from the drug solution filling apparatus 200 via the interface 160. If the two syringe data are different as a result of the comparison, a warning is given that the chemical syringe 500 attached to the chemical injector 100 is different. If both syringe data match, the injection condition of the chemical solution is determined as in the first embodiment, and the operation according to the determined injection condition is performed. The piston drive mechanism 130 is controlled so that the piston drive mechanism 130 operates in the sequence.
  • the chemical solution injector 100 reads the syringe data of the actually installed chemical solution syringe 500, the chemical solution can be injected under injection conditions corresponding to the actually installed chemical solution syringe 500. . As a result, it is possible to prevent the chemical solution from being injected into the subject under an incorrect injection condition.
  • a two-dimensional code can be used as the force data carrier using the bar code 504 as the data carrier.
  • the data chemical liquid filling device 200 and the chemical liquid injection device 100 do not need to have the readers 270 and 150. In that case, of course, a data carrier is also unnecessary, and instead of reading the unique identification number of the chemical syringe 500 with the readers 270 and 150, the operator can input the input unit 240 of the chemical filler 200 and the operation panel of the chemical injector 100. Enter the unique identification number from 103.
  • the drug solution filling device 200 and the hospital management server 400 can be connected to each other so as to be able to communicate with each other (one point in Fig. 7). (Indicated by a chain line).
  • the chemical filling device 200 is connected to the hospital management server 400 in addition to the interface 280 for data communication with the chemical injection device 100 (see FIG. 7). It has an interface 260 for data communication.
  • the chemical solution injection device 100 determines the injection condition of the chemical solution.
  • the chemical solution filling apparatus 200 can also determine the injection condition.
  • the data necessary to determine the injection conditions is obtained from the chemical injection device 100.
  • This is a method of transmitting to the chemical solution filling apparatus 200 via the hospital management server 400.
  • This method can be used when data can be added or rewritten like data carrier force IC tag provided in chemical syringe 500, and when data can be added or rewritten like barcode. Any deviation can be applied.
  • the second method is a method of transmitting data necessary for determining injection conditions from the chemical solution injection device 100 to the chemical solution filling device 200 via a data carrier provided in the chemical solution syringe 500.
  • This method can be applied only when data can be added or rewritten, such as a data carrier force IC tag provided in the chemical syringe 500.
  • the chemical injection profile is set and set in the chemical injection device 100.
  • the hospital management Sano 00 holds the examination condition including the sent infusion profile as a part of the chart information.
  • the chemical filling apparatus 200 receives data on the examination conditions from the hospital management server 400, and determines the injection condition of the chemical liquid by the chemical injection apparatus 100 in addition to the filling amount of the chemical liquid based on the received data.
  • the chemical solution filling apparatus 200 fills the chemical solution syringe 500 with the chemical solution according to the determined filling amount.
  • the data carrier can be additionally written or rewritten, the determined filling amount and injection conditions are attached, and the data carrier provided in the chemical syringe 500 is additionally written or rewritten.
  • the subsequent procedure may be the same as that of the first embodiment described above except that the injection profile is set by the chemical solution injection device 100.
  • the determined filling amount and injection condition are transmitted from the chemical solution filling apparatus 200 to the chemical solution injection apparatus 100 via the hospital management server 400.
  • the subsequent procedure may be the same as that of the second embodiment described above, except that the injection profile is set by the chemical solution injection device 100.
  • the chemical liquid syringe 500 is attached to the chemical liquid injection apparatus 100.
  • a chemical injection profile is set in the chemical injection device 100, and the set injection profile is written to the data carrier of the chemical syringe 500.
  • the chemical solution 500 is mounted on the chemical filling device 200. Subsequent procedures may be the same as those in the first embodiment described above, except that after the chemical solution is filled in the chemical solution syringe 500, an injection profile is set by the chemical solution injection device 100.
  • the chemical injection device 100 has a plurality of types of injection profiles, and the injection profile used when determining the injection conditions in the chemical solution filling device 200 may be changed.
  • the injection profile is changed, the injection condition of the chemical solution may also change. Therefore, in this case, before injecting the chemical solution, the injection profile is set again in the chemical injection device 100, and the chemical injection device 100 sets the data carrier provided in the chemical syringe 500 according to the reset injection profile.
  • the injection conditions sent from hospital management Sano 00 can be changed.
  • the 1S invention described taking the X-ray CT apparatus as an example of the imaging apparatus is an MRI apparatus, PET apparatus, ultrasonic diagnostic apparatus, CT angio apparatus, MRA apparatus, etc. The same can be applied. Also in these imaging apparatuses, a contrast medium or physiological saline suitable for each can be used as the chemical solution.
  • conventional hospital management systems include the medical information system “HIS” (Hospital Information System), which accepts and accounts for outpatients, and the radiological information system “RIS” (Radiology) in the radiation department.
  • HIS Medical Information System
  • RIS Radiological information system
  • the HIS is an administrative system for image data server management, reception work, and medical expenses
  • the RIS is a system for radiological examination and medical care.
  • the hospital management server is preferably a part of any of these HIS, RIS, and in-hospital information systems that link these.

Abstract

Selon l'invention, un système de remplissage et d'injection de liquide chimique comprend un dispositif de remplissage de liquide chimique (200) et un dispositif d'injection de liquide chimique (100). Le dispositif de remplissage de liquide chimique (200) calcule la quantité d'un liquide chimique à amener dans une seringue de liquide chimique vide (500) et à la remplir avec le liquide chimique en fonction de la quantité calculée de remplissage. Ce dispositif de remplissage de liquide chimique (200) est pourvu d'un lecteur/scripteur (230) pour étiquette CI (503) prévue sur la seringue (500). Dans cette étiquette CI (503), est enregistré un numéro d'identification unique à la seringue (500), et le dispositif de remplissage de liquide (200) ajoute la quantité calculée de remplissage à l'étiquette CI (503). Le dispositif d'injection de liquide chimique (100) comporte également un lecteur/scripteur (140) pour étiquette CI (503) et détermine les conditions d'injection du liquide chimique sur la base des données lues de l'étiquette CI (503).
PCT/JP2007/063588 2006-07-06 2007-07-06 Système de remplissage et d'injection de liquide chimique, et dispositif de remplissage associé WO2008004670A1 (fr)

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JP2012034729A (ja) * 2010-08-04 2012-02-23 Nemoto Kyorindo:Kk 携帯型注入装置及び携帯型注入装置の制御方法
JP2014132991A (ja) * 2013-01-10 2014-07-24 Sumitomo Heavy Ind Ltd 放射性薬剤製造システム用カセット及び放射性薬剤製造システム
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US11883633B2 (en) 2008-05-20 2024-01-30 Avant Medical Corp. Autoinjector system
US10792426B2 (en) 2008-05-20 2020-10-06 Avant Medical Corp. Autoinjector system
US10864324B2 (en) 2008-05-20 2020-12-15 Avant Medical Corp. Autoinjector system
US11724032B2 (en) 2008-07-23 2023-08-15 Avant Medical Corp. System and method for an injection using a syringe needle
JP2011120847A (ja) * 2009-12-14 2011-06-23 Tosho Inc 薬剤包装装置
JP2012034729A (ja) * 2010-08-04 2012-02-23 Nemoto Kyorindo:Kk 携帯型注入装置及び携帯型注入装置の制御方法
US11419990B2 (en) 2011-04-20 2022-08-23 Amgen Inc. Autoinjector apparatus
JP2019103890A (ja) * 2011-04-20 2019-06-27 アムゲン・インコーポレーテッド 自動式注射装置
JP7278134B2 (ja) 2011-04-20 2023-05-19 アムゲン・インコーポレーテッド 自動式注射装置
US10918805B2 (en) 2011-04-20 2021-02-16 Amgen Inc. Autoinjector apparatus
JP2014132991A (ja) * 2013-01-10 2014-07-24 Sumitomo Heavy Ind Ltd 放射性薬剤製造システム用カセット及び放射性薬剤製造システム
US11020537B2 (en) 2013-03-15 2021-06-01 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
US10786629B2 (en) 2013-03-15 2020-09-29 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
US11944798B2 (en) 2013-03-15 2024-04-02 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
JP2016195829A (ja) * 2016-07-22 2016-11-24 株式会社根本杏林堂 携帯型注入装置及び携帯型注入装置の制御方法
GB2572122B (en) * 2017-02-23 2022-05-11 Smiths Medical Asd Inc Device with identifier
US11783933B2 (en) 2017-02-23 2023-10-10 Smiths Medical Asd, Inc. Device with identifier
JP7162604B2 (ja) 2017-09-29 2022-10-28 テルモ株式会社 医療用ポンプ、医療用ポンプの制御方法、及び医療用ポンプシステム
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JPWO2019064952A1 (ja) * 2017-09-29 2020-09-10 テルモ株式会社 医療用ポンプ、医療用ポンプの制御方法、及び医療用ポンプシステム

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