WO2006046651A1 - 医療用ワイヤ - Google Patents
医療用ワイヤ Download PDFInfo
- Publication number
- WO2006046651A1 WO2006046651A1 PCT/JP2005/019800 JP2005019800W WO2006046651A1 WO 2006046651 A1 WO2006046651 A1 WO 2006046651A1 JP 2005019800 W JP2005019800 W JP 2005019800W WO 2006046651 A1 WO2006046651 A1 WO 2006046651A1
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- WO
- WIPO (PCT)
- Prior art keywords
- wire
- coating film
- vivo indwelling
- medical
- medical wire
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M29/00—Dilators with or without means for introducing media, e.g. remedies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00477—Coupling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B2017/1205—Introduction devices
- A61B2017/12054—Details concerning the detachment of the occluding device from the introduction device
- A61B2017/12068—Details concerning the detachment of the occluding device from the introduction device detachable by heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M2025/0042—Microcatheters, cannula or the like having outside diameters around 1 mm or less
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0017—Catheters; Hollow probes specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/0045—Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
Definitions
- the present invention relates to a medical wire for placing an in-vivo indwelling member at a predetermined location in a living body.
- embolization materials for occluding catheters, guidewires, blood vessels, and other various types have been developed so that these various burdens can be alleviated and necessary operations can be performed safely and simply.
- Medical devices have been developed and put into practical use. With recent advances in medical devices such as catheters and guidewires, endovascular surgery approaching the desired affected area from inside the blood vessel has been carried out, especially arteriovenous malformations, cerebral aneurysms, It is increasingly applied to the treatment of diseases such as carotid cavernous sinus.
- vascular embolization is known as a treatment method that is less invasive to an aneurysm or the like and in which an in-vivo indwelling member having a metallic force that does not adversely affect a living body such as platinum is placed in the aneurysm.
- a medical wire in which an in-vivo indwelling member is connected to the distal end of a delivery wire is passed through a catheter placed in the living body, and the wire is manipulated under fluoroscopy with an X-ray contrast apparatus.
- the in-vivo indwelling member is guided to a desired position in the living body, the in-vivo indwelling member reaches a target location, and the in-vivo indwelling member is detached in that state.
- Mechanical means and electrical means are known as methods for detaching the in-vivo indwelling member.
- an electrical detachment means an external device is provided between a conductive wire and a counter electrode connected to the living body.
- There is a type that disassembles and melts the connecting member by supplying force current for example, special (See Permitted Document 1 and Patent Document 2).
- Patent Document 2 discloses a medical device for vascular occlusion in which an in-vivo indwelling member is connected to a distal end portion of a conductive wire via a heat-soluble rod-like connecting member that also has a polybutyl alcohol force.
- a high-frequency current is supplied between the conductive wire and the counter electrode, whereby the tip of the conductive wire functions as a heating electrode and the connecting member is It is said that since it melts instantaneously and the in-vivo indwelling member is separated from the conductive wire, the time required for the operation is short and the burden on the patient and doctor is reduced.
- Patent Document 1 Japanese Patent No. 3007022
- Patent Document 2 Japanese Patent No. 2880070
- this conventional medical wire is composed of a conductive wire body 50, a connection member 52, and an in-vivo indwelling member 54. More specifically, as shown in FIG. 10, the distal end portion of the conductive wire main body 50 is formed by a coil body 56, and the coil body 56 is interposed via a heat-soluble connection member 52. A coiled in-vivo indwelling member 54 is connected, and an insulating coating film 58 is formed on the outer peripheral surface of the wire body 50 excluding the distal end portion and the proximal end portion, and this coating film 58 is formed. A heating electrode portion is formed by the exposed coil portion E of the coil body 56 exposed without being exposed.
- the resistance value in the heating electrode section is greatly influenced by the surrounding environment where the heating electrode section is located.
- the surrounding environment where the heating electrode section is located.
- the heating electrode part Since a part of the high-frequency current supplied to the in-vivo flows into the in-vivo in-vivo member in which it is in contact and leakage occurs, the surface area of the member acting as an electrode is increased, resulting in an increase in the surface area. The resistance value in the electrode part is lowered.
- the present invention has been made in the background as described above, and the purpose thereof is to connect the in-vivo indwelling member to the distal end portion of the conductive wire body via a heat-soluble connecting member.
- the in-vivo indwelling member previously disposed at the distal end portion of the conductive wire body and other conductive members that cause electric leakage (hereinafter also referred to as “leakage member”) are physically provided. Even when contact is made, a medical wire that can generate the desired heat generation due to the fact that electric leakage occurs in the heating electrode portion of the wire body, and can reliably remove the in-vivo indwelling member. It is to provide.
- the medical wire of the present invention comprises a conductive wire main body and an in-vivo indwelling member connected to the distal end portion of the wire main body via a heat-soluble connecting member, and passes through the wire main body.
- the connecting wire is heated and melted by supplying a fusing current, whereby the in-vivo indwelling member is detached,
- a non-conductive coating film is formed on the outer peripheral surface of the electrode forming portion at the tip of the wire body, and a part of the surface of the wire body is exposed through the coating film.
- a heating electrode portion is formed.
- the heating electrode portion is preferably formed by a plurality of minute notches formed in the coating film.
- the total area of the plurality of notches is 0.005 mm 2 or more, and the thickness of the coating film is preferably 0.001 to 0.1 mm.
- the notch may be formed by a circular or elliptical opening, or a semicircular or semi-elliptical concave notch formed from a leading edge of the coating film,
- at least one of the cutout portions may be formed by a concave cutout formed from the leading edge of the coating film.
- the notch is formed of three semicircular concave notches formed from the tip edge of the coating film, and It is preferable that it is made up of three circular openings formed in the region located on the hand side.
- the in-vivo indwelling member is formed by a coil material made of a metal filament, and the notch portion formed in the coating film has a maximum width dimension of the in-vivo indwelling member. It is preferable that the outer diameter of the coil material to be formed is smaller.
- the in-vivo indwelling member is selected from platinum, tungsten, gold, tantalum, iridium, palladium, and their alloy strength.
- the material of the coating film is preferably selected from polytetrafluoroethylene, fluorinated ethylene propylene resin, polyfluorinated alkylene, polyethylene, polyethylene terephthalate, polyamide and polyimide.
- a non-conductive coating film is formed on the outer peripheral surface of the electrode forming portion at the distal end portion of the conductive wire body.
- a heating electrode portion is formed by exposing a part of the surface of the wire body. Therefore, by supplying a high-frequency current through the wire body, Joule heat is generated by the electrical resistance generated when the living body fluid (electrolyte solution) is in contact with the exposed surface of the wire body that forms the electrode for calorie heat. Is generated, the heat-soluble connection member is melted, and the in-vivo indwelling member is detached.
- the heating electrode portion has a non-conductive coating film formed on the outer peripheral surface, when the in-vivo indwelling member is introduced through the catheter, Even when an earth leakage member such as an indwelling member physically contacts the tip of the wire body, the earth leakage member and the wire body may be electrically connected. As a result, since the high-frequency current supplied to the wire body does not flow through the leakage member, the connecting member can be surely blown, and the in-vivo indwelling member can be separated. It can be done reliably.
- FIG. 1 is a side view showing an example of the configuration of a medical wire of the present invention.
- FIG. 2 is an explanatory side view showing an enlarged connection portion between the distal end portion of the wire body and the in-vivo indwelling member in the medical wire of FIG. 1.
- FIG. 3 is a development view showing a coating film in which a notch portion is formed in the electrode forming portion of the medical wire in the example of FIG. 2.
- FIG. 2 It is an explanatory view showing the positions of the opening and the concave cutout constituting the cutout in the example of FIG. 2, (A) is a side view, (B) is a cross-sectional view showing the arrangement of circular openings, ( C) is a cross-sectional view showing the arrangement of semicircular concave notches.
- FIG. 5 is a development view showing a case where a notch of another form is formed in the coating film.
- FIG. 6 is a development view showing a case where notches having other arrangements are formed in the coating film.
- FIG. 7 is a schematic explanatory view of an in-vivo indwelling member detachment test for a medical wire having the configuration shown in FIGS. 1 to 3.
- FIG. 8 is an explanatory view showing a state in which a leakage member is brought into contact in the in-vivo indwelling member detachment test of FIG.
- FIG. 9 is a side view showing an example of the configuration of a conventional medical wire.
- FIG. 10 is an explanatory side view showing an enlarged connection portion between the distal end portion of the wire body and the in-vivo indwelling member in the medical wire of FIG. 9.
- FIG. 1 is a side view showing a configuration of an example of a medical wire of the present invention having an in-vivo indwelling member made of a detachable embolic coil.
- This medical wire W is basically composed of a conductive wire body 10, a connection member 16, and an in-vivo indwelling member 18.
- the wire main body 10 has a stainless steel and platinum alloy coil formed on a tip end portion of a taper-like stainless alloy wire material having a diameter that decreases from the base end portion (right end side in the figure) 12 toward the tip end portion.
- the tip 14 is formed by welding over the body, and its outer diameter is about 0.2 to 1. Omm.
- a non-conductive coating film 20 is formed so as to cover the outer peripheral surface including the region of the distal end portion 14.
- the base end portion of the rod-shaped connecting member 16 is inserted and fixed in the coil body of the distal end portion 14 of the wire body 10, and the distal end portion of the connecting member 16 is inserted. By being fixed, a coiled in-vivo indwelling member 18 is connected and provided.
- connection member 16 forms a detachment portion for detaching the in-vivo indwelling member 18, and is formed of a heat-soluble material.
- a material made of a polybutyl alcohol copolymer can be preferably used.
- the connection member 16 is, for example, 70 ° C or higher using high-frequency power. It is possible to blow out by heating to the temperature.
- the outer diameter is, for example, about 0.05-0.50 mm, and the total length is about 0.1-: LOOmm.
- the in-vivo indwelling member 18 shown in the figure is formed by spirally winding a primary coil material obtained by spirally winding a platinum alloy filament having compatibility with a living body to form a secondary coil body.
- the outer diameter of the filament which is a wire material, is about 0.02-0.15 mm, and the outer diameter of the primary coil material is about 0.1 to 1.2 mm, and the secondary coil body is flexible.
- the outer diameter of this is, for example, a force of about 0.3 to 50 mm.
- Various sizes are used depending on the specific purpose of use and conditions, which are not limited to these.
- the in-vivo indwelling member may be made by using the primary coil material as it is, and has an appropriate three-dimensional shape other than the secondary coil body made by using the primary coil material. It can be a thing!
- the distal end portion of the primary coil material is preferably rounded into, for example, a hemispherical shape, which prevents the living tissue from being damaged when inserted.
- the material of the filament forming the in-vivo indwelling member 18 may be selected from platinum (platinum), tandasten, gold, tantalum, iridium, palladium, and their alloy strength. In particular, an alloy made of platinum and tungsten is particularly preferable.
- the cross-sectional shape of the filament is not limited to a circle, and various shapes such as an ellipse, a rectangle, and a triangle can be used.
- FIG. 2 is an explanatory side view showing an enlarged connection portion between the distal end portion 14 of the wire body 10 and the in-vivo indwelling member 18.
- the coating film 20 is formed in a state in which the entire outer peripheral surface of the region including the coil body that forms the distal end portion 14 of the wire body 10 is covered.
- the coating film 20 is made of a non-conductive material such as various electrically insulating polymers such as polytetrafluoroethylene (PTFE), fluorinated ethylene propylene resin (F EP), polyfluorinated alkylene (PFA), polyethylene (PE), polyethylene terephthalate (PET), polyamides such as nylon (PA), polyimide (PI), polyurethane, polypropylene, silicone resin, and other resins It can be formed by things.
- the thickness of the covering film 20 is preferably 0.001 to 0.1 mm, for example, and more preferably 0.01 to 0.1 mm.
- the coating film 20 formed in the region of the electrode forming portion, which is the tip portion 14 of the wire body 10, is formed with a plurality of minute notches 24, and the notches 24 form the wire body.
- the outer peripheral surface or outer surface of the coil body constituting the tip portion 14 of 10 is exposed, and a heating electrode portion is formed by this exposed surface portion.
- the notch 24 in the example of Fig. 2 is, as shown in Fig. 3, the leading edge 22 of the coating film 20 that matches the tip position of the coil body of the tip 14 of the wire body 10.
- the three circular openings 24A are positioned in a state where the circumferential positions thereof are different by 120 degrees, and the three semicircular concave notches 24B are similarly surrounded.
- the direction positions are different from each other by 120 degrees, and one circular opening 24A and the semicircular concave notch 24B adjacent to the circular opening 24A are different from each other by 30 degrees in the circumferential direction.
- FIG. 4 is an explanatory view showing the positional relationship between the opening and the concave notch constituting the notch in the above example
- (A) is a side view of the tip 14 of the wire body 10
- (B) Is a cross-sectional view showing the circumferential arrangement of the circular openings 24A
- (C) is a cross-sectional view showing the circumferential arrangement of the semicircular concave cutouts 24B.
- the notch 24 is one or both of an opening 24A formed by a through-hole formed in the coating film 20 and a concave notch 24B formed at the front edge of the coating film 20. It is composed of When the opening 24A is circular and the concave notch 24B is semicircular, the diameter is, for example, 0.05 to 0.15 mm, and the number thereof is, for example, 1 to 20. Accordingly, it is preferable that the total area of the notches 24, that is, the total area of the exposed surface portion at the tip portion 14 of the wire body 10 is 0.01 mm 2 or more.
- the shape of the opening 24A constituting the notch 24 can be an oval, a square, a rectangle, or any other appropriate shape, not limited to a circle, but the notch in the coating film 20 Since the possibility of breakage due to 24 is small, the opening 24A is preferably circular and the concave notch 24B is preferably semicircular.
- FIG. 5 is a developed view similar to FIG. 3, showing an example of the coating film 20 in which the square opening 24A and the triangular concave cutout 24B are formed.
- FIG. 6 is a developed view similar to FIG. 3, showing an example of the coating film 20 formed by arranging the two circular openings 24A in a zigzag shape together with the semicircular concave notches 24B. .
- the number of openings and concave cutouts constituting the cutout portion 24, the shape and arrangement of each, can be determined with a considerably large degree of freedom.
- the dimension of the maximum width of the exposed surface portion of the distal end portion 14 is smaller than the outer diameter of the primary coil material forming the in-vivo indwelling member.
- the in-vivo indwelling member having the same configuration, that is, the earth leakage member, arranged in advance is the heating electrode portion formed by the exposed surface portion of the distal end portion of the wire body. This is because it is possible to surely obtain an effect that obstructs direct contact with the substrate.
- a stainless steel wire body 10 with a diameter of 0.23 mm and a length of 1800 mm is prepared, and the outer surface of the region 1700 mm long from the tip formed by the coil body is covered with polytetra
- a coating film 20 made of fluoroethylene (PTFE) having a thickness of 0.02 to 0.04 mm is formed, and the coating film 20 in a region following the tip is formed on the coil body according to the embodiment shown in FIG.
- a cutout 24 comprising a circular opening 24A exposing the outer peripheral surface and a semicircular concave cutout 24B was formed.
- the diameter of the circle related to the opening 24A and the concave notch 24B is 0.06 mm, and the position of the circumferential line passing through the center of the three openings 24A is 0. It is a position at a distance of 8mm.
- the proximal end of a cylindrical rod-shaped connecting member 16 having a diameter of 0.1 mm and a length of 5 mm made of heat-soluble polybutyl alcohol. The portion was inserted and fixed with an adhesive made of cyanoacrylate.
- an in-vivo indwelling member 18 is obtained by forming a secondary coil body by winding a primary coil material made of a platinum alloy filament with a 0.25 mm outer diameter coiled so that the outer diameter is 2 mm.
- the distal end portion of the connection member 16 was inserted into the coil hole of the primary coil material of the indwelling member 18 and bonded and fixed with an adhesive made of cyanoacrylate, thereby producing a medical wire.
- the case electrode 31 from the high frequency power supply device 36 is bonded to the stainless steel container 30, and the container 30 is filled with physiological saline 32 and the temperature is 37 ° C. Kept warm.
- a guiding catheter 33 having an inner diameter of 1.75 mm and a length of 600 mm was fixed to the container 30, and its tip was immersed in the physiological saline 32.
- a microcatheter 35 having an inner diameter of 0.4 mm and a front length of 1500 mm was fixed so that the tip of the microcatheter 35 was immersed in the physiological saline 32 from the branch connection portion 34 provided at the proximal portion of the guiding catheter 33.
- the medical wire is introduced from the hand operating unit outside the container 30 of the microcatheter 35 with the in-vivo indwelling member 18 as the head, and the connecting member 16 and the wire body The ten tip portions 14 were advanced until they reached the position of the opening of the microcatheter 35.
- FIG. 8 a state in which a leakage member 38 made of another in-vivo indwelling member having the same configuration and form as the in-vivo indwelling member 18 is in contact with the distal end portion 14 of the wire body 10.
- the output terminal 37 of the high-frequency power supply device 36 is connected to the proximal end portion 12 of the wire body 10, and a high-frequency current with a frequency of 300 kHz and a power of 0.7 W is supplied.
- a withdrawal test was conducted.
- connection member 16 in the medical wire was instantaneously melted and the in-vivo indwelling member 18 was detached.
- the tip of the current-carrying member such as a previously placed in-vivo indwelling member
- the tip of the medical wire is non-conductive.
- the exposed surface portion of the coil body in which the earth leakage member is the heating electrode portion due to the coating film Contact with the electrode forming portion is effectively obstructed, and as a result, it is prevented from leaking to the leaking member, so that the connecting member can be surely melted and the in-vivo indwelling member is surely secured. It is clear that they are allowed to leave.
- the in-vivo indwelling member detachment test was performed in the same manner as in Example 1 except that the medical wire having the configuration shown in FIGS. 9 and 10 was used. As a result, the connecting member 52 was melted. First, the in-vivo indwelling member 54 did not come off.
- the present invention can be applied to a thrombus-forming member other than a coil and other indwelling medical devices.
- the present invention can be applied to all treatments in which various in-vivo indwelling members having an action or a medical auxiliary action are separated from the force of the conductive wire body.
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006543254A JP4740150B2 (ja) | 2004-10-29 | 2005-10-27 | 医療用ワイヤ |
KR1020077009381A KR101202369B1 (ko) | 2004-10-29 | 2005-10-27 | 의료용 와이어 |
EP05805314.1A EP1806104B1 (en) | 2004-10-29 | 2005-10-27 | Medical wire |
US11/577,086 US8021371B2 (en) | 2004-10-29 | 2005-10-27 | Medical wire |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004-315131 | 2004-10-29 | ||
JP2004315131 | 2004-10-29 |
Publications (1)
Publication Number | Publication Date |
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WO2006046651A1 true WO2006046651A1 (ja) | 2006-05-04 |
Family
ID=36227893
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2005/019800 WO2006046651A1 (ja) | 2004-10-29 | 2005-10-27 | 医療用ワイヤ |
Country Status (5)
Country | Link |
---|---|
US (1) | US8021371B2 (ja) |
EP (1) | EP1806104B1 (ja) |
JP (1) | JP4740150B2 (ja) |
KR (1) | KR101202369B1 (ja) |
WO (1) | WO2006046651A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1962701B1 (en) * | 2005-12-19 | 2011-08-24 | Boston Scientific Limited | Embolic coils made from a wound ribbon |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101048107A (zh) * | 2004-10-29 | 2007-10-03 | 株式会社钟化 | 医疗用线 |
JP5986320B2 (ja) * | 2012-10-19 | 2016-09-06 | クック・メディカル・テクノロジーズ・リミテッド・ライアビリティ・カンパニーCook Medical Technologies Llc | 自己巻取り式スタイレット針デバイス |
FR3008304B1 (fr) * | 2013-07-15 | 2016-04-01 | Balt Extrusion | Endoprothese pour le traitement notamment d'un anevrisme |
EP3082660B1 (en) | 2013-12-20 | 2020-01-22 | Microvention, Inc. | Device delivery system |
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JP2000229086A (ja) * | 1999-02-10 | 2000-08-22 | Kaneka Medeikkusu:Kk | 生体内留置部材を有する医療用ワイヤーおよびその使用方法 |
JP2001513390A (ja) * | 1997-08-29 | 2001-09-04 | ボストン サイエンティフィック リミテッド | 迅速取り外し電気絶縁インプラント |
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JP2880070B2 (ja) * | 1994-03-31 | 1999-04-05 | 株式会社カネカメディックス | 生体内留置部材を有する医療用ワイヤー |
US5458596A (en) * | 1994-05-06 | 1995-10-17 | Dorsal Orthopedic Corporation | Method and apparatus for controlled contraction of soft tissue |
JP3007022B2 (ja) * | 1995-05-19 | 2000-02-07 | 株式会社カネカメディックス | 加熱用高周波電源装置 |
US5770994A (en) * | 1995-11-02 | 1998-06-23 | Cooper Industries, Inc. | Fuse element for an overcurrent protection device |
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- 2005-10-27 KR KR1020077009381A patent/KR101202369B1/ko active IP Right Grant
- 2005-10-27 US US11/577,086 patent/US8021371B2/en active Active
- 2005-10-27 EP EP05805314.1A patent/EP1806104B1/en active Active
- 2005-10-27 JP JP2006543254A patent/JP4740150B2/ja active Active
- 2005-10-27 WO PCT/JP2005/019800 patent/WO2006046651A1/ja active Application Filing
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Cited By (1)
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EP1962701B1 (en) * | 2005-12-19 | 2011-08-24 | Boston Scientific Limited | Embolic coils made from a wound ribbon |
Also Published As
Publication number | Publication date |
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US20090227899A1 (en) | 2009-09-10 |
JP4740150B2 (ja) | 2011-08-03 |
EP1806104A4 (en) | 2015-01-14 |
KR101202369B1 (ko) | 2012-11-16 |
US8021371B2 (en) | 2011-09-20 |
KR20070072544A (ko) | 2007-07-04 |
EP1806104A1 (en) | 2007-07-11 |
JPWO2006046651A1 (ja) | 2008-05-22 |
EP1806104B1 (en) | 2016-08-24 |
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