WO2007021762A3 - Methods and materials for fabricating microfluidic devices - Google Patents

Methods and materials for fabricating microfluidic devices Download PDF

Info

Publication number
WO2007021762A3
WO2007021762A3 PCT/US2006/031067 US2006031067W WO2007021762A3 WO 2007021762 A3 WO2007021762 A3 WO 2007021762A3 US 2006031067 W US2006031067 W US 2006031067W WO 2007021762 A3 WO2007021762 A3 WO 2007021762A3
Authority
WO
WIPO (PCT)
Prior art keywords
materials
methods
microfluidic devices
fabricating microfluidic
functional groups
Prior art date
Application number
PCT/US2006/031067
Other languages
French (fr)
Other versions
WO2007021762A2 (en
Inventor
Joseph M Desimone
Jason P Rolland
Ginger M Denison Rothrock
Paul Resnick
Original Assignee
Univ North Carolina
Joseph M Desimone
Jason P Rolland
Ginger M Denison Rothrock
Paul Resnick
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina, Joseph M Desimone, Jason P Rolland, Ginger M Denison Rothrock, Paul Resnick filed Critical Univ North Carolina
Priority to US12/063,284 priority Critical patent/US8158728B2/en
Priority to EP06801056A priority patent/EP1922364A4/en
Publication of WO2007021762A2 publication Critical patent/WO2007021762A2/en
Publication of WO2007021762A3 publication Critical patent/WO2007021762A3/en
Priority to US13/438,431 priority patent/US8444899B2/en
Priority to US13/859,323 priority patent/US20130228950A1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C59/00—Surface shaping of articles, e.g. embossing; Apparatus therefor
    • B29C59/005—Surface shaping of articles, e.g. embossing; Apparatus therefor characterised by the choice of material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C33/00—Moulds or cores; Details thereof or accessories therefor
    • B29C33/38—Moulds or cores; Details thereof or accessories therefor characterised by the material or the manufacturing process
    • B29C33/3842—Manufacturing moulds, e.g. shaping the mould surface by machining
    • B29C33/3857—Manufacturing moulds, e.g. shaping the mould surface by machining by making impressions of one or more parts of models, e.g. shaped articles and including possible subsequent assembly of the parts
    • B29C33/3878—Manufacturing moulds, e.g. shaping the mould surface by machining by making impressions of one or more parts of models, e.g. shaped articles and including possible subsequent assembly of the parts used as masters for making successive impressions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C33/00—Moulds or cores; Details thereof or accessories therefor
    • B29C33/38—Moulds or cores; Details thereof or accessories therefor characterised by the material or the manufacturing process
    • B29C33/40—Plastics, e.g. foam or rubber
    • B29C33/405—Elastomers, e.g. rubber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/48—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/54—Joining several hollow-preforms, e.g. half-shells, to form hollow articles, e.g. for making balls, containers; Joining several hollow-preforms, e.g. half-cylinders, to form tubular articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/54—Joining several hollow-preforms, e.g. half-shells, to form hollow articles, e.g. for making balls, containers; Joining several hollow-preforms, e.g. half-cylinders, to form tubular articles
    • B29C66/543—Joining several hollow-preforms, e.g. half-shells, to form hollow articles, e.g. for making balls, containers; Joining several hollow-preforms, e.g. half-cylinders, to form tubular articles joining more than two hollow-preforms to form said hollow articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
    • B29C66/71—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the composition of the plastics material of the parts to be joined
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
    • B29C66/72—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the structure of the material of the parts to be joined
    • B29C66/723—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the structure of the material of the parts to be joined being multi-layered
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
    • B29C66/72—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the structure of the material of the parts to be joined
    • B29C66/727—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the structure of the material of the parts to be joined being porous, e.g. foam
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/90—Measuring or controlling the joining process
    • B29C66/91—Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux
    • B29C66/914—Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux by controlling or regulating the temperature, the heat or the thermal flux
    • B29C66/9141—Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux by controlling or regulating the temperature, the heat or the thermal flux by controlling or regulating the temperature
    • B29C66/91431—Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux by controlling or regulating the temperature, the heat or the thermal flux by controlling or regulating the temperature the temperature being kept constant over time
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/90—Measuring or controlling the joining process
    • B29C66/91—Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux
    • B29C66/919—Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux characterised by specific temperature, heat or thermal flux values or ranges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/90—Measuring or controlling the joining process
    • B29C66/94—Measuring or controlling the joining process by measuring or controlling the time
    • B29C66/949—Measuring or controlling the joining process by measuring or controlling the time characterised by specific time values or ranges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/90—Measuring or controlling the joining process
    • B29C66/95—Measuring or controlling the joining process by measuring or controlling specific variables not covered by groups B29C66/91 - B29C66/94
    • B29C66/953—Measuring or controlling the joining process by measuring or controlling specific variables not covered by groups B29C66/91 - B29C66/94 by measuring or controlling the humidity
    • B29C66/9534—Measuring or controlling the joining process by measuring or controlling specific variables not covered by groups B29C66/91 - B29C66/94 by measuring or controlling the humidity of the atmosphere, i.e. taking the ambient humidity into account
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C99/00—Subject matter not provided for in other groups of this subclass
    • B81C99/0075—Manufacture of substrate-free structures
    • B81C99/0085—Manufacture of substrate-free structures using moulds and master templates, e.g. for hot-embossing
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/50—Polyethers having heteroatoms other than oxygen
    • C08G18/5003—Polyethers having heteroatoms other than oxygen having halogens
    • C08G18/5015—Polyethers having heteroatoms other than oxygen having halogens having fluorine atoms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/81—Unsaturated isocyanates or isothiocyanates
    • C08G18/8141—Unsaturated isocyanates or isothiocyanates masked
    • C08G18/815—Polyisocyanates or polyisothiocyanates masked with unsaturated compounds having active hydrogen
    • C08G18/8158—Polyisocyanates or polyisothiocyanates masked with unsaturated compounds having active hydrogen with unsaturated compounds having only one group containing active hydrogen
    • C08G18/8175—Polyisocyanates or polyisothiocyanates masked with unsaturated compounds having active hydrogen with unsaturated compounds having only one group containing active hydrogen with esters of acrylic or alkylacrylic acid having only one group containing active hydrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G59/00—Polycondensates containing more than one epoxy group per molecule; Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups
    • C08G59/18—Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing
    • C08G59/20—Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing characterised by the epoxy compounds used
    • C08G59/22—Di-epoxy compounds
    • C08G59/30—Di-epoxy compounds containing atoms other than carbon, hydrogen, oxygen and nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/002—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from unsaturated compounds
    • C08G65/005—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from unsaturated compounds containing halogens
    • C08G65/007—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from unsaturated compounds containing halogens containing fluorine
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L75/00—Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
    • C08L75/04—Polyurethanes
    • C08L75/14—Polyurethanes having carbon-to-carbon unsaturated bonds
    • C08L75/16—Polyurethanes having carbon-to-carbon unsaturated bonds having terminal carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D171/00—Coating compositions based on polyethers obtained by reactions forming an ether link in the main chain; Coating compositions based on derivatives of such polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/48—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding
    • B29C65/4805—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding characterised by the type of adhesives
    • B29C65/483—Reactive adhesives, e.g. chemically curing adhesives
    • B29C65/4835—Heat curing adhesives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/48—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding
    • B29C65/4805—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding characterised by the type of adhesives
    • B29C65/483—Reactive adhesives, e.g. chemically curing adhesives
    • B29C65/4845—Radiation curing adhesives, e.g. UV light curing adhesives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/48—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding
    • B29C65/4805—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding characterised by the type of adhesives
    • B29C65/483—Reactive adhesives, e.g. chemically curing adhesives
    • B29C65/485—Multi-component adhesives, i.e. chemically curing as a result of the mixing of said multi-components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/48—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding
    • B29C65/52—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding characterised by the way of applying the adhesive
    • B29C65/521—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding characterised by the way of applying the adhesive by spin coating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2883/00—Use of polymers having silicon, with or without sulfur, nitrogen, oxygen, or carbon only, in the main chain, as mould material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/712—Containers; Packaging elements or accessories, Packages
    • B29L2031/7172—Fuel tanks, jerry cans
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/756—Microarticles, nanoarticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00—Specific applications of microelectromechanical systems
    • B81B2201/05—Microfluidics
    • B81B2201/051—Micromixers, microreactors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
    • Y10T137/2224—Structure of body of device

Abstract

Materials and methods are provided for fabricating microfluidic devices. The materials include low surface energy fluoropolymer compositions having multiple cure functional groups. The materials can include multiple photocurable and/or thermal-curable functional groups such that laminate devices can be fabricated. The materials also substantially do not swell in the presence of hydrocarbon solvents.
PCT/US2006/031067 2004-02-13 2006-08-09 Methods and materials for fabricating microfluidic devices WO2007021762A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US12/063,284 US8158728B2 (en) 2004-02-13 2006-08-09 Methods and materials for fabricating microfluidic devices
EP06801056A EP1922364A4 (en) 2005-08-09 2006-08-09 Methods and materials for fabricating microfluidic devices
US13/438,431 US8444899B2 (en) 2004-02-13 2012-04-03 Methods and materials for fabricating microfluidic devices
US13/859,323 US20130228950A1 (en) 2005-08-09 2013-04-09 Methods and materials for fabricating microfluidic devices

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US70678605P 2005-08-09 2005-08-09
US60/706,786 2005-08-09
US73272705P 2005-11-02 2005-11-02
US60/732,727 2005-11-02
US79931706P 2006-05-10 2006-05-10
US60/799,317 2006-05-10

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/004421 Continuation-In-Part WO2005084191A2 (en) 2004-02-13 2005-02-14 Functional materials and novel methods for the fabrication of microfluidic devices

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US12/063,284 A-371-Of-International US8158728B2 (en) 2004-02-13 2006-08-09 Methods and materials for fabricating microfluidic devices
US13/438,431 Division US8444899B2 (en) 2004-02-13 2012-04-03 Methods and materials for fabricating microfluidic devices

Publications (2)

Publication Number Publication Date
WO2007021762A2 WO2007021762A2 (en) 2007-02-22
WO2007021762A3 true WO2007021762A3 (en) 2007-08-30

Family

ID=37758124

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/031067 WO2007021762A2 (en) 2004-02-13 2006-08-09 Methods and materials for fabricating microfluidic devices

Country Status (3)

Country Link
US (3) US8158728B2 (en)
EP (2) EP1922364A4 (en)
WO (1) WO2007021762A2 (en)

Families Citing this family (199)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11243494B2 (en) 2002-07-31 2022-02-08 Abs Global, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
US9040090B2 (en) 2003-12-19 2015-05-26 The University Of North Carolina At Chapel Hill Isolated and fixed micro and nano structures and methods thereof
US20070266801A1 (en) * 2005-12-16 2007-11-22 Alireza Khademhosseini Reversible Sealing of Microfluidic Arrays
US8944804B2 (en) * 2006-01-04 2015-02-03 Liquidia Technologies, Inc. Nanostructured surfaces for biomedical/biomaterial applications and processes thereof
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8808726B2 (en) 2006-09-15 2014-08-19 Boston Scientific Scimed. Inc. Bioerodible endoprostheses and methods of making the same
GB2443322B (en) * 2006-10-28 2010-09-08 P2I Ltd Plasma coated microfabricated device or component thereof
GB0621520D0 (en) 2006-10-28 2006-12-06 P2I Ltd Novel products
US8128393B2 (en) 2006-12-04 2012-03-06 Liquidia Technologies, Inc. Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom
US20110168631A1 (en) * 2006-12-15 2011-07-14 General Electric Company Methods and apparatuses for water filtration using polyarylether membranes
WO2008083190A2 (en) 2006-12-28 2008-07-10 Boston Scientific Limited Bioerodible endoprostheses and methods of making same
WO2009049299A1 (en) 2007-10-12 2009-04-16 Liquidia Technologies, Inc. System and method for producing particles and patterned films
US20090191409A1 (en) * 2008-01-25 2009-07-30 Steve Simon Combined Wetting/Non-Wetting Element For Low and High Surface Tension Liquids
US9893337B2 (en) 2008-02-13 2018-02-13 Seeo, Inc. Multi-phase electrolyte lithium batteries
US9480461B2 (en) * 2008-03-10 2016-11-01 Volatile Analysis Corporation Methods for extracting chemicals from nasal cavities and breath
US8034396B2 (en) 2008-04-01 2011-10-11 Tyco Healthcare Group Lp Bioadhesive composition formed using click chemistry
KR100919400B1 (en) * 2008-04-07 2009-09-29 삼성전자주식회사 Microfluidic device and method for fabricating the same
WO2009129430A2 (en) * 2008-04-18 2009-10-22 University Of Massachusetts Lowell Methods for forming metal-polymer hybrid tooling for forming parts having micro features
EP2303186A1 (en) * 2008-06-25 2011-04-06 Boston Scientific Scimed, Inc. Medical devices having superhydrophobic surfaces
US8241547B2 (en) * 2008-10-02 2012-08-14 California Institute Of Technology Lithographically defined adhesion microstructures
US20100098847A1 (en) * 2008-10-21 2010-04-22 Molecular Imprints, Inc. Drop Deposition Materials for Imprint Lithography
JP5340760B2 (en) * 2009-02-12 2013-11-13 倉敷紡績株式会社 Fluid control method and fluid control apparatus
WO2010095052A2 (en) 2009-02-21 2010-08-26 Sofradim Production Compounds and medical devices activated with solvophobic linkers
AU2010215203B2 (en) 2009-02-21 2015-07-16 Covidien Lp Medical devices with an activated coating
US8877170B2 (en) 2009-02-21 2014-11-04 Sofradim Production Medical device with inflammatory response-reducing coating
WO2010095047A2 (en) 2009-02-21 2010-08-26 Sofradim Production Apparatus and method of reacting polymers passing through metal ion chelated resin matrix to produce injectable medical devices
EP2398524B1 (en) 2009-02-21 2017-07-12 Covidien LP Medical devices having activated surfaces
US8535477B2 (en) 2009-02-21 2013-09-17 Sofradim Production Medical devices incorporating functional adhesives
US8512728B2 (en) 2009-02-21 2013-08-20 Sofradim Production Method of forming a medical device on biological tissue
WO2010095045A1 (en) 2009-02-21 2010-08-26 Sofradim Production Amphiphilic compounds and self-assembling compositions made therefrom
US8968733B2 (en) 2009-02-21 2015-03-03 Sofradim Production Functionalized surgical adhesives
AU2010215196B2 (en) 2009-02-21 2015-04-16 Covidien Lp Crosslinked fibers and method of making same by extrusion
CA2753188A1 (en) 2009-02-21 2010-08-26 Tyco Healthcare Group Lp Medical devices having activated surfaces
US9523159B2 (en) 2009-02-21 2016-12-20 Covidien Lp Crosslinked fibers and method of making same using UV radiation
US8663689B2 (en) 2009-02-21 2014-03-04 Sofradim Production Functionalized adhesive medical gel
CA2753166A1 (en) 2009-02-21 2010-08-26 Sofradim Production Apparatus and method of reacting polymers by exposure to uv radiation to produce injectable medical devices
US8512935B2 (en) * 2009-05-08 2013-08-20 Hewlett-Packard Development Company, L.P. Functionalized perfluoropolyether material as a hydrophobic coating
NL2005263A (en) * 2009-09-29 2011-03-30 Asml Netherlands Bv Imprint lithography.
US8283569B2 (en) * 2010-01-22 2012-10-09 The Regents Of The University Of Michigan Electrode array and method of fabrication
WO2011119573A1 (en) * 2010-03-23 2011-09-29 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US8795331B2 (en) 2010-03-25 2014-08-05 Covidien Lp Medical devices incorporating functional adhesives
US9272074B2 (en) 2010-03-25 2016-03-01 Sofradim Production Surgical fasteners and methods for sealing wounds
WO2012006147A1 (en) 2010-06-29 2012-01-12 Tyco Healthcare Group Lp Microwave-powered reactor and method for in situ forming implants
AU2011273102A1 (en) 2010-07-01 2013-01-31 Sofradim Production Medical device with predefined activated cellular integration
US9168679B2 (en) * 2010-07-16 2015-10-27 Northwestern University Programmable soft lithography: solvent-assisted nanoscale embossing
WO2012014080A2 (en) 2010-07-27 2012-02-02 Sofradim Production Polymeric fibers having tissue reactive members
US10908066B2 (en) 2010-11-16 2021-02-02 1087 Systems, Inc. Use of vibrational spectroscopy for microfluidic liquid measurement
US9012127B2 (en) 2010-11-29 2015-04-21 The Regents Of The University Of Colorado, A Body Corporate Thermoreversible network scaffolds and methods of preparing same
JP5616309B2 (en) * 2010-12-01 2014-10-29 アークレイ株式会社 Device and manufacturing method thereof
DE102011009923A1 (en) * 2011-01-31 2012-08-02 Mann + Hummel Gmbh Ion exchanger for the treatment of a liquid fluid
DE102011102266B4 (en) * 2011-05-23 2013-04-11 Epcos Ag Arrangement with a MEMS component with a PFPE layer and method for the production
ITMI20110995A1 (en) * 2011-05-31 2012-12-01 Ione METHOD FOR THE PRODUCTION OF MONOLITHIC THREE-DIMENSIONAL MICROFLUID DEVICES
US9541480B2 (en) 2011-06-29 2017-01-10 Academia Sinica Capture, purification, and release of biological substances using a surface coating
US20130142835A1 (en) * 2011-07-06 2013-06-06 Alexander M. Seifalian Synthetic scaffolds and organ and tissue transplantation
JP6082237B2 (en) * 2011-12-09 2017-02-15 株式会社トクヤマ Manufacturing method of silicon substrate having texture structure
EP2626133A1 (en) * 2012-02-10 2013-08-14 Chemtrix B.V. Micro-fluidic system
US9802349B2 (en) 2012-03-02 2017-10-31 Taiwan Semiconductor Manufacturing Company, Ltd. Wafer level transfer molding and apparatus for performing the same
US8951037B2 (en) 2012-03-02 2015-02-10 Taiwan Semiconductor Manufacturing Company, Ltd. Wafer-level underfill and over-molding
EP2839260B1 (en) 2012-04-20 2018-07-18 Talis Biomedical Corporation Fluidic devices and systems for sample preparation or autonomous analysis
WO2013159116A1 (en) 2012-04-20 2013-10-24 University Of Chicago Fluidic devices for biospecimen preservation
JP5827180B2 (en) * 2012-06-18 2015-12-02 富士フイルム株式会社 Imprint curable composition and substrate adhesion composition, and semiconductor device using the same
WO2013191908A1 (en) 2012-06-20 2013-12-27 The University Of North Carolina At Chapel Hill Integrated sample processing for electrospray ionization devices
SG10201610755RA (en) * 2012-06-29 2017-02-27 Johnson & Johnson Vision Care Multiple state electroactive ophthalmic device
SG11201500017YA (en) * 2012-07-09 2015-02-27 Sony Corp Microchip and method for producing manufacturing the same
US9353313B2 (en) 2012-08-09 2016-05-31 Auburn University Microdevices and methods of manufacture
JP6077792B2 (en) * 2012-08-28 2017-02-08 株式会社ブリヂストン A member having at least a cured layer formed by curing a curable resin composition
US9623605B2 (en) * 2012-09-12 2017-04-18 International Business Machines Corporation Thermally cross-linkable photo-hydrolyzable inkjet printable polymers for microfluidic channels
DE102012217487A1 (en) * 2012-09-26 2014-04-17 Agilent Technologies, Inc. - A Delaware Corporation - Fluid interface between fluid lines of different cross sections
US9748604B2 (en) 2012-10-19 2017-08-29 The University Of North Carolina At Chapel Hill Ion conducting polymers and polymer blends for alkali metal ion batteries
US9376311B2 (en) * 2012-12-17 2016-06-28 University Of Maryland, College Park Method for fabricating thermoplastic fluidic devices by orogenic growth and fluidic devices manufactured thereby
US10189983B2 (en) 2012-12-28 2019-01-29 Toyo Gosei Co., Ltd. Curable resin composition, resin mold for imprinting, method for photo imprinting, method for manufacturing semiconductor integrated circuit, and method for manufacturing fine optical element
WO2014113679A1 (en) * 2013-01-18 2014-07-24 The University Of North Carolina At Chapel Hill High-throughput manufacturing of microneedles
US9308616B2 (en) 2013-01-21 2016-04-12 Innovative Finishes LLC Refurbished component, electronic device including the same, and method of refurbishing a component of an electronic device
EP3358405A1 (en) 2013-02-12 2018-08-08 Carbon, Inc. Method and apparatus for three-dimensional fabrication
WO2014126837A2 (en) 2013-02-12 2014-08-21 Eipi Systems, Inc. Continuous liquid interphase printing
CN105026449B (en) 2013-03-04 2021-05-04 东洋合成工业株式会社 Composition, resin mold, optical imprint method, method for manufacturing optical element, and method for manufacturing electronic element
US9718056B2 (en) 2013-03-15 2017-08-01 Syracuse University Microfluidics polymerase chain reaction and high resolution melt detection
WO2014146937A2 (en) 2013-03-22 2014-09-25 Vlyte Innovations Limited An electrophoretic device having a transparent light state
WO2014204547A2 (en) 2013-04-01 2014-12-24 The University Of North Carolina At Chapel Hill Ion conducting fluoropolymer carbonates for alkali metal ion batteries
US20160060470A1 (en) * 2013-05-01 2016-03-03 Innovative Finishes LLC Method of refurbishing an electronic device component
US9775928B2 (en) 2013-06-18 2017-10-03 Covidien Lp Adhesive barbed filament
GB201311679D0 (en) 2013-06-28 2013-08-14 Ibm Microfluidic chip with dielectrophoretic electrodes extending in hydrophilic flow path
US8961904B2 (en) 2013-07-16 2015-02-24 Premium Genetics (Uk) Ltd. Microfluidic chip
DE102013012731A1 (en) * 2013-08-01 2015-02-05 Krohne Messtechnik Gmbh Process for the preparation of a gas converter and corresponding gas converter
US10005248B2 (en) 2013-09-20 2018-06-26 The Regents Of The University Of California Method and kit for forming plastic lenses from molds formed on surface with varied wettability
DE102013017317A1 (en) * 2013-10-18 2015-04-23 Endress + Hauser Flowtec Ag Measuring arrangement with a carrier element and a sensor
US10324353B2 (en) 2013-10-22 2019-06-18 Vlyte Innovations Limited Wide operating temperature range electrophoretic device
US9045582B2 (en) * 2013-10-29 2015-06-02 Uop Llc Cross-linked rubbery polyurethane-ether membranes for separations
US11796449B2 (en) 2013-10-30 2023-10-24 Abs Global, Inc. Microfluidic system and method with focused energy apparatus
KR102208014B1 (en) * 2013-11-07 2021-01-26 에이지씨 가부시키가이샤 Mold release film and semiconductor package manufacturing method
TW201520019A (en) * 2013-11-20 2015-06-01 Univ Nat Taiwan Science Tech Fabrication method for three dimensional micro-structure of polymers
CA2932015A1 (en) 2013-12-06 2015-06-11 Envisia Therapeutics Inc. Intracameral implant for treatment of an ocular condition
US9969964B2 (en) * 2013-12-23 2018-05-15 Purdue Research Foundation Disease-on-a-chip
WO2015103331A1 (en) * 2013-12-31 2015-07-09 Canon U.S. Life Sciences, Inc. Methods and systems for continuous flow cell lysis in a microfluidic device
US10232605B2 (en) 2014-03-21 2019-03-19 Carbon, Inc. Method for three-dimensional fabrication with gas injection through carrier
EP3126814B1 (en) 2014-04-01 2019-06-12 Academia Sinica Methods and systems for cancer diagnosis and prognosis
US10464307B2 (en) 2014-05-20 2019-11-05 The Regents Of The University Of California Layerless bioprinting via dynamic optical projection and uses thereof
US10620200B2 (en) * 2014-05-29 2020-04-14 The Board Of Regents Of The University Of Texas System Methods and compositions for hybrid microfluidic devices integrated with nano-biosensors
MX2016017099A (en) 2014-06-20 2017-08-07 Carbon Inc Three-dimensional printing with reciprocal feeding of polymerizable liquid.
US10569465B2 (en) 2014-06-20 2020-02-25 Carbon, Inc. Three-dimensional printing using tiled light engines
US10661501B2 (en) 2014-06-20 2020-05-26 Carbon, Inc. Three-dimensional printing method using increased light intensity and apparatus therefor
JP6720092B2 (en) 2014-06-23 2020-07-08 カーボン，インコーポレイテッド Method for manufacturing polyurethane three-dimensional object from materials having various curing mechanisms
WO2016025579A1 (en) 2014-08-12 2016-02-18 Carbon3D, Inc. Three-dimensional printing with build plates having a smooth or patterned surface and related methods
US10112198B2 (en) 2014-08-26 2018-10-30 Academia Sinica Collector architecture layout design
CN107074530A (en) * 2014-08-29 2017-08-18 生物辐射实验室股份有限公司 For the epoxides molding of microfluid and micro- milling
WO2016040850A1 (en) * 2014-09-11 2016-03-17 Oregon State University Microfluidic device for removal of constituents from blood
US9575226B2 (en) * 2014-09-22 2017-02-21 The Chinese University Of Hong Kong Positive microcontact printing
US20160124205A1 (en) * 2014-10-27 2016-05-05 Yale University Simple, Fast and Plasma-Free Method of Fabricating PDMS Microstructures on Glass by Pop Slide Pattering
US9896592B2 (en) 2014-11-21 2018-02-20 Vernay Laboratories, Inc. Temporary elastomeric functional barrier membrane and method of manufacture
EP3240671B1 (en) 2014-12-31 2020-12-16 Carbon, Inc. Three-dimensional printing of objects with breathing orifices
US20160193786A1 (en) 2015-01-06 2016-07-07 Carbon3D, Inc. Three-dimensional printing with build plates having a rough or patterned surface and related methods
WO2016112090A1 (en) 2015-01-07 2016-07-14 Carbon3D, Inc. Microfluidic devices and methods of making the same
US20160200052A1 (en) 2015-01-13 2016-07-14 Carbon3D, Inc. Three-dimensional printing with build plates having surface topologies for increasing permeability and related methods
EP3250368A1 (en) 2015-01-30 2017-12-06 Carbon, Inc. Build plates for continuous liquid interface printing having permeable sheets and related methods, systems and devices
WO2016123499A1 (en) 2015-01-30 2016-08-04 Carbon3D, Inc. Build plates for continuous liquid interface printing having permeable base and adhesive for increasing permeability and related methods, systems and devices
US10308587B2 (en) 2015-02-03 2019-06-04 Blue Current, Inc. Functionalized fluoropolymers and electrolyte compositions
WO2016126779A1 (en) 2015-02-05 2016-08-11 Carbon3D, Inc. Method of additive manufacturing by fabrication through multiple zones
SG11201706777QA (en) 2015-02-19 2017-09-28 Premium Genetics (Uk) Ltd Scanning infrared measurement system
WO2016140886A1 (en) 2015-03-05 2016-09-09 Carbon3D, Inc. Fabrication of three dimensional objects with multiple operating modes
US20180029292A1 (en) 2015-03-05 2018-02-01 Carbon, Inc. Continuous liquid interface production with sequential patterned exposure
WO2016140888A1 (en) 2015-03-05 2016-09-09 Carbon3D, Inc. Fabrication of three dimensional objects with variable slice thickness
WO2016145050A1 (en) 2015-03-10 2016-09-15 Carbon3D, Inc. Microfluidic devices having flexible features and methods of making the same
WO2016149097A1 (en) 2015-03-13 2016-09-22 Carbon3D, Inc. Three-dimensional printing with reduced pressure build plate unit
WO2016149151A1 (en) 2015-03-13 2016-09-22 Carbon3D, Inc. Three-dimensional printing with concurrent delivery of different polymerizable liquids
WO2016149104A1 (en) 2015-03-13 2016-09-22 Carbon3D, Inc. Three-dimensional printing with flexible build plates
GB2554218A (en) * 2015-03-17 2018-03-28 Harvard College Automated membrane fabrication system
DK3274092T3 (en) 2015-03-27 2020-02-03 Univ Wageningen MICROFLUIDIC DEVICE
WO2016161465A1 (en) * 2015-04-03 2016-10-06 Seeo, Inc. Fluorinated alkali ion electrolytes with urethane groups
US9923245B2 (en) 2015-04-03 2018-03-20 Seeo, Inc. Fluorinated alkali ion electrolytes with urethane groups
WO2016164505A1 (en) 2015-04-07 2016-10-13 Seeo, Inc. Fluorinated alkali ion electrolytes with cyclic carbonate groups
US20160301107A1 (en) * 2015-04-07 2016-10-13 Blue Current, Inc. Functionalized perfluoroalkanes and electrolyte compositions
EP3085661B1 (en) * 2015-04-21 2017-12-27 JSR Corporation Method of producing microfluidic device
WO2016182797A1 (en) 2015-05-12 2016-11-17 Seeo, Inc. Copolymers of peo and fluorinated polymers as electrolytes for lithium batteries
WO2016196365A1 (en) 2015-05-29 2016-12-08 Envisia Therapeutics, Inc. Implant for treatment of an ocular condition
WO2016200559A1 (en) 2015-06-09 2016-12-15 Seeo, Inc. Peo-based graft copolymers with pendant fluorinated groups for use as electrolytes
US20210228408A1 (en) 2015-07-23 2021-07-29 Allergan, Inc. Glaucoma Treatment Via Intracameral Ocular Implants
UY36851A (en) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd COMPOUNDS FOR USE IN ANTIBACTERIAL APPLICATIONS
ES2908479T3 (en) 2015-08-26 2022-04-29 Achillion Pharmaceuticals Inc Compounds for the treatment of immune and inflammatory disorders
AR106018A1 (en) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc ARYL, HETEROARYL AND HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS
JP6889155B2 (en) 2015-09-25 2021-06-18 カーボン，インコーポレイテッド Build plate assembly for continuous liquid-phase printing with a writing panel, and related methods, systems and devices
US10384439B2 (en) 2015-11-06 2019-08-20 Stratasys, Inc. Continuous liquid interface production system with viscosity pump
CA3004492A1 (en) 2015-11-18 2017-05-26 Glaxosmithkline Intellectual Property (No.2) Limited Pharmaceutical compositions of ribavirin
WO2017112483A2 (en) 2015-12-22 2017-06-29 Carbon, Inc. Accelerants for additive manufacturing with dual cure resins
WO2017112521A1 (en) 2015-12-22 2017-06-29 Carbon, Inc. Production of flexible products by additive manufacturing with dual cure resins
US10639844B2 (en) * 2015-12-22 2020-05-05 Carbon, Inc. Fabrication of compound products from multiple intermediates by additive manufacturing with dual cure resins
US10350823B2 (en) 2015-12-22 2019-07-16 Carbon, Inc. Dual precursor resin systems for additive manufacturing with dual cure resins
WO2017112571A1 (en) 2015-12-22 2017-06-29 Carbon, Inc. Dual cure additive manufacturing of rigid intermediates that generate semi-rigid, flexible, or elastic final products
US11268607B1 (en) 2016-02-17 2022-03-08 Helix Linear Technologies Lead screw nuts having threads formed from different materials
WO2017142950A1 (en) * 2016-02-17 2017-08-24 President And Fellows Of Harvard College Microfluidic device for shear flow testing and methods for using the same
BE1024210B1 (en) 2016-03-07 2017-12-18 Glaxosmithkline Biologicals Sa PARTICLES FOR DRUG DELIVERY
US10107726B2 (en) 2016-03-16 2018-10-23 Cellmax, Ltd. Collection of suspended cells using a transferable membrane
WO2017181186A1 (en) * 2016-04-15 2017-10-19 Vortex Biosciences, Inc. Microfluidic chips and cartridges and systems utilizing microfluidic chips and cartridges
CA3023257A1 (en) 2016-05-05 2017-11-09 Liquidia Technologies, Inc. Dry powder treprostinil for the treatment of pulmonary hypertension
WO2017196308A1 (en) 2016-05-10 2017-11-16 Seeo, Inc. Fluorinated electrolytes with nitrile groups
RU2018145364A (en) 2016-06-27 2020-07-28 Ачиллион Фармасьютикалс, Инк. QUINAZOLINE AND INDOLE COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS
EP3423256B1 (en) 2016-07-01 2022-02-23 Carbon, Inc. Three-dimensional printing method and apparatus for reducing bubbles by de-gassing through build plate
WO2018027009A1 (en) * 2016-08-05 2018-02-08 Microoptx Inc. Polymeric devices and methods of making
CN109689215B (en) * 2016-09-12 2021-12-28 Abs全球公司 Method and system for hydrophobic coating of microfluidic chips
US10725373B1 (en) * 2016-10-21 2020-07-28 Iowa State University Research Foundation, Inc. Nano-patterning methods including: (1) patterning of nanophotonic structures at optical fiber tip for refractive index sensing and (2) plasmonic crystal incorporating graphene oxide gas sensor for detection of volatile organic compounds
US11226278B2 (en) 2016-11-08 2022-01-18 Kennesaw State University Research And Service Foundation, Inc. Leukocyte quantitation microfluidic method and device
EP3541391A4 (en) 2016-11-17 2020-06-17 The University of North Carolina at Chapel Hill Alkyl pyrrolopyrimidine analogs and methods of making and using same
WO2018118978A1 (en) * 2016-12-20 2018-06-28 Bio-Rad Laboratories, Inc. Uv graft on microfluidic devices
JP6968833B2 (en) 2017-01-26 2021-11-17 昭和電工株式会社 Fluorine-containing ether compounds, lubricants for magnetic recording media and magnetic recording media
USD1016599S1 (en) 2017-02-17 2024-03-05 Helix Linear Technologies Nut
KR101793864B1 (en) * 2017-03-08 2017-11-06 인하대학교 산학협력단 Superhydrophobic surface treatment based on anthracene-perfluoropolyether and method for treating the surface of superhydrophobic of PET fiber using the same
JP7174715B2 (en) * 2017-06-08 2022-11-17 インテグラ バイオサイエンシーズ アーゲー Sample container and reagent container with vacuum protection arrangement
US10597289B1 (en) * 2017-07-17 2020-03-24 Adam Woolley 3D printer, resin, and interconnect
WO2019110591A1 (en) * 2017-12-06 2019-06-13 Samplix Aps A microfluidic device and a method for provision of emulsion droplets
MX2020009148A (en) * 2018-03-02 2021-01-20 Quantumcyte Inc Methods, compositions, and devices for isolation and expression analysis of regions of interest from a tissue.
US11867320B2 (en) 2018-03-02 2024-01-09 National Research Council Of Canada Polymeric microfluidic valve
US20210022651A1 (en) * 2018-03-23 2021-01-28 The Regents Of The University Of California Three-dimensional microfluidic actuation and sensing wearable device for in-situ biofluid processing and analysis
CN110433876B (en) * 2018-05-03 2022-05-17 香港科技大学 Microfluidic device, manufacturing method thereof, mask and method for filtering suspended particles
EP3796998A1 (en) 2018-05-23 2021-03-31 ABS Global, Inc. Systems and methods for particle focusing in microchannels
WO2020035805A2 (en) * 2018-08-14 2020-02-20 Texas Tech University System Methods and systems for making tilted and curved structures with high aspect ratios
EP3841086A4 (en) 2018-08-20 2022-07-27 Achillion Pharmaceuticals, Inc. Pharmaceutical compounds for the treatment of complement factor d medical disorders
US11767483B2 (en) 2018-09-12 2023-09-26 Resonac Corporation Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium
CN113365617A (en) 2018-10-16 2021-09-07 乔治亚州立大学研究基金会股份有限公司 Carbon monoxide prodrugs for the treatment of medical conditions
US11820953B2 (en) 2019-03-12 2023-11-21 Resonac Corporation Fluorine-containing ether compound, lubricant for magnetic recording medium and magnetic recording medium
DE102019107090A1 (en) * 2019-03-20 2020-09-24 Joanneum Research Forschungsgesellschaft Mbh Microstructure with thermoplastic embossing lacquer layer and manufacturing process
WO2020215011A1 (en) 2019-04-18 2020-10-22 Abs Global, Inc. System and process for continuous addition of cryoprotectant
CN110054756A (en) * 2019-04-26 2019-07-26 同济大学 The polyurethane resin and preparation method thereof of organic-silicon-modified fluorine-containing carbon branch
CN110183598B (en) * 2019-06-28 2020-03-10 苏州大学 Light polymerization method of block copolymer of main chain type semi-fluorine alternative copolymer
CN114341094B (en) 2019-09-18 2024-01-12 株式会社力森诺科 Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium
GB201913529D0 (en) * 2019-09-19 2019-11-06 Tanriverdi Ugur Method And Apparatus
CN114845989A (en) 2019-12-26 2022-08-02 昭和电工株式会社 Fluorinated ether compound, lubricant for magnetic recording medium, and magnetic recording medium
US11628439B2 (en) 2020-01-13 2023-04-18 Abs Global, Inc. Single-sheath microfluidic chip
EP3888927B1 (en) * 2020-03-31 2023-09-13 Canon Production Printing Holding B.V. Method for applying an image onto a recording medium
DE102020114621A1 (en) * 2020-06-02 2021-12-02 Joanneum Research Forschungsgesellschaft Mbh Component with microfluidic structures, manufacturing process and use
US11833742B2 (en) 2020-06-26 2023-12-05 The Regents Of The University Of California High-fidelity 3D printing using flashing photopolymerization
CN111701629B (en) * 2020-07-03 2021-04-02 清华大学 Super-hydrophobic micro-pit array chip and preparation method and device thereof
US11813608B2 (en) 2020-09-22 2023-11-14 Oregon State University Fiber substrate-based fluidic analytical devices and methods of making and using the same
GB2603487A (en) * 2021-02-04 2022-08-10 Stewart Callum Composition
CA3212659A1 (en) * 2021-03-11 2022-09-15 President And Fellows Of Harvard College Fluorinated elastomers for brain probes and other applications
CN113527860B (en) * 2021-06-29 2022-07-19 江西岳峰集团环保新材有限公司 Preparation method of PPO composite material with high melt flowability
NL2030209B1 (en) 2021-12-21 2023-06-29 Surfix B V Process for manufacturing a microfluidic device
CN114177962A (en) * 2022-01-07 2022-03-15 中国科学院青岛生物能源与过程研究所 Method for manufacturing sandwich micro-fluidic chip
DE102022107894A1 (en) * 2022-04-01 2023-10-05 Eberhard Karls Universität Tübingen, Körperschaft des öffentlichen Rechts Method of manufacturing a reactor, reactors and assemblies
CN115433340B (en) * 2022-09-26 2023-12-22 山东安然纳米实业发展有限公司 Preparation method of photo-curing functional slurry, preparation method of functional fiber and functional fiber
WO2024074585A2 (en) 2022-10-05 2024-04-11 Mireca Medicines Gmbh MICROPARTICLE AND IMPLANT FORMULATIONS FOR cGMP ANALOG THERAPY

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5412034A (en) * 1993-10-26 1995-05-02 E. I. Du Pont De Nemours And Company Curable elastomeric blends
US5459202A (en) * 1994-06-30 1995-10-17 E. I. Du Pont De Nemours And Company Elastomer seal

Family Cites Families (215)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3810874A (en) 1969-03-10 1974-05-14 Minnesota Mining & Mfg Polymers prepared from poly(perfluoro-alkylene oxide) compounds
BE755943A (en) 1969-09-10 1971-03-09 Rhone Poulenc Sa PROCESS FOR PREPARING UNSATURATED ORGANOSILICIC COMPOUNDS
US3739015A (en) 1970-09-04 1973-06-12 Tanabe Seiyaku Co Esters of p-phenoxy and p-alkoxy cinnamic acid
BE787487A (en) 1971-08-13 1973-02-12 Ciba Geigy AGENTS FOR REGULATING PLANT GROWTH
US4353977A (en) 1981-09-02 1982-10-12 Polaroid Corporation Method for forming a photosensitive silver halide element
US4352874A (en) 1981-09-02 1982-10-05 Polaroid Corporation Method for forming a photosensitive silver halide element
US4356257A (en) 1981-09-02 1982-10-26 Polaroid Corporation Photosensitive silver halide element and method of preparing same
US4359526A (en) 1981-09-02 1982-11-16 Polaroid Corporation Method for forming a photosensitive silver halide element
US4818801A (en) 1982-01-18 1989-04-04 Minnesota Mining And Manufacturing Company Ophthalmic device comprising a polymer of a telechelic perfluoropolyether
US4512848A (en) 1984-02-06 1985-04-23 Exxon Research And Engineering Co. Procedure for fabrication of microstructures over large areas using physical replication
US4614667A (en) 1984-05-21 1986-09-30 Minnesota Mining And Manufacturing Company Composite low surface energy liner of perfluoropolyether
IT1185520B (en) 1985-02-22 1987-11-12 Montefluos Spa POLYACRYLATES AND FLUORINATED POLYACRYLAMIDS WITH A CONTROLLED RETICULATION DEGREE AND THEIR PREPARATION PROCEDURE
US4663274A (en) 1985-04-01 1987-05-05 Polaroid Corporation Method for forming a photosensitive silver halide element
NL8500992A (en) 1985-04-03 1986-11-03 Stork Screens Bv PROCESS FOR FORMING A PATTERNED PHOTOPOLYMER COATING ON A PRINTING ROLLER AND PRINTING ROLLER WITH PATTERNED PHOTOPOLYMER COATING.
US4694045A (en) 1985-12-11 1987-09-15 E. I. Du Pont De Nemours And Company Base resistant fluoroelastomers
JPS6257448A (en) * 1985-09-05 1987-03-13 Mitsubishi Petrochem Co Ltd Eluororesin composition
JPH0759669B2 (en) * 1986-10-20 1995-06-28 エヌティエヌ株式会社 Lubricating resin composition
US4830910A (en) 1987-11-18 1989-05-16 Minnesota Mining And Manufacturing Company Low adhesion compositions of perfluoropolyethers
US5175030A (en) 1989-02-10 1992-12-29 Minnesota Mining And Manufacturing Company Microstructure-bearing composite plastic articles and method of making
US5189135A (en) 1989-06-28 1993-02-23 Syremont S.P.A. Fluorinated polyurethanes with hydroxy functionality, process for preparing them and their use for the treatment of lithoidal material
US5279689A (en) 1989-06-30 1994-01-18 E. I. Du Pont De Nemours And Company Method for replicating holographic optical elements
US5770029A (en) 1996-07-30 1998-06-23 Soane Biosciences Integrated electrophoretic microdevices
US5368789A (en) 1990-09-28 1994-11-29 Canon Kabushiki Kaisha Method for forming substrate sheet for optical recording medium
JPH04288305A (en) 1991-03-15 1992-10-13 Nippon Mektron Ltd Production of peroxide-vulcanizable fluoroelastomer
DE4114598A1 (en) 1991-05-04 1992-11-05 Bayer Ag UNCROSSLINKED COPOLYMERISATES WITH REACTIVE DOUBLE BINDINGS FROM FLUOROMONERIC AND NON-CONJUGATED SERVES AND METHOD FOR THEIR PRODUCTION
DE4125201C1 (en) 1991-07-30 1992-10-01 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung Ev, 8000 Muenchen, De
JPH0580530A (en) 1991-09-24 1993-04-02 Hitachi Ltd Production of thin film pattern
US5883632A (en) 1992-05-04 1999-03-16 Hewlett-Packard Company Coordinating color produced by two devices--using a hue-controlled machine color space, or surface scaling
US5639423A (en) 1992-08-31 1997-06-17 The Regents Of The University Of Calfornia Microfabricated reactor
US5958202A (en) 1992-09-14 1999-09-28 Perseptive Biosystems, Inc. Capillary electrophoresis enzyme immunoassay
US5628930A (en) 1992-10-27 1997-05-13 Alliance Pharmaceutical Corp. Stabilization of fluorocarbon emulsions
EP0906935B1 (en) * 1992-12-10 2004-07-14 Daikin Industries, Limited Thermoplastic resin composition comprising fluoro resin and polyamide
DE69405451T2 (en) 1993-03-16 1998-03-12 Koninkl Philips Electronics Nv Method and device for producing a structured relief image from cross-linked photoresist on a flat substrate surface
US5268405A (en) 1993-03-31 1993-12-07 E. I. Du Pont De Nemours And Company Low temperature perfluoroelastomers
US5512131A (en) 1993-10-04 1996-04-30 President And Fellows Of Harvard College Formation of microstamped patterns on surfaces and derivative articles
IT1265461B1 (en) 1993-12-29 1996-11-22 Ausimont Spa FLUOROELASTOMERS INCLUDING MONOMERIC UNITS ARISING FROM A BIS-OLEPHINE
IT1269514B (en) 1994-05-18 1997-04-01 Ausimont Spa VULCANIZABLE FLUOROELASTOMERS PEROXIDE, PARTICULARLY SUITABLE FOR O-RING MANUFACTURE
IL113691A0 (en) 1994-06-10 1995-08-31 Johnson & Johnson Vision Prod Low oxygen molding of soft contact lenses
US5760100B1 (en) 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
JP3327016B2 (en) 1994-12-06 2002-09-24 ダイキン工業株式会社 Fluororubber copolymer excellent in low-temperature sealability and its curing composition
US5630902A (en) 1994-12-30 1997-05-20 Honeywell Inc. Apparatus for use in high fidelty replication of diffractive optical elements
KR19980703533A (en) 1995-04-04 1998-11-05 발덱베르너 Cell growth matrix polymer
EP1143538B1 (en) 1995-07-17 2005-09-14 Chisso Corporation Organic electroluminescent element containing a silacyclopentadiene derivative
WO1997006012A1 (en) 1995-08-04 1997-02-20 International Business Machines Corporation Stamp for a lithographic process
US6130098A (en) 1995-09-15 2000-10-10 The Regents Of The University Of Michigan Moving microdroplets
US20040137734A1 (en) 1995-11-15 2004-07-15 Princeton University Compositions and processes for nanoimprinting
US5772905A (en) 1995-11-15 1998-06-30 Regents Of The University Of Minnesota Nanoimprint lithography
US6518189B1 (en) 1995-11-15 2003-02-11 Regents Of The University Of Minnesota Method and apparatus for high density nanostructures
US6068751A (en) 1995-12-18 2000-05-30 Neukermans; Armand P. Microfluidic valve and integrated microfluidic system
WO1997022636A2 (en) 1995-12-20 1997-06-26 E.I. Du Pont De Nemours And Company Iodonitriles as chain transfer agents in the manufacture of perfluoropolymers
US6355198B1 (en) 1996-03-15 2002-03-12 President And Fellows Of Harvard College Method of forming articles including waveguides via capillary micromolding and microtransfer molding
WO1997035906A1 (en) 1996-03-27 1997-10-02 Novartis Ag High water content porous polymer
US5942443A (en) 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
US5939291A (en) 1996-06-14 1999-08-17 Sarnoff Corporation Microfluidic method for nucleic acid amplification
NZ333346A (en) 1996-06-28 2000-03-27 Caliper Techn Corp High-throughput screening assay systems in microscale fluidic devices
IT1292424B1 (en) 1996-07-18 1999-02-08 Hoffmann La Roche OSSOPIRROLO-PIRROLDERIVATI
US6753131B1 (en) 1996-07-22 2004-06-22 President And Fellows Of Harvard College Transparent elastomeric, contact-mode photolithography mask, sensor, and wavefront engineering element
GB9623185D0 (en) 1996-11-09 1997-01-08 Epigem Limited Improved micro relief element and preparation thereof
AU7178698A (en) 1996-11-15 1998-06-03 Advanced Bio Surfaces, Inc. Biomaterial system for in situ tissue repair
US6027630A (en) 1997-04-04 2000-02-22 University Of Southern California Method for electrochemical fabrication
US6391622B1 (en) 1997-04-04 2002-05-21 Caliper Technologies Corp. Closed-loop biochemical analyzers
US6091433A (en) 1997-06-11 2000-07-18 Eastman Kodak Company Contact microfluidic printing apparatus
US6833242B2 (en) 1997-09-23 2004-12-21 California Institute Of Technology Methods for detecting and sorting polynucleotides based on size
US5993611A (en) 1997-09-24 1999-11-30 Sarnoff Corporation Capacitive denaturation of nucleic acid
US6012902A (en) 1997-09-25 2000-01-11 Caliper Technologies Corp. Micropump
US6334676B1 (en) 1997-09-29 2002-01-01 Eastman Kodak Company Using colorant precursors and reactants in microfluidic printing
IT1296968B1 (en) 1997-12-15 1999-08-03 Ausimont Spa FLUORINATED THERMOPLASTIC ELASTOMERS
US6451396B1 (en) 1998-02-13 2002-09-17 Gore Enterprise Holdings, Inc. Flexure endurant composite elastomer compositions
US6100541A (en) 1998-02-24 2000-08-08 Caliper Technologies Corporation Microfluidic devices and systems incorporating integrated optical elements
US6719868B1 (en) 1998-03-23 2004-04-13 President And Fellows Of Harvard College Methods for fabricating microfluidic structures
US6444474B1 (en) 1998-04-22 2002-09-03 Eltron Research, Inc. Microfluidic system for measurement of total organic carbon
US6274089B1 (en) 1998-06-08 2001-08-14 Caliper Technologies Corp. Microfluidic devices, systems and methods for performing integrated reactions and separations
US6529835B1 (en) 1998-06-25 2003-03-04 Caliper Technologies Corp. High throughput methods, systems and apparatus for performing cell based screening assays
US6027595A (en) 1998-07-02 2000-02-22 Samsung Electronics Co., Ltd. Method of making optical replicas by stamping in photoresist and replicas formed thereby
US6121404A (en) 1998-07-06 2000-09-19 Dow Corning Corporation β-diketo functional organosilicon compounds
US6132685A (en) 1998-08-10 2000-10-17 Caliper Technologies Corporation High throughput microfluidic systems and methods
US6447724B1 (en) 1998-08-11 2002-09-10 Caliper Technologies Corp. DNA sequencing using multiple fluorescent labels being distinguishable by their decay times
US6607683B1 (en) 1998-09-04 2003-08-19 Bruce E. Harrington Methods and apparatus for producing manufactured articles having natural characteristics
US6482306B1 (en) 1998-09-22 2002-11-19 University Of Washington Meso- and microfluidic continuous flow and stopped flow electroösmotic mixer
JP2002526103A (en) 1998-10-08 2002-08-20 アストラゼネカ・アクチエボラーグ Micro-assembled cell injector
US6591852B1 (en) 1998-10-13 2003-07-15 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
JP3015883B1 (en) 1998-10-26 2000-03-06 東京大学長 Preparation method of ultrafine particle structure
EP1003078A3 (en) 1998-11-17 2001-11-07 Corning Incorporated Replicating a nanoscale pattern
US6300042B1 (en) 1998-11-24 2001-10-09 Motorola, Inc. Lithographic printing method using a low surface energy layer
US6247986B1 (en) 1998-12-23 2001-06-19 3M Innovative Properties Company Method for precise molding and alignment of structures on a substrate using a stretchable mold
US6749814B1 (en) 1999-03-03 2004-06-15 Symyx Technologies, Inc. Chemical processing microsystems comprising parallel flow microreactors and methods for using same
US6334960B1 (en) 1999-03-11 2002-01-01 Board Of Regents, The University Of Texas System Step and flash imprint lithography
JP4304754B2 (en) 1999-03-24 2009-07-29 住友電気工業株式会社 Manufacturing method of ceramic parts having fine structure
US6818112B2 (en) 1999-04-20 2004-11-16 Target Discovery, Inc. Protein separation via multidimensional electrophoresis
US6592821B1 (en) 1999-05-17 2003-07-15 Caliper Technologies Corp. Focusing of microparticles in microfluidic systems
US6406605B1 (en) 1999-06-01 2002-06-18 Ysi Incorporated Electroosmotic flow controlled microfluidic devices
JP3370044B2 (en) 1999-06-03 2003-01-27 東海化成工業株式会社 Skin, manufacturing method thereof, manufacturing method of airbag door skin, and airbag door structure
US6306563B1 (en) 1999-06-21 2001-10-23 Corning Inc. Optical devices made from radiation curable fluorinated compositions
US7306672B2 (en) 2001-04-06 2007-12-11 California Institute Of Technology Microfluidic free interface diffusion techniques
MXPA01012959A (en) 1999-06-28 2002-07-30 California Inst Of Techn Microfabricated elastomeric valve and pump systems.
US6444106B1 (en) 1999-07-09 2002-09-03 Orchid Biosciences, Inc. Method of moving fluid in a microfluidic device
US6613581B1 (en) 1999-08-26 2003-09-02 Caliper Technologies Corp. Microfluidic analytic detection assays, devices, and integrated systems
US6517995B1 (en) 1999-09-14 2003-02-11 Massachusetts Institute Of Technology Fabrication of finely featured devices by liquid embossing
DE19946916A1 (en) 1999-09-30 2001-04-26 Abb Research Ltd Mold release agent for thermoset molded parts
WO2001026813A2 (en) 1999-10-08 2001-04-19 Micronics, Inc. Microfluidics without electrically of mechanically operated pumps
US6875619B2 (en) 1999-11-12 2005-04-05 Motorola, Inc. Microfluidic devices comprising biochannels
US6575562B1 (en) 1999-11-16 2003-06-10 Lexmark International, Inc. Performance inkjet printhead chip layouts and assemblies
US20030205552A1 (en) 1999-11-17 2003-11-06 The Regents Of The University Of California Method of forming a membrane with nanometer scale pores and application to biofiltration
TW562755B (en) 1999-12-31 2003-11-21 Ibm Stamp device for printing a pattern on a surface of a substrate
AU2610201A (en) 2000-01-06 2001-07-16 Caliper Technologies Corporation Ultra high throughput sampling and analysis systems and methods
WO2001053889A1 (en) 2000-01-21 2001-07-26 Obducat Aktiebolag A mold for nano imprinting
US6294450B1 (en) 2000-03-01 2001-09-25 Hewlett-Packard Company Nanoscale patterning for the formation of extensive wires
US6358387B1 (en) 2000-03-27 2002-03-19 Caliper Technologies Corporation Ultra high throughput microfluidic analytical systems and methods
US6409832B2 (en) 2000-03-31 2002-06-25 Micronics, Inc. Protein crystallization in microfluidic structures
US6335224B1 (en) 2000-05-16 2002-01-01 Sandia Corporation Protection of microelectronic devices during packaging
US6686184B1 (en) 2000-05-25 2004-02-03 President And Fellows Of Harvard College Patterning of surfaces utilizing microfluidic stamps including three-dimensionally arrayed channel networks
US6645432B1 (en) 2000-05-25 2003-11-11 President & Fellows Of Harvard College Microfluidic systems including three-dimensionally arrayed channel networks
US7351376B1 (en) 2000-06-05 2008-04-01 California Institute Of Technology Integrated active flux microfluidic devices and methods
EP1297077B1 (en) 2000-06-22 2005-12-14 DSM IP Assets B.V. Radiation curable colored coating composition
US6649715B1 (en) 2000-06-27 2003-11-18 Clemson University Fluoropolymers and methods of applying fluoropolymers in molding processes
US6558803B1 (en) * 2000-07-03 2003-05-06 Adhesives Research Inc. Ambifunctional perfluorinated polyethers
AU2001284896A1 (en) 2000-08-14 2002-02-25 Surface Logix, Inc. Deformable stamp for patterning three-dimensional surfaces
US6620196B1 (en) 2000-08-30 2003-09-16 Sdgi Holdings, Inc. Intervertebral disc nucleus implants and methods
US6508988B1 (en) 2000-10-03 2003-01-21 California Institute Of Technology Combinatorial synthesis system
US6512063B2 (en) 2000-10-04 2003-01-28 Dupont Dow Elastomers L.L.C. Process for producing fluoroelastomers
AU2001296551A1 (en) 2000-10-05 2002-04-15 E.I. Du Pont De Nemours And Company Polymeric microfabricated fluidic device suitable for ultraviolet detection
AU2001297642A1 (en) 2000-10-12 2002-09-04 Board Of Regents, The University Of Texas System Template for room temperature, low pressure micro- and nano-imprint lithography
AU2001295333A1 (en) 2000-10-16 2002-04-29 Hernan Miguez Method of self-assembly and optical applications of crystalline colloidal patterns on substrates
US7294294B1 (en) 2000-10-17 2007-11-13 Seagate Technology Llc Surface modified stamper for imprint lithography
JP4012680B2 (en) 2000-10-26 2007-11-21 信越化学工業株式会社 Organosilicon compound
IL155583A0 (en) 2000-10-26 2003-11-23 Alza Corp Transdermal drug delivery devices having coated microprotrusions
US6770721B1 (en) 2000-11-02 2004-08-03 Surface Logix, Inc. Polymer gel contact masks and methods and molds for making same
US7374906B2 (en) 2000-11-08 2008-05-20 Surface Logix, Inc. Biological assays using gradients formed in microfluidic systems
FR2817148B1 (en) 2000-11-30 2005-05-20 Oreal COSMETIC COMPOSITION CONTAINING MINERAL FILTERS
WO2002053290A2 (en) 2001-01-08 2002-07-11 President And Fellows Of Harvard College Valves and pumps for microfluidic systems and method for making microfluidic systems
WO2002055188A2 (en) 2001-01-10 2002-07-18 Memorial Sloan-Kettering Cancer Center System and process for microfluidics-based automated chemistry
US6422528B1 (en) 2001-01-17 2002-07-23 Sandia National Laboratories Sacrificial plastic mold with electroplatable base
JP2002214414A (en) 2001-01-22 2002-07-31 Omron Corp Optical element with thin resin film having micro-rugged pattern, method for producing the same and apparatus therefor
MXPA03006220A (en) 2001-01-24 2003-09-22 Huntsman Int Llc Molded foam articles prepared with reduced mold residence time and improved quality.
US6929899B2 (en) 2001-01-25 2005-08-16 E. I. Du Pont De Nemours And Company Fluorinated photopolymer composition and waveguide device
US6689900B2 (en) 2001-02-09 2004-02-10 E. I. Du Pont De Nemours And Company Fluorinated crosslinker and composition
JP2002268057A (en) 2001-03-06 2002-09-18 Omron Corp Optical device with resin thin film having micro uneven pattern, and method and device for manufacturing reflecting plate
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
US6632385B2 (en) 2001-03-23 2003-10-14 First Quality Nonwovens, Inc. Condrapable hydrophobic nonwoven web and method of making same
US6752922B2 (en) 2001-04-06 2004-06-22 Fluidigm Corporation Microfluidic chromatography
US20020164816A1 (en) 2001-04-06 2002-11-07 California Institute Of Technology Microfluidic sample separation device
WO2004069983A2 (en) 2002-08-19 2004-08-19 Bioprocessors Corporation Microreactor architecture and methods
US20040132166A1 (en) 2001-04-10 2004-07-08 Bioprocessors Corp. Determination and/or control of reactor environmental conditions
US20050120902A1 (en) 2001-04-25 2005-06-09 David Adams Edge transfer lithography
WO2002091028A2 (en) 2001-05-03 2002-11-14 Colorado School Of Mines Devices employing colloidal-sized particles
US6964793B2 (en) 2002-05-16 2005-11-15 Board Of Regents, The University Of Texas System Method for fabricating nanoscale patterns in light curable compositions using an electric field
US6737489B2 (en) 2001-05-21 2004-05-18 3M Innovative Properties Company Polymers containing perfluorovinyl ethers and applications for such polymers
US6729352B2 (en) 2001-06-07 2004-05-04 Nanostream, Inc. Microfluidic synthesis devices and methods
US6656398B2 (en) 2001-06-19 2003-12-02 Corning Incorporated Process of making a pattern in a film
US20030006527A1 (en) 2001-06-22 2003-01-09 Rabolt John F. Method of fabricating micron-and submicron-scale elastomeric templates for surface patterning
SE519573C2 (en) 2001-07-05 2003-03-11 Obducat Ab Stamp with anti-adhesive layer as well as ways of making and ways to repair such a stamp
WO2003015890A1 (en) 2001-08-20 2003-02-27 President And Fellows Of Harvard College Fluidic arrays and method of using
US6953653B2 (en) 2001-08-30 2005-10-11 Clemson University Fluoropolymer compositions, optical devices, and methods for fabricating optical devices
US6803568B2 (en) 2001-09-19 2004-10-12 Predicant Biosciences, Inc. Multi-channel microfluidic chip for electrospray ionization
WO2003035932A1 (en) * 2001-09-25 2003-05-01 Minuta Technology Co., Ltd. Method for forming a micro-pattern on a substrate by using capillary force
US6804062B2 (en) 2001-10-09 2004-10-12 California Institute Of Technology Nonimaging concentrator lens arrays and microfabrication of the same
US6936181B2 (en) 2001-10-11 2005-08-30 Kovio, Inc. Methods for patterning using liquid embossing
US20030071016A1 (en) 2001-10-11 2003-04-17 Wu-Sheng Shih Patterned structure reproduction using nonsticking mold
US20030156991A1 (en) 2001-10-23 2003-08-21 William Marsh Rice University Optomechanically-responsive materials for use as light-activated actuators and valves
US6554591B1 (en) 2001-11-26 2003-04-29 Motorola, Inc. Micropump including ball check valve utilizing ceramic technology and method of fabrication
US20030150716A1 (en) 2001-11-28 2003-08-14 Hua Zonglu Susan Electrochemically driven monolithic microfluidic systems
JP3896837B2 (en) * 2001-12-11 2007-03-22 ダイキン工業株式会社 Thermoplastic resin composition, laminated resin molded product, multilayer molded product, and fluorine-containing resin molded product
AU2003217184A1 (en) 2002-01-11 2003-09-02 Massachusetts Institute Of Technology Microcontact printing
EP1333680A3 (en) 2002-01-16 2007-06-13 Koninklijke Philips Electronics N.V. Digital image processing method
US6653030B2 (en) 2002-01-23 2003-11-25 Hewlett-Packard Development Company, L.P. Optical-mechanical feature fabrication during manufacture of semiconductors and other micro-devices and nano-devices that include micron and sub-micron features
US6581441B1 (en) 2002-02-01 2003-06-24 Perseptive Biosystems, Inc. Capillary column chromatography process and system
US6814859B2 (en) 2002-02-13 2004-11-09 Nanostream, Inc. Frit material and bonding method for microfluidic separation devices
CN100528363C (en) 2002-02-13 2009-08-19 安捷伦科技有限公司 Microfluidic separation column devices and preparation method thereof
KR100487025B1 (en) * 2002-02-28 2005-05-11 주식회사 루밴틱스 Photo-curable resin composition for optical waveguide and optical waveguide prepared therefrom
US6869557B1 (en) 2002-03-29 2005-03-22 Seagate Technology Llc Multi-level stamper for improved thermal imprint lithography
GB0208687D0 (en) 2002-04-16 2002-05-29 Davis John B Elastomer-glass fluid control elements
US6656308B2 (en) 2002-04-22 2003-12-02 International Business Machines Corporation Process of fabricating a precision microcontact printing stamp
US6783717B2 (en) 2002-04-22 2004-08-31 International Business Machines Corporation Process of fabricating a precision microcontact printing stamp
US6699347B2 (en) 2002-05-20 2004-03-02 The Procter & Gamble Company High speed embossing and adhesive printing process
US6849558B2 (en) 2002-05-22 2005-02-01 The Board Of Trustees Of The Leland Stanford Junior University Replication and transfer of microstructures and nanostructures
US6932934B2 (en) 2002-07-11 2005-08-23 Molecular Imprints, Inc. Formation of discontinuous films during an imprint lithography process
US7442336B2 (en) 2003-08-21 2008-10-28 Molecular Imprints, Inc. Capillary imprinting technique
US6900881B2 (en) 2002-07-11 2005-05-31 Molecular Imprints, Inc. Step and repeat imprint lithography systems
US7381471B2 (en) 2002-07-15 2008-06-03 University Of Virginia Patent Foundation Hybrid polymers for functional tuning of microfluidic device surfaces
US6817373B2 (en) 2002-07-26 2004-11-16 Applera Corporation One-directional microball valve for a microfluidic device
US20040028804A1 (en) 2002-08-07 2004-02-12 Anderson Daniel G. Production of polymeric microarrays
KR100480338B1 (en) 2002-08-08 2005-03-30 한국전자통신연구원 Microfluidic devices for the controlled movements of solution
US6936194B2 (en) 2002-09-05 2005-08-30 Molecular Imprints, Inc. Functional patterning material for imprint lithography processes
US7094345B2 (en) 2002-09-09 2006-08-22 Cytonome, Inc. Implementation of microfluidic components, including molecular fractionation devices, in a microfluidic system
US20040053237A1 (en) 2002-09-13 2004-03-18 Yingjie Liu Microfluidic channels with attached biomolecules
CN100477319C (en) 2002-09-19 2009-04-08 大金工业株式会社 Material with pattern surface for use as template and process for producing the same
US20040065252A1 (en) 2002-10-04 2004-04-08 Sreenivasan Sidlgata V. Method of forming a layer on a substrate to facilitate fabrication of metrology standards
US6755984B2 (en) 2002-10-24 2004-06-29 Hewlett-Packard Development Company, L.P. Micro-casted silicon carbide nano-imprinting stamp
US6811385B2 (en) 2002-10-31 2004-11-02 Hewlett-Packard Development Company, L.P. Acoustic micro-pump
US7022381B2 (en) * 2002-11-01 2006-04-04 Sandia National Laboratories Method for producing high dielectric strength microvalves
US7750059B2 (en) 2002-12-04 2010-07-06 Hewlett-Packard Development Company, L.P. Polymer solution for nanoimprint lithography to reduce imprint temperature and pressure
US7094354B2 (en) 2002-12-19 2006-08-22 Bayer Healthcare Llc Method and apparatus for separation of particles in a microfluidic device
TWI299101B (en) * 2003-01-30 2008-07-21 Sipix Imaging Inc High performance capsules for electrophoretic displays
US6808814B2 (en) 2003-03-18 2004-10-26 Xerox Corporation Blended fluorosilicone release agent for polymeric fuser members
US6945116B2 (en) 2003-03-19 2005-09-20 California Institute Of Technology Integrated capacitive microfluidic sensors method and apparatus
US20040202865A1 (en) 2003-04-08 2004-10-14 Andrew Homola Release coating for stamper
US7820030B2 (en) 2003-04-16 2010-10-26 Handylab, Inc. System and method for electrochemical detection of biological compounds
US7070406B2 (en) 2003-04-29 2006-07-04 Hewlett-Packard Development Company, L.P. Apparatus for embossing a flexible substrate with a pattern carried by an optically transparent compliant media
US6808646B1 (en) 2003-04-29 2004-10-26 Hewlett-Packard Development Company, L.P. Method of replicating a high resolution three-dimensional imprint pattern on a compliant media of arbitrary size
US6860956B2 (en) 2003-05-23 2005-03-01 Agency For Science, Technology & Research Methods of creating patterns on substrates and articles of manufacture resulting therefrom
US7530795B2 (en) 2003-06-13 2009-05-12 Canon Kabushiki Kaisha Fluid control mechanism
NL1023717C2 (en) 2003-06-20 2004-12-21 Fei Co Preparation carrier for carrying a preparation to be irradiated with an electron beam.
US7042649B2 (en) 2003-08-11 2006-05-09 California Institute Of Technology Microfabricated rubber microscope using soft solid immersion lenses
US20050038180A1 (en) 2003-08-13 2005-02-17 Jeans Albert H. Silicone elastomer material for high-resolution lithography
EP1694731B1 (en) * 2003-09-23 2012-03-28 University Of North Carolina At Chapel Hill Photocurable perfluoropolyethers for use as novel materials in microfluidic devices
US7236664B2 (en) 2003-09-29 2007-06-26 California Institute Of Technology Replica micro-resonator and method of fabrication
JP4414188B2 (en) 2003-09-30 2010-02-10 大日本印刷株式会社 Laminate with improved hard coat layer slipperiness
US7191508B2 (en) 2003-09-30 2007-03-20 Hitachi Global Storage Technologies Netherlands B.V. Method for manufacturing thin-film magnetic head sliders
JP4737368B2 (en) 2003-11-21 2011-07-27 東ソー株式会社 Resin composition for release film and release film
JP6067954B2 (en) 2003-12-19 2017-01-25 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｎｏｒｔｈ Ｃａｒｏｌｉｎａ Ａｔ Ｃｈａｐｅｌ Ｈｉｌｌ Nano-sized article and nano-sized article manufactured by a method for producing a separation structure using soft lithography or imprint lithography
US20050142315A1 (en) 2003-12-24 2005-06-30 Desimone Joseph M. Liquid perfluoropolymers and medical applications incorporating same
CA2555912A1 (en) * 2004-02-13 2005-09-15 The University Of North Carolina At Chapel Hill Functional materials and novel methods for the fabrication of microfluidic devices
DE102004008772A1 (en) * 2004-02-23 2005-09-08 Institut für Neue Materialien Gemeinnützige GmbH Abrasion resistant and alkali resistant low energy surface coatings or moldings
JP2007536107A (en) * 2004-05-04 2007-12-13 ミヌタ・テクノロジー・カンパニー・リミテッド Mold using non-crystalline fluororesin and method for producing the same
US7264669B1 (en) 2005-02-03 2007-09-04 Tribofilm Research, Inc. Scratch resistant gradient coating and coated articles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5412034A (en) * 1993-10-26 1995-05-02 E. I. Du Pont De Nemours And Company Curable elastomeric blends
US5459202A (en) * 1994-06-30 1995-10-17 E. I. Du Pont De Nemours And Company Elastomer seal

Also Published As

Publication number Publication date
US8158728B2 (en) 2012-04-17
EP2537657A3 (en) 2016-05-04
EP2537657A2 (en) 2012-12-26
EP1922364A2 (en) 2008-05-21
US20090281250A1 (en) 2009-11-12
WO2007021762A2 (en) 2007-02-22
US20120256354A1 (en) 2012-10-11
US8444899B2 (en) 2013-05-21
EP1922364A4 (en) 2010-04-21
US20130228950A1 (en) 2013-09-05

Similar Documents

Publication Publication Date Title
WO2007021762A3 (en) Methods and materials for fabricating microfluidic devices
IL187873A0 (en) Surface functional electro-textile with functionality modulation capability, methods for making the same, and applications incorporatiing the same
WO2009032117A3 (en) Reactive surface on a polymeric substrate
WO2005012874A3 (en) Nanostructured material transport devices and their fabrication by application of molecular coatings to nanoscale channels
WO2009094663A3 (en) Photovoltaic devices having metal oxide electron-transport layers
WO2011141850A3 (en) Panel and methods for manufacturing panels
ATE542843T1 (en) BARRIER FILM AND DEVICE
WO2008133864A3 (en) Mass production of micro-optical devices, corresponding tools, and resultant structures
ZA200711061B (en) Methods of preparing high orientation nanoparticle-containing sheets and films using ionic liquids, and the sheets and films produced thereby
EP2014700A4 (en) Polymerizable composition, resin using the same and optical component
WO2010078527A3 (en) Multilayer polymeric articles and methods for making same
WO2007133609A3 (en) Porous composite membrane materials and applications thereof
WO2009067636A3 (en) Modified insulin polypeptides and their uses
WO2009152120A3 (en) Microwave energy interactive structure with microapertures
WO2008109207A3 (en) Methods and devices for biomolecular arrays
WO2007050702A3 (en) Immunogenic compositions and methods of use
WO2007134330A3 (en) Multi-post structures
EP1736520A4 (en) Resin composition and semiconductor devices made by using the same
EP1757442A3 (en) Articles comprising nanoparticles
WO2008139310A3 (en) Method for manufacturing panels and panel hereby obtained
DE602006017429D1 (en) ABSORBENT ARTICLES WITH HEAT-PLATED SUPER-SEALABLE POLYMER MATERIALS
WO2009062516A3 (en) Photocatalytic boards or panels and a method of manufacturing thereof
EP2343125A4 (en) Hydrophilic films and components and structures using same
WO2010022324A3 (en) Methods of patterning paper
EP2154204A4 (en) Crosslinked fluorine-containing elastomer fine particle, method for producing the same, and composition

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200680037505.9

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2006801056

Country of ref document: EP

DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)
WWE Wipo information: entry into national phase

Ref document number: 12063284

Country of ref document: US

DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)