WO2006034826A1 - Composition de boisson de soins de la peau - Google Patents
Composition de boisson de soins de la peau Download PDFInfo
- Publication number
- WO2006034826A1 WO2006034826A1 PCT/EP2005/010335 EP2005010335W WO2006034826A1 WO 2006034826 A1 WO2006034826 A1 WO 2006034826A1 EP 2005010335 W EP2005010335 W EP 2005010335W WO 2006034826 A1 WO2006034826 A1 WO 2006034826A1
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- WO
- WIPO (PCT)
- Prior art keywords
- skin
- beverage
- skin care
- care beverage
- ready
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Definitions
- the present invention relates to a skin care beverage composition. Particularly, it relates to ready-to-drink, liquid concentrate, and dry mix skin care beverages containing the composition.
- the invention also relates to methods of providing skin protection and skin nourishment to a person in need.
- Topical application is the most common method to provide skin with active ingredients also including nutrients.
- topically applicable compositions in the form of cremes, lotions etc. are used to treat selected local portions of the skin, for example face and hands.
- skin beauty may be addressed as preventing or slowing-down the natural aging process.
- environmental stress factors particularly sun/UV-light exposure
- Skin atrophy reflects thinning of skin and skin appendages. Skin will get thinner including epidermis and dermis. Connective tissue architecture becomes notably altered and elasticity will become reduced. Epidermal and dermal changes are related to environmental stress such as UV-exposure, smoking etc.
- the skin will get dryer.
- the sebaceous glands increase in size but produce less skin lipids.
- Skin becomes more sensitive to detergents and irratative substances. For sebum, these changes are mostly associated with aging and hormonal changes. The relationship with external stress is less obvious.
- pigmentation disorders involve development of brownish spots/tones (hyper-pigmentation) at the sides of accumulated and high sun exposure, for example face, hands etc.
- Pigment cell number as well as pigment production can increase.
- Pigmentation is usually not desired by the individuals as increased pigmentation affects the outer appearance.
- Skin health and skin beauty are considered to be in a mutual relationship.
- a healthy skin gives a firm, smooth, soft and "radiant" outer appearance which contributes to the general well-being of an individual.
- Skin nourishment is also an essential prerequisite for a healthy skin. Skin nourishment is important to provide the skin with sufficient firmness and hydration/moisture.
- topical application is associated with treatment of local skin areas only, it would be desirable to have available a composition which can be taken orally in order to provide the whole skin area with necessary care in terms of ingredients for protection and nourishment.
- skin care beverage composition should be understood to mean a composition suitable to form a skin care beverage after interaction with a liquid medium.
- skin care beverages are a ready-to-drink, dry mix, granules and liquid concentrate.
- the invention provides skin care beverage compositions including: a ready-to-drink, liquid concentrate and dry mix skin care beverages comprising the composition; a method of providing skin protection and skin nourishment to a patient in need, a non-therapeutic method of providing skin protection and skin nourishment to an individual and the use of a skin care beverage '' composition for preparing a skin care beverage product.
- a skin care beverage composition comprises a photoprotection agent comprising a mixture of biological antioxidants comprising green tea solids, tocopherols, tocotrienols, carotenoides and/or vitamin C and an agent for skin nourishment comprising at least one polyunsaturated acid and/or an agent for improving collagen synthesis comprising glycine, proline, hydroxyproline and/or arginine.
- a skin care beverage comprises a composition as defined above.
- a method of providing skin protection and skin nourishment to a patient in need comprises the step of administering an effective amount of a skin care beverage composition comprising a photoprotection agent comprising a mixture of biological antioxidants comprising green tea solids, tocopherols, tocotrienols, carotenoides and/or vitamin C and an agent for skin nourishment comprising at least one polyunsaturated acid and/or an agent for improving collagen synthesis comprising glycine, proline, hydroxyproline and/or arginine.
- a photoprotection agent comprising a mixture of biological antioxidants comprising green tea solids, tocopherols, tocotrienols, carotenoides and/or vitamin C
- an agent for skin nourishment comprising at least one polyunsaturated acid and/or an agent for improving collagen synthesis comprising glycine, proline, hydroxyproline and/or arginine.
- a non- therapeutic method of providing skin protection and skin nourishment to an individual comprises the step of ingesting an effective amount of a skin care beverage comprising a photoprotection agent comprising a composition comprising a mixture of biological antioxidants comprising green tea solids, tocopherols, tocotrienols, carotenoides and/or vitamin C and an agent for skin nourishment comprising at least one polyunsaturated acid and/or an agent for improving collagen synthesis comprising glycine, proline, hydroxyproline and/or arginine.
- a photoprotection agent comprising a composition comprising a mixture of biological antioxidants comprising green tea solids, tocopherols, tocotrienols, carotenoides and/or vitamin C
- an agent for skin nourishment comprising at least one polyunsaturated acid and/or an agent for improving collagen synthesis comprising glycine, proline, hydroxyproline and/or arginine.
- a skin care beverage composition comprising a photoprotection agent comprising a mixture of biological antioxidants comprising green tea solids, tocopherols, tocotrienols, carotenoides and/or vitamin C and an agent for skin nourishment comprising at least one polyunsaturated acid, is used for preparing a skin care beverage and/or an agent for improving collagen synthesis comprising glycine, proline, hydroxyproline and/or arginine.
- a skin care beverage composition comprising a photoprotection agent comprising a mixture of biological antioxidants comprising green tea solids, tocopherols, tocotrienols, carotenoides and/or vitamin C and an agent for skin nourishment comprising at least one polyunsaturated acid, exhibits benefits related to skin health and skin beauty.
- the skin care composition of the present invention being carried through a beverage, allows the whole area of skin to be improved through systemic distribution of required biologically active agents. This is the decisive advantage over traditional skin nourishment/protection compositions which are applied topically, i.e., locally on certain skin portions. As a result of good protection and good nourishment, an excellent skin hydration is achieved.
- photoprotection agents are green tea extract and fractions thereof, polyphenols, betalains (beet pigments), anthocyanins, vitamins such as C, E; Co-QlO, glutathione, carotenoids, metals such as selenium or zinc, taurine, tocotrienol, tocopherols, ellagic acid and isoflavones. They may be used alone or in any combination thereof.
- the photoprotection agent of the skin care beverage composition of the present invention comprises a mixture of specific photoprotection agents which are biological antioxidants.
- the mixture of biological antioxidants comprises green tea solids, tocopherols, tocotrienols, carotenoids and/or vitamin C.
- the mixture of biological antioxidants comprises at least two of the above antioxidants, more preferably three of them, especially preferred four of them and most preferred all of them.
- lutein zeaxanthin
- ⁇ -carotene lycopene
- ⁇ -cryptoxanthin ⁇ -cryptoxanthin
- astaxanthin a mixture of lutein, zeaxanthin, ⁇ -carotene, lycopene, ⁇ -cryptoxanthin, and/or astaxanthin is preferred.
- a skin care beverage composition based on high quality, catechin rich, green tea solids, bioavailable carotenoids, tocopherols, tocotrienols and ascorbic acid (vitamin C) is particularly useful as a photoprotective aid in skin health.
- the specific combination of said biological antioxidants in the skin care beverage composition of the present invention has shown to provide a unique barrier against photooxidative damage at the point of exposure and to limit subsequent damage caused by immune response to sun damage and/or reactive oxygen species produced by exposure to the sun.
- this combination provides improved stability of the bioactive components .
- inclusion of tea solids enhances the stability of labile carotenoids and tocopherols in the beverage during process and through shelf life.
- a particularly preferred mixture of biological antioxidants comprises green tea solids, vitamin E, vitamin C and carotenoids providing perfect skin protection against photo damage, free radicals and oxidative stress.
- the amount of green tea solids in the mixture of biological antioxidants is preferably in a range of
- the amount of vitamin E is preferably in a range of 1 % DV/serving to 1000 % DV serving.
- the amount of vitamin C is advantageously in a range of 1 % DV/serving to 1000 % DV/serving.
- the carotenoids are preferably contained in the mixture of biological antioxidants in a range of 0.1 mg/serving to 20 g/serving.
- the skin care beverage composition of the present invention also comprises an agent for skin nourishment comprising at least one polyunsaturated acid.
- the polyunsaturated acid is an omega fatty acid.
- the agent for skin nourishment is a combination of different omega fatty acids.
- the omega fatty acids are selected from omega-3, omega-6, omega-9 fatty acids and mixtures thereof.
- the combination of omega fatty acids provides perfect nourishment of the skin by providing precursors for lipids that improve skin barrier function.
- PUFAs polyunsaturated acids
- EPA eicosapentaenoic acid
- DHA docosahexaenoic acid
- GLA gamma-linolenic acid
- stearidonic acid examples of the polyunsaturated acids. They may be used alone or in any combination thereof.
- the omega fatty acid(s) are present in the skin care beverage composition of the present invention in an amount of 0.1 mg/serving to 20 g/serving.
- the skin care beverage composition of the present invention may also comprise an agent for improving collagen synthesis comprises glycine, proline, hydroxyproline and/or arginine.
- Proline and glycine are the major amino acids constituting collagen, arginine a precursor for proline thus indirectly supporting collagen synthesis.
- proline and glycine in some instances also hydroxyproline, are essential elements for collagen build ⁇ up, vitamin C and copper both required for collagen processing, should be simultaneously present. Arginine in combination may augment this process.
- the amount of proline/glycine/arginine in the skin care beverage composition of the present invention is preferably in a range of 0.1 mg/serving to 20g/serving.
- the skin care beverage composition of the present invention comprises the above amino acids, instead of the polyunsaturated acid(s) .
- the skin care beverage composition of the invention preferably further comprises skin care agents selected from the group consisting of anti-inflammatory agents, anti-aging agents, hair growth agents, skin immunity agents, skin pigmentation agents, skin perfusion agents and skin repair agents.
- anti-aging agents examples include vitamins such as A, C, E; carotenoids, glutathione, whey protein, metals such as selenium, zinc; and taurine. They may be used either singly or in any combination thereof.
- Skin immunological parameters may be improved by nucleotides, arginine, glutathione and carotenoids. They can be used alone or in any combination thereof.
- a skin pigmentation agent for example, tyrosine is a suitable agent.
- arginine for example, may be used.
- vitamins such as Bl, B2, B6, B12, C, D, E, biotin, nicotinic acid, panthotenic acid, fatty acids such as linoleic acid and oleic acid, glutathione, carotenoids, chlorophylls and chlorophyllins
- metals such as selenium, zinc and copper; taurine, tocotrienols, ellagic acid, isoflavones. They may be used singly or in any combination thereof.
- hair growth agents are vitamins such as Bl, B2, B ⁇ , B12, C, D, E, K; biotin, nicotinic acid, panthotenic acid, fatty acids such as linoleic acid and oleic acid, metals such as zinc; amino acids and the derivatives thereof such as glycine, cyst(e)ine taurine and methionine and proanthocyanidins. These agents may be used singly or in any combination thereof.
- the skin care beverage composition of the present invention further comprises at least one other component having skin nourishment function contributing to hydration/moisture and firmness of the skin.
- Said component having a skin nourishment function is selected from the group consisting of epidermal barrier function agents, coenzymes, coenzyme precursors, lipids, carotenoids, vitamins and trace elements.
- epidermal barrier function agents comprise vitamins such as Bl, B2, B ⁇ , B12, C, E, K; biotin, nicotinic acid, panthotenic acid, fatty acids such as linoleic acid and oleic acid, metals such as calcium and zinc; amino acids and the derivatives thereof such as taurine, glutamin, glycine, cyst(e)ine and methionine. They may be used alone or in any combination thereof.
- the coenzymes and coenzymes precursors may comprise biotin, nicotinic acid and panthotenic acid.
- the lipids suitable for skin nourishment are for example linoleic acid including ⁇ -linoleic acid preferably from blackcurrant seed oil, and oleic acid.
- the carotenoids may be selected from ⁇ -carotene, zeaxanthine, lutein, ⁇ -cryptoxanthin and lycopene.
- Trace elements may be selected from metals such as zinc,- copper and selenium.
- vitamin A either as retinal or a provitamin A carotenoid
- An additional amount of vitamin A supports augmentation of collagen/connective tissue production.
- a skin care beverage comprises the above defined composition.
- the skin care beverage compositions of the invention are used for preparing a skin care beverage such as ready-to- drink, liquid concentrate and dry mix skin care beverages. With respect to components used, it is referred to the above description on ingredients.
- the skin care beverage composition of the present invention may be provided as a dry mix or as a liquid concentrate.
- a dry mix may be obtained by spray or freeze drying of the liquid beverages prior to packaging or by uniform blending or co-agglomerating of dry ingredients .
- the beverage When the beverage is to be prepared for consumption, it simply can be reconstituted by the addition of a liquid such as water.
- a skin care dry mix or liquid concentrate may be also provided as suitable food supplements in addition to the daily food an individual is usually consuming. Examples therefore are tablets, gellules, capsules, sirups etc.
- the skin care beverage composition of the present invention may be also packaged in the form of a liquid concentrate.
- These beverage concentrates may be provided as, for example, a syrup and/or aqueous concentrate.
- the beverage concentrate is typically formulated to provide a drinkable beverage composition when the concentrate is reconstituted or diluted with water or other fluid or liquid such as juice.
- the skin care beverage composition according to the present invention may be also provided as a ready-to-drink beverage.
- Such ready-to-drink skin care beverage contains the above defined skin care beverage composition and a beverage base.
- the beverage base is a liquid or fluid suitable for diluting the composition of the present invention.
- beverage base are coffee, tea, juice, milk, milk substitutes, milk products such as yoghurt and/or general flavored beverages on the basis of water.
- the amount of water, water-based liquids, milk or mixtures thereof utilized in the present ready-to-drink skin care beverage comprises at least 60 % to about 97 %, more preferably at least about 75 %, even more preferably at least 80 % and most preferably at least about 83 %.
- a ready-to-drink beverage is a milk based skin care liquid beverage or a juice based skin care liquid beverage.
- a ready-to-drink beverage is a dairy product such as a yoghurt (in scoopable or liquid form) .
- compositions of the present invention may further comprise additional optional components to enhance, for example, their performance in providing organoleptic properties and nutritional profile.
- additional optional components for example, one or more acidulants, colouring agents, low-caloric sweeteners, flavoring agents, fruit/vegetable juices, preservatives, emulsifiers/hydrocolloids, oils, carbonation components and the like may be included in the compositions herein.
- Such optional components may be dispersed, solubilized or otherwise dispersed into the present compositions.
- compositions are made according to methods which will be well known to the person skilled in the art. For convenience, non-limiting examples of methods of preparation using the compositions of the present invention are shown.
- compositions of the present invention may be prepared by dissolving, dispersing, or otherwise mixing all components singularly or in suitable combinations together and in water where appropriate, agitating with a mechanical stirrer until all of the ingredients have been solubilized or adeguately dispersed. Where appropriate, all separate solutions and dispersions may then be combined.
- tea extracts which typically are pH sensitive, it is important to adjust the desired pH with an acidulant and/or buffer system before adding the tea extract to the mixture.
- the final mixture can optionally, but preferably, be either pasteurized, ultra-pasteurized, sterilized or filled aseptically at appropriate process conditions. Sometimes chemical preservation may also be used.
- a beverage concentrate may optionally be formed first .
- One method to prepare the concentrate form of the beverage composition would be to start with less than the required volume of water that is used in the preparation of the beverage composition.
- Another method would be to partially dehydrate the finally prepared beverage compositions to remove only a portion of the water and any other volatile liquids present. Dehydration may be accomplished in accordance with well known procedures, such as evaporation under vacuum.
- the concentrate can be in the form of a relatively thick liquid.
- a syrup is typically formed by adding suitable ingredients such as electrolytes or emulsions to the beverage concentrate.
- the syrup is then mixed with water or another aqueous fluid to form a finished beverage or finished beverage concentrate.
- the weight ratio of water to syrup is typically from about 1: 1 to about 7:1.
- the final beverage is bottled or packaged in single serve containers, either in bottles, cans, or Tetrabriks .
- plastic (HDPT, PET, PP) or glass bottles are appropriately sterilized before being filled by the pasteurized or sterilized beverage.
- Beverage concentrates and beverage concentrates would be packages in both single serve multiple serve containers of the same make.
- the skin care beverage composition claimed is of therapeutic value. Patients suffering from long-term sun damage or age-related skin atrophy can be effectively treated by administering a therapeutically effective amount of the skin care beverage composition as defined above. The patients treated experience a rapid skin repair and skin build-up. The damaged skin gets firmer, smoother and softer with a radiant appearance.
- the skin care beverage composition is given as a ready-to-drink beverage. It has been shown that already after a four week treatment subjects notice improvements in their skin quality.
- the skin care beverage composition of the present invention is also applicable in a non-therapeutic method by providing skin protection and skin nourishment to an individual who desires a balanced skin health whenever it is convenient or appropriate.
- the skin care beverage composition of the invention is preferably simply ingested in the form of a ready-to-drink beverage containing the skin care beverage composition.
- the skin gets smoother, firmer and more radiant while protection from outside, i.e., environmental stress, is provided. It has been shown that good results may be obtained after a regular up-take of the composition of the invention for six weeks.
- a skin care beverage composition is prepared by combining the following components in a conventional manner.
- Green tea solids 0.100 - 0.60
- Astaxanthin 0.001 - 0.03 ⁇ -Cryptoxanthin 0.001 - 0.03
- Vitamin E mixtureed tocopherols 30 IU and tocotrienols
- a ready-to-drink skin care beverage is prepared by combining the following components in a conventional manner .
- a skin care liquid beverage concentrate composition is prepared by combining the following components in a conventional manner.
- a milk based skin care liquid beverage is prepared by combining the following components in a conventional manner.
- Flavouring additives 0.200 proline 0.053 glycine 0.009 alpha tocpheryl acetate 0.004 blackcurrant seed oil 0.587
- Examples 1-4 Beverages of Examples 1-4 were found to be palatable and refreshing. Consumers of these beverages found that their skin quality improved. Also, the components used in these beverages were found to be more accepted compared to prior art beverages that contain skin health ingredients and or similar non-natural ingredients.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Non-Alcoholic Beverages (AREA)
- Tea And Coffee (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05793352A EP1814412A1 (fr) | 2004-09-27 | 2005-09-23 | Composition de boisson de soins de la peau |
MX2007003632A MX2007003632A (es) | 2004-09-27 | 2005-09-23 | Composicion de bebida para el cuidado de la piel. |
BRPI0516137-1A BRPI0516137A (pt) | 2004-09-27 | 2005-09-23 | composição de bebida para cuidados com a pele |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04022987.4 | 2004-09-27 | ||
EP04022987 | 2004-09-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006034826A1 true WO2006034826A1 (fr) | 2006-04-06 |
WO2006034826B1 WO2006034826B1 (fr) | 2006-11-09 |
Family
ID=34926738
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2005/010335 WO2006034826A1 (fr) | 2004-09-27 | 2005-09-23 | Composition de boisson de soins de la peau |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1814412A1 (fr) |
CN (1) | CN101026966A (fr) |
AR (1) | AR051039A1 (fr) |
BR (1) | BRPI0516137A (fr) |
CR (1) | CR8999A (fr) |
MX (1) | MX2007003632A (fr) |
TW (1) | TW200621172A (fr) |
WO (1) | WO2006034826A1 (fr) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009062828A1 (fr) * | 2007-11-12 | 2009-05-22 | Unilever Nv | Composition comestible liquide emballée comprenant des caroténoïdes |
WO2012049534A1 (fr) | 2010-10-14 | 2012-04-19 | Cape Peninsula University Of Technology | Complément alimentaire |
JP2016123289A (ja) * | 2014-12-26 | 2016-07-11 | アサヒビール株式会社 | ルテイン含有飲料 |
EP3015532A4 (fr) * | 2013-06-27 | 2016-07-13 | Bridgestone Corp | Antioxydant, composition de caoutchouc et pneumatique |
US10226422B2 (en) | 2013-01-23 | 2019-03-12 | Bottled Science Limited | Skin enhancing beverage composition |
US11284633B2 (en) | 2015-09-30 | 2022-03-29 | Hills Pet Nutrition, Inc. | Pet food composition for managing non-food allergies |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5909084B2 (ja) * | 2010-12-15 | 2016-04-26 | アークレイ株式会社 | 安定化βクリプトキサンチン含有水およびその用途 |
JP5980934B2 (ja) * | 2012-09-06 | 2016-08-31 | 株式会社ヤクルト本社 | 鉄分およびトコフェロールを強化した発酵乳製品 |
CN104544454A (zh) * | 2014-12-19 | 2015-04-29 | 渤海大学 | 一种海参肽营养粉及其制备方法 |
CN106174466A (zh) * | 2015-05-26 | 2016-12-07 | 帝斯曼知识产权资产管理有限公司 | 一种口服营养组合物 |
CN109198090A (zh) * | 2018-09-27 | 2019-01-15 | 芜湖市好亦快食品有限公司三山分公司 | 藻油dha液体饮料及其制备方法 |
CN111374311A (zh) * | 2018-12-29 | 2020-07-07 | 深圳碳云智能数字生命健康管理有限公司 | 营养素组合物、功能食品及其制备方法和应用 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2648347A1 (fr) * | 1989-06-15 | 1990-12-21 | Sederma Sa | Preparations cosmetiques possedant des proprietes adoucissantes |
FR2773484A1 (fr) * | 1998-01-09 | 1999-07-16 | Pierre Moreau | Nouvelles compositions a effet synergique entre micronutriments et substances d'origine vivante |
WO1999048386A1 (fr) * | 1998-03-24 | 1999-09-30 | Stueckler Franz | Produit a base de substances naturelles |
WO2001000038A1 (fr) * | 1999-06-29 | 2001-01-04 | Xel Herbaceuticals | Preparation effervescente d'extrait de the vert |
EP1120107A1 (fr) * | 2000-01-26 | 2001-08-01 | Johnson & Johnson Consumer France | Complément nutritionnel à base d'huile de pépins de cassis |
US20040052922A1 (en) * | 2000-12-29 | 2004-03-18 | Elvira Pistolesi | Nutritional and therapeutical preparations having antioxidant activity |
US20040081670A1 (en) * | 2001-02-11 | 2004-04-29 | Dariush Behnam | Method for producing an active ingredient concentrate, and an active ingredient concentrate |
-
2005
- 2005-09-23 WO PCT/EP2005/010335 patent/WO2006034826A1/fr active Application Filing
- 2005-09-23 EP EP05793352A patent/EP1814412A1/fr not_active Withdrawn
- 2005-09-23 BR BRPI0516137-1A patent/BRPI0516137A/pt not_active IP Right Cessation
- 2005-09-23 CN CNA2005800326700A patent/CN101026966A/zh active Pending
- 2005-09-23 MX MX2007003632A patent/MX2007003632A/es not_active Application Discontinuation
- 2005-09-26 AR ARP050104044A patent/AR051039A1/es not_active Application Discontinuation
- 2005-09-27 TW TW094133562A patent/TW200621172A/zh unknown
-
2007
- 2007-03-19 CR CR8999A patent/CR8999A/es not_active Application Discontinuation
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2648347A1 (fr) * | 1989-06-15 | 1990-12-21 | Sederma Sa | Preparations cosmetiques possedant des proprietes adoucissantes |
FR2773484A1 (fr) * | 1998-01-09 | 1999-07-16 | Pierre Moreau | Nouvelles compositions a effet synergique entre micronutriments et substances d'origine vivante |
WO1999048386A1 (fr) * | 1998-03-24 | 1999-09-30 | Stueckler Franz | Produit a base de substances naturelles |
WO2001000038A1 (fr) * | 1999-06-29 | 2001-01-04 | Xel Herbaceuticals | Preparation effervescente d'extrait de the vert |
EP1120107A1 (fr) * | 2000-01-26 | 2001-08-01 | Johnson & Johnson Consumer France | Complément nutritionnel à base d'huile de pépins de cassis |
US20040052922A1 (en) * | 2000-12-29 | 2004-03-18 | Elvira Pistolesi | Nutritional and therapeutical preparations having antioxidant activity |
US20040081670A1 (en) * | 2001-02-11 | 2004-04-29 | Dariush Behnam | Method for producing an active ingredient concentrate, and an active ingredient concentrate |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009062828A1 (fr) * | 2007-11-12 | 2009-05-22 | Unilever Nv | Composition comestible liquide emballée comprenant des caroténoïdes |
WO2012049534A1 (fr) | 2010-10-14 | 2012-04-19 | Cape Peninsula University Of Technology | Complément alimentaire |
US10226422B2 (en) | 2013-01-23 | 2019-03-12 | Bottled Science Limited | Skin enhancing beverage composition |
EP3015532A4 (fr) * | 2013-06-27 | 2016-07-13 | Bridgestone Corp | Antioxydant, composition de caoutchouc et pneumatique |
JP2016123289A (ja) * | 2014-12-26 | 2016-07-11 | アサヒビール株式会社 | ルテイン含有飲料 |
US11284633B2 (en) | 2015-09-30 | 2022-03-29 | Hills Pet Nutrition, Inc. | Pet food composition for managing non-food allergies |
Also Published As
Publication number | Publication date |
---|---|
CR8999A (es) | 2007-10-01 |
MX2007003632A (es) | 2007-05-24 |
BRPI0516137A (pt) | 2008-08-26 |
AR051039A1 (es) | 2006-12-13 |
WO2006034826B1 (fr) | 2006-11-09 |
EP1814412A1 (fr) | 2007-08-08 |
CN101026966A (zh) | 2007-08-29 |
TW200621172A (en) | 2006-07-01 |
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