WO2007017893B1 - Preparation d'une nouvelle forme cristalline de perindopril erbumine monohydrate - Google Patents

Preparation d'une nouvelle forme cristalline de perindopril erbumine monohydrate

Info

Publication number
WO2007017893B1
WO2007017893B1 PCT/IN2006/000155 IN2006000155W WO2007017893B1 WO 2007017893 B1 WO2007017893 B1 WO 2007017893B1 IN 2006000155 W IN2006000155 W IN 2006000155W WO 2007017893 B1 WO2007017893 B1 WO 2007017893B1
Authority
WO
WIPO (PCT)
Prior art keywords
crystalline form
formula
process according
perindopril erbumine
novel crystalline
Prior art date
Application number
PCT/IN2006/000155
Other languages
English (en)
Other versions
WO2007017893A2 (fr
WO2007017893A3 (fr
Inventor
Ashish Ujagare
D A Kochrekar
Pushpalata Sarjekar
Original Assignee
Arch Pharmalabs Ltd
Ashish Ujagare
D A Kochrekar
Pushpalata Sarjekar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arch Pharmalabs Ltd, Ashish Ujagare, D A Kochrekar, Pushpalata Sarjekar filed Critical Arch Pharmalabs Ltd
Publication of WO2007017893A2 publication Critical patent/WO2007017893A2/fr
Publication of WO2007017893A3 publication Critical patent/WO2007017893A3/fr
Publication of WO2007017893B1 publication Critical patent/WO2007017893B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

L'invention concerne une nouvelle forme cristalline de périndopril erbumine monohydrate de la formule (III) possédant les valeurs 2? caractéristiques 8.87, 9.43, 9.60, 15.36, 15.96, 16.02, 19.97, 21.00, 21.13, 21.5, 22.14, 24.13, et 26.48. L'invention porte, en particulier, sur un procédé de préparation de la nouvelle forme cristalline de périndopril erbumine monohydrate de la formule (III).
PCT/IN2006/000155 2005-05-05 2006-05-04 Preparation d'une nouvelle forme cristalline de perindopril erbumine monohydrate WO2007017893A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN562MU2005 2005-05-05
IN562/MUM/2005 2005-05-05

Publications (3)

Publication Number Publication Date
WO2007017893A2 WO2007017893A2 (fr) 2007-02-15
WO2007017893A3 WO2007017893A3 (fr) 2007-05-10
WO2007017893B1 true WO2007017893B1 (fr) 2007-06-21

Family

ID=37726988

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2006/000155 WO2007017893A2 (fr) 2005-05-05 2006-05-04 Preparation d'une nouvelle forme cristalline de perindopril erbumine monohydrate

Country Status (1)

Country Link
WO (1) WO2007017893A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008120241A2 (fr) * 2007-03-29 2008-10-09 Ipca Laboratories Limited Nouveaux solvates alcooliques de périndopril erbumine
SI22543A (sl) * 2007-06-27 2008-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove soli perindoprila
PT105315B (pt) 2010-09-29 2013-01-16 Inst Superior Tecnico Uma nova forma cristalina hidratada de erbumina de perindopril, métodos para a sua preparação e sua utilização em preparações farmacêuticas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2395195A (en) * 2002-11-18 2004-05-19 Cipla Ltd Preparation of perindopril from carboxy-protected precursor, & perindopril monohydrates for use as angiotensin converting enzyme (ACE) inhibitors
BRPI0411966A (pt) * 2003-06-24 2006-08-29 Servier Lab formas cristalinas de perindopril erbumina
AU2003263584A1 (en) * 2003-08-21 2005-03-10 Hetero Drugs Limited Process for pure perindopril tert-butylamine salt
SI21881A (sl) * 2004-10-15 2006-04-30 Diagen, Smartno Pri Ljubljani, D.O.O. Nove kristalne oblike perindopril erbumin hidratov, postopek za njihovo pripravo in farmacevtske oblike, ki vsebujejo te spojine

Also Published As

Publication number Publication date
WO2007017893A2 (fr) 2007-02-15
WO2007017893A3 (fr) 2007-05-10

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