WO2006032697A3 - Parvovirus - Google Patents
Parvovirus Download PDFInfo
- Publication number
- WO2006032697A3 WO2006032697A3 PCT/EP2005/054771 EP2005054771W WO2006032697A3 WO 2006032697 A3 WO2006032697 A3 WO 2006032697A3 EP 2005054771 W EP2005054771 W EP 2005054771W WO 2006032697 A3 WO2006032697 A3 WO 2006032697A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- parvovirus
- capsid protein
- modified
- modified vpl
- vpl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14211—Erythrovirus, e.g. B19 virus
- C12N2750/14222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL05799042T PL1791858T3 (pl) | 2004-09-24 | 2005-09-23 | Zmodyfikowane białko kapsydowe VP1 z parwowirusa B19 |
US11/575,951 US9573979B2 (en) | 2004-09-24 | 2005-09-23 | Modified VP1-capsid protein of parvovirus B19 |
EP05799042A EP1791858B1 (fr) | 2004-09-24 | 2005-09-23 | Proteine de capside vp1 modifiee du parvovirus b19 |
AT05799042T ATE465173T1 (de) | 2004-09-24 | 2005-09-23 | Verändertes vp-1capsidprotein von parvovirus b19 |
DE602005020815T DE602005020815D1 (de) | 2004-09-24 | 2005-09-23 | Verändertes vp-1capsidprotein von parvovirus b19 |
US15/408,485 US20170260239A1 (en) | 2004-09-24 | 2017-01-18 | Modified vp1-capsid protein of parvovirus b19 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04450180.7 | 2004-09-24 | ||
EP04450180 | 2004-09-24 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/575,951 A-371-Of-International US9573979B2 (en) | 2004-09-24 | 2005-09-23 | Modified VP1-capsid protein of parvovirus B19 |
US15/408,485 Division US20170260239A1 (en) | 2004-09-24 | 2017-01-18 | Modified vp1-capsid protein of parvovirus b19 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006032697A2 WO2006032697A2 (fr) | 2006-03-30 |
WO2006032697A3 true WO2006032697A3 (fr) | 2006-05-18 |
Family
ID=35809798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2005/054771 WO2006032697A2 (fr) | 2004-09-24 | 2005-09-23 | Parvovirus |
Country Status (9)
Country | Link |
---|---|
US (2) | US9573979B2 (fr) |
EP (2) | EP2149583B1 (fr) |
AT (1) | ATE465173T1 (fr) |
CY (1) | CY1110185T1 (fr) |
DE (1) | DE602005020815D1 (fr) |
ES (2) | ES2344739T3 (fr) |
PL (1) | PL1791858T3 (fr) |
PT (1) | PT1791858E (fr) |
WO (1) | WO2006032697A2 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090215879A1 (en) * | 2008-02-26 | 2009-08-27 | University Of North Carolina At Chapel Hill | Methods and compositions for adeno-associated virus (aav) with hi loop mutations |
WO2010093784A2 (fr) | 2009-02-11 | 2010-08-19 | The University Of North Carolina At Chapel Hill | Vecteurs viraux modifiés et procédés de fabrication et d'utilisation de ceux-ci |
JP2013529894A (ja) | 2010-04-07 | 2013-07-25 | ノバルティス アーゲー | パルボウイルスb19のウイルス様粒子を生成するための方法 |
EP2446898A1 (fr) * | 2010-09-30 | 2012-05-02 | Laboratorios Del. Dr. Esteve, S.A. | Utilisation de l'hormone de croissance pour améliorer la réponse immunitaire chez des patients immunodéprimés |
WO2012055814A1 (fr) | 2010-10-25 | 2012-05-03 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Composé induisant une accumulation de lbpa pour inhiber la transmission intercellulaire du vih |
EP3332802A1 (fr) | 2011-07-06 | 2018-06-13 | GlaxoSmithKline Biologicals SA | Compositions de combinaisons immunogènes et utilisations de celles-ci |
EP2736921B1 (fr) * | 2011-07-25 | 2018-06-27 | GlaxoSmithKline Biologicals SA | Compositions et procédés d'évaluation de l'immunogénicité fonctionnelle de vaccins contre un parvovirus |
CN116333057A (zh) | 2016-05-13 | 2023-06-27 | 4D分子治疗有限公司 | 腺相关病毒变体衣壳和其使用方法 |
KR20220070075A (ko) | 2017-09-20 | 2022-05-27 | 4디 몰레큘러 테라퓨틱스 아이엔씨. | 아데노-관련 바이러스 변이체 캡시드 및 그 용도 |
CN111770999A (zh) | 2017-11-27 | 2020-10-13 | 4D分子治疗有限公司 | 腺相关病毒变体衣壳和用于抑制血管生成的应用 |
JP2022521025A (ja) | 2019-02-25 | 2022-04-04 | ノバルティス アーゲー | Biettiクリスタリン網膜症を治療するための組成物及び方法 |
JP2022520875A (ja) | 2019-02-25 | 2022-04-01 | ノバルティス アーゲー | Biettiクリスタリン網膜症を治療するための組成物及び方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000030668A2 (fr) * | 1998-11-24 | 2000-06-02 | Tripep Ab | Utilisation de particules de capsides de parvovirus dans l'inhibition de la proliferation et de la migration cellulaire |
WO2003006067A2 (fr) * | 2001-07-10 | 2003-01-23 | Deutsches Krebsforschungszentrum | Compositions comprenant une variante de parvovirus vp1 et une proteine de parvovirus ns1 destinee a induire la cytolyse |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0468520A3 (en) | 1990-07-27 | 1992-07-01 | Mitsui Toatsu Chemicals, Inc. | Immunostimulatory remedies containing palindromic dna sequences |
WO1995026204A1 (fr) | 1994-03-25 | 1995-10-05 | Isis Pharmaceuticals, Inc. | Stimulation immunitaire par des analogues d'oligonucleotides de phosphorothioate |
ATE328890T1 (de) | 1994-07-15 | 2006-06-15 | Univ Iowa Res Found | Immunomodulatorische oligonukleotide |
US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
CO4600681A1 (es) | 1996-02-24 | 1998-05-08 | Boehringer Ingelheim Pharma | Composicion farmaceutica para la modulacion inmunitaria |
EP1537877A3 (fr) | 1996-10-11 | 2005-08-03 | The Regents Of The University Of California | Conjugués polynucléotides immunostimulateurs/molécule immunomodulatrice |
EP1039935A4 (fr) | 1997-02-28 | 2005-04-27 | Univ Iowa Res Found | UTILISATION D'ACIDES NUCLEIQUES CONTENANT DES DINUCLEOTIDES CpG NON METHYLES DANS LE TRAITEMENT DES TROUBLES ASSOCIES AUX LIPOPOLYSACCHARIDES |
EP1005368B1 (fr) | 1997-03-10 | 2009-09-02 | Ottawa Hospital Research Institute | Utilisation d'acides nucléiques contenat un dinucléotide CpG non-methylé combiné avec de l'aluminium en tant qu'adjuvants |
CA2289741A1 (fr) | 1997-05-19 | 1998-11-26 | Merck & Co., Inc. | Adjuvant oligonucleotidique |
US6339068B1 (en) | 1997-05-20 | 2002-01-15 | University Of Iowa Research Foundation | Vectors and methods for immunization or therapeutic protocols |
DE19803453A1 (de) | 1998-01-30 | 1999-08-12 | Boehringer Ingelheim Int | Vakzine |
DE69935507T2 (de) | 1998-04-03 | 2007-12-06 | University Of Iowa Research Foundation | Verfahren und produkte zur stimulierung des immunsystems mittels immunotherapeutischer oligonukleotide und zytokine |
EP1077708A1 (fr) | 1998-05-06 | 2001-02-28 | University Of Iowa Research Foundation | Methodes de prevention et de traitement des parasitoses et maladies associees a l'aide d'oligonucleotides cpg |
AT408721B (de) | 1999-10-01 | 2002-02-25 | Cistem Biotechnologies Gmbh | Pharmazeutische zusammensetzung enthaltend ein antigen |
CA2418854A1 (fr) | 2000-08-17 | 2002-02-21 | Jorg Fritz | Vaccin comprenant au moins un antigene et un peptide antimicrobien a base de cathelicidine ou un derive de ce peptide |
AT410635B (de) | 2000-10-18 | 2003-06-25 | Cistem Biotechnologies Gmbh | Vakzin-zusammensetzung |
-
2005
- 2005-09-23 DE DE602005020815T patent/DE602005020815D1/de active Active
- 2005-09-23 AT AT05799042T patent/ATE465173T1/de active
- 2005-09-23 PL PL05799042T patent/PL1791858T3/pl unknown
- 2005-09-23 US US11/575,951 patent/US9573979B2/en not_active Expired - Fee Related
- 2005-09-23 PT PT05799042T patent/PT1791858E/pt unknown
- 2005-09-23 WO PCT/EP2005/054771 patent/WO2006032697A2/fr active Application Filing
- 2005-09-23 EP EP09174552.1A patent/EP2149583B1/fr not_active Not-in-force
- 2005-09-23 ES ES05799042T patent/ES2344739T3/es active Active
- 2005-09-23 EP EP05799042A patent/EP1791858B1/fr not_active Not-in-force
- 2005-09-23 ES ES09174552.1T patent/ES2556710T3/es active Active
-
2010
- 2010-07-13 CY CY20101100651T patent/CY1110185T1/el unknown
-
2017
- 2017-01-18 US US15/408,485 patent/US20170260239A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000030668A2 (fr) * | 1998-11-24 | 2000-06-02 | Tripep Ab | Utilisation de particules de capsides de parvovirus dans l'inhibition de la proliferation et de la migration cellulaire |
WO2003006067A2 (fr) * | 2001-07-10 | 2003-01-23 | Deutsches Krebsforschungszentrum | Compositions comprenant une variante de parvovirus vp1 et une proteine de parvovirus ns1 destinee a induire la cytolyse |
Non-Patent Citations (4)
Title |
---|
BALLOU W RIPLEY ET AL: "Safety and immunogenicity of a recombinant parvovirus B19 vaccine formulated with MF59C.1.", THE JOURNAL OF INFECTIOUS DISEASES. 15 FEB 2003, vol. 187, no. 4, 15 February 2003 (2003-02-15), pages 675 - 678, XP009062414, ISSN: 0022-1899 * |
DORSCH SIMONE ET AL: "The VP1 unique region of parvovirus B19 and its constituent phospholipase A2-like activity.", JOURNAL OF VIROLOGY. FEB 2002, vol. 76, no. 4, February 2002 (2002-02-01), pages 2014 - 2018, XP009062413, ISSN: 0022-538X * |
GIROD ANNE ET AL: "The VP1 capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivity.", THE JOURNAL OF GENERAL VIROLOGY. MAY 2002, vol. 83, no. Pt 5, May 2002 (2002-05-01), pages 973 - 978, XP009062412, ISSN: 0022-1317 * |
SHIELDS L E ET AL: "IN VITRO HEMATOPOIESIS IS INHIBITED IN HUMANS AND NON-HUMAN PRIMATES BY RECOMBINANT PARVO VIRUS CAPSID", AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY, MOSBY, ST LOUIS, MO, US, vol. 182, no. 1 Part 2, January 2000 (2000-01-01), pages S18, XP000914833, ISSN: 0002-9378 * |
Also Published As
Publication number | Publication date |
---|---|
US20070286870A1 (en) | 2007-12-13 |
CY1110185T1 (el) | 2015-01-14 |
US9573979B2 (en) | 2017-02-21 |
DE602005020815D1 (de) | 2010-06-02 |
EP1791858B1 (fr) | 2010-04-21 |
ATE465173T1 (de) | 2010-05-15 |
WO2006032697A2 (fr) | 2006-03-30 |
EP1791858A2 (fr) | 2007-06-06 |
PL1791858T3 (pl) | 2010-09-30 |
ES2556710T3 (es) | 2016-01-19 |
EP2149583B1 (fr) | 2015-10-28 |
PT1791858E (pt) | 2010-07-26 |
ES2344739T3 (es) | 2010-09-06 |
US20170260239A1 (en) | 2017-09-14 |
EP2149583A1 (fr) | 2010-02-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2006032697A3 (fr) | Parvovirus | |
WO2006018652A3 (fr) | Peptide | |
WO2007076032A3 (fr) | Compositions et procédés de production d'une composition | |
WO2005012347A3 (fr) | Nouveaux derives de l'insuline | |
WO2003012105A3 (fr) | Isoforme de facteur de croissance | |
WO2006087550A3 (fr) | Peptides fixant les amyloides, produits analogues et applications de ces peptides | |
WO2004111216A3 (fr) | Variantes genetiques de la phospholipase | |
WO2006017355A3 (fr) | Variants d'aprotinine ameliores | |
EP1344827A3 (fr) | Protéines antigel de basidiomycètes | |
WO2007093848A3 (fr) | Nouveaux polypeptides purifiés issus de helicobacter pylori | |
WO2005039626A3 (fr) | Procedes et compositions a utiliser pour le traitement des diabetes | |
WO2008047370A3 (fr) | Compositions et méthodes permettant d'induire l'angiogenèse | |
WO2006096690A3 (fr) | Compositions et procedes d'inhibition de la signalisation de proteine g | |
WO2007085728A3 (fr) | Composition comprenant plusieurs toxines botuliques | |
WO2005000862A3 (fr) | Reactifs et procedes pour former des liaisons disulfure et pour glycosyler des proteines | |
WO2010026219A3 (fr) | Nouveaux facteurs de réponse à l’éthylène de la tomate et leurs utilisations | |
WO2005072766A3 (fr) | Peptides se liant aux proteines hsp90 | |
WO2006043060A3 (fr) | Proteine contenant le domaine mam | |
SG146640A1 (en) | Isolated photoprotein mtclytin, and use thereof | |
WO2003082897A3 (fr) | Fragments de peptides actifs synthetiques | |
WO2002062964A3 (fr) | Variants d'amine oxydase ap1 | |
WO2007073845A3 (fr) | Nouveau polypeptide presentant une activite d'esterase, esterase recombinee et leur utilisation | |
WO2006044294A3 (fr) | Analogues de la proteine humaine c | |
WO2006122650A3 (fr) | Photoproteine isolee aqdecay et utilisation | |
WO2007144492A3 (fr) | Peptides a activite anti-proliferative |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV LY MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU LV MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2005799042 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 11575951 Country of ref document: US |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
WWP | Wipo information: published in national office |
Ref document number: 2005799042 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 11575951 Country of ref document: US |