WO2007006139A1 - Dispositif d’occlusion d’anévrisme - Google Patents

Dispositif d’occlusion d’anévrisme Download PDF

Info

Publication number
WO2007006139A1
WO2007006139A1 PCT/CA2006/001118 CA2006001118W WO2007006139A1 WO 2007006139 A1 WO2007006139 A1 WO 2007006139A1 CA 2006001118 W CA2006001118 W CA 2006001118W WO 2007006139 A1 WO2007006139 A1 WO 2007006139A1
Authority
WO
WIPO (PCT)
Prior art keywords
mesh
aneurysm
therapeutic element
aneurysm cavity
cavity
Prior art date
Application number
PCT/CA2006/001118
Other languages
English (en)
Inventor
Thomas Freier
Rivelino Montenegro
Alex Goraltchouk
Original Assignee
Smart Biotech Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smart Biotech Inc. filed Critical Smart Biotech Inc.
Publication of WO2007006139A1 publication Critical patent/WO2007006139A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214—Coils or wires
    • A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
    • A61B17/12172—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure having a pre-set deployed three-dimensional shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
    • A61B17/12177—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12181—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
    • A61B17/12186—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices liquid materials adapted to be injected
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12181—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
    • A61B17/1219—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices expandable in contact with liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831—Material properties
    • A61B2017/00867—Material properties shape memory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831—Material properties
    • A61B2017/00898—Material properties expandable upon contact with fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205—Introduction devices
    • A61B2017/12054—Details concerning the detachment of the occluding device from the introduction device
    • A61B2017/12063—Details concerning the detachment of the occluding device from the introduction device electrolytically detachable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205—Introduction devices
    • A61B2017/12054—Details concerning the detachment of the occluding device from the introduction device
    • A61B2017/12095—Threaded connection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes

Definitions

  • At least part of the mesh or the at least one therapeutic element may be coated or embedded with a bioactive agent. At least part of the mesh or the at least one therapeutic element may be coated or embedded with a biodegradable coating. At least part of the mesh or the at least one therapeutic element may be coated or embedded with an expandable hydrogel. At least part of the mesh or the at least one therapeutic element may be coated or embedded with a substance reactive with a liquid embolic agent to promote faster gelation or setting. At least part of the mesh or the at least one therapeutic element may be coated or embedded with a thrombogenic substance. Alternatively, at least part of the mesh or the at least one therapeutic element may be coated or embedded with a non-thrombogenic substance.
  • the therapeutic element may be itself an expandable element, in which case, it expands concurrently with the mesh.
  • a shape memory element may be used, which self-expands into a previously memorized shape upon deployment of the device.
  • the expandable element may be preferably a thrombus promoting drug or a vessel wall healing drug, in which case, the expansion of the element resulting in delivery of the drug into the aneurysm cavity.
  • the device comprises: an enclosed three-dimensional structure of resilient mesh, the structure having: a collapsed state, in which the structure is relatively small and radially compact for delivery by a catheter into the aneurysm cavity; and an expanded state, in which the structure is relatively large and of a shape selected to substantially fill the aneurysm cavity without extending into a lumen of a vessel adjacent to the aneurysm cavity; the structure being capable of transition by self-expansion from the collapsed state to the expanded state within the aneurysm cavity to substantially fill the aneurysm cavity without extending into a lumen of a vessel adjacent to the aneurysm cavity.
  • Figures 3A-3D are schematic diagrams of a deployment sequence of a device according to a second embodiment of the present invention (containing a first type of embolism promoting element - in this case, hydrogel particles).
  • Figures 4A-4D are schematic diagrams of a deployment sequence of a device according to a third embodiment of the present invention (containing a second type of embolism promoting element - in this case, embolization coils)
  • a mesh 8 For deployment of a mesh 8, it will be inserted into a delivery catheter 10 and pushed through the catheter in a collapsed configuration (Fig. 2A). After releasing from the catheter 10 into the aneurysmal cavity 12, the mesh 8 expands to its memorized three- dimensional shape (Figs. 2B and 2C), and will finally be detached from the delivery wire 14 (Fig. 2D). It is important to note that the mesh structure does not significantly extend into the lumen of the adjacent vessel 16 (see Fig. 2D) so that the risk of thrombosis inside the lumen of the vessel is minimized.
  • Occlusion of the aneurysmal cavity is imparted by thrombosis and/or foreign-body reactions induced by the inserted mesh.
  • Thrombosis may also be imparted by providing an electrical current to the mesh for a pretermined period of time.
  • thrombosis may be imparted by coating the mesh with a thrombotic and/or cell- proliferative agent.
  • the agent which may be a drug, oligosaccharide, polysaccharide, lipid, peptide or protein, radioactive substance, or derivatives and combinations of agents, may be incorporated in a polymer layer coating the mesh entirely or partially.
  • Polymer coating can be performed in any of the well-known methods, such as dip- coating, spray-coating or brush-coating. Activation can also be by plasma modification.
  • the polymer coating itself without any additional agent may also serve as a means to impart thrombotic and/or cell-proliferative processes in order to control aneurysmal filling.
  • Non-degradable as well as degradable polymers such as those listed above may be suitable for coating the mesh with or without incorporation of thrombotic and/or cell- proliferative agents into the coating.
  • the three-dimensional mesh structure may contain embolization elements in its interior hollow part in order to control aneurysmal filling.
  • the mesh size and pattern may preferably be chosen to prevent any migration of the coils out of the mesh into the adjacent vessel.
  • embolization elements may also be inserted in a second step, from the same or a different catheter, into the mesh after it has already been deployed and expanded into the aneurysmal cavity.
  • hydrogels may be inserted through the holes of the mesh into its interior part when they are in the dried state (xerogels) providing a volume small enough for insertion. Under physiological conditions, the particles gain water and expand to a bigger volume which prevents their migration out of the mesh.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Surgical Instruments (AREA)

Abstract

La présente invention concerne un dispositif d’occlusion d’anévrisme. Le dispositif utilise une structure tridimensionnelle enfermée d’une mèche résiliente. La structure de mèche contient des éléments thérapeutiques chargés au préalable, des éléments soit favorisant le thrombus, soit cicatrisant la paroi des vaisseaux. La structure de mèche peut se dilater pour remplir la cavité de l’anévrisme sans s’étendre dans un vaisseau adjacent. La mèche permet que les éléments thérapeutiques soient progressivement exposés au fur et à mesure que la mèche se dilate ou est placée dans l’anévrisme. Un procédé pour déployer le dispositif en utilisant un cathéter est également proposé, ainsi qu’un procédé d’occlusion d’un anévrisme utilisant le dispositif.
PCT/CA2006/001118 2005-07-12 2006-07-12 Dispositif d’occlusion d’anévrisme WO2007006139A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69808005P 2005-07-12 2005-07-12
US60/698.080 2005-07-12

Publications (1)

Publication Number Publication Date
WO2007006139A1 true WO2007006139A1 (fr) 2007-01-18

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2006/001118 WO2007006139A1 (fr) 2005-07-12 2006-07-12 Dispositif d’occlusion d’anévrisme

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WO (1) WO2007006139A1 (fr)

Cited By (31)

* Cited by examiner, † Cited by third party
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WO2009052009A2 (fr) * 2007-10-15 2009-04-23 Boston Scientific Scimed, Inc. Systèmes d'ancrage à spires et leurs procédés d'utilisation
WO2010030991A1 (fr) * 2008-09-12 2010-03-18 Micrus Endovascular Corporation Dispositif et système auto-extensibles de remplissage d'anévrisme
WO2012092349A1 (fr) * 2010-12-30 2012-07-05 Cook Medical Technologies Llc Dispositif d'obturation à auto-déploiement
DE102011102933A1 (de) 2011-05-31 2012-12-06 Acandis Gmbh & Co. Kg Medizinisches Implantat zur Anordnung innerhalb eines Hohlkörpers, insbesondere eines Aneurysmas
DE102011102955A1 (de) 2011-05-31 2012-12-06 Acandis Gmbh & Co. Kg Medizinisches Implantat zur Anordnung eines Hohlkörpers, insbesondere eines Aneurysmas, und Verfahren zum Herstellen eines medizinischen Implantats
CN102954338A (zh) * 2011-08-15 2013-03-06 通用汽车环球科技运作有限责任公司 顺应性形状记忆物品
EP2665510A2 (fr) * 2011-01-17 2013-11-27 Novita Therapeutics, LLC Dispositif de pose de ballonnet métallique détachable, et procédé associé
EP2768424A1 (fr) * 2011-10-18 2014-08-27 Anaxiom Corporation Méthode et appareil pour traiter un patient par occlusion intentionnelle d'un vaisseau sanguin, et méthode et appareil pour induire une perte pondérale chez un patient par occlusion intentionnelle de l'artère coeliaque
WO2014159445A1 (fr) * 2013-03-13 2014-10-02 Lawrence Livermore National Security, Llc Dispositif de mousse en polymère à mémoire de forme pour traiter des anévrismes
JP2014532464A (ja) * 2011-10-27 2014-12-08 オクルテック ホールディング エージー 医療用インプラント、キット、および、医療用インプラントを形成するためのストランドの３次元織物を製造する方法
CN105007859A (zh) * 2012-12-26 2015-10-28 麦地那医药公司 用于血管缺陷的治疗的装置和方法
WO2015105459A3 (fr) * 2014-01-10 2015-11-12 Nanyang Technological University Dispositif d'embolisation et appareil pour l'embolisation d'un site vasculaire cible, et procédé associé
WO2017072695A1 (fr) * 2015-10-28 2017-05-04 Jayandiran Pillai Dispositif d'occlusion d'anévrisme
CN108354645A (zh) * 2012-11-13 2018-08-03 柯惠有限合伙公司 封堵装置
JP2020018858A (ja) * 2018-08-03 2020-02-06 デピュイ・シンセス・プロダクツ・インコーポレイテッド 塞栓用編組体のための渦巻状送達システム
WO2020190620A1 (fr) * 2019-03-15 2020-09-24 Sequent Medical, Inc. Dispositifs filamenteux pour le traitement de défauts vasculaires
CN112274206A (zh) * 2020-12-29 2021-01-29 北京泰杰伟业科技有限公司 一种水凝胶扰流装置及扰流装置输送系统
EP3777702A4 (fr) * 2018-03-28 2021-04-14 Shanghai MicroPort Medical (Group) Co., Ltd. Dispositif d'occlusion et son procédé de préparation
US11013516B2 (en) 2011-01-17 2021-05-25 Artio Medical, Inc. Expandable body device and method of use
US11033275B2 (en) 2014-09-17 2021-06-15 Artio Medical, Inc. Expandable body device and method of use
US11291453B2 (en) 2019-03-15 2022-04-05 Sequent Medical, Inc. Filamentary devices having a flexible joint for treatment of vascular defects
US11317921B2 (en) 2019-03-15 2022-05-03 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
WO2022222256A1 (fr) * 2021-04-21 2022-10-27 上海苏畅医疗科技有限公司 Dispositif d'occlusion d'anévrisme et son procédé de préparation
US11484318B2 (en) 2011-01-17 2022-11-01 Artio Medical, Inc. Expandable body device and method of use
WO2023050520A1 (fr) * 2021-09-28 2023-04-06 北京泰杰伟业科技有限公司 Dispositif de blocage de collet anévrysmal
US11633818B2 (en) 2019-11-04 2023-04-25 Covidien Lp Devices, systems, and methods for treatment of intracranial aneurysms
US11707371B2 (en) 2008-05-13 2023-07-25 Covidien Lp Braid implant delivery systems
US11723667B2 (en) 2013-08-16 2023-08-15 Microvention, Inc. Filamentary devices for treatment of vascular defects
US11844528B2 (en) 2008-04-21 2023-12-19 Covidien Lp Multiple layer filamentary devices for treatment of vascular defects
WO2024046551A1 (fr) * 2022-08-31 2024-03-07 Clearstream Technologies Limited Dispositif avp avec lobe/segment conçu pour remplir un sac anévrismal
US12023034B2 (en) 2020-03-11 2024-07-02 Microvention, Inc. Devices for treatment of vascular defects

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WO1999005977A1 (fr) * 1997-08-04 1999-02-11 Boston Scientific Corporation Systeme d'occlusion servant a reparer un anevrisme
WO2002051460A2 (fr) * 2000-12-27 2002-07-04 Scimed Life Systems, Inc. Matieres bioactives pour reparation d'un anevrisme
WO2003082128A1 (fr) * 2002-03-27 2003-10-09 Scimed Life Systems, Inc. Dispositif pour fond de cavite corporelle dilatable
WO2003086240A1 (fr) * 2002-04-12 2003-10-23 Boston Scientific Limited Dispositifs permettant de retenir des dispositifs pour l'occlusion vasculaire dans un anevrysme
WO2005060606A2 (fr) * 2003-12-10 2005-07-07 Neurovasx, Inc. Matiere et dispositif d'embolisation d'anevrisme

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999005977A1 (fr) * 1997-08-04 1999-02-11 Boston Scientific Corporation Systeme d'occlusion servant a reparer un anevrisme
WO2002051460A2 (fr) * 2000-12-27 2002-07-04 Scimed Life Systems, Inc. Matieres bioactives pour reparation d'un anevrisme
WO2003082128A1 (fr) * 2002-03-27 2003-10-09 Scimed Life Systems, Inc. Dispositif pour fond de cavite corporelle dilatable
WO2003086240A1 (fr) * 2002-04-12 2003-10-23 Boston Scientific Limited Dispositifs permettant de retenir des dispositifs pour l'occlusion vasculaire dans un anevrysme
WO2005060606A2 (fr) * 2003-12-10 2005-07-07 Neurovasx, Inc. Matiere et dispositif d'embolisation d'anevrisme

Cited By (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8585723B2 (en) 2007-10-15 2013-11-19 Boston Scientifc Scimed, Inc. Coil anchor systems and methods of use
WO2009052009A3 (fr) * 2007-10-15 2009-06-04 Boston Scient Scimed Inc Systèmes d'ancrage à spires et leurs procédés d'utilisation
WO2009052009A2 (fr) * 2007-10-15 2009-04-23 Boston Scientific Scimed, Inc. Systèmes d'ancrage à spires et leurs procédés d'utilisation
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