WO2006079797A3 - Dispositif permettant de mesurer la concentration d'un melange a analyser - Google Patents

Dispositif permettant de mesurer la concentration d'un melange a analyser Download PDF

Info

Publication number
WO2006079797A3
WO2006079797A3 PCT/GB2006/000243 GB2006000243W WO2006079797A3 WO 2006079797 A3 WO2006079797 A3 WO 2006079797A3 GB 2006000243 W GB2006000243 W GB 2006000243W WO 2006079797 A3 WO2006079797 A3 WO 2006079797A3
Authority
WO
WIPO (PCT)
Prior art keywords
measurement
waveguide
outputting
analyte
body region
Prior art date
Application number
PCT/GB2006/000243
Other languages
English (en)
Other versions
WO2006079797A2 (fr
Inventor
Dawood Parker
John Edwin Enderby
Original Assignee
Melys Diagnostics Ltd
Dawood Parker
John Edwin Enderby
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melys Diagnostics Ltd, Dawood Parker, John Edwin Enderby filed Critical Melys Diagnostics Ltd
Publication of WO2006079797A2 publication Critical patent/WO2006079797A2/fr
Publication of WO2006079797A3 publication Critical patent/WO2006079797A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/359—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light

Abstract

Cette invention concerne un dispositif conçu pour mesurer un mélange à analyser, tel que du glucose, lequel dispositif infrarouge dans deux directions opposées, un guide d'onde ATR (4), présentant une surface pour former une interface avec une zone corporelle, telle que la peau, des collimateurs de guides d'onde creux (2) et (5), et des détecteurs (3) et (6) permettant d'effectuer des mesures, et des bandes de longueurs d'onde de référence émettant une absorbance optique d pour la bande de mesure et une absorbance optique c pour la bande de référence, et produisant une sortie chronologique de la concentration g du mélange à analyser, laquelle sortie est calculée avec A et b/a qui sont des constantes pour un ensemble donné de conditions d'utilisation, et b et a correspondent aux mesures d et c respectivement; ces mesures étant déterminées avec de l'eau plutôt que dans une situation où la zone corporelle est en contact avec la surface du guide d'onde optique. Le collimateur (5) et le détecteur (6) visualise le guide d'onde (4) à un angle réglable a. L'effet de la température sur les mesures est compensé par une lecture obtenue à partir d'un thermomètre (8). Une valeur finale pour g est obtenue par application d'un algorithme prédictif à des mesures prises à des intervalles temporels.
PCT/GB2006/000243 2005-01-28 2006-01-25 Dispositif permettant de mesurer la concentration d'un melange a analyser WO2006079797A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0501826.2A GB0501826D0 (en) 2005-01-28 2005-01-28 Apparatus for measurement of analyte concentration
GB0501826.2 2005-01-28

Publications (2)

Publication Number Publication Date
WO2006079797A2 WO2006079797A2 (fr) 2006-08-03
WO2006079797A3 true WO2006079797A3 (fr) 2006-10-05

Family

ID=34307635

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2006/000243 WO2006079797A2 (fr) 2005-01-28 2006-01-25 Dispositif permettant de mesurer la concentration d'un melange a analyser

Country Status (2)

Country Link
GB (1) GB0501826D0 (fr)
WO (1) WO2006079797A2 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8647489B2 (en) 2005-09-30 2014-02-11 Bayer Healthcare Llc Gated voltammetry devices
US8877035B2 (en) 2005-07-20 2014-11-04 Bayer Healthcare Llc Gated amperometry methods
US9005527B2 (en) 2006-10-24 2015-04-14 Bayer Healthcare Llc Transient decay amperometry biosensors
US9410917B2 (en) 2004-02-06 2016-08-09 Ascensia Diabetes Care Holdings Ag Method of using a biosensor

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007100651A1 (fr) 2006-02-27 2007-09-07 Bayer Healthcare Llc Détermination d'analyte ajustée à une température pour des systèmes biocapteurs
US7966859B2 (en) 2006-05-03 2011-06-28 Bayer Healthcare Llc Underfill detection system for a biosensor
CA2708038A1 (fr) 2007-12-10 2009-09-03 Bayer Healthcare Llc Compensation sur la base de la pente
WO2009076302A1 (fr) 2007-12-10 2009-06-18 Bayer Healthcare Llc Marqueurs de contrôle pour la détection automatique d'une solution de contrôle et procédés d'utilisation
EP2373984B1 (fr) 2008-12-08 2022-11-30 Ascensia Diabetes Care Holdings AG Ajustement de signal d'un biocapteur
EP2259048A1 (fr) 2009-06-03 2010-12-08 Koninklijke Philips Electronics N.V. Mesure de la réflectance à l'aide d'un guide d'onde pour coupler la lumière à un volume d'échantillon plus élevé
KR101685234B1 (ko) 2009-11-10 2016-12-09 바이엘 헬스케어 엘엘씨 바이오센서용 언더필 인식 시스템
CA2793878C (fr) 2010-03-22 2018-09-11 Bayer Healthcare Llc Compensation residuelle pour biocapteur
JP5856155B2 (ja) 2010-06-07 2016-02-09 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅＬＬＣ バイオセンサのための充填不足管理システム
EP2577302B8 (fr) 2010-06-07 2016-10-26 Ascensia Diabetes Care Holdings AG Procédé de compensation de la pente par des signaux de sortie secondaires
JP6091500B2 (ja) 2011-06-07 2017-03-08 メジャメント スペシャリティーズ， インコーポレイテッド 流体検出のための光検出装置、およびそのための方法
MX350696B (es) 2011-09-21 2017-09-14 Ascensia Diabetes Care Holdings Ag Biosensor con compensación de error.
WO2015030832A1 (fr) * 2013-08-31 2015-03-05 Pandata Research Llc Module optoélectronique intégré pour mesures physiologiques et méthodes d'utilisation dudit module
WO2015156777A1 (fr) * 2014-04-08 2015-10-15 Pandata Research Llc Système de mesure optique ayant un élément de réflexion interne intégré et un détecteur de réseau
WO2015156778A1 (fr) * 2014-04-08 2015-10-15 Pandata Research Llc Système de mesure optique ayant un élément de réflexion interne intégré et une pluralité de détecteurs réseau
WO2015167417A1 (fr) * 2014-04-08 2015-11-05 Pandata Research Llc Système de mesure optique présentant un détecteur de réseau et élément de réflexion interne intégré
US10806385B2 (en) 2015-01-21 2020-10-20 National Institutes For Quantum And Radiological Science And Technology Device for measuring concentration of substance in blood, and method for measuring concentration of substance in blood
US10983064B2 (en) * 2015-11-23 2021-04-20 Roche Diabetes Care, Inc. Method and apparatus for determining the concentration of an analyte in a body fluid
WO2018122319A1 (fr) * 2016-12-30 2018-07-05 Swiss Spectral Ag Dispositif et procédé de détermination non-invasive d'analytes
ES2774983B2 (es) 2019-01-22 2021-06-10 Univ Sevilla Dispositivo portable y metodo para la estimacion no invasiva del nivel de glucosa en sangre
JP7438774B2 (ja) * 2020-02-05 2024-02-27 アズビル株式会社 測定装置
WO2023060953A1 (fr) * 2021-10-12 2023-04-20 深圳硅基传感科技有限公司 Capteur et procédé d'obtention de concentrations d'analytes avec prise en compte de compensation de températures
CN114878492A (zh) * 2022-06-02 2022-08-09 西北核技术研究所 一种基于温度敏感因子的超光谱光源扫描区间选择方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0160768A1 (fr) * 1984-05-04 1985-11-13 Kurabo Industries Ltd. Dispositif spectrophotométrique pour la détermination, par voie non-invasive, de glucose dans les tissus vivants
WO1992017765A1 (fr) * 1991-03-28 1992-10-15 Johnson & Johnson Professional Products Limited Procede et appareil de controle de la concentration de glucose
US5553613A (en) * 1994-08-17 1996-09-10 Pfizer Inc. Non invasive blood analyte sensor
WO2001079818A2 (fr) * 2000-04-12 2001-10-25 Medoptix, Inc. Systeme (ii) de mesure de glucose faisant intervenir la spectroscopie infrarouge par reflexion totale attenuee (atr)
US20030023152A1 (en) * 2001-04-11 2003-01-30 Abbink Russell E. System for non-invasive measurement of glucose in humans
US20030031597A1 (en) * 2001-08-03 2003-02-13 Waseda University Apparatus for measuring glucose concentration
WO2004091403A1 (fr) * 2003-04-15 2004-10-28 Optiscan Biomedical Corporation Element d'echantillonnage dote d'un materiau barriere

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0160768A1 (fr) * 1984-05-04 1985-11-13 Kurabo Industries Ltd. Dispositif spectrophotométrique pour la détermination, par voie non-invasive, de glucose dans les tissus vivants
WO1992017765A1 (fr) * 1991-03-28 1992-10-15 Johnson & Johnson Professional Products Limited Procede et appareil de controle de la concentration de glucose
US5553613A (en) * 1994-08-17 1996-09-10 Pfizer Inc. Non invasive blood analyte sensor
WO2001079818A2 (fr) * 2000-04-12 2001-10-25 Medoptix, Inc. Systeme (ii) de mesure de glucose faisant intervenir la spectroscopie infrarouge par reflexion totale attenuee (atr)
US20030023152A1 (en) * 2001-04-11 2003-01-30 Abbink Russell E. System for non-invasive measurement of glucose in humans
US20030031597A1 (en) * 2001-08-03 2003-02-13 Waseda University Apparatus for measuring glucose concentration
WO2004091403A1 (fr) * 2003-04-15 2004-10-28 Optiscan Biomedical Corporation Element d'echantillonnage dote d'un materiau barriere

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KEN-ICHIRO KAJIWARA: "SPECTROSCOPIC QUANTITATIVE ANALYSIS OF BLOOD GLUCOSE BY FOURIER TRANSFORM INFRARED SPECTROSCOPY WITH AN ATTENUATED TOTAL REFLECTIONPRISM", MEDICAL PROGRESS THROUGH TECHNOLOGY, SPRINGER VERLAG. BERLIN, DE, vol. 18, no. 3, January 1992 (1992-01-01), pages 181 - 189, XP000331119, ISSN: 0047-6552 *
SIMHI R ET AL: "Blood diagnostics using fiberoptic evanescent wave spectroscopy and neural networks analysis", SENSORS AND ACTUATORS B, ELSEVIER SEQUOIA S.A., LAUSANNE, CH, vol. 42, no. 3, August 1997 (1997-08-01), pages 157 - 161, XP004100260, ISSN: 0925-4005 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9410917B2 (en) 2004-02-06 2016-08-09 Ascensia Diabetes Care Holdings Ag Method of using a biosensor
US8877035B2 (en) 2005-07-20 2014-11-04 Bayer Healthcare Llc Gated amperometry methods
US8647489B2 (en) 2005-09-30 2014-02-11 Bayer Healthcare Llc Gated voltammetry devices
US9110013B2 (en) 2005-09-30 2015-08-18 Bayer Healthcare Llc Gated voltammetry methods
US9005527B2 (en) 2006-10-24 2015-04-14 Bayer Healthcare Llc Transient decay amperometry biosensors

Also Published As

Publication number Publication date
GB0501826D0 (en) 2005-03-09
WO2006079797A2 (fr) 2006-08-03

Similar Documents

Publication Publication Date Title
WO2006079797A3 (fr) Dispositif permettant de mesurer la concentration d'un melange a analyser
US11653862B2 (en) Non-invasive optical physiological differential pathlength sensor
JP7423622B2 (ja) 物質を分析するための装置および方法
Kasemsumran et al. Improvement of partial least squares models for in vitro and in vivo glucose quantifications by using near-infrared spectroscopy and searching combination moving window partial least squares
US20080269580A1 (en) System for Non-Invasive Measurement of Bloold Glucose Concentration
TWI324686B (en) Noninvasive measurement of glucose through the optical properties of tissue
Tenhunen et al. Non-invasive glucose measurement based on selective near infrared absorption; requirements on instrumentation and spectral range
WO1998040724A1 (fr) Spectrometrie sous-cutanee par gradient thermique
KR20040086806A (ko) 특정성분농도의 측정방법 및 측정장치
WO2006040841A1 (fr) Instrument de mesure non invasive de la glycemie
RU2010135518A (ru) Способ неинвазивного оптического определения температуры среды
US9332936B2 (en) Concentration determination apparatus and concentration determination method for detecting an absorbance of living body tissue based on a light intensity and measuring a concentration of a measured component contained in living body tissue
JPH1033512A (ja) 無侵襲生化学計測装置
CN102207458A (zh) 基于光纤光栅的近红外吸收浓度传感器信号解调方法
JPH10108857A (ja) 生化学計測装置
WO2014097965A1 (fr) Dispositif de mesure de la saturation en oxygène et procédé de calcul de la saturation en oxygène
JP4052461B2 (ja) 血糖値の非侵襲測定装置
JP2004317381A (ja) 青果物の非破壊糖度測定装置
Li et al. Improved extended multiplicative scatter correction algorithm applied in blood glucose noninvasive measurement with FT-IR spectroscopy
JP2004219322A (ja) 非破壊分光測定器
Zhang et al. Reducing the spectral nonlinearity error caused by varying integration time
KR100883153B1 (ko) 혈당치의 비침습 측정 장치
JP2008528983A5 (fr)
US10408755B2 (en) Optical device and method for determining an optical property of specimen
KR102540285B1 (ko) 비침습 혈당 측정 시스템

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase

Ref document number: 06701038

Country of ref document: EP

Kind code of ref document: A2

WWW Wipo information: withdrawn in national office

Ref document number: 6701038

Country of ref document: EP