WO2006050737A1 - Polypeptides having antimicrobial activity and polynucleotides encoding same - Google Patents

Polypeptides having antimicrobial activity and polynucleotides encoding same Download PDF

Info

Publication number
WO2006050737A1
WO2006050737A1 PCT/DK2005/000725 DK2005000725W WO2006050737A1 WO 2006050737 A1 WO2006050737 A1 WO 2006050737A1 DK 2005000725 W DK2005000725 W DK 2005000725W WO 2006050737 A1 WO2006050737 A1 WO 2006050737A1
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptide
seq
polynucleotide
nucleotides
amino acids
Prior art date
Application number
PCT/DK2005/000725
Other languages
English (en)
French (fr)
Inventor
Per Holse Mygind
Mogens Trier Hansen
Marianne Vind Soerensen
Dorthe Sandvang
Original Assignee
Novozymes A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP05800951A priority Critical patent/EP1812571A1/en
Priority to CA002587449A priority patent/CA2587449A1/en
Priority to AU2005304115A priority patent/AU2005304115B2/en
Priority to CN2005800464950A priority patent/CN101098964B/zh
Priority to MX2007005520A priority patent/MX2007005520A/es
Priority to BRPI0517477-5A priority patent/BRPI0517477A/pt
Application filed by Novozymes A/S filed Critical Novozymes A/S
Priority to NZ555039A priority patent/NZ555039A/en
Priority to AP2007003991A priority patent/AP2007003991A0/xx
Priority to JP2007540495A priority patent/JP5038144B2/ja
Publication of WO2006050737A1 publication Critical patent/WO2006050737A1/en
Priority to IL183057A priority patent/IL183057A0/en
Priority to NO20072966A priority patent/NO20072966L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
PCT/DK2005/000725 2004-11-12 2005-11-11 Polypeptides having antimicrobial activity and polynucleotides encoding same WO2006050737A1 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
CA002587449A CA2587449A1 (en) 2004-11-12 2005-11-11 Polypeptides having antimicrobial activity and polynucleotides encoding same
AU2005304115A AU2005304115B2 (en) 2004-11-12 2005-11-11 Polypeptides having antimicrobial activity and polynucleotides encoding same
CN2005800464950A CN101098964B (zh) 2004-11-12 2005-11-11 具有抗微生物活性的多肽及编码该多肽的多核苷酸
MX2007005520A MX2007005520A (es) 2004-11-12 2005-11-11 Polipeptidos que tienen actividad antimicrobiana y polinucleotidos que codifican los mismos.
BRPI0517477-5A BRPI0517477A (pt) 2004-11-12 2005-11-11 polipeptìdeo, construção de ácido nucleico, vetor de expressão recombinante, célula hospedeira recombinante, métodos para produzir um polipeptìdeo, um polinucleotìdeo, e uma proteìna, planta, parte de planta ou célula vegetal transgênicas, método para matar ou inibir o crescimento de células microbianas, e, uso de um polipeptìdeo antimicrobiano
EP05800951A EP1812571A1 (en) 2004-11-12 2005-11-11 Polypeptides having antimicrobial activity and polynucleotides encoding same
NZ555039A NZ555039A (en) 2004-11-12 2005-11-11 Polypeptides having antimicrobial activity and polynucleotides encoding same
AP2007003991A AP2007003991A0 (en) 2004-11-12 2005-11-11 Polypeptides having antimicrobial activity and polynucleotides encoding same
JP2007540495A JP5038144B2 (ja) 2004-11-12 2005-11-11 抗菌活性を有するポリペプチド及びそれをコードするポリヌクレオチド
IL183057A IL183057A0 (en) 2004-11-12 2007-05-08 Polypeptides having antimicrobial activity and polynucleotides encoding same
NO20072966A NO20072966L (no) 2004-11-12 2007-06-11 Polypeptider som har antimikrobeaktivitet og polynukleotider som koder for disse

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200401744 2004-11-12
DKPA200401744 2004-11-12

Publications (1)

Publication Number Publication Date
WO2006050737A1 true WO2006050737A1 (en) 2006-05-18

Family

ID=35559391

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2005/000725 WO2006050737A1 (en) 2004-11-12 2005-11-11 Polypeptides having antimicrobial activity and polynucleotides encoding same

Country Status (17)

Country Link
EP (1) EP1812571A1 (zh)
JP (1) JP5038144B2 (zh)
KR (1) KR20070086065A (zh)
CN (1) CN101098964B (zh)
AP (1) AP2007003991A0 (zh)
AR (1) AR051489A1 (zh)
AU (1) AU2005304115B2 (zh)
BR (1) BRPI0517477A (zh)
CA (1) CA2587449A1 (zh)
IL (1) IL183057A0 (zh)
MX (1) MX2007005520A (zh)
NO (1) NO20072966L (zh)
NZ (1) NZ555039A (zh)
RU (1) RU2393224C2 (zh)
TW (1) TW200621284A (zh)
WO (1) WO2006050737A1 (zh)
ZA (1) ZA200704620B (zh)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006097464A1 (en) * 2005-03-16 2006-09-21 Novozymes A/S Recombinant expression of defensins in filamentous fungi
WO2009121828A1 (en) * 2008-04-04 2009-10-08 Novozymes A/S Use of defensins against meningitis
RU2574914C1 (ru) * 2014-12-19 2016-02-10 Элеонора Васильевна Дудникова Способ неинвазивной диагностики хронического гастродуоденита у детей
WO2019016043A1 (en) 2017-07-17 2019-01-24 Adenium Biotech Aps PEPTIDES HAVING ANTIBIOTIC POWERS AGAINST MYCOBACTERIUM TUBERCULOSIS
US11773140B2 (en) 2018-03-29 2023-10-03 Contrafect Corporation Gram-negative lysin-antimicrobial peptide (AMP) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof in human serum

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201016733D0 (en) * 2010-10-05 2010-11-17 Novabiotics Ltd Compounds and their use
RU2449805C1 (ru) 2011-01-27 2012-05-10 Общество С Ограниченной Ответственностью "Гармония" Пептидная фармацевтическая композиция, средство на ее основе для лечения гастродуоденальных заболеваний, вызываемых helicobacter pylori, и способ его использования
US8958867B2 (en) * 2011-08-29 2015-02-17 Infraredx, Inc. Detection of lipid core plaque cap thickness
CN112794892B (zh) * 2019-11-13 2022-09-09 中国科学院动物研究所 一种抗真菌肽突变体及其制备方法和应用
CN112724212B (zh) * 2020-12-30 2022-03-18 山西大学 藜麦蛋白在抗植物病菌中的应用
CN114703166B (zh) * 2022-04-29 2023-07-28 西北农林科技大学 一种假结核耶尔森氏菌抗真菌蛋白、应用及分离纯化方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2695392A1 (fr) * 1992-09-04 1994-03-11 Centre Nat Rech Scient Peptides possédant notamment des propriétés antibactériennes, leur procédé d'obtention, et leurs applications biologiques.
EP1146052A2 (en) * 2000-04-14 2001-10-17 E.I. Du Pont De Nemours And Company Arthropod defensins
WO2002090384A2 (en) * 2001-05-04 2002-11-14 Novozymes A/S Antimicrobial polypeptide from aspergillus niger

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4253799A (en) * 1998-06-12 2000-01-05 Micrologix Biotech, Inc. Cancer therapy with cationic peptides
WO2002009384A2 (en) * 2000-07-25 2002-01-31 Koninklijke Philips Electronics N.V. Gateway for home networks
CN1177055C (zh) * 2001-01-19 2004-11-24 山东大学 家蝇抗菌肽基因及其克隆方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2695392A1 (fr) * 1992-09-04 1994-03-11 Centre Nat Rech Scient Peptides possédant notamment des propriétés antibactériennes, leur procédé d'obtention, et leurs applications biologiques.
EP1146052A2 (en) * 2000-04-14 2001-10-17 E.I. Du Pont De Nemours And Company Arthropod defensins
WO2002090384A2 (en) * 2001-05-04 2002-11-14 Novozymes A/S Antimicrobial polypeptide from aspergillus niger

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BULET PHILIPPE ET AL: "A novel insect defensin mediates the inducible antibacterial activity in larvae of the dragonfly Aeschna cyanea (Paleoptera, Odonata)", EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 209, no. 3, 1992, pages 977 - 984, XP002365744, ISSN: 0014-2956 *
See also references of EP1812571A1 *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006097464A1 (en) * 2005-03-16 2006-09-21 Novozymes A/S Recombinant expression of defensins in filamentous fungi
AU2006224628B2 (en) * 2005-03-16 2012-04-12 Novozymes Adenium Biotech A/S Recombinant expression of defensins in filamentous fungi
WO2009121828A1 (en) * 2008-04-04 2009-10-08 Novozymes A/S Use of defensins against meningitis
RU2574914C1 (ru) * 2014-12-19 2016-02-10 Элеонора Васильевна Дудникова Способ неинвазивной диагностики хронического гастродуоденита у детей
WO2019016043A1 (en) 2017-07-17 2019-01-24 Adenium Biotech Aps PEPTIDES HAVING ANTIBIOTIC POWERS AGAINST MYCOBACTERIUM TUBERCULOSIS
US11034742B2 (en) 2017-07-17 2021-06-15 Linnane Pharma Ab Peptides with antibiotic potential against Mycobacterium tuberculosis
US11773140B2 (en) 2018-03-29 2023-10-03 Contrafect Corporation Gram-negative lysin-antimicrobial peptide (AMP) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof in human serum

Also Published As

Publication number Publication date
ZA200704620B (en) 2008-09-25
RU2393224C2 (ru) 2010-06-27
NZ555039A (en) 2009-09-25
BRPI0517477A (pt) 2008-10-07
AU2005304115B2 (en) 2010-11-18
IL183057A0 (en) 2007-09-20
JP5038144B2 (ja) 2012-10-03
CN101098964A (zh) 2008-01-02
TW200621284A (en) 2006-07-01
EP1812571A1 (en) 2007-08-01
RU2007121712A (ru) 2008-12-20
MX2007005520A (es) 2007-07-09
JP2008519585A (ja) 2008-06-12
AU2005304115A1 (en) 2006-05-18
CN101098964B (zh) 2013-03-20
KR20070086065A (ko) 2007-08-27
AP2007003991A0 (en) 2007-06-30
AR051489A1 (es) 2007-01-17
CA2587449A1 (en) 2006-05-18
NO20072966L (no) 2007-08-10

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