WO2007070643A3 - Compositions and methods for treating dermatological conditions - Google Patents

Compositions and methods for treating dermatological conditions Download PDF

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Publication number
WO2007070643A3
WO2007070643A3 PCT/US2006/047747 US2006047747W WO2007070643A3 WO 2007070643 A3 WO2007070643 A3 WO 2007070643A3 US 2006047747 W US2006047747 W US 2006047747W WO 2007070643 A3 WO2007070643 A3 WO 2007070643A3
Authority
WO
WIPO (PCT)
Prior art keywords
volatile solvent
drug
solvent system
formulation
volatile
Prior art date
Application number
PCT/US2006/047747
Other languages
French (fr)
Other versions
WO2007070643A2 (en
Inventor
Jie Zhang
Kevin S Warner
Sanjay Sharma
Original Assignee
Zars Inc
Jie Zhang
Kevin S Warner
Sanjay Sharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zars Inc, Jie Zhang, Kevin S Warner, Sanjay Sharma filed Critical Zars Inc
Priority to JP2008545816A priority Critical patent/JP2009519940A/en
Priority to AU2006326388A priority patent/AU2006326388B2/en
Priority to CN2006800525770A priority patent/CN101378729B/en
Priority to CA2633489A priority patent/CA2633489C/en
Priority to EP06847657A priority patent/EP1959929A4/en
Publication of WO2007070643A2 publication Critical patent/WO2007070643A2/en
Publication of WO2007070643A3 publication Critical patent/WO2007070643A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention is drawn to solidifying adhesive formulations, methods of drug delivery, and solidified layers for dermal delivery of a drug which can treat various dermatological conditions, such as a bacterial infection, a virus infection, a fungal infection, alopecia, dermatitis, psoriasis, or photo damaged skin. The formulation can include a drug, a solvent vehicle, and a solidifying agent. The solvent vehicle can include a volatile solvent system including at least one volatile solvent, and a non-volatile solvent system including at least one non-volatile solvent. The non-volatile solvent system can facilitate the delivery of the drug at therapeutically effective rates for sustained period of time. The non-volatile solvent system can also act as a plasticizer for the solidifying agent. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified layer after at least a portion of the volatile solvent system is evaporated.
PCT/US2006/047747 2005-12-14 2006-12-14 Compositions and methods for treating dermatological conditions WO2007070643A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2008545816A JP2009519940A (en) 2005-12-14 2006-12-14 Compositions and methods for treating dermatological conditions
AU2006326388A AU2006326388B2 (en) 2005-12-14 2006-12-14 Compositions and methods for treating dermatological conditions
CN2006800525770A CN101378729B (en) 2005-12-14 2006-12-14 Compositions and methods for treating dermatological conditions
CA2633489A CA2633489C (en) 2005-12-14 2006-12-14 Compositions and methods for treating dermatological conditions
EP06847657A EP1959929A4 (en) 2005-12-14 2006-12-14 Compositions and methods for treating dermatological conditions

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US75052205P 2005-12-14 2005-12-14
US75052405P 2005-12-14 2005-12-14
US75046505P 2005-12-14 2005-12-14
US75063705P 2005-12-14 2005-12-14
US60/750,522 2005-12-14
US60/750,524 2005-12-14
US60/750,637 2005-12-14
US60/750,465 2005-12-14

Publications (2)

Publication Number Publication Date
WO2007070643A2 WO2007070643A2 (en) 2007-06-21
WO2007070643A3 true WO2007070643A3 (en) 2008-05-08

Family

ID=38163526

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/047747 WO2007070643A2 (en) 2005-12-14 2006-12-14 Compositions and methods for treating dermatological conditions

Country Status (6)

Country Link
EP (1) EP1959929A4 (en)
JP (1) JP2009519940A (en)
CN (1) CN101378729B (en)
AU (1) AU2006326388B2 (en)
CA (1) CA2633489C (en)
WO (1) WO2007070643A2 (en)

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US8741333B2 (en) 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for treating dermatitis or psoriasis
ES2407407T3 (en) 2005-06-01 2013-06-12 Glaxosmithkline Intellectual Property Development Limited Vitamin formulation
US20090175810A1 (en) 2008-01-03 2009-07-09 Gareth Winckle Compositions and methods for treating diseases of the nail
CA2730787A1 (en) 2008-07-16 2010-01-21 David M. Cohen Topical drug delivery system
US20100160368A1 (en) 2008-08-18 2010-06-24 Gregory Jefferson J Methods of Treating Dermatological Disorders and Inducing Interferon Biosynthesis With Shorter Durations of Imiquimod Therapy
KR20110067145A (en) 2008-10-03 2011-06-21 넥스메드 홀딩스 인코포레이티드 Stabilized composition for treating psoriasis
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US8735422B2 (en) * 2009-02-06 2014-05-27 Skinvisible Pharmaceuticals, Inc. Cationic pharmaceutically active ingredient containing composition, and methods for manufacturing and using
WO2010093992A1 (en) 2009-02-13 2010-08-19 Topica Pharmaceuticals, Inc Anti-fungal formulation
CA2760554A1 (en) 2009-05-01 2010-11-04 Signal Investment And Management Co. Moisturizing antimicrobial composition
EA025993B1 (en) 2009-07-13 2017-02-28 Медисис Фармасьютикал Корпорейшн Lower dosage strength imiquimod formulations and short dosing regimens for treating genital and perianal warts
GB2479544A (en) * 2010-04-13 2011-10-19 Brands Worldwide Holdings I P Pty Ltd Film forming material to reduce skin irritation due to friction
US8039494B1 (en) 2010-07-08 2011-10-18 Dow Pharmaceutical Sciences, Inc. Compositions and methods for treating diseases of the nail
WO2012107564A1 (en) 2011-02-10 2012-08-16 Moberg Derma Ab Novel formulations for dermal, transdermal and mucosal use 1
EP2510930A1 (en) 2011-04-15 2012-10-17 Bionanoplus, S.L. Nanoparticles comprising half esters of poly (methyl vinyl ether-co-maleic anhydride) and uses thereof
CN104321323B (en) * 2012-01-03 2016-10-12 西尔秀特斯公司 Carbocyclic nucleoside and medical usage thereof and compositions
CN103191408B (en) * 2013-04-19 2014-02-12 江苏迪沃生物制品有限公司 Medicine composition and gel for treating colpitis and applications thereof
CN104138352B (en) * 2013-04-19 2018-02-27 江苏知原药业有限公司 Calcipotriol non-aqueous gel
CN103301089B (en) * 2013-07-08 2015-01-07 广东彼迪药业有限公司 Famciclovir capsule preparation and preparation method thereof
MY179756A (en) 2013-10-03 2020-11-12 Dow Pharmaceutical Sciences Stabilized efinaconazole formulations
CN103589886A (en) * 2013-11-17 2014-02-19 湖南金马铝业有限责任公司 Adhesive for silicon carbide aluminum matrix composite produced with powder metallurgic method
JP6611014B2 (en) 2013-11-22 2019-11-27 ボシュ ヘルス アイルランド リミテッド Anti-infection method, anti-infection composition, and anti-infection device
CN103933545B (en) * 2014-05-14 2015-06-17 深圳市红瑞生物科技有限公司 Medicine for treating fungal infection and preparation method thereof
US9592188B2 (en) 2014-05-22 2017-03-14 Yansong Liu Method of treating or reducing the severity of dermatological conditions
FR3025718A1 (en) 2014-09-15 2016-03-18 Septeos POTENTIAL ANTIMICROBIALS
CN107148284A (en) * 2015-01-30 2017-09-08 株式会社梅德瑞科思 aqueous external preparation
CN109071750B (en) 2016-03-08 2022-08-02 生活实验公司 Long-lasting cosmetic composition
CN106074732A (en) * 2016-07-21 2016-11-09 吕令中 A kind of antipsoriatics thing and preparation method thereof
CN108186554B (en) * 2016-12-08 2022-12-09 海思科制药(眉山)有限公司 Desonide cream medicinal composition and preparation method thereof
WO2018133010A1 (en) * 2017-01-19 2018-07-26 广东东阳光药业有限公司 Transdermal absorption preparation and method for preparing same
CN107261109A (en) * 2017-07-18 2017-10-20 华若延 It is a kind of to be used to treat pharmaceutical composition of diaper rash and preparation method thereof
WO2019022249A1 (en) * 2017-07-28 2019-01-31 国立大学法人九州大学 Transdermal absorption composition with controlled release of minoxidil
JP7244495B2 (en) 2017-09-13 2023-03-22 リビング プルーフ インコーポレイテッド Long lasting cosmetic composition
CN111065665B (en) 2017-09-13 2023-03-17 生活实验公司 Color protectant compositions
CN107823070A (en) * 2017-12-14 2018-03-23 柳州市柳科科技有限公司 A kind of hand lotion and preparation method thereof
CN108904445A (en) * 2018-08-06 2018-11-30 江苏知原药业有限公司 Its salts nano suspending liquid
CN110200887A (en) * 2019-07-01 2019-09-06 安徽大学 A kind of multiple-effect hair growing gel and preparation method thereof
KR102356831B1 (en) * 2021-04-15 2022-02-08 주식회사 바이오빌리프 Pharmaceutical compositions for topical administration in the form of solution and processes for the preparation thereof

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Patent Citations (2)

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US6395955B1 (en) * 1998-06-29 2002-05-28 The Procter & Gamble Company Diaper including feces modification agent
US20040143026A1 (en) * 2002-12-31 2004-07-22 Shah Kishore R. Bioadhesive hydrophilic composition for treatment of mammalian skin

Non-Patent Citations (1)

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Title
See also references of EP1959929A4 *

Also Published As

Publication number Publication date
AU2006326388B2 (en) 2013-01-24
CN101378729A (en) 2009-03-04
EP1959929A2 (en) 2008-08-27
EP1959929A4 (en) 2012-08-15
CA2633489A1 (en) 2007-06-21
CA2633489C (en) 2013-09-24
JP2009519940A (en) 2009-05-21
WO2007070643A2 (en) 2007-06-21
CN101378729B (en) 2013-09-11
AU2006326388A1 (en) 2007-06-21

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