WO2006117430A1 - Préparations pour l'éclaircissement de la peau - Google Patents

Préparations pour l'éclaircissement de la peau Download PDF

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Publication number
WO2006117430A1
WO2006117430A1 PCT/FI2006/000139 FI2006000139W WO2006117430A1 WO 2006117430 A1 WO2006117430 A1 WO 2006117430A1 FI 2006000139 W FI2006000139 W FI 2006000139W WO 2006117430 A1 WO2006117430 A1 WO 2006117430A1
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WO
WIPO (PCT)
Prior art keywords
skin
cream
seed oil
skin care
care composition
Prior art date
Application number
PCT/FI2006/000139
Other languages
English (en)
Inventor
Baoru Yang
Vesa-Pekka Judin
Petri Määttä
Original Assignee
Aromtech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aromtech Ltd filed Critical Aromtech Ltd
Priority to ES06743508.1T priority Critical patent/ES2437035T3/es
Priority to EP06743508.1A priority patent/EP1909918B1/fr
Publication of WO2006117430A1 publication Critical patent/WO2006117430A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0212—Face masks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations

Definitions

  • the present invention relates to a use of composition comprising triglycerides of unsaturated fatty acids, a skin care composition and a method for lightening skin for cosmetic purposes.
  • Hyperpigmentation, chloasmata and senile spots are signs of ageing of the skin and ultraviolet (UV) exposure often results in hyperpigmentation, dyspigmentation, and uneven skin tones.
  • UV ultraviolet
  • Asian, African and Hispanic cultures there is also a strong desire of lighter skin tones.
  • ingredients and composition for skin lightening formulations and for formulations evening the skin tones There is therefore a great demand for ingredients and composition for skin lightening formulations and for formulations evening the skin tones.
  • moisture loss and increased skin sensitivity are often associated with sun/UV exposure and dryness and wrinkles are typical of aged skin.
  • Sunscreens such as titanium dioxide, zinc oxide and avobenzone are widely used to prevent hyper- and dyspigmentation caused by UV exposure. These compounds however present a significant risk of skin penetration.
  • the commonly used skin lightening ingredients are hydroquinone and kojic acid as inhibitors of melanin synthesis.
  • these ingredients are extremely unstable and lose their activity in the end product soon after opening of the package.
  • some derivatives of these compounds such as kojic dipalmitate have been used.
  • All trans-retinoic acid, alpha hydroxy acid and hydroxy acids from synthetic and natural sources are not effective in reducing melanin synthesis but are often used in combination with other lightening ingredients to improve the overall appearance of skin.
  • treatment of hyper- and dyspigmentation sometimes involves combined use of inhibitors of melanin synthesis and resurfacing measures such as chemical peels and laser treatment. These measures may damage the skin barrier system and result in moisture loss and an increased sensitivity of skin.
  • sun care products it is often not enough for sun care products to include only skin lightening ingredients. Other ingredients with moisturising and antioxidative activities are necessary due to the moisture loss and oxidative stress caused by sun exposure.
  • the present invention seeks to solve at least part of the problems of the prior art listed above.
  • One object of the present invention is thus to provide a lightening skin care composition that is safe for the user.
  • Another object is to provide an effective and natural skin care composition for skin lightening.
  • the present invention also has an object to provide a skin care composition that is useful as a skin lightening, a skin moisturising and an antioxidant composition.
  • the present invention relates to the use of composition comprising at least one triglyceride of at least one unsaturated fatty acid for manufacture of a product for skin lightening.
  • the present invention relates also to a skin care composition comprising a dermatologically acceptable additive and a pure seed oil derived from a plant selected from the group Rubus, Vaccinium, Oxycoccus, Fragaria, Hippophae, Echium, Hordeum, Avena, or a mixture thereof comprising at least one triglyceride of an unsaturated fatty acid, excluding however seed oil of Rubus chamaemorus.
  • the present invention relates to a method of lightening the skin for cosmetic purposes, where a skin care composition comprising at least one triglyceride of at least one unsaturated fatty acid is applied on a skin and allowed to act.
  • Fig. 5 shows results of Example 7.
  • the present invention relates to a use of a composition comprising at least one triglyceride of at least one unsaturated fatty acid for manufacture of a product for skin lightening.
  • Unsaturated fatty acids in the form of triglycerides have been previously assumed to be inactive in skin care products.
  • the present inventors have however surprisingly discovered that some special vegetable oils extremely rich in triglycerides of unsaturated fatty acids are active ingredients for skin care compositions intended for lightening, smoothing or whitening the skin colour of human objects. It is assumed, without being bound by the theory, that the triglycerides of the unsaturated fatty acids may reduce the biosynthesis of melanin resulting in a lighter skin tone and/or may help to disperse the melanin pigment and thus even the skin tone.
  • the said at least one unsaturated fatty acid is selected from the group consisting of linoleic acid and ⁇ - linolenic acid.
  • the inventors have found that these two unsaturated fatty acids in the form of triglycerides have a significant skin lightening effect. A mixture of triglycerides of these two acids can also be used.
  • linoleic acid does not comprise conjugated linoleic acids, which are structurally different fatty acids and also from different sources, such as from dairy products and synthetic sources.
  • Oils useful in manufacturing products for lightening and moisturising of the skin would typically contain a total content of linoleic acid [18:2(n - 6)] and ⁇ -linolenic acid [18:3(n - 3)] at levels of 20 - 90 %, preferably 60 - 9 0 %, of the total fatty acids.
  • One preferred fatty acid composition of the oils contains linoleic and ⁇ - linolenic acids at ratios from 2:1 to 1:2. According to one embodiment, said ratio is around 1 :1. Other ratios may naturally also be used.
  • triglyceride of unsaturated fatty acid is derived from natural oils of plant origin.
  • the plant can be selected from the group consisting of Rubus, Ribes, Vaccinium, Oxycoccus, Fragaria, Hippophae, Echium, Hordeum and Avena.
  • the natural oil is seed oil of Vaccinium vitis-idaea.
  • a beneficial composition of triglycerides of these acids can be found, for example, in the seed oils of the above mentioned plants.
  • a fruit pulp oil can be used.
  • mixtures of these natural oils can be used.
  • Mixture can comprise oils from two or more different plant genera, oils from two or more different plant species of the same genus or oils from seeds and fruit pulp, or any possible combination of these.
  • the seed oil which is used for manufacture of a product for skin lightening, is derived from seeds of a Vaccinium species that is selected from the group comprising species of blueberry, e.g. Vaccinium angustifolium, Vaccinium boreale, Vaccinium caesariense, Vaccinium corymbosum, Vaccinium darrowii, Vaccinium elliottii, Vaccinium formosum, Vaccinium fuscatum, Vaccinium hirsutum, Vaccinium koreanum, Vaccinium myrsinites, Vaccinium myrtilloides, Vaccinium pallidum, Vaccinium simulatum, Vaccinium tenellum, Vaccinium virgatum; species of bilberry, e.g.
  • blueberry e.g. Vaccinium angustifolium, Vaccinium boreale, Vaccinium caesariense, Vaccinium corymbosum, Vaccinium darrowii, Vaccinium elliottii, Vaccinium
  • oil from species of Hippophae e.g. Hippophae rhamnoides, Hippophae salicifolia, Hippophae tibetana, can be used.
  • skin care compositions it is meant for example cosmetic and dermatological compositions.
  • One embodiment of the present invention thus provides a skin care composition that is a natural skin-lightening agent with no skin- and membrane-irritating effects or other health risks.
  • the compositions are useful for example in formulations for sensitive skin type or for prolonged or continuous use.
  • skin care compositions according to the present invention can be used for multiple purposes, for example at the same time for skin lightening, moisturising, anti-ageing and UV- protection purposes due to the surprisingly multiple functions of the seed oils used.
  • the skin care composition according to the present invention thus comprises natural plant oil comprising at least one triglyceride of at least one unsaturated fatty acid.
  • one triglyceride comprises more than one type of unsaturated fatty acid.
  • the amount of the natural plant oil e.g. seed oil
  • the amount of the natural plant oil is 0.01 - 99.99, typically 0.05 - 50, more typically
  • oils of the selected plants are of natural origin, they can be used in relatively high concentrations without any adverse effects.
  • the natural plant oils have beneficial triglyceride compositions that are potent in skin lightening, thus making the amount of needed oil relatively small.
  • Triglycerides of unsaturated fatty acids derived from the natural plant oils, typically seed oils, mentioned above have been found out to be effective for example for lightening or evening skin tones. More specifically, triglycerides of unsaturated fatty acids derived from seed oils of Rubus (e.g. raspberry and cloudberry), Ribes (e.g. blackcurrant), Vaccinium (e.g. bilberry, blueberry, lingonberry, mountain bilberry, cranberry and arctic cranberry), Oxycoccus (e.g. cranberry), Fragaria (e.g. strawberry), Hippophae (e.g. sea buckthorn), Echium (e.g. echium), Hordeum (e.g. barley) and Avena (e.g. oat) have been found to be especially effective for lightening or evening skin tones.
  • Rubus e.g. raspberry and cloudberry
  • Ribes e.g. blackcurrant
  • Vaccinium
  • these oils are effective for moisturising skin and for restoring the skin barrier, and/or for UV protection, antioxidation and antiageing.
  • seed oils rich in triglycerides of unsaturated fatty acids e.g. seed oils from Rubus (e.g. raspberry and cloudberry), Ribes (e.g. blackcurrant), Vaccinium (e.g. bilberry, blueberry, lingonberry, mountain bilberry, arctic cranberry), Oxycoccus (e.g. cranberry) and Echium (e.g. echium) are effective for UV protection, antioxidation and anti-ageing of skin.
  • the skin composition may show other functions including moisturising and anti-ageing properties on top the skin lightening properties.
  • the skin care compositions according to the present invention is, according to one embodiment of the present invention, intended for skin lightening and may also include a use selected from the group of functions consisting of moisturising, restoring skin barrier, UV-protection, antioxidation, antiageing and mixtures thereof.
  • pure seed oil denotes oil comprising at least 95 weight-% seed oil, typically at least 99 weight-% seed oil, more typically 99.5 weight-% seeed oil, sometimes even 100 weight-% seed oil. Pure seed oil is typically totally solvent free and it does not contain any solid content or solid residues.
  • the skin care compositions of the present invention can be used for example in day creams, night creams, face and body lotions, body butters, skin peels, masks, and shower gels.
  • the targets of these products can be for example lightening, moisturising, anti-ageing, UV-protection including sun cream, sun lotion and creams and lotions for after sun application.
  • the dermatologically acceptable additive comprises other lightening ingredients, sunscreen ingredients, preservatives, antioxidants or their combinations.
  • the additive may be also emulsifier, stabilizer, preservative, UV filter, emollient, organic or mineral fillers.
  • the skin care composition is solvent free, thus making it very suitable for cosmetic purposes and minimising or even eliminating the risks of hypersensitivity or toxicity.
  • any other additives useful in skin care formulations may be used, such as kojic acid, hydroquinone, arbutin, free fatty acids, honey etc at safe levels. These compounds are typical examples of skin lightening ingredients.
  • said triglycerides of polyunsaturated fatty acids are used as such or in the form of natural oils of plant origin rich in polyunsaturated fatty acids for manufacture of a product for lightening or evening the skin tone. They are maybe used in combination with other skin lightening ingredients and sunscreens to produce enhanced lightening and UV protection efficacies on skin or to reduce the amount of other lightening ingredients and sunscreens in skin care formulations.
  • sunscreen ingredients are titanium dioxide and zinc oxide.
  • the natural plant oils mentioned in this invention include raw, semi-refined and refined oils, isolated by cold pressing and extraction with organic solvents, CO 2 and/or vegetable oils, from plant materials such as seeds, fruits, fruit flesh and peel, and press residues of fruits. Also oils isolated from juice of berries by mechanical methods may be used. Typically seed oils are preferred.
  • supercritical CO 2 extraction often has good quality due to the high extraction efficiency and the absence of harmful solvent residues in the oils extracted.
  • supercritical CO 2 -extracted oils are one preferred embodiment for use in high grade cosmetic and dermatological products for skin care.
  • said skin care compositions further comprise lightening and/or sun screen ingredients and/or added antioxidants.
  • One application of the present invention covers the use of natural oils of plant origin rich in triglycerides of polyunsaturated fatty acids and as active ingredients in skin care formulations for any purpose selected from the group consisting of skin lightening, moisturising, anti-ageing, radical scavenging, UV protection and combinations thereof.
  • the skin composition according to the present embodiment is applied regularly, e.g. once or twice a day. It can also be applied as a limited regime, lasting e.g. for a one week, two weeks, three weeks, four weeks, one month or two months etc.
  • the skin care composition is useful in whitening or lightening the overall skin tone, or whitening or lightening age spots or freckles.
  • As the skin care composition of the present invention is safe to use, it can be used for lightening of the skin of the whole body, not only face and/or hands. Furthermore, it can be used to lighten or whiten the skin of children or adolescents.
  • An emulsion cream composition for facial and throat skin care contains, in weight- %
  • cyclopentasiloxane 6.0 wt-% steareth-2 4.0 wt-% steareth-21 2.0 wt-% octyldodecanol 2.0 wt-% stearic acid 2.0 wt-% cetearyl alcohol 1.5 wt-% peg-30 dipolyhydroxystearate 1.0 wt-% tocopheryl acetate 1.0 wt-%
  • Vaccinium oxycoccos (Oxycoccus palustris), seed oil 1-10% phenoxyethanol 0.80 wt-% ppg-15 stearyl ether 0.60 wt-% panthenol 0.50 wt-% perfume 0.20 wt-% dimethicone/ vinyldimethicon crosspolymer 0.30 wt-% phospholipids 0.2 wt-% parabens 0.30 wt-% magnesium ascorbyl phosphate 0.10 wt-% tocopherol 0.05 wt-% glycerin 0.025 wt-% ascorbyl palmitate 0.05 wt-% sodium chloride 0.003 wt-% ascorbic acid 0.001 wt-% water in order to arrive at 100 wt-%
  • the described emulsion cream composition lightens, moisturizes, brightens and softens the skin. In addition it has antioxidative properties.
  • a ready-for-use emulsion cream composition for facial and throat skin care consists of (in weight-%):
  • sorbitan olivate 14.0 wt-% squalane 11.0 wt-% cyclopentasiloxane 8.0 wt-% glycerin 4.0 wt-% tocopheryl acetate 2.0 wt-% sodium chloride 1.5 wt-% C20-C40 alcohols 1.0 wt-% Ribes nigrum, seed oil 1-5%
  • Vaccinium myrtillus seed oil 0.01-10 wt-%
  • C20-C40 acid 0.85 wt-% phenoxyethanol 0.72 wt-% aluminium/magnesium hydroxide stearate 0.70 wt-% dimethicone/vinyldimethicone crosspolymer 0.30 wt-% perfume 0.20 wt-% parabens 0.30 wt-% polyethylene 0.15 wt-% phospholipids 0.15 wt-% retinol 0.05 wt-% tocopherol 0.05 wt-% ascorbyl palmitate 0.005 wt-% ascorbic acid 0.005 wt-% citric acid 0.001 wt-% retinyl palmitate 0.00001 wt-% water in order to arrive at 100 wt-%
  • the emulsion cream composition lightens skin tone, regenerates and revitalises skin. In addition, it reduces, softens and smoothes the fine lines in the skin.
  • An emulsion cream composition for intensive lightening and moisturising of facial and throat skin contains, in weight-%
  • cyclopentasiloxane 6.0 wt-% steareth-2 4.0 wt-% steareth-21 2.0 wt-% octyldodecanol 2.0 wt-% stearic acid 2.0 wt-% cetearyl alcohol 1.5 wt-% peg-30 dipolyhydroxystearate 1.0 wt-% tocopheryl acetate 1.0 wt-%
  • Vaccinium oxycoccos (Oxycoccus palustris), seed oil 1-10% honey 1 % phenoxyethanol 0.80 wt-% panthenol 0.50 wt-% perfume 0.35 wt-% dimethicone/ vinyldimethicon crosspolymer 0.28 wt-% phospholipids 1.0 wt-% parabens 0.30 wt-% magnesium ascorbyl phosphate 0.50 wt-% hydroquinone 0.5% kojic dipalmitate 0.5% titanium dioxide (ultra fine) 1.0% tocopherol 0.05 wt-% glycerin 0.025 wt-% ascorbyl palmitate 0.01 wt-% sodium chloride 0.003 wt-% ascorbic acid 0.001 wt-% water in order to arrive at 100 wt-%
  • a skin lightening, moisturising, radical scavenging and regenerating body butter for anti-ageing and for after sun treatment of the skin consists of (in weight-%)
  • Vacciniun macrocarpon seed oil 0.001 - 15 wt-% Rubus idaea, seed oil 0.01 - 10 wt-% Soybean phospholipids 2 wt-% C20-C40 fatty alcohols 1.0 wt-%
  • a lightening body care formulation with soothing and moisturising efficacies containing by weight-%
  • cyclopentasiloxane 2.0 wt-% steareth-2 2.0 wt-% steareth-21 1.0 wt-% soybean phospholipids 2.0% octyldodecanol 2.0 wt-% stearic acid 2.0 wt-% cetearyl alcohol 1.5 wt-% peg-30 dipolyhydroxystearate 1.0 wt-% tocopheryl acetate 1.0 wt-%
  • Hordeum vulgare seed oil 1-10 wt-%
  • the aim of the study was to evaluate the skin lightening efficacy of a cream containing an active ingredient on skin with dark spots (lentigo senile, melasma) in comparison to a placebo cream.
  • the main targets of such alterations are photoexposed body sites such as face, neck and dorsal parts of hands of people over 25 years old.
  • Chroma-Meter CR 300 was used for colorimetry.
  • the colour rating system used to read the results is L* a* b*, wherein L* indicates the luminosity of the colours and a* and b* indicate the axis of two colours: a* red/green colour and b* yellow/blue colour.
  • ITA° value is inversely correlated to the pigmentation intensity: the higher the value, the lighter the colour.
  • the whitening efficacy is shown by increased ITA 0 values and L * values.
  • the study designed in blind, was carried out on 12 women who had at least two age spots located symmetrically on each hand and on each half face. Volunteers were asked not to apply any product on the tested areas (hands or face) for at least 3 hours before performing the measurements. At the beginning of the study two spots, one on the right hand/half face and one on the left hand/half face, were carefully selected and their location reported.
  • a control of uninvolved (nonspotted) healthy skin area on each hand/half face was also selected.
  • T x value after 30 days or after 60 days of treatment
  • T 0 basal value at the beginning of the treatment
  • Figure 1 shows the variations in L* values recorded on spotted skin, wherein the active ingredient is shown as the left column and the placebo as the right column. Time is shown in abscissa and L* value in ordinate.
  • Figure 2 shows the same results for healthy skin.
  • a comparative study of the skin moisturization potential of RED ALFA lingonberry seed oil at 5 wt-% was carried out via measurements of the skin electrical capacitance (corneometry). This was a clinical double-blind randomized comparative placebo-controlled study, wherein a test cream containing 5% red alfa lingonberry seed oil was compared to a base cream (placebo).
  • Corneometry measurements were made with the Corneometer CM 820, The measurement area was 49 mm 2 . Twenty measurements were made on each area.
  • the readings indicated the degree of moisture on the skin surface based on variations in electric capacitance.
  • the apparatus scale is arbitrary, i.e., greater reading values indicate greater moisture.
  • the volunteers stayed in rest for 30 minutes, in an acclimatized room with temperature 20 ⁇ 2 °C and relative humidity 50 ⁇ 5 %.
  • Symmetrical areas of 25 cm 2 of the skin on the anterior area of the legs or arms were chosen at random and demarcated: an area for the application of the test product (base cream + 5 wt-% red alfa lingonberry seed oil), an area for the application of the placebo (base cream, i.e. the same formula without the active ingredient RED ALFA lingonberry seed oil) and an area to be kept as a negative control (i.e. an area without product).
  • test product base cream + 5 wt-% RED ALFA lingonberry seed oil
  • placebo base cream only
  • Figure 5 shows the increase in the capacitance of skin, indicating increases in skin moisture after the treatment. Time after application is shown in abscissa and the increase in capacitance compared to baseline, after treatment in ordinate.
  • the leftmost column represents the results for the areas treated with base cream containing 5 % of RED ALFA lingonberry seed oil, the middle column represents the results for the areas treated with base cream only, and the right-most column the results for the untreated areas.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)

Abstract

La présente invention concerne l'emploi d'une préparation comprenant au moins un triglycéride d'au moins un acide aminé insaturé dans la fabrication d'un produit destiné à l'éclaircissement de la peau. La présente invention concerne également une préparation de soins de la peau qui comprend un adjuvant de qualité dermatologique, ainsi qu'une huile de graine pure extraite d'une plante sélectionnée au sein du groupe constitué par Rubus, Vaccinium, Oxycoccus, Fragaria, Hipphophae, Echium, Hordeum, Avena, ou un mélange de ces huiles, et comprenant au moins un triglycéride d'au moins un acide gras insaturé, à l'exception de l'huile des graines de Rubus chamaemorus. En outre, la présente invention concerne une méthode d'éclaircissement de la peau à des fins cosmétiques.
PCT/FI2006/000139 2005-04-29 2006-04-28 Préparations pour l'éclaircissement de la peau WO2006117430A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ES06743508.1T ES2437035T3 (es) 2005-04-29 2006-04-28 Composiciones de aclarado cutáneo
EP06743508.1A EP1909918B1 (fr) 2005-04-29 2006-04-28 Préparations pour l'éclaircissement de la peau

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20050453A FI20050453A0 (fi) 2005-04-29 2005-04-29 Ihonhoitokoostumus
FI20050453 2005-04-29

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WO2006117430A1 true WO2006117430A1 (fr) 2006-11-09

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ES (1) ES2437035T3 (fr)
FI (1) FI20050453A0 (fr)
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100905388B1 (ko) 2008-12-26 2009-07-01 충청남도 엘라직산을 유효성분으로 포함하는 피부 미백활성을 갖는 재배딸기류의 잎 추출물
EP2749288A2 (fr) * 2012-12-28 2014-07-02 Aromtech Ltd Capsule et composition comprenant de l'huile de graines
EP3566751A1 (fr) 2012-02-21 2019-11-13 Lumene Oy Compositions cosmétiques contenant une préparation de culture cellulaire de mûres arctiques

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02108613A (ja) * 1988-10-19 1990-04-20 Kurooda Japan Kk 化粧料組成物
FR2720901A1 (fr) * 1994-06-08 1995-12-15 Germandre Laboratoire Perfectionnements apportés aux compléments nutritifs en utilisant des tourteaux de fruits, compositions et procédés.
WO1997046219A1 (fr) * 1996-06-03 1997-12-11 Croda International Plc Compositions et leurs emplois
WO1999055352A1 (fr) * 1998-04-29 1999-11-04 Avon Products, Inc. Composition d'eclaircissement de la peau
EP0992236A1 (fr) 1997-06-10 2000-04-12 Sunstar Inc. Produit cosmetique eclaircissant la peau
US20020022006A1 (en) * 1999-03-12 2002-02-21 Myung Woo Jung Tooth paste composition containing rose-seed oil
US20020168430A1 (en) * 2000-05-12 2002-11-14 Tim Heeg Cranberry seed oil, cranberry seed flour and a method for making
DE10163786A1 (de) * 2001-12-22 2003-07-03 Beiersdorf Ag Kosmetische und/oder dermatologische Wirkstoffkombination
JP2004123563A (ja) * 2002-09-30 2004-04-22 Iskra Ind Co Ltd 沙棘から得られた果実油と他の生薬の抽出成分を含む化粧料
WO2004060364A1 (fr) * 2002-12-27 2004-07-22 Daiichi Pharmaceutical Co., Ltd. Composition eclaircissant la peau
EP1454622A1 (fr) * 2003-03-04 2004-09-08 Johnson & Johnson Consumer Companies, Inc. Composition d'hydratation pour la peau
WO2004082642A1 (fr) * 2003-03-17 2004-09-30 Oy Psorioil Ltd Produit de soin pour la peau contenant des acides gras de resine liquide et des huiles vegetales pour peau seche et desquamee et traitement du psoriasis, de la dermatite et des eczemas
US20050048020A1 (en) * 2003-07-07 2005-03-03 Wille John J. Novel topical delivery system for plant derived anti-irritants

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02108613A (ja) * 1988-10-19 1990-04-20 Kurooda Japan Kk 化粧料組成物
FR2720901A1 (fr) * 1994-06-08 1995-12-15 Germandre Laboratoire Perfectionnements apportés aux compléments nutritifs en utilisant des tourteaux de fruits, compositions et procédés.
WO1997046219A1 (fr) * 1996-06-03 1997-12-11 Croda International Plc Compositions et leurs emplois
EP0992236A1 (fr) 1997-06-10 2000-04-12 Sunstar Inc. Produit cosmetique eclaircissant la peau
WO1999055352A1 (fr) * 1998-04-29 1999-11-04 Avon Products, Inc. Composition d'eclaircissement de la peau
US20020022006A1 (en) * 1999-03-12 2002-02-21 Myung Woo Jung Tooth paste composition containing rose-seed oil
US20020168430A1 (en) * 2000-05-12 2002-11-14 Tim Heeg Cranberry seed oil, cranberry seed flour and a method for making
DE10163786A1 (de) * 2001-12-22 2003-07-03 Beiersdorf Ag Kosmetische und/oder dermatologische Wirkstoffkombination
JP2004123563A (ja) * 2002-09-30 2004-04-22 Iskra Ind Co Ltd 沙棘から得られた果実油と他の生薬の抽出成分を含む化粧料
WO2004060364A1 (fr) * 2002-12-27 2004-07-22 Daiichi Pharmaceutical Co., Ltd. Composition eclaircissant la peau
EP1586315A1 (fr) * 2002-12-27 2005-10-19 Daiichi Pharmaceutical Co., Ltd. Composition eclaircissant la peau
EP1454622A1 (fr) * 2003-03-04 2004-09-08 Johnson & Johnson Consumer Companies, Inc. Composition d'hydratation pour la peau
WO2004082642A1 (fr) * 2003-03-17 2004-09-30 Oy Psorioil Ltd Produit de soin pour la peau contenant des acides gras de resine liquide et des huiles vegetales pour peau seche et desquamee et traitement du psoriasis, de la dermatite et des eczemas
US20050048020A1 (en) * 2003-07-07 2005-03-03 Wille John J. Novel topical delivery system for plant derived anti-irritants

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 014, no. 314 (C - 0737) 5 July 1990 (1990-07-05) *
PATENT ABSTRACTS OF JAPAN vol. 2003, no. 12 5 December 2003 (2003-12-05) *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100905388B1 (ko) 2008-12-26 2009-07-01 충청남도 엘라직산을 유효성분으로 포함하는 피부 미백활성을 갖는 재배딸기류의 잎 추출물
EP3566751A1 (fr) 2012-02-21 2019-11-13 Lumene Oy Compositions cosmétiques contenant une préparation de culture cellulaire de mûres arctiques
EP2749288A2 (fr) * 2012-12-28 2014-07-02 Aromtech Ltd Capsule et composition comprenant de l'huile de graines
EP2749288A3 (fr) * 2012-12-28 2014-07-23 Aromtech Ltd Capsule et composition comprenant de l'huile de graines

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