WO2007042410A1 - Preparation de nettoyage desodorisante - Google Patents

Preparation de nettoyage desodorisante Download PDF

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Publication number
WO2007042410A1
WO2007042410A1 PCT/EP2006/066878 EP2006066878W WO2007042410A1 WO 2007042410 A1 WO2007042410 A1 WO 2007042410A1 EP 2006066878 W EP2006066878 W EP 2006066878W WO 2007042410 A1 WO2007042410 A1 WO 2007042410A1
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WO
WIPO (PCT)
Prior art keywords
preparation
acid
dimethyl
acetate
cosmetic
Prior art date
Application number
PCT/EP2006/066878
Other languages
German (de)
English (en)
Inventor
Christian Frese
Stephan Ruppert
Cornelia Meier-Zimmerer
Heike FÖLSTER
Original Assignee
Beiersdorf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beiersdorf Ag filed Critical Beiersdorf Ag
Publication of WO2007042410A1 publication Critical patent/WO2007042410A1/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/736Chitin; Chitosan; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00Anti-perspirants or body deodorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair

Definitions

  • the present invention relates to a cosmetic cleansing preparation
  • a cosmetic cleansing preparation comprising a) one or more anionic surfactants, b) chitosan having a molecular weight of 20,000 to 300,000 daltons and a degree of deacetylation of 80-98%.
  • Detergents could be formulated with newly developed synthetic surfactants.
  • a special group of skin cleansing products are the cleansing gels.
  • Cleansing gels contain water, surfactants and gel formers as main components.
  • the surfactants are the detergent-active substances in the cleaning gels. Due to their specific molecular structure, each with a hydrophilic (water-attracting) and hydrophobic (water-repellent) grouping in the same molecule, they reduce the surface tension of the water, which facilitates soil removal. Depending on the state of charge, a distinction is made between anionic, cationic, amphoteric and nonionic surfactants. Due to their ability to reduce the surface tension of water, surfactants cause frothing of the formulation.
  • the gelling agents form in the cleaning gel a three-dimensional network in which the liquid (usually water) is immobilized.
  • the gelling agents used are usually polymers such as polyacrylates. These become the preparation to be thickened at neutral pH added and then deprotonated by the addition of bases, whereby the preparation is transformed into a viscous gel.
  • a further disadvantage of prior art cleansing gels is the fact that the preparations may cause dehydration of the skin, since the natural, moisturizing, water-binding substances (moisturizing factors) are removed from the skin during the application of the cleansing gel.
  • a well-known cosmetic raw material that reduces the adhesion of bacteria to the skin is chitosan.
  • Chitosan is the partially deacetylated and partially depolymerized derivative of chitin. It arises from the alkaline treatment of chitin.
  • chitin In addition to its anti-adhesive properties, chitosan has the cosmetically interesting properties of being able to act as a film former and moisturizer and thus to produce a pleasant, smooth, relaxed skin sensation.
  • the object of the present invention was moreover to produce a high-foaming cleaning preparation with high cleaning performance, as are typical of formulations with anionic surfactants, and to develop a cleaning preparation which leaves a long-lasting fragrant fragrance after use.
  • ⁇ DE 102 08 550 describes cleaning preparations containing 0.36% chitosan, 1, 25% anionic surfactant, 0.2% perfume, and 1, 25% anionic surfactants.
  • APGs alkyl polyglycosides
  • APGs have, as described for example in DE 196 05 355, the disadvantage of leaving an unpleasant dull skin feeling.
  • a content of 0.2% perfume no sufficient fragrance effect can be achieved.
  • the chitosans used which have a molecular weight of 800,000 to 1,200,000 Da, no longer have an antiadhesive effect on odor-forming bacteria and in the stated use concentration does not have sufficient film-forming and moisturizing action. With a low content of anionic surfactants can no longer produce sufficient foam effect.
  • EP 1 384 404 discloses combinations of anionic surfactants or perfumes with chitosans having a molecular weight of up to 10,000 Da. chitosan are used here as anti-dandruff agents. In the examples listed also anionic surfactants are called in high concentration. Although the claimed oligoaminosaccharides are effective antidandruff agents, they lack the film-forming and moisturizing properties due to their low molecular weight. Moreover, in the examples listed in EP 1384404, no amphoteric surfactants are mentioned which are generally necessary for good foaming power.
  • Reservoirs are stored and mixed together only in the application.
  • a cosmetic cleaning preparation comprising a) one or more anionic surfactants, b) chitosan having a molecular weight of 20,000 to 300,000 daltons and a degree of deacetylation of 80-98%.
  • the chitosan according to the invention has a molecular weight of 50,000 to 200,000 daltons, and particularly preferred if the chitosan according to the invention has a molecular weight of 60,000 to 140,000 daltons.
  • the degree of deacetylation of the chitosan is 92-98%.
  • the molecular weight is determined according to GPC analysis in a 0.1 molar NaCl / 0.1 vol.% Trifluoroacetic acid solution at 23 ° C with a PSS-Novema column (10 ⁇ m, linear, ID 8.0 mm x 300 mm) Flow of 1, 0 ml / min, a sample concentration of 2.0 g / l and an injection volume of 20 ul determined.
  • the degree of deacetylation can be determined by the direct titration method.
  • the cleaning preparation according to the invention is preferably a transparent preparation according to the invention.
  • preparations are considered to be transparent which have a transmission of at least 65% at a wavelength of 420 nm.
  • the transmission according to the invention was determined according to the invention with the device Agilent 8453 diode array spectrometer at a layer thickness of 1 cm. The measurement was carried out in a range of 190 to 1100 nm at intervals of 1 nm and an integration time of 0.5 seconds at room temperature.
  • the transmission of the preparation according to the invention is preferably from 70% to 90% and particularly preferably 80% in each case at a wavelength of 420 nm.
  • the preparation according to the invention comprises the chitosan according to the invention in a concentration of 0.1 to 3% by weight, preferably in a concentration of 0.3 to 2% by weight and more preferably in a concentration of 0.5 to 1 , 2% by weight, based in each case on the total weight of the preparation.
  • Embodiments of the present invention which are advantageous according to the invention are characterized in that the preparation comprises anionic surfactants in a total concentration of 1.5 to 10% by weight, preferably in a total concentration of 2 to 8% by weight and more preferably in a total concentration of 2 to 5% by weight %, in each case based on the total weight of the preparation.
  • the preparation contains sodium lauryl ether sulfate as an anionic surfactant.
  • the cosmetic preparation according to the invention is characterized in embodiments advantageous according to the invention in that the preparation according to the invention advantageously amphoteric surfactants in a concentration of 2 to 25% by weight, preferably in a concentration of 5 to 20% by weight and more preferably in a concentration of 8 to 15% by weight, based in each case on the total weight of the preparation.
  • the preparation contains betaines and / or amphoacetates as amphoteric surfactants.
  • the preparation of the invention perfumes in a concentration of 0.4 to 2% by weight, preferably in a concentration of 0.5 to 1, 5% by weight and particularly preferably in a concentration of 0.6 to 1 % By weight, based in each case on the total weight of the preparation.
  • the perfume substances be one or more compounds selected from the group of the compounds methylabietate, 1,4-dioxacycloheptadecane-5,17-dione, 3,7-dimethyl-1,6-nonadien-3-ol,
  • Eucalyptus oil (Eucalyptus Globulus)
  • Lavender oil (Lavandula hybrida L.)
  • the preparation according to the invention contains alkylpolyglycosides (APGs) in a concentration of at most 1% by weight, based on the total weight of the preparation.
  • APGs alkylpolyglycosides
  • Embodiments of the present invention which are preferred according to the invention are characterized in that the preparation is free of alkylpolyglycosides (APG).
  • the preparation comprises a solubilizer in a concentration of 0.1 to 5% by weight, preferably in a concentration of 0.5 to 3% by weight and more preferably in a concentration of 1 to 2 % By weight, based in each case on the total weight of the preparation.
  • the preparation comprises one or more solubilizers selected from the group of compounds a) the fatty acid ethers of fatty alcohols and ethylene glycols and / or propylene glycols one or more ethylene glycol and / or propylene glycol units b) contains adducts of ethylene oxide with triglycerides ,
  • coceth-7 PPG-1-PEG-9 lauryl glycol ether and PEG-40 hydrogenated castor oil is used as a solubilizer. It is particularly preferred according to the invention to use coceth-7, PPG-1-PEG-9 lauryl glycol ether, PEG-40 hydrogenated castor oil and water in a mixing ratio of 25-50 / 25-50 / 10 -20 / 5-10.
  • the solubilizer particularly preferred according to the invention can be obtained from Cognis under the name Eumulgin HPS.
  • the cleaning gel has a pH of pH 6 to pH 8.
  • Embodiments of the present invention which are preferred according to the invention are characterized in that the preparation contains one or more preservatives in a concentration of 0.1 to 2.0% by weight and more preferably of 0.2 to 1.2% by weight, based in each case on Total weight of the preparation contains.
  • the cleansing gel according to the invention comprises one or more complexing agents in a total concentration of 0.1 to 2.0% by weight and particularly preferably in a concentration of 0.2 to 1.0% by weight, in each case based on the total weight of the preparation contains.
  • the complexing agent (s) can advantageously be selected from the group of the customary compounds, preference being given to at least one substance selected from the group consisting of tartaric acid and its anions, citric acid and its anions, aminopolycarboxylic acids and their anions (such as, for example, ethylenediaminetetraacetic acid (EDTA) and their anions, Nitrilotriacetic acid (NTA) and its anions, hydroxyethylenediaminotriacetic acid (HOEDTA) and its anions, diethylenetaminopentaacetic acid (DPTA) and their anions, trans-1,2-diaminocyclohexanetetraacetic acid (CDTA) and their anions).
  • EDTA ethylenediaminetetraacetic acid
  • NTA Nitrilotriacetic acid
  • HOEDTA hydroxyethylenediaminotriacetic acid
  • DPTA diethylenetaminopentaacetic acid
  • CDTA trans-1,2-diamin
  • hydroxyethylenediaminotriacetic acid and, in particular, the sodium salt of hydroxyethylenediaminotriacetic acid (NassHEDTA) as complexing agent it is particularly preferred to use hydroxyethylenediaminotriacetic acid and, in particular, the sodium salt of hydroxyethylenediaminotriacetic acid (NassHEDTA) as complexing agent.
  • NassHEDTA sodium salt of hydroxyethylenediaminotriacetic acid
  • the preparation according to the invention contains gelling agents.
  • the gelling agents are preferably selected from the group of the compounds polyacrylates, acrylate-alkyl acrylate copolymers, gums, cellulose derivatives, sheet silicates, PEG-120 methyl glucose dioleate, silica gels and / or starch derivatives.
  • Embodiments of the present invention which are advantageous according to the invention are characterized in that the preparation comprises polyacrylates in a concentration of 0.1 to 5% by weight, preferably in a concentration of 0.2-3% by weight and more preferably in a concentration of 0.3 -1, 5% by weight, each based on the total weight of the preparation contains.
  • Polyacrylates which are advantageous according to the invention are polymers of acrylic acid, in particular those selected from the group of the so-called carbomers or carbopols (Carbopol® is actually a registered trademark of the B.F. Goodrich Company). Polyacrylates are compounds of the general structural formula
  • the group of polyacrylates also includes acrylate-alkyl acrylate copolymers, for example those which have the following structure:
  • R ' represents a long-chain alkyl radical and x and y represent numbers which symbolize the respective stoichiometric proportion of the respective comonomers.
  • Examples of advantageous carbopols are the types 907, 910, 934, 940, 941, 951, 954, 980, 981, 1342, 1382, 2984 and 5984 or else the types ETD (E_asy-to-disperse) 2001, 2020, 2050, Aqua -SF1 wherein these compounds can be present individually or in any desired combinations with one another.
  • ETD E_asy-to-disperse
  • acrylate-alkyl acrylate copoly- mers comparable copolymers of C O - o 3-alkyl acrylates and one or more monomers of acrylic acid, methacrylic acid or esters thereof.
  • the INCI name for such compounds is "Acrylates / C 10-30 Alkyl Acrylate Crosspolymer.”
  • Pemulen TR1 and Pemulen TR2 from the BF Goodrich Company.
  • gel formers are used in the preparations according to the invention.
  • these may, for example, be advantageously selected from further compounds of the group of gums (for example gum arabic, locust bean gum, tragacanth, karaya, guar gum, pectin, gellan gum, carrageenan, agar, algins, chondrus, xanthan gum).
  • gums for example gum arabic, locust bean gum, tragacanth, karaya, guar gum, pectin, gellan gum, carrageenan, agar, algins, chondrus, xanthan gum.
  • derivatized gums such as e.g. Hydroxypropyl guar (Jaguar® HP 8).
  • polysaccharides and derivatives are e.g. Hyaluronic acid, chitin and chitosan, chondroitin sulfates, starch and starch derivatives as gelling agents advantageous according to the invention.
  • cellulose derivatives are e.g. Methylcellulose, carboxymethylcellulose, hydroxyethylcellulose, hydroxypropylmethylcellulose advantageous gel formers according to the invention.
  • layered silicates are naturally occurring and synthetic clays such as e.g. Montmorillonite, bentonite, hectorite, laponite, magnesium aluminum silicates such as Veegum®. These may be used as such or in modified form as gelling agents, e.g. Stearylalkonium hectorites.
  • PEG-120 methyl glucose dioleate (INCI PEG-120 methyl glucose dioleate) can also be used as gel former preferred according to the invention. According to the invention, this can advantageously be contained in this at a concentration of from 0.01 to 1% by weight, based on the total weight of the preparation.
  • one or more pregelatinized, crosslinked starch derivatives are present in a concentration of 0.1 to 20% by weight, preferably in a concentration of 0.3 to 15% by weight and most preferably in a concentration from 0.5 to 10% by weight, based on the total weight of the preparation, of the preparation according to the invention, the use of hydroxypropyldistarch phosphate. (eg Structure XL from National Starch) is particularly preferred.
  • the cleansing gel according to the invention comprises abrasives (e.g.
  • Cleansing gel contains one or more dyes.
  • dyes in particular all known, water-soluble and approved for the cosmetics dyes can be added to the preparation.
  • Opacifying agents / pearlescing agents or mixtures which are advantageous according to the invention include:
  • ⁇ styrene / acrylate copolymers such as Acusol OP 301 from Rohm & Haas
  • the aqueous phase of the cleaning gels according to the invention may advantageously contain customary cosmetic auxiliaries, for example alcohols, in particular those of low C number, preferably ethanol and / or isopropanol, diols or polyols of low C number and their ethers, preferably propylene glycol, glycerol, butylene glycol, ethylene glycol , Ethylene glycol monoethyl or monobutyl ether, propylene glycol monomethyl, monoethyl or monobutyl ether, diethylene glycol monomethyl or monoethyl ether and analogous products, polymers, foam stabilizers, electrolyte, pearlescent agents, antidandruff active ingredients, plant extracts, vitamins, active ingredients, film formers (all can be used in cosmetics used film-forming). Particularly advantageous preparations are also obtained when antioxidants are used as additives or active ingredients.
  • customary cosmetic auxiliaries for example alcohols, in particular those of low C number, preferably ethanol and
  • active ingredients in the context of the present invention are natural active ingredients and / or derivatives thereof, such as.
  • Another advantageous active ingredient according to the invention is, for example, polidocanol.
  • the amount of the active ingredients (one or more compounds) in the preparations according to the invention is preferably 0.001 to 30 wt .-%, particularly preferably 0.05 to 20 wt .-%, in particular 0.1 to 10 wt .-%, based on the Total weight of the preparation.
  • the preparations contain one or more film formers.
  • the film formers according to the invention can advantageously be used in a concentration of 0.01 to 5% by weight, preferably in a concentration of 0.05 to 2% by weight and very particularly preferably in a concentration of 0.01 to 1% by weight, in each case be used based on the total weight of the preparation.
  • Film formers which are advantageous according to the invention can be selected from the compounds listed in the table.
  • Guar gum derivatives especially guar hydroxypropylammonium chloride
  • Nonionic poly-N-vinylpyrrolidone / polyvinyl acetate copolymers eg Luviskol VA 64W, BASF
  • anionic acrylate copolymers eg Luviflex soft, BASF
  • amphoteric amide / acrylate / methacrylate copolymers eg Amphomer, National Starch
  • Preferred film formers according to the invention are Polyquaternium-10, Polyquaternium-22 and Polyquaternium-44 and Jaguar Excel.
  • Polyquaternium-10 e.g., Ucare Polymer JR-125 and Ucare Polymer JR-400, Amerchol
  • Jaguar Excel is particularly preferred in the present invention.
  • Polyquaternium-10 in a concentration of 0.01 to 2% by weight, preferably in a concentration of 0.05 to 1.5% by weight and particularly preferably from 0.1 to 1.0% by weight, based in each case Total weight of the preparation to use.
  • quaternized guar in a concentration of 0.01 to 3% by weight, preferably in a concentration of 0.05 to 2% by weight and particularly preferably in a concentration of 0.01 to 1% by weight, respectively based on the total weight of the preparation to use.
  • one or more compounds selected from the group of guar hydroxypropyltrimethylammonium chlorides which belong to the class of galactomannan 2-hydroxypropyltrimethylammonium chloride ethers having an average molecular weight of 600,000 to 2,000,000 and a charge density of from 0.4 to 1.0 are selected as quaternized guar own meq / g.
  • guaran- Hydroxypropyltrimethylammoniumchloride selected from the Jaguar series, with Jaguar Excel the company Rhodia is very particularly preferred according to the invention.
  • the preparation according to the invention can advantageously be used as a shower gel, shower or bath, shampoo, facial cleanser or intimate cleanser.
  • the preparation according to the invention is in the form of a shampoo, this may advantageously contain anti-dandruff active ingredients.
  • anti-dandruff agents e.g. Climbazole and octopirox are used.
  • the preparation according to the invention is particularly suitable for people suffering from acne or foot odor as well as for atopic people.
  • the invention also provides a process for preparing a cosmetic preparation according to any one of the preceding claims which comprises the following steps: a) dissolving the chitosan in water by adding an acid selected from the acids hydrochloric acid, phosphoric acid, formic acid, acetic acid, lactic acid, citric acid, glycolic acid , Malonic acid, benzoic acid, sorbic acid, adipic acid and b) mix with the separately prepared surfactant phase and a separately prepared perfume phase.
  • an acid selected from the acids hydrochloric acid, phosphoric acid, formic acid, acetic acid, lactic acid, citric acid, glycolic acid , Malonic acid, benzoic acid, sorbic acid, adipic acid
  • the process according to the invention is preferably carried out at room temperature (about 20 ° C.).
  • a cosmetic preparation is also prepared by the process.
  • the preparation according to the invention is stored in a tube, a pump dispenser or a bottle and applied out of it.
  • Such packaging containers are preferably transparent according to the invention.
  • tubes, pump dispensers or bottles containing a preparation according to the invention in the context of this disclosure also called “cosmetic"
  • transparent packaging containers according to the invention are preferred.
  • a cosmetic comprising a preparation according to the invention and a transparent packaging container of polyethylene terephthalate (PET). It is also advantageous in the context of the present invention to apply the cleansing gel according to the invention to a carrier material (for example a cloth, harid, Wattebausch). Such carriers are preferably made of viscose, cotton and / or polyester fibers.
  • a carrier material for example a cloth, Päd, Wattebausch
  • a cleansing gel according to the invention, wherein the carrier material is preferably composed of viscose, cotton and / or polyester fibers.
  • Phases 1 to 3 are stirred at room temperature until clear solutions have formed. Subsequently, phases 1 and 2 are added to phase 3 with stirring.
  • Ad 100 refers to all 3 phases, not to phase 3!

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

La présente invention concerne une préparation de nettoyage cosmétique contenant a) un ou plusieurs tensioactifs anioniques, b) du chitosane ayant une masse molaire de 200000 à 300000 dalton et un degré de désacétylation de 80-98 %.
PCT/EP2006/066878 2005-10-07 2006-09-29 Preparation de nettoyage desodorisante WO2007042410A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200510048776 DE102005048776A1 (de) 2005-10-07 2005-10-07 Desodorierende Reinigungszubereitung
DE102005048776.9 2005-10-07

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Publication Number Publication Date
WO2007042410A1 true WO2007042410A1 (fr) 2007-04-19

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PCT/EP2006/066878 WO2007042410A1 (fr) 2005-10-07 2006-09-29 Preparation de nettoyage desodorisante

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012140536A (ja) * 2010-12-28 2012-07-26 Kao Corp 香料組成物

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008018789A1 (de) * 2008-04-11 2009-10-15 Beiersdorf Ag Parfümierte kosmetische Zubereitung mit Citronellol
DE102008001770A1 (de) 2008-05-13 2009-11-19 Beiersdorf Ag Kosmetische Zubereitungen gegen Kopfhautschuppen
DE102008001726A1 (de) 2008-05-13 2009-11-19 Beiersdorf Ag Antimikrobielle kosmetische zubereitung

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19701417C1 (de) * 1997-01-17 1998-04-09 Wella Ag 2-Komponenten-Haarbehandlungsmittel und Verfahren zur gleichzeitigen Reinigung und Festigung der Haare
EP1243322A1 (fr) * 2001-03-22 2002-09-25 Primacare S.L., c/o Cognis Iberica S.L. Microcapsules (X)
US20030104020A1 (en) * 2001-11-09 2003-06-05 Davison Gordon Robert Chitosan compositions
DE10208550A1 (de) * 2002-02-27 2003-09-04 Cognis Deutschland Gmbh Transparente kosmetische Zubereitungen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10157543A1 (de) * 2001-11-23 2003-06-12 Beiersdorf Ag Emulsionsgetränkte Tücher
DE10355712A1 (de) * 2003-11-26 2005-06-16 Beiersdorf Ag Kosmetische Formulierungen auf Fettsäurebasis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19701417C1 (de) * 1997-01-17 1998-04-09 Wella Ag 2-Komponenten-Haarbehandlungsmittel und Verfahren zur gleichzeitigen Reinigung und Festigung der Haare
EP1243322A1 (fr) * 2001-03-22 2002-09-25 Primacare S.L., c/o Cognis Iberica S.L. Microcapsules (X)
US20030104020A1 (en) * 2001-11-09 2003-06-05 Davison Gordon Robert Chitosan compositions
DE10208550A1 (de) * 2002-02-27 2003-09-04 Cognis Deutschland Gmbh Transparente kosmetische Zubereitungen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012140536A (ja) * 2010-12-28 2012-07-26 Kao Corp 香料組成物

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