WO2006021335A3 - Peptidmischung aus peptiden mit einem molekulargewicht vom 1000-5000 dalton - Google Patents

Peptidmischung aus peptiden mit einem molekulargewicht vom 1000-5000 dalton Download PDF

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Publication number
WO2006021335A3
WO2006021335A3 PCT/EP2005/008805 EP2005008805W WO2006021335A3 WO 2006021335 A3 WO2006021335 A3 WO 2006021335A3 EP 2005008805 W EP2005008805 W EP 2005008805W WO 2006021335 A3 WO2006021335 A3 WO 2006021335A3
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WO
WIPO (PCT)
Prior art keywords
peptide mixture
peptides
dalton
molecular weight
immune system
Prior art date
Application number
PCT/EP2005/008805
Other languages
English (en)
French (fr)
Other versions
WO2006021335A2 (de
Inventor
Guenther Boehm
Christopher Beermann
Gilda Georgi
Bernd Stahl
Joachim Schmitt
Nadine Bock
Soerge Kelm
Original Assignee
Nutricia Nv
Guenther Boehm
Christopher Beermann
Gilda Georgi
Bernd Stahl
Joachim Schmitt
Nadine Bock
Soerge Kelm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nutricia Nv, Guenther Boehm, Christopher Beermann, Gilda Georgi, Bernd Stahl, Joachim Schmitt, Nadine Bock, Soerge Kelm filed Critical Nutricia Nv
Priority to US11/660,595 priority Critical patent/US20080096794A1/en
Priority to EP05777789A priority patent/EP1799053A2/de
Publication of WO2006021335A2 publication Critical patent/WO2006021335A2/de
Publication of WO2006021335A3 publication Critical patent/WO2006021335A3/de

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00Working-up of proteins for foodstuffs
    • A23J3/30Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/346Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of vegetable proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00Working-up of proteins for foodstuffs
    • A23J3/30Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/341Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
    • A23J3/343Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
    • A23J3/344Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins of casein
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/18Peptides; Protein hydrolysates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20Milk; Whey; Colostrum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/168Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Nutrition Science (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pediatric Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Die Erfindung betrifft die Verwendung einer Peptidmischung aus Peptiden mit einem Molekulargewicht von 1000 bis 5000 Dalton zur Prävention und/oder Behandlung von Tumorerkrankungen, von Erkrankungen, welche mit einer Entwicklungsstörung des Immunsystems assoziiert sind, von Erkrankungen des Immunsystems, von Autoimmunreaktionen, von Allergien und von Entzündungen beim Menschen, eine Proteinkomponente, welche eine derartige Peptidmischung enthält, und eine diese Peptidmischung enthaltene Formelnahrung. Die Peptide werden vorzugsweise aus für Nahrungszwecke geeigneten, nicht­humanen Proteinen erhalten, insbesondere durch die enzymatische oder hydrolytische Spaltung dieser Proteine.
PCT/EP2005/008805 2004-08-20 2005-08-12 Peptidmischung aus peptiden mit einem molekulargewicht vom 1000-5000 dalton WO2006021335A2 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US11/660,595 US20080096794A1 (en) 2004-08-20 2005-08-12 Peptide Mixture From Peptides Having A Molecular Weight Of from 1000 To 5000 Dalton
EP05777789A EP1799053A2 (de) 2004-08-20 2005-08-12 Peptidmischung aus peptiden mit einem molekulargewicht vom 1000-5000 dalton

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004040452A DE102004040452A1 (de) 2004-08-20 2004-08-20 Peptidgemisch
DE102004040452.6 2004-08-20

Publications (2)

Publication Number Publication Date
WO2006021335A2 WO2006021335A2 (de) 2006-03-02
WO2006021335A3 true WO2006021335A3 (de) 2006-04-20

Family

ID=35613806

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/008805 WO2006021335A2 (de) 2004-08-20 2005-08-12 Peptidmischung aus peptiden mit einem molekulargewicht vom 1000-5000 dalton

Country Status (5)

Country Link
US (1) US20080096794A1 (de)
EP (1) EP1799053A2 (de)
CN (1) CN101043900A (de)
DE (1) DE102004040452A1 (de)
WO (1) WO2006021335A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0621481A2 (pt) * 2006-03-23 2011-12-13 Nestec Sa suplemento nutricional de alta caloria
DE102008062136B4 (de) * 2008-12-16 2012-05-03 Kamamed Ug Pharmazeutische Zusammensetzung auf Basis von Peptid aus Kamelmilch
WO2010099821A1 (en) * 2009-03-04 2010-09-10 Nestec S.A. Oligosaccharide ingredient
BRPI1013708B1 (pt) * 2009-04-02 2020-01-14 Novozymes As processo para preparar um hidrolisado de proteína à base de leite
ES2524067T3 (es) * 2009-12-04 2014-12-03 Mjn U.S. Holdings Llc Formulación nutricional que comprende un hidrolizado que contiene péptidos de leche de vaca y/o péptidos derivados del mismo para la inducción de tolerancia
US20130243904A1 (en) 2010-08-24 2013-09-19 Abbott Laboratories Nutritional products having improved organoleptic properties
US9345727B2 (en) 2013-03-15 2016-05-24 Mead Johnson Nutrition Company Nutritional compositions containing a peptide component and uses thereof
US9289461B2 (en) 2013-03-15 2016-03-22 Mead Johnson Nutrition Company Reducing the risk of autoimmune disease
US9352020B2 (en) 2013-03-15 2016-05-31 Mead Johnson Nutrition Company Reducing proinflammatory response
US9345741B2 (en) 2013-03-15 2016-05-24 Mead Johnson Nutrition Company Nutritional composition containing a peptide component with adiponectin simulating properties and uses thereof
US9138455B2 (en) 2013-03-15 2015-09-22 Mead Johnson Nutrition Company Activating adiponectin by casein hydrolysate
US8889633B2 (en) 2013-03-15 2014-11-18 Mead Johnson Nutrition Company Nutritional compositions containing a peptide component with anti-inflammatory properties and uses thereof
CN110041424A (zh) * 2019-03-22 2019-07-23 新疆大学 一种驼乳乳清抗肿瘤活性蛋白及其制备方法和应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135592A1 (de) * 1983-02-02 1985-04-03 Kyowa Hakko Kogyo Co., Ltd. Dna-synthese verhindernde substanz
EP0626177A2 (de) * 1993-05-28 1994-11-30 Abbott Laboratories Nahrung für mit HIV infizierte Menschen
WO2004069265A1 (en) * 2003-02-07 2004-08-19 Campina B.V. Use of tryptophan rich peptides
WO2004113378A2 (en) * 2003-06-16 2004-12-29 Hannah Research Institute Control of lactation and peptides therefore

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5229136A (en) * 1992-05-21 1993-07-20 Clintec Nutrition Co. Low caloric density enteral formulation designed to reduce diarrhea in tube-fed patients
US5472952A (en) * 1993-03-18 1995-12-05 Bristol-Myers Squibb Company Partially hydrolyzed pectin in nutritional compositions
US5330972A (en) * 1993-05-28 1994-07-19 Abbott Laboratories Method of impeding apoptosis of CD4 cells in persons infected with human immunodeficiency virus
US5906982A (en) * 1997-03-31 1999-05-25 Abbott Laboratories Nutritional formulations containing Lacto-N-neoTetraose
US6808736B2 (en) * 2001-06-07 2004-10-26 Nestec S.A. Soy hydrolysate based nutritional formulations
US7867541B2 (en) * 2003-04-14 2011-01-11 Mead Johnson Nutrition Company Compositions and methods of formulation for enteral formulas containing sialic acid

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135592A1 (de) * 1983-02-02 1985-04-03 Kyowa Hakko Kogyo Co., Ltd. Dna-synthese verhindernde substanz
EP0626177A2 (de) * 1993-05-28 1994-11-30 Abbott Laboratories Nahrung für mit HIV infizierte Menschen
WO2004069265A1 (en) * 2003-02-07 2004-08-19 Campina B.V. Use of tryptophan rich peptides
WO2004113378A2 (en) * 2003-06-16 2004-12-29 Hannah Research Institute Control of lactation and peptides therefore

Also Published As

Publication number Publication date
WO2006021335A2 (de) 2006-03-02
US20080096794A1 (en) 2008-04-24
DE102004040452A1 (de) 2006-02-23
EP1799053A2 (de) 2007-06-27
CN101043900A (zh) 2007-09-26

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