WO2007049805A8 - 合成リポペプチドおよびその医薬用途 - Google Patents

合成リポペプチドおよびその医薬用途

Info

Publication number
WO2007049805A8
WO2007049805A8 PCT/JP2006/321927 JP2006321927W WO2007049805A8 WO 2007049805 A8 WO2007049805 A8 WO 2007049805A8 JP 2006321927 W JP2006321927 W JP 2006321927W WO 2007049805 A8 WO2007049805 A8 WO 2007049805A8
Authority
WO
WIPO (PCT)
Prior art keywords
lipopeptide
mycoplasma
antibody
synthetic
fam
Prior art date
Application number
PCT/JP2006/321927
Other languages
English (en)
French (fr)
Other versions
WO2007049805A1 (ja
Inventor
Koichi Kuwano
Takashi Shimizu
Original Assignee
Univ Kurume
Koichi Kuwano
Takashi Shimizu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2007542797A priority Critical patent/JPWO2007049805A1/ja
Application filed by Univ Kurume, Koichi Kuwano, Takashi Shimizu filed Critical Univ Kurume
Publication of WO2007049805A1 publication Critical patent/WO2007049805A1/ja
Publication of WO2007049805A8 publication Critical patent/WO2007049805A8/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1253—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/30—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/30—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

現在有効な予防手段がないマイコプラズマ肺炎に対し、ＦＡＭ−２０およびＦＡＭ−５を代表とするマイコプラズマ・ニューモニエ(Mycoplasma pneumoniae)に由来する合成リポペプチド、当該リポペプチドを含有するトールライクレセプターの活性化剤、当該リポペプチドを含有する転写因子誘導剤、当該リポペプチドおよび医薬として許容され得る担体を含有するワクチン組成物などを提供すると共に、当該合成リポペプチドを抗原として調製した抗体、当該抗体を含有するマイコプラズマ感染症の予防または治療剤、当該抗体を用いることを特徴とするマイコプラズマ・ニューモニエの検出方法、マイコプラズマ感染症の診断方法および治療方法などを提供する。
PCT/JP2006/321927 2005-10-26 2006-10-26 合成リポペプチドおよびその医薬用途 WO2007049805A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2007542797A JPWO2007049805A1 (ja) 2005-10-26 2006-09-26 合成リポペプチドおよびその医薬用途

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2005-311966 2005-10-26
JP2005311966 2005-10-26
JP2006-119581 2006-04-24
JP2006119581 2006-04-24

Publications (2)

Publication Number Publication Date
WO2007049805A1 WO2007049805A1 (ja) 2007-05-03
WO2007049805A8 true WO2007049805A8 (ja) 2007-07-05

Family

ID=37967906

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2006/321927 WO2007049805A1 (ja) 2005-10-26 2006-10-26 合成リポペプチドおよびその医薬用途

Country Status (2)

Country Link
JP (1) JPWO2007049805A1 (ja)
WO (1) WO2007049805A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2009142086A1 (ja) * 2008-05-23 2011-09-29 学校法人 久留米大学 マイコプラズマ感染症用ワクチン組成物
EP2338521A1 (en) * 2009-12-28 2011-06-29 Helmholtz-Zentrum für Infektionsforschung GmbH Lipopeptide- and lipoprotein-conjugates and its use
WO2012003810A1 (zh) * 2010-07-09 2012-01-12 中国科学院上海巴斯德研究所 Foxp3及调节性ｔ细胞的调节因子及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006126719A1 (ja) * 2005-05-25 2006-11-30 Kurume University Ｔｌｒ活性化剤およびワクチン組成物

Also Published As

Publication number Publication date
JPWO2007049805A1 (ja) 2009-04-30
WO2007049805A1 (ja) 2007-05-03

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