WO2005084835A1 - Dispositif pour conduire de l'air et reguler la pression dans un isolateur, comprenant une chambre de travail qui est protegee par rapport a l'environnement exterieur - Google Patents

Dispositif pour conduire de l'air et reguler la pression dans un isolateur, comprenant une chambre de travail qui est protegee par rapport a l'environnement exterieur Download PDF

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Publication number
WO2005084835A1
WO2005084835A1 PCT/CH2005/000073 CH2005000073W WO2005084835A1 WO 2005084835 A1 WO2005084835 A1 WO 2005084835A1 CH 2005000073 W CH2005000073 W CH 2005000073W WO 2005084835 A1 WO2005084835 A1 WO 2005084835A1
Authority
WO
WIPO (PCT)
Prior art keywords
air
supply
plenum
control element
working chamber
Prior art date
Application number
PCT/CH2005/000073
Other languages
German (de)
English (en)
Inventor
Thomas Neuschwander
Volker Sigwarth
Original Assignee
Skan Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Skan Ag filed Critical Skan Ag
Priority to DE202005020907U priority Critical patent/DE202005020907U1/de
Publication of WO2005084835A1 publication Critical patent/WO2005084835A1/fr

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B15/00—Preventing escape of dirt or fumes from the area where they are produced; Collecting or removing dirt or fumes from that area
    • B08B15/02—Preventing escape of dirt or fumes from the area where they are produced; Collecting or removing dirt or fumes from that area using chambers or hoods covering the area
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B15/00—Preventing escape of dirt or fumes from the area where they are produced; Collecting or removing dirt or fumes from that area
    • B08B15/02—Preventing escape of dirt or fumes from the area where they are produced; Collecting or removing dirt or fumes from that area using chambers or hoods covering the area
    • B08B15/023—Fume cabinets or cupboards, e.g. for laboratories
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B15/00—Preventing escape of dirt or fumes from the area where they are produced; Collecting or removing dirt or fumes from that area
    • B08B15/02—Preventing escape of dirt or fumes from the area where they are produced; Collecting or removing dirt or fumes from that area using chambers or hoods covering the area
    • B08B15/026—Boxes for removal of dirt, e.g. for cleaning brakes, glove- boxes
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F3/00—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems
    • F24F3/12—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling
    • F24F3/16—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling by purification, e.g. by filtering; by sterilisation; by ozonisation
    • F24F3/163—Clean air work stations, i.e. selected areas within a space which filtered air is passed

Definitions

  • the invention relates to an isolator with a working chamber which is supplied with cleaned, low-turbulence displacement flow.
  • a product handled in the working chamber is to be protected against contamination from the surroundings of the isolator, e.g. when performing sterility tests on pharmaceutical products.
  • the working chamber is operated hermetically with a pressure that is higher than the environment.
  • toxically contaminated products are handled in the working chamber, whereby no harmful substances are allowed to get into the environment from the chamber, e.g. when filling toxins or in research experiments.
  • the working chamber is placed under a pressure which is lower than that of the surroundings.
  • the invention is concerned with an arrangement for regulating the pressure in the working chamber and for guiding the air throughout the isolator.
  • an isolator is a housing that is tightly sealed from the environment, in which a working chamber is divided, in which products are handled - for example, packaged, filled or decontaminated.
  • a working chamber is divided, in which products are handled - for example, packaged, filled or decontaminated.
  • the manual access to the working chamber takes place via gloves attached to the front window of the isolator in cuffs, in which the operator engages from outside and enter
  • a cleaned air flow is continuously passed through the working chamber.
  • a low-turbulence, quasi-laminar air flow is particularly advantageous in order to largely avoid turbulence.
  • this requires a relatively high air throughput through the working chamber and thus a separate fan as a circulating air blower.
  • the low-turbulence air flow is returned to the circulation circuit for supplying fresh air into the isolator or for removing air from the isolator.
  • At least one additional fan is required, often also one fan for drawing in fresh air and another for removing partially used air mixture. Insulators are therefore typically equipped with three fans and a control device provided for this purpose.
  • An insulator constructed in this way is disclosed, for example, in GB 2 286 986 A, which has an inner working chamber and a jacket-shaped chamber that surrounds it and delimits the insulator from the outside. mer has.
  • the pressure in the jacket chamber is kept lower than the external ambient pressure as well as lower than the pressure in the inner working chamber. Contamination that gets into the jacket chamber from the working chamber and, in the event of a leak, from the outside environment is removed by the air circulating in it and air filters are supplied.
  • Insulators with three separate fans for the supply of fresh air, the circulating air circuit and the removal of partially used air mixture have also been marketed by the applicant for years, as documented in the company documents, for example: "Skan Isolator Systems", IT / d / 6-97; “Directive on design guidelines for the design and construction of isolator systems", page 2 of 2, 005/98, printed note 3.08.1998 / RSch; both Skan AG, CH-4123 Allschwil / Switzerland.
  • the object of the present invention is to propose an isolator with a reduced outlay in terms of apparatus, with a high supply and exhaust air rate to be achieved. It is also important to be able to set a positive and negative pressure difference between the working chamber and the outside environment. Even with abrupt pressure disturbances, stable pressure conditions should be maintained.
  • the arrangement for air flow and pressure control in an isolator initially has a working chamber with at least one access for introducing and discharging the product to be treated.
  • a circulating air filter adjoins the working chamber, which is preferably preceded by a controllable fan. be-
  • a suction area facing away from the recirculating air plenum is on the flow side in front of the fan, which is intended for conveying air through the recirculating air filter in the direction of the working chamber.
  • a return air duct extends from the working chamber to the intake area.
  • a supply line opens into the suction area of the isolator from the external environment.
  • a derivative emerges from the insulator into the external environment.
  • the suction area is connected to the discharge only in terms of flow via the fan and the recirculating air plenum, but is otherwise, at least in principle, delimited in a gas-tight manner with respect to the discharge, the discharge coming from the recirculating air plenum. Furthermore, for the removal of air from the working chamber, this is at least in principle only connected to the suction area, which is done via the return air duct.
  • a return air part e.g. a flap is arranged in the return air duct to influence the flow resistance.
  • the return air control element can be provided with a return air control drive.
  • first supply air control element in the supply line, e.g. an orifice which serves to influence the flow resistance and is connected to a first supply air actuator.
  • a first exhaust air control element e.g. an orifice, arranged, which serves to influence the flow resistance and is connected to a first exhaust air actuator.
  • a supply air filter is used in the supply line, which can have a supply air plenum.
  • a second supply air control element which is used for gas-tight shut-off and is connected to a second supply air actuator, is placed in the supply line of the supply air filter in the direction of the external environment.
  • an exhaust air filter which can be provided with a plenum arranged on both sides, and for cleaning the from the recirculating air plenum into the air to be discharged from the outside environment.
  • a second exhaust air control element is placed in front of the exhaust air filter in the direction of the external environment, which serves for gas-tight shut-off and is connected to a second exhaust air control drive.
  • the first supply air control element is placed in front of the second supply air control element in the direction of the external environment and is connected to a first supply air control drive.
  • the first exhaust air control element is placed in front of the second exhaust air control element in the direction of the external environment and is connected to a first exhaust air control drive.
  • a parallel supply line preferably opens into the supply line between the first supply air control element and the supply air plenum, this parallel supply line also opening directly into the intake area.
  • a third supply air control element connected to a third supply air actuator, e.g. a valve.
  • a parallel duct preferably branches off from the duct between the second exhaust air control element and the adjacent exhaust air filter, or the parallel duct goes directly from the recirculating air plenum.
  • a third exhaust air control element e.g. a valve is used, which is connected to a third exhaust air actuator.
  • a short-circuit line extends between the supply line and the discharge line, which on the one hand opens between the second supply air control element and the supply air plenum and on the other hand between the second exhaust air control element and the adjacent plenum.
  • a fourth short-circuit actuator e.g. a valve. If a parallel supply line and a parallel discharge line are present, the connections of the short-circuit line are preferably on the one hand between the junction of the parallel supply line in the supply line and the supply air plenum, and on the other hand between the discharge point of the parallel supply line in the discharge line and the adjacent exhaust air plenum.
  • Means for regulating the pressure in the working chamber are provided on the isolator.
  • a pressure sensor is positioned in the working chamber, which is connected to a pressure regulator.
  • the pressure regulator acts on the first exhaust air control element in the discharge line and / or on the first supply air control element in the supply line, or the pressure regulator acts on the return air control element located in the return air duct.
  • the suction area is located above the circulating air plenum and the working chamber is below the circulating air plenum. Access to the return air duct is provided in the lower area of the working chamber.
  • guide elements can be attached in the circulating air plenum.
  • the insulator represents a housing that is delimited from the external environment.
  • the suction area and the recirculating air plenum are delimited from one another by a recirculating air plenum wall.
  • the working chamber has a partition, behind which the return air duct extends, which is separated from the outside by the rear wall of the housing.
  • Figure 1A a schematic representation of the isolator according to the invention, in front view;
  • Figure 1 B the representation according to Figure 1A, in side view;
  • Figure 2A the insulator according to Figure 1A in more detailed construction, in front view
  • Figure 2B the representation according to Figure 2A, with additional decontamination system, in side view;
  • FIG. 3A - a functional diagram of the isolator in the basic version
  • FIG. 3B - a functional diagram of the isolator according to FIG. 3A, with additional parallel feed and discharge as well as a further actuator in the feed and discharge; and FIG. 3C - a functional diagram of the isolator according to FIG. 3B, with an additional short-circuit line between the supply and discharge line and measurement of the efficiency of the air filters present.
  • FIGS. 1A to 2B The working chamber 14 provided for the treatment of products under clean room conditions is located in the interior of a housing 10, which limits the insulator 1 from the external environment U.
  • the working chamber 14 has at least one access (not shown here) for introducing and discharging the product to be treated.
  • the circulating air zone 13 comprises the suction area 130, the fan 4 lying below a circulating air plenum wall 135 and the circulating air plenum 131 surrounding the fan 4.
  • the circulating air filter 5 preferably an H EPA air filter - separates the working chamber 14 from the circulating air plenum 131.
  • the entire circulating air zone 13 is enclosed by the upper housing part 11.
  • the fan 4 conveys air from the intake area 130 into the recirculating air plenum 131 and further through the recirculating air filter 5 into the working chamber 14.
  • the fan 4 sits on a base plate 40, from which guide plates 41 extend obliquely upwards on both sides, which guide the exiting the side of the fan 4 Forcing air into a downward, low-turbulence displacement flow - also known as laminar air flow.
  • the working chamber 14 is enclosed by the lower housing part 12, the bottom 120 of which limits the working chamber 14 at the bottom.
  • the working chamber 14 has a partition 126, behind which the return air duct 2 extends, which the rear wall 125 divides from the external environment U.
  • the access 20 to the return air duct 2 is located in the lower region of the working chamber 14, the return air duct 2 running upwards and opening into the suction region 130 via the outlet 21 located at the level of the circulating air filter 5.
  • a return air control element 22 e.g. a flap arranged. If the insulator 1 is designed for the operation of the front window 121, gloves 123 fastened in the cuffs 122 are present as a manual intervention 124 in the working chamber 14. An operator 3 working on the isolator 1 can thus reach into the working chamber 14 with his arms 30, protected by the gloves 123, and grasp products to be treated.
  • a supply line 63 for supplying fresh air opens into the suction area 130 from the outer environment U, and a discharge line 73 extends from the insulator 1 as an outlet for partially polluted air - A mixture of fresh air returned and added from the working chamber 14 - into the outer environment U.
  • a supply air filter 60 with a supply air plenum 61 above is inserted into the supply line 63 for cleaning the fresh air flowing from the outer environment U into the suction area 130 ,
  • a second supply air control element 64 is placed in front of the supply air filter 60 in the direction of the external environment U, which serves for gas-tight shut-off and is connected to a second supply air control drive 65.
  • a second exhaust air control element 74 is placed in the discharge line 73 in front of the exhaust air filter 70 in the direction of the external environment U, which serves for gas-tight shut-off and is connected to a second exhaust air control drive 75.
  • a first exhaust air control element 76 for example an orifice, is placed in front of the adjacent second exhaust air control element 74 in the direction of the external environment U, which serves to influence the flow resistance and is connected to an associated first exhaust air control drive 77.
  • the decontamination system 132 In the interior of the isolator 1, preferably in the suction area 130, there is a known decontamination system 132 with an evaporator 133, with which the isolator 1 is sterilized in a conventional manner - in special working processes together with the introduced product.
  • a suitable decontamination agent such as e.g. Hydrogen peroxide supplied.
  • the supply and exhaust air lines 63, 73 are sealed gas-tight by the respective second supply air or exhaust air control element 64, 74.
  • the suction area 130 is connected to the discharge line 73 only via the fan 4 and the recirculating air plenum 131, but is otherwise, at least in principle, delimited in a gas-tight manner with respect to the discharge line 73, which comes directly from the recirculating air plenum 131. Furthermore, to remove air from the working chamber 14, the latter is at least in principle only connected to the suction area 130, namely through the return air duct 2.
  • the principle of air flow and pressure control in isolator 1 is explained on the basis of this functional diagram.
  • the circulation of the air is achieved by the fan 4 first drawing air from the suction region 130 and conveying it into the recirculating air plenum 131.
  • the air is forced through the air recirculation filter i into the working chamber U4 from the air recirculation plenum 131 and flows through it downwards, preferably laminar, and passes through the access 20 into the return air duct 2, in which the return air part 22 sits.
  • the return air duct 2 the air flows upward and returns to the suction area 130 via the outlet 21.
  • the fan 4 is driven by the fan motor 42, which feeds the power supply 43. To protect against overheating, the fan motor 42 is provided with a temperature cutoff 44.
  • the flow resistance of the return air duct 2 can be set by means of the return air control element 22.
  • An increase in the flow resistance causes a reduction in the pressure in the suction area 130, so that an increased amount of air is drawn from the external environment U via the supply line 63, through the first supply air control element 66, into the supply air plenum 61 and through the supply air filter 60 into the suction area 130.
  • air is backed up in the working chamber 14 due to the greater flow resistance in the return air duct 2.
  • the amount of air in the working chamber 14 increases and the pressure prevailing therein increases.
  • an increased amount of air is introduced via the fan 4 into the recirculating air plenum 131 and from there via the duct 134 and the exhaust air unit 7 into the environment U expelled. This compensates for the positive pressure disturbance.
  • a pressure sensor 80 is arranged in the working chamber 14 and is connected to a pressure regulator 8, a signal line 81 extending from the pressure regulator 8 to the first exhaust air actuator 77 in the exhaust air unit 7.
  • a predetermined pressure setpoint in the working chamber 14 can be kept constant by the first exhaust air control element 76, e.g. an iris diaphragm is opened less so that a smaller amount of air can flow away.
  • the first exhaust air control element 76 opens further when the pressure is exceeded, so that the exhaust air throughput increases.
  • a second supply air control element 64 is now inserted between the already existing first supply air control element 66 and the supply air plenum 61 in the supply line 63, which serves for gas-tight shut-off and is connected to a second supply air control drive 65.
  • a second exhaust air control element 74 is inserted in the exhaust air unit 7, between the already existing first exhaust air control element 76 and the upper exhaust air plenum 72 in the discharge line 73, which serves for gas-tight shut-off and is connected to an associated second exhaust air control drive 75.
  • a parallel supply line 68 is provided in the supply air unit 6, which opens into the supply line ⁇ 3 between the second supply air control element 64 and the supply air passage 81.
  • the ParaHelzuloitung iS is a third ZulL-f-sfeliorgan SD, e.g. a Valve connected to a third 690 supply air actuator.
  • a parallel duct 78 is present in the exhaust unit 7, which leads into the duct 73 between the second exhaust air actuator 74 and the adjacent upper plenum 72.
  • a third exhaust air control element 79 for example a valve, which is connected to a third exhaust air control drive 790, is built into the parallel line 78.
  • the first exhaust air control element 76 has an inert characteristic and serves to counteract the drift of a regulated state independently of abrupt pressure disturbances. If one wants to set a pressure in the working chamber 14 that is higher than the external environment U, as + ⁇ p, the first exhaust air control element 76 in the exhaust air unit 7 is used for control. On the other hand, if there is a pressure in the working chamber 14 that is lower than - ⁇ p compared to the external environment U, the first supply air control element 66 in the supply air unit 6 is used for control.
  • a second signal line 82 extends from the pressure regulator 8 to the first supply air actuator 67 in the supply air unit 7.
  • the return air control element 22 is now provided with a return air actuator 23 which is connected to the pressure regulator 8 via a third signal line 83 is.
  • the link shown here of all three actuators 23, 67, 77 with the pressure regulator 8 via three associated signal lines 81, 82, 83 is a maximum interconnection.
  • one of the two actuators 23, 67 alone or an arbitrary combination of two could alternatively be used Connect three actuators 23, 67, 77 to the pressure regulator 8 via the associated signal lines 81, 82, 83.
  • a short-circuit line 90 used in the supply air filter test 61 runs between the supply line 63 and the discharge line 73.
  • the short-circuit line 90 opens into the supply line 63 and the connection point between the parallel supply line 68
  • the short-circuit line opens 90 between the connection point of the parallel duct 78 into the supply line 73 and the upper exhaust air plenum 72.
  • a fourth short-circuit actuator 91 for example a valve, is arranged in the short-circuit line 90.
  • a suitable aerosol known per se is first supplied to the air flow through the access ports 92.
  • a reference sample for determining the aerosol concentration of the air streams before passing through the respective circulating air filter 5, supply air filter 60 or exhaust air filter 70 is taken from the outlet connection 93.
  • the aerosol concentration through which the filters 5, 60, 70 passed is determined again at the measuring points 94 Air flows as a result sample.
  • the effectiveness of the circulating air filter 5, supply air filter 60 and exhaust air filter 70 tested results from the comparison between the reference sample and the result sample.
  • the second supply air control element 64 and the second and third exhaust air control elements 74, 79 are closed in the supply air unit 6 and exhaust air unit 7 before the fan 4 is switched on.
  • the third supply air actuator 69 remains open. If the specified test pressure has been set in the isolator 1, the fan 4 switches off, at the same time the third supply air actuator 69 is closed and pressure monitoring begins. The pressure drop over time is a measure of the tightness of the isolator 1.
  • the second supply and exhaust air control elements 64, 74 as well as the first supply and exhaust air control elements 64, 74 are opened to the already open third supply air control element 69 and open third exhaust air control element 79, which are arranged in the parallel supply line 68 or parallel discharge line 78 Exhaust air control elements 66.76, which are installed in the supply and discharge lines 63.73.

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Ventilation (AREA)

Abstract

L'invention concerne un dispositif pour conduire de l'air et réguler la pression dans un isolateur (1), comprenant une chambre de travail (14), qui est adjacente à un filtre à air ambiant (5) en amont duquel est placé un ventilateur (4). Une chambre à air ambiant (131) est disposée entre le ventilateur (4) et le filtre à air ambiant (5). Une zone d'aspiration (130) est disposée avant le ventilateur (4), côté écoulement, et sert à transporter l'air à travers le filtre à air ambiant (5) vers la chambre de travail (14) à partir de laquelle une conduite d'air de retour (2) s'étend vers la zone d'aspiration (130). Un logement (10) délimite l'isolateur (1) par rapport à l'environnement extérieur (U), une conduite d'amenée (63) menant de l'environnement extérieur à la zone d'aspiration (130). Une conduite d'évacuation (73) sort de la chambre à air ambiant (131) de l'isolateur (1). La zone d'aspiration (130) est reliée par écoulement avec la conduite de sortie (73), uniquement par l'intermédiaire du ventilateur (4) et de la chambre à air ambiant (131), et est par ailleurs délimitée de manière étanche aux gaz par rapport à la conduite de sortie (73). Pour évacuer l'air se trouvant dans la chambre de travail (14), cette dernière est reliée avec la zone d'aspiration (130) uniquement par l'intermédiaire de la conduite d'air de retour (2). De manière particulièrement avantageuse, le dispositif selon l'invention présente une complexité structurale réduite et permet simultanément d'obtenir des rapports de pression et d'écoulement stables.
PCT/CH2005/000073 2004-03-04 2005-02-10 Dispositif pour conduire de l'air et reguler la pression dans un isolateur, comprenant une chambre de travail qui est protegee par rapport a l'environnement exterieur WO2005084835A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE202005020907U DE202005020907U1 (de) 2004-03-04 2005-02-10 Anordnung zur Luftführung und Druckregelung in einem Isolator mit einer gegen die äußere Umgebung abgeschirmten Arbeitskammer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH3602004 2004-03-04
CH360/04 2004-03-04

Publications (1)

Publication Number Publication Date
WO2005084835A1 true WO2005084835A1 (fr) 2005-09-15

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ID=34916948

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Application Number Title Priority Date Filing Date
PCT/CH2005/000073 WO2005084835A1 (fr) 2004-03-04 2005-02-10 Dispositif pour conduire de l'air et reguler la pression dans un isolateur, comprenant une chambre de travail qui est protegee par rapport a l'environnement exterieur

Country Status (2)

Country Link
DE (1) DE202005020907U1 (fr)
WO (1) WO2005084835A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106393181A (zh) * 2016-09-13 2017-02-15 中国人民解放军军事医学科学院卫生装备研究所 生物安全型手套箱式隔离器

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3895570A (en) * 1973-09-27 1975-07-22 Baker Company Inc Air-insulated work station
US5380244A (en) * 1993-05-24 1995-01-10 Forma Scientific, Inc. Safety cabinet
GB2286986A (en) * 1994-01-31 1995-09-06 Mdh Ltd Isolator and method of operating it
GB2309918A (en) * 1996-02-10 1997-08-13 Medical Air Tech Ltd Microbiological safety cabinet
US5711705A (en) * 1995-05-25 1998-01-27 Flanders Filters, Inc. Isolation work station

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3895570A (en) * 1973-09-27 1975-07-22 Baker Company Inc Air-insulated work station
US5380244A (en) * 1993-05-24 1995-01-10 Forma Scientific, Inc. Safety cabinet
GB2286986A (en) * 1994-01-31 1995-09-06 Mdh Ltd Isolator and method of operating it
US5711705A (en) * 1995-05-25 1998-01-27 Flanders Filters, Inc. Isolation work station
GB2309918A (en) * 1996-02-10 1997-08-13 Medical Air Tech Ltd Microbiological safety cabinet

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106393181A (zh) * 2016-09-13 2017-02-15 中国人民解放军军事医学科学院卫生装备研究所 生物安全型手套箱式隔离器
CN106393181B (zh) * 2016-09-13 2018-12-25 中国人民解放军军事医学科学院卫生装备研究所 生物安全型手套箱式隔离器

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