WO2006093651A3 - Procedes et ensemble pour diagnostiquer les maladies transmises par les tiques - Google Patents

Procedes et ensemble pour diagnostiquer les maladies transmises par les tiques Download PDF

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Publication number
WO2006093651A3
WO2006093651A3 PCT/US2006/004595 US2006004595W WO2006093651A3 WO 2006093651 A3 WO2006093651 A3 WO 2006093651A3 US 2006004595 W US2006004595 W US 2006004595W WO 2006093651 A3 WO2006093651 A3 WO 2006093651A3
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WO
WIPO (PCT)
Prior art keywords
peptides
tick borne
kit
methods
elisa
Prior art date
Application number
PCT/US2006/004595
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English (en)
Other versions
WO2006093651A2 (fr
Inventor
Aristo Vojdani
Original Assignee
Immunosciences Lab Inc
Aristo Vojdani
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Immunosciences Lab Inc, Aristo Vojdani filed Critical Immunosciences Lab Inc
Publication of WO2006093651A2 publication Critical patent/WO2006093651A2/fr
Publication of WO2006093651A3 publication Critical patent/WO2006093651A3/fr

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56905—Protozoa
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/20—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/29—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Richettsiales (o)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G01N2333/43552—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from insects
    • G01N2333/43556—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from insects from ticks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/42—Poisoning, e.g. from bites or stings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)

Abstract

On a appliqué ELISA, Western Blot et ELISA à base de peptides à des échantillons cliniques provenant de patients souffrant de symptômes cliniques de maladies transmises par les tiques, y compris la maladie de Lyme. On a utilisé des peptides provenant de différents composants de Borrelia pendant des cycles différents, y compris les peptides provenant de la protéine de surface externe, les antigènes associés à la fonction de leucocytes, les antigènes immunodominants, les protéines principales variables et les peptides provenant des protéines de liaison de décorine des sous-espèces Borrelia (B. sensu stricto, B. afzelii, B. garinii). On a également mesuré des anticorps dirigés contre des peptides déterminés provenant de Babesia et d'Ehrlichia.
PCT/US2006/004595 2005-02-25 2006-02-08 Procedes et ensemble pour diagnostiquer les maladies transmises par les tiques WO2006093651A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/066,399 2005-02-25
US11/066,399 US7390626B2 (en) 2005-02-25 2005-02-25 Methods and kit for diagnosing tick borne illnesses

Publications (2)

Publication Number Publication Date
WO2006093651A2 WO2006093651A2 (fr) 2006-09-08
WO2006093651A3 true WO2006093651A3 (fr) 2007-02-01

Family

ID=36687981

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/004595 WO2006093651A2 (fr) 2005-02-25 2006-02-08 Procedes et ensemble pour diagnostiquer les maladies transmises par les tiques

Country Status (2)

Country Link
US (1) US7390626B2 (fr)
WO (1) WO2006093651A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8257938B2 (en) * 2009-02-27 2012-09-04 Medical Diagnostic Laboratories, Llc Hemolysin and its protein fragments in sero-detection of Anaplasma phagocytophilum
CA2781110C (fr) * 2009-11-17 2018-07-31 Abaxis, Inc. Peptides et procedes pour la detection d'anticorps contre la maladie de lyme
WO2011068844A1 (fr) * 2009-12-01 2011-06-09 Temple Douglas Test diagnostique d'antigène bactérien de borrelia burgdorferi utilisant des particules de capture contenant un appât polymère
WO2011090747A2 (fr) 2009-12-29 2011-07-28 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Système et procédé pour fournir évaluation du risque de rencontrer des tiques
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
CN103229055A (zh) 2010-09-27 2013-07-31 康奈尔大学 莱姆病的诊断方法
DE112011100879A5 (de) * 2011-08-30 2013-11-14 Jacobs University Bremen Ggmbh Gen codiert für ein MHC-Klasse-I-Molekül, Plasmid, Expressionssystem, Protein, Multimer, Reagenz und Kit zum Analysieren einer T-Zellen-Frequenz
US8758772B2 (en) 2011-11-04 2014-06-24 Abaxis, Inc. Peptides and methods for the detection of lyme disease antibodies
US9133525B2 (en) 2012-01-26 2015-09-15 Luc Montagnier Detection of DNA sequences as risk factors for HIV infection
WO2013116668A2 (fr) * 2012-02-01 2013-08-08 Biopeptides Corp Peptides diagnostiques pour la maladie de lyme
PT106942B (pt) * 2013-05-15 2020-09-10 STAB VIDA, Investigação e Serviços em Ciências Biológicas, Lda Biochip (1) e bouquet de 16 antigénios (2) para a deteção da doença de lyme aguda e crónica
US9580758B2 (en) 2013-11-12 2017-02-28 Luc Montagnier System and method for the detection and treatment of infection by a microbial agent associated with HIV infection
US9194870B2 (en) 2014-01-21 2015-11-24 Abaxis, Inc. Peptides, devices, and methods for the detection of Anaplasma antibodies
EP3252470B1 (fr) * 2016-06-03 2020-07-29 Te?ted Oy Procédé et support solide pour la détection de microbes transmis par les tiques dans un échantillon biologique
BR102017002668A2 (pt) * 2017-02-09 2018-10-30 Biotick Pesquisa E Desenvolvimento Tecnologico Ltda peptídeo híbrido, conjunto de peptídeos híbridos, composição, usos do peptídeo híbrido, método de induzir resposta imune e kits
CN109897830B (zh) * 2019-03-25 2022-08-19 新疆农业大学 马泰勒虫ema1单克隆抗体及其应用
US20210215715A1 (en) * 2020-01-10 2021-07-15 Quidel Corporation Test strip with structured substrate for multiplex lateral flow assay for disease diagnostics
CN112725488B (zh) * 2021-02-04 2023-03-24 吉林大学 埃利希氏体病和莱姆病双重荧光定量pcr引物及试剂盒

Citations (2)

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Publication number Priority date Publication date Assignee Title
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Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
US20020064535A1 (en) * 1997-03-21 2002-05-30 Steven G. Reed Compounds and methods for the diagnosis and treatment of ehrlichia infection
WO2001020325A1 (fr) * 1999-09-16 2001-03-22 Immunetics, Inc. Dosages immunologiques de membrane permettant de detecter plusieurs maladies transmises par des tiques

Non-Patent Citations (7)

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Title
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Publication number Publication date
US7390626B2 (en) 2008-06-24
US20060194267A1 (en) 2006-08-31
WO2006093651A2 (fr) 2006-09-08

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