WO2006092074A1 - Menthane carboxamide derivatives having cooling properties - Google Patents

Menthane carboxamide derivatives having cooling properties Download PDF

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Publication number
WO2006092074A1
WO2006092074A1 PCT/CH2006/000116 CH2006000116W WO2006092074A1 WO 2006092074 A1 WO2006092074 A1 WO 2006092074A1 CH 2006000116 W CH2006000116 W CH 2006000116W WO 2006092074 A1 WO2006092074 A1 WO 2006092074A1
Authority
WO
WIPO (PCT)
Prior art keywords
cooling
compound
compounds
cooling properties
carboxamide derivatives
Prior art date
Application number
PCT/CH2006/000116
Other languages
English (en)
French (fr)
Inventor
Lucienne Cole
Stefan Michael Furrer
Christophe Galopin
Pablo Victor Krawec
Adam Masur
Jay Patrick Slack
Original Assignee
Givaudan Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Givaudan Sa filed Critical Givaudan Sa
Priority to EP06705356A priority Critical patent/EP1853565B1/en
Priority to BRPI0607407-3A priority patent/BRPI0607407A2/pt
Priority to JP2007557307A priority patent/JP2008531606A/ja
Priority to CA002597415A priority patent/CA2597415A1/en
Priority to MX2007010040A priority patent/MX2007010040A/es
Priority to DE602006017038T priority patent/DE602006017038D1/de
Priority to CN200680006684XA priority patent/CN101133030B/zh
Priority to AT06705356T priority patent/ATE482199T1/de
Priority to US11/884,479 priority patent/US7868004B2/en
Publication of WO2006092074A1 publication Critical patent/WO2006092074A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/24—Thermal properties
    • A61K2800/244—Endothermic; Cooling; Cooling sensation

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Seasonings (AREA)
PCT/CH2006/000116 2005-03-01 2006-02-23 Menthane carboxamide derivatives having cooling properties WO2006092074A1 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
EP06705356A EP1853565B1 (en) 2005-03-01 2006-02-23 Menthane carboxamide derivatives having cooling properties
BRPI0607407-3A BRPI0607407A2 (pt) 2005-03-01 2006-02-23 derivados de mentano carboxamida tendo propriedades de refrescáncia
JP2007557307A JP2008531606A (ja) 2005-03-01 2006-02-23 ヘテロ環化合物
CA002597415A CA2597415A1 (en) 2005-03-01 2006-02-23 Menthane carboxamide derivatives having cooling properties
MX2007010040A MX2007010040A (es) 2005-03-01 2006-02-23 Derivados de mentan carboxamida que tienen propiedades refrescantes.
DE602006017038T DE602006017038D1 (de) 2005-03-01 2006-02-23 Menthancarbonsäureamidderivate mit kühlenden eigenschaften
CN200680006684XA CN101133030B (zh) 2005-03-01 2006-02-23 具有清凉性质的薄荷烷甲酰胺衍生物
AT06705356T ATE482199T1 (de) 2005-03-01 2006-02-23 Menthancarbonsäureamidderivate mit kühlenden eigenschaften
US11/884,479 US7868004B2 (en) 2005-03-01 2006-02-23 Menthane carboxamide derivatives having cooling properties

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65756205P 2005-03-01 2005-03-01
US60/657,562 2005-03-01

Publications (1)

Publication Number Publication Date
WO2006092074A1 true WO2006092074A1 (en) 2006-09-08

Family

ID=36127379

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CH2006/000116 WO2006092074A1 (en) 2005-03-01 2006-02-23 Menthane carboxamide derivatives having cooling properties

Country Status (12)

Country Link
US (1) US7868004B2 (US07868004-20110111-C00007.png)
EP (1) EP1853565B1 (US07868004-20110111-C00007.png)
JP (1) JP2008531606A (US07868004-20110111-C00007.png)
KR (1) KR20070107083A (US07868004-20110111-C00007.png)
CN (1) CN101133030B (US07868004-20110111-C00007.png)
AT (1) ATE482199T1 (US07868004-20110111-C00007.png)
BR (1) BRPI0607407A2 (US07868004-20110111-C00007.png)
CA (1) CA2597415A1 (US07868004-20110111-C00007.png)
DE (1) DE602006017038D1 (US07868004-20110111-C00007.png)
ES (1) ES2352563T3 (US07868004-20110111-C00007.png)
MX (1) MX2007010040A (US07868004-20110111-C00007.png)
WO (1) WO2006092074A1 (US07868004-20110111-C00007.png)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007048265A1 (en) * 2005-10-25 2007-05-03 Givaudan Sa Organic compounds
USRE44339E1 (en) 2003-11-21 2013-07-02 Givaudan S.A. N-substituted P-menthane carboxamides
WO2012120099A3 (en) * 2011-03-08 2013-08-01 B.R.A.I.N. Biotechnology Research And Information Network Ag Small molecule modulators of the cold and menthol receptor trpm8
US10299999B2 (en) 2011-02-23 2019-05-28 Givaudan S.A. Flavour composition comprising menthol and menthane carboxamides

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0721140A2 (pt) * 2006-12-20 2014-04-01 Givaudan Nederland Services Bv P-mentano-3-carboxamida n-substituída e usos da mesma.
WO2009076792A1 (en) * 2007-12-19 2009-06-25 Givaudan Sa Cooling compounds
WO2009089641A1 (en) * 2008-01-17 2009-07-23 Givaudan Sa Benzimidazole derivatives and their use as cooling agents
GB0902849D0 (en) * 2009-02-19 2009-04-08 Givaudan Sa Organic compounds
US20150307447A1 (en) 2014-04-23 2015-10-29 The Procter & Gamble Company Compositions for deposition on biological surfaces

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1351761A (en) * 1971-02-04 1974-05-01 Wilkinson Sword Ltd Substituted p-menthane carboxamides and compositions containing them
WO2005002582A2 (en) * 2003-07-02 2005-01-13 Genentech, Inc. Trp-p8 active compounds and therapeutic treatment methods
WO2005020897A2 (en) * 2003-08-22 2005-03-10 Dendreon Corporation Compositions and methods for the treatment of disease associated with trp-p8 expression

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5918309A (en) * 1997-10-14 1999-07-06 Second Chance Body Armor, Inc. Blunt force resistant structure for a protective garment
CN1300095C (zh) 2002-10-28 2007-02-14 吉万奥丹股份有限公司 清凉剂溶液及含有其的组合物
JP4786544B2 (ja) 2003-11-21 2011-10-05 ジボダン エス エー Ｎ置換ｐ−メンタンカルボキサミド類
GB0425661D0 (en) 2004-11-23 2004-12-22 Givaudan Sa Organic compounds
US8673198B2 (en) * 2006-02-18 2014-03-18 Honeywell International Inc Method of making improved ballistic products

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1351761A (en) * 1971-02-04 1974-05-01 Wilkinson Sword Ltd Substituted p-menthane carboxamides and compositions containing them
WO2005002582A2 (en) * 2003-07-02 2005-01-13 Genentech, Inc. Trp-p8 active compounds and therapeutic treatment methods
WO2005020897A2 (en) * 2003-08-22 2005-03-10 Dendreon Corporation Compositions and methods for the treatment of disease associated with trp-p8 expression

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE44339E1 (en) 2003-11-21 2013-07-02 Givaudan S.A. N-substituted P-menthane carboxamides
WO2007048265A1 (en) * 2005-10-25 2007-05-03 Givaudan Sa Organic compounds
US8263046B2 (en) 2005-10-25 2012-09-11 Givaudan S.A. N-phenyl-N-pyridinyl-benzamides and benzenesulfonomides having cooling properties
US10299999B2 (en) 2011-02-23 2019-05-28 Givaudan S.A. Flavour composition comprising menthol and menthane carboxamides
WO2012120099A3 (en) * 2011-03-08 2013-08-01 B.R.A.I.N. Biotechnology Research And Information Network Ag Small molecule modulators of the cold and menthol receptor trpm8
US9585865B2 (en) 2011-03-08 2017-03-07 B.R.A.I.N. Biotechnology Research And Information Network Ag Small molecule modulators of the cold and menthol receptor TRPM8

Also Published As

Publication number Publication date
DE602006017038D1 (de) 2010-11-04
BRPI0607407A2 (pt) 2009-09-01
CN101133030B (zh) 2010-07-28
US20080305051A1 (en) 2008-12-11
MX2007010040A (es) 2007-09-21
ES2352563T3 (es) 2011-02-21
CA2597415A1 (en) 2006-09-08
US7868004B2 (en) 2011-01-11
ATE482199T1 (de) 2010-10-15
JP2008531606A (ja) 2008-08-14
KR20070107083A (ko) 2007-11-06
CN101133030A (zh) 2008-02-27
EP1853565A1 (en) 2007-11-14
EP1853565B1 (en) 2010-09-22

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