WO2006042287A3 - Procede de production d'echafaudages de biomateriaux - Google Patents

Procede de production d'echafaudages de biomateriaux Download PDF

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Publication number
WO2006042287A3
WO2006042287A3 PCT/US2005/036724 US2005036724W WO2006042287A3 WO 2006042287 A3 WO2006042287 A3 WO 2006042287A3 US 2005036724 W US2005036724 W US 2005036724W WO 2006042287 A3 WO2006042287 A3 WO 2006042287A3
Authority
WO
WIPO (PCT)
Prior art keywords
scaffold
biomaterial scaffolds
microchannels
polymer
layers
Prior art date
Application number
PCT/US2005/036724
Other languages
English (en)
Other versions
WO2006042287A2 (fr
Inventor
David L Kaplan
Peter Y Wong
Original Assignee
Tufts College
David L Kaplan
Peter Y Wong
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tufts College, David L Kaplan, Peter Y Wong filed Critical Tufts College
Priority to US11/664,234 priority Critical patent/US20080280360A1/en
Publication of WO2006042287A2 publication Critical patent/WO2006042287A2/fr
Publication of WO2006042287A3 publication Critical patent/WO2006042287A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/78—Cellulose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2535/00—Supports or coatings for cell culture characterised by topography
    • C12N2535/10—Patterned coating

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Prostheses (AREA)

Abstract

L'invention concerne un échaudage multicouches destiné à l'ingénierie des tissus. L'échafaudage de l'invention comprend au moins une première couche composée d'un polymère dans lequel est formé un motif de microcanaux; et au moins une seconde couche composée d'un polymère dans lequel est formé un motif de microcanaux. La première et la seconde couche sont unies entre elles (de préférence par stratification) et les canaux sont reliés afin de permettre la circulation de liquides à travers les couches précitées. L'échafaudage est revêtu d'une cellulose bactérienne. L'échafaudage peut comprendre une cellule mammalienne.
PCT/US2005/036724 2004-10-12 2005-10-12 Procede de production d'echafaudages de biomateriaux WO2006042287A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US11/664,234 US20080280360A1 (en) 2004-10-12 2005-10-12 Method for Producing Biomaterial Scaffolds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61791904P 2004-10-12 2004-10-12
US60/617,919 2004-10-12

Publications (2)

Publication Number Publication Date
WO2006042287A2 WO2006042287A2 (fr) 2006-04-20
WO2006042287A3 true WO2006042287A3 (fr) 2006-07-27

Family

ID=36149021

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/036724 WO2006042287A2 (fr) 2004-10-12 2005-10-12 Procede de production d'echafaudages de biomateriaux

Country Status (2)

Country Link
US (1) US20080280360A1 (fr)
WO (1) WO2006042287A2 (fr)

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US8886334B2 (en) 2008-10-07 2014-11-11 Mc10, Inc. Systems, methods, and devices using stretchable or flexible electronics for medical applications
US8934965B2 (en) 2011-06-03 2015-01-13 The Board Of Trustees Of The University Of Illinois Conformable actively multiplexed high-density surface electrode array for brain interfacing
US9012784B2 (en) 2008-10-07 2015-04-21 Mc10, Inc. Extremely stretchable electronics
US9159635B2 (en) 2011-05-27 2015-10-13 Mc10, Inc. Flexible electronic structure
US9171794B2 (en) 2012-10-09 2015-10-27 Mc10, Inc. Embedding thin chips in polymer
US9289132B2 (en) 2008-10-07 2016-03-22 Mc10, Inc. Catheter balloon having stretchable integrated circuitry and sensor array
US9450043B2 (en) 2004-06-04 2016-09-20 The Board Of Trustees Of The University Of Illinois Methods and devices for fabricating and assembling printable semiconductor elements
US9554484B2 (en) 2012-03-30 2017-01-24 The Board Of Trustees Of The University Of Illinois Appendage mountable electronic devices conformable to surfaces
US12074213B2 (en) 2021-06-24 2024-08-27 The Board Of Trustees Of The University Of Illinois Methods and devices for fabricating and assembling printable semiconductor elements

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US20070128243A1 (en) * 2005-12-02 2007-06-07 Xylos Corporation Implantable microbial cellulose materials for various medical applications
DE102007006843A1 (de) 2007-02-12 2008-08-14 Bioregeneration Gmbh Verfahren und Stützstruktur zum Kultivieren lebender Zellen
CN104013598A (zh) 2007-05-29 2014-09-03 塔夫茨大学信托人 利用超声处理使丝纤蛋白凝胶化的方法
EP2291510A2 (fr) * 2008-05-27 2011-03-09 Aarhus Universitet Matériaux biocompatibles pour une croissance et une différenciation de cellules souches de mammifères
AU2009302192B2 (en) 2008-06-18 2014-08-28 Trustees Of Tufts College Modified silk films containing glycerol
US8372726B2 (en) 2008-10-07 2013-02-12 Mc10, Inc. Methods and applications of non-planar imaging arrays
US8097926B2 (en) 2008-10-07 2012-01-17 Mc10, Inc. Systems, methods, and devices having stretchable integrated circuitry for sensing and delivering therapy
EP2346540B1 (fr) * 2008-11-07 2013-04-03 Sofradim Production Dispositif médical comprenant de la cellulose bactérienne avec renfort utilisant des matériaux de renfort résorbables
US9107978B2 (en) 2008-11-07 2015-08-18 Sofradim Production Template for bacterial cellulose implant processed within bioreactor
US8962006B2 (en) * 2008-11-07 2015-02-24 Sofradim Production Composite mesh including a 3D mesh and a non porous film of oxidized cellulose from bacterial cellulose origin
WO2010065908A2 (fr) * 2008-12-05 2010-06-10 Catchmark Jeffrey M Compositions de biomolécule dégradables
US20110171180A1 (en) * 2009-03-19 2011-07-14 Worcester Polytechnic Institute Bioengineered skin substitutes
WO2011005381A2 (fr) 2009-06-01 2011-01-13 Trustees Of Tufts College Gélification de la fibroïne par traitement au vortex servant dans des applications d’encapsulation et d’administration
US9016875B2 (en) 2009-07-20 2015-04-28 Tufts University/Trustees Of Tufts College All-protein implantable, resorbable reflectors
US8691974B2 (en) 2009-09-28 2014-04-08 Virginia Tech Intellectual Properties, Inc. Three-dimensional bioprinting of biosynthetic cellulose (BC) implants and scaffolds for tissue engineering
WO2011038401A2 (fr) 2009-09-28 2011-03-31 Trustees Of Tufts College Fibres de soie électrogélifiées étirées et leurs procédés de production
US9723122B2 (en) 2009-10-01 2017-08-01 Mc10, Inc. Protective cases with integrated electronics
WO2011044116A2 (fr) * 2009-10-05 2011-04-14 The Charles Stark Draper Laboratory, Inc. Plateformes microfluidiques tridimensionnelles et leurs procédés d'utilisation et de fabrication
WO2011047047A2 (fr) * 2009-10-13 2011-04-21 The Penn State Research Foundation Composites contenant des polypeptides attachés à des polysaccharides et des molécules
US10441185B2 (en) 2009-12-16 2019-10-15 The Board Of Trustees Of The University Of Illinois Flexible and stretchable electronic systems for epidermal electronics
US9936574B2 (en) 2009-12-16 2018-04-03 The Board Of Trustees Of The University Of Illinois Waterproof stretchable optoelectronics
JP6046491B2 (ja) 2009-12-16 2016-12-21 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ コンフォーマル電子機器を使用した生体内での電気生理学
CN105496423A (zh) 2010-03-17 2016-04-20 伊利诺伊大学评议会 基于生物可吸收基质的可植入生物医学装置
US8790699B2 (en) * 2010-04-23 2014-07-29 Warsaw Orthpedic, Inc. Foam-formed collagen strand
US8460691B2 (en) * 2010-04-23 2013-06-11 Warsaw Orthopedic, Inc. Fenestrated wound repair scaffold
EP2563416B1 (fr) 2010-04-30 2016-11-09 Sofradim Production Dispositif médical contenant de la cellulose et qui présente une structure multicouche produite sans adhésif
CN103328034A (zh) 2010-09-03 2013-09-25 塔夫茨大学/塔夫茨学院信托人 掺杂有等离子体纳米颗粒的丝材
EP2622663A4 (fr) 2010-09-27 2014-12-24 Tufts University Trustees Of Tufts College Matériaux piézoélectriques à base de soie
US10933173B2 (en) 2010-10-19 2021-03-02 Trustees Of Tufts College Silk fibroin-based microneedles and methods of making the same
WO2012140325A1 (fr) * 2011-04-15 2012-10-18 Aalto University Foundation Procédé de test in vitro destiné à des matériaux d'implant
WO2012158709A1 (fr) 2011-05-16 2012-11-22 The Board Of Trustees Of The University Of Illinois Barrettes de del à gestion thermique assemblées par impression
US20140370094A1 (en) 2011-11-08 2014-12-18 Tufts University Silk-based scaffold platform for engineering tissue constructs
MX2014005702A (es) 2011-11-09 2015-02-17 Tufts College Particulas de fibroina de seda inyectables y sus usos.
WO2013071123A1 (fr) 2011-11-09 2013-05-16 Trustees Of Tufts College Mousses de fibroïne de soie injectables et leurs utilisations
WO2013089867A2 (fr) 2011-12-01 2013-06-20 The Board Of Trustees Of The University Of Illinois Dispositifs transitoires conçus pour subir des transformations programmables
BR112014016154A8 (pt) 2011-12-29 2017-07-04 Tufts College funcionalização de biomateriais para controlar respostas à regeneração e inflamação
EP2811987B1 (fr) 2012-02-06 2021-01-20 Children's Medical Center Corporation Biomatériau multicouche destiné à la régénération de tissus et la cicatrisation de plaies
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WO2013163407A1 (fr) 2012-04-25 2013-10-31 Trustees Of Tufts College Microsphères de soie et procédés de lubrification de surface
WO2014011775A1 (fr) 2012-07-10 2014-01-16 The Trustees Of The University Of Pennsylvania Biomatériaux destinés à améliorer l'intégration de l'implant au sein de l'hôte
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DE102013005198B4 (de) * 2013-03-25 2016-05-19 Xellutec Gmbh Verfahren und Vorrichtung zum Herstellen einer Zellkultur aus menschlichen oder tierischen Zellen
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US20150216682A1 (en) 2014-02-06 2015-08-06 The Charles Stark Draper Laboratory, Inc. Array of Microelectrodes for Interfacing to Neurons within Fascicles
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US11439668B2 (en) 2014-05-23 2022-09-13 JangoBio, LLC Methods to differentiate stem cells into hormone-producing cells
US11253549B2 (en) 2014-05-23 2022-02-22 JangoBio, LLC Methods to rebalance the hypothalamic-pituitary-gonadal axis
US10328178B2 (en) 2014-05-30 2019-06-25 Sofradim Production Implant comprising oxidized cellulose and method for preparing such an implant
US11029198B2 (en) 2015-06-01 2021-06-08 The Board Of Trustees Of The University Of Illinois Alternative approach for UV sensing
MX2017015586A (es) 2015-06-01 2018-08-23 Univ Illinois Sistemas electronicos miniaturizados con capacidades de energia inalambrica y comunicacion de campo cercano.
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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9450043B2 (en) 2004-06-04 2016-09-20 The Board Of Trustees Of The University Of Illinois Methods and devices for fabricating and assembling printable semiconductor elements
US8886334B2 (en) 2008-10-07 2014-11-11 Mc10, Inc. Systems, methods, and devices using stretchable or flexible electronics for medical applications
US9012784B2 (en) 2008-10-07 2015-04-21 Mc10, Inc. Extremely stretchable electronics
US9289132B2 (en) 2008-10-07 2016-03-22 Mc10, Inc. Catheter balloon having stretchable integrated circuitry and sensor array
US9159635B2 (en) 2011-05-27 2015-10-13 Mc10, Inc. Flexible electronic structure
US8934965B2 (en) 2011-06-03 2015-01-13 The Board Of Trustees Of The University Of Illinois Conformable actively multiplexed high-density surface electrode array for brain interfacing
US9554484B2 (en) 2012-03-30 2017-01-24 The Board Of Trustees Of The University Of Illinois Appendage mountable electronic devices conformable to surfaces
US9171794B2 (en) 2012-10-09 2015-10-27 Mc10, Inc. Embedding thin chips in polymer
CN103861154A (zh) * 2014-03-31 2014-06-18 宁夏医科大学 一种新型双层复合骨组织工程支架及其制备方法
CN103861154B (zh) * 2014-03-31 2016-02-24 宁夏医科大学 一种双层复合骨组织工程支架及其制备方法
US12074213B2 (en) 2021-06-24 2024-08-27 The Board Of Trustees Of The University Of Illinois Methods and devices for fabricating and assembling printable semiconductor elements

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Publication number Publication date
US20080280360A1 (en) 2008-11-13
WO2006042287A2 (fr) 2006-04-20

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