WO2005082141A1 - Formulation chimique agricole - Google Patents

Formulation chimique agricole Download PDF

Info

Publication number
WO2005082141A1
WO2005082141A1 PCT/JP2004/002274 JP2004002274W WO2005082141A1 WO 2005082141 A1 WO2005082141 A1 WO 2005082141A1 JP 2004002274 W JP2004002274 W JP 2004002274W WO 2005082141 A1 WO2005082141 A1 WO 2005082141A1
Authority
WO
WIPO (PCT)
Prior art keywords
oil
pesticide
weight
parts
water
Prior art date
Application number
PCT/JP2004/002274
Other languages
English (en)
Japanese (ja)
Inventor
Kazuteru Ogawa
Tamotu Suzuki
Original Assignee
Nippon Kayaku Kabushiki Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kayaku Kabushiki Kaisha filed Critical Nippon Kayaku Kabushiki Kaisha
Priority to PCT/JP2004/002274 priority Critical patent/WO2005082141A1/fr
Publication of WO2005082141A1 publication Critical patent/WO2005082141A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels

Definitions

  • the present invention relates to a pesticide formulation and a method of spraying a pesticide, which increase the basic activity of a drug and enhance the effect on drug-resistant pests.
  • a wide variety of preparations that enhance insecticidal and herbicidal effects by adding animal and vegetable oils and / or mineral oils to agricultural chemical preparations have been widely studied.
  • Japanese Patent Publication No. 44-17400 discloses a mixture of hydrocarbon organic solvents, chlorinated hydrocarbon organic solvents, animal and vegetable oils and fatty acid esters mixed with phenol derivatives and resins.
  • Japanese Patent Application Laid-Open No. Sho 62-1996 / 2002 has studied and implemented granules prepared by impregnating vegetable oil in which a pesticidal component is mixed with a granular carrier. ing.
  • oil-based suspension preparations mainly composed of animal and vegetable oils and / or mineral oils have been studied as a method for enhancing the herbicidal effect (Japanese Patent Application Laid-Open (JP-A) No. 1-110605; Japanese Patent Application Laid-Open Nos. Hei 4-2-1611, Heisei 4-2-1613, Hei 6-56 02, Hei 6-40 823, Hei 6-340 509, Hei 7 — 3 3 6 1 2, Canadian Patent 9 8 7 7 6 (1 9 7 5)).
  • a pesticide formulation containing an active ingredient and an oil is dropped 100/1 onto a slide glass, the diluting solvent is evaporated, then diluted to a concentration at which oil droplets are formed, and sprayed.
  • Pesticide spraying method
  • a pesticide spraying method comprising: dropping a pesticide formulation containing a pesticide active ingredient and an oil component onto a slide glass, diluting the oil to a concentration at which the oil droplets are formed when water is evaporated, and spraying.
  • FIG. 1 is a copy of a micrograph showing typical oil droplet formation in a formulation of the invention.
  • FIG. 2 is a photomicrograph copy of Example 5 showing another typical oil droplet formation in a formulation of the invention.
  • FIG. 3 is a copy of an enlarged view of part A in FIG.
  • FIG. 4 is a gopy of a micrograph in Example 5.
  • FIG. 5 is a copy of a micrograph of Comparative Example 2 which is a general conventional preparation.
  • the agricultural chemical formulation of the present invention contains an active ingredient of an agricultural chemical and an oil, and when a diluted solution diluted with water to a spray concentration is dropped on a slide glass and air-dried, at least one part of the oil, preferably most of the oil Form oil droplets, and there is no particular limitation on the dosage form.
  • the dosage form that can be employed in the present invention include a suspension, an emulsion, a solid suspension, a solid emulsion, a powder, a wettable powder, and the like, and preferably a suspension or an emulsion.
  • the suspension of the pesticide formulation of the present invention When the suspension of the pesticide formulation of the present invention is used, the suspension is diluted with water and sprayed, and then the water is volatilized so that the finely divided active pesticide is surrounded by oil droplets.
  • the size of the oil droplets at this time may be large enough to surround the ground pesticidal active ingredient, but preferably the oil droplets have a diameter of 5 to 300 m, more preferably 30 to 300 m. ⁇ 500 ° is desirable.
  • the pesticide formulation of the present invention when an emulsion dosage form is adopted, after dilution and spraying with water, particles in which oil is emulsified adhere to the leaf surface, and after water is volatilized, Many oil droplets in which the pesticidal active ingredient is not finely divided are formed. Even in this state, the pesticide formulation of the present invention shows higher efficacy than the conventional formulation, but when the active pesticide component contains a solid component at room temperature, it may be in this state for several hours to several days. In some cases, if left for several tens of days, crystals of the pesticidal active ingredient will precipitate in the oil droplets, and the oil droplets will surround the fine active ingredient particles, thus exhibiting a long-term high efficacy.
  • the contact angle of the oil droplet is preferably 20 degrees or more.
  • the presence or absence of the formation of oil droplets in the present specification can be easily investigated by the following method.
  • dilute the test sample with water to the spraying concentration for example, when diluting a pesticide formulation containing 5% of pesticide active ingredient by 1000 times, spray 100 ml of distilled water into a JlSllk bottle and then sample 100 1).
  • spray 100 ml of distilled water into a JlSllk bottle and then sample 100 After the addition, slowly add a spatula and stir 50 times to obtain a water dilution of the pesticidal active ingredient).
  • OLYMPUS BH-2 manufactured by OLYMPUS. Observe the condition at 40 ⁇ using an objective lens (Nikon, Nikon Plan4 0.1 160 /-) and an eyepiece (OLYMPUS, OLYMPUS WHK 10 X / 20L).
  • OLYMPUS optical microscope of OLYMPUS BH-2
  • OLYMPUS WHK 10 X / 20L an optical microscope of OLYMPUS BH-2
  • OLYMPUS optical microscope of OLYMPUS BH-2
  • OLYMPUS WHK 10 X / 20L The formation of oil droplets depends on the dilution ratio of water. If the concentration of oil (mineral vegetable oil, etc.) at the time of dilution with water becomes less than 100 ppm, collapse of oil droplets and insufficient surrounding of fine pesticide effective components will occur. Therefore, it is preferable to use 100 ppm or more.
  • FIG. 1 is a micrograph showing a typical state of oil droplet formation in the pesticide formulation of the present invention.
  • the micrograph was taken with a microscope set under the above conditions, taken as a digital image with an image scanner (600 dpi), and then subjected to halftone processing to produce a monoc image.
  • the black bar at the lower left of the drawing is approximately 1 mm.
  • oil droplets are formed. This becomes clearer when compared with FIG.
  • FIG. 5 which was similarly diluted and air-dried using Comparative Example 2 which is a general conventional pesticide formulation.
  • Comparative Example 2 which is a general conventional pesticide formulation.
  • FIG. 5 only a thin film is formed on the slide glass.
  • FIG. 2 shows a microphotograph when Example 5 described later is used, and
  • FIG. 3 shows an enlarged view of a portion A in FIG.
  • oil droplets having a relatively uniform size were formed, but in Fig. 2, oil droplets larger than those existing in other parts were formed at the upper left of the drawing.
  • the size of the oil droplet is not particularly limited, and an oil droplet having a uniform size or an oil droplet having an uneven size may be formed. Some oil droplets have black lumps. This is one in which the pesticidally active ingredient is precipitated, and is a preferred embodiment of the present invention.
  • the preparation of the present invention is used for commonly used plants / pests / fungi, but is particularly effective against plants / pests / "fungi" which have acquired resistance.
  • the plant Z pest / fungus that has acquired the property has a half-lethal concentration of about 10 to 100 times that of the drug, so it is effective if it is not applied more than 10 times the conventional amount and in some cases.
  • the agricultural chemical formulation of the present invention is used, the resistance to the chemical is remarkably reduced, and the pesticide can be sufficiently controlled at the usual application concentration.
  • the effect of attaching the pesticide active ingredient to the receptor is significantly increased, or the concentration of the pesticide active ingredient is extremely high due to the aggregation of the pesticide active ingredient in the oil droplets, and the mortality rate, bactericidal rate, Increase weeding rate It is thought that it is, but it is not certain at present.
  • the oil droplets surround the fine pesticidal active ingredient, and therefore it is preferable to use only a composition that does not destroy this state as the composition of the pesticide formulation.
  • organic bentonite, hydrous amorphous silicon dioxide, etc. which is an inorganic anti-settling agent often used as an anti-settling agent in formulations of pesticidal active ingredients, has a function of preventing sedimentation in this formulation.
  • organic bentonite is added in a large amount, oil enters between the layers of the clay mineral montmorillonite, so that the state where oil droplets surround the active pesticide ingredient is significantly inhibited.
  • hydrous amorphous silicon dioxide absorbs oil into hydrous amorphous silicon dioxide due to its unique oil-absorbing ability, which also has the effect of inhibiting the surrounding of oil droplets.
  • these oil droplet inhibitors can be used as long as they do not destroy the desirable state, for example, by using a very small amount.
  • each component of the pesticide formulation of the present invention will be described.
  • any component as long as oil droplets are formed.
  • the pesticidal active ingredient that can be used in the present invention since the oil droplets exert their effects by enclosing the fine pesticidal active ingredient, their solubility in water is 500 ppm by weight (20) or less, Those which are solid at 0 ° C) are preferred.
  • pesticidal active ingredients that have a solubility in water of 500 ppm or more and are liquid at room temperature can also be adapted when used in combination with the aforementioned pesticidal active ingredients.
  • the active ingredients for insecticides and acaricides include N-tert-butyl-N '-(3,5-dimethylpentyl) -1,5-methyl-6-chromancarpohydrazide (generic name chromafuenozide), N' — Tert-butyl-N '-(4-ethylpentenezyl) -1,3,5-medimethylbenzohydrazide (generic name: tebu Hydrazine-based active ingredients such as phenozide), 1-naphthyl-N-methylcarbamate (generic name: NAC), 2- (ethylthiomethyl) phenyl-methyl carbamate (generic name: ethiofencarp), S—4-pheno Xyloxybutyl dimethylthiocarbamate (generic name: phenothiocalp), 2,3-dihydro-2,2-dimethylbenzofuran-7-yl (
  • the active ingredients of the herbicides are 11- (, ⁇ ; -dimethylpenzyl) 13- (4-methylphenyl) ⁇ rea (generic name: Daimron), 1- (2-cl-lupenzil) 13_ (a, 1-dimethylpentyl) ⁇ rare (generic name: JC-940), o— (3-butyl phenylphenyl) N— (6—methoxy-2-pyridyl) 1-N-methylthiocarbamate (generic name: pyributicarb), 2,4-dichlorophenyl—41 Ditrophenyl ether (generic name: nitrophen), 2,4-dichlorophenyl 3-methoxy-4-nitrophenyl ether (generic name: X—52), methyl 5- (2,4-dichlorophenoxy) 1 2-nitrobenzoate (generic name: bifenox), 2-benzothiazole-2-yloxy_N-methylaceto
  • the oil used in the present invention is not particularly limited, and includes, for example, animal oils such as plant-derived vegetable oils and animal-derived whale oil, and mineral oils.
  • the vegetable oil used in the present invention is not limited.
  • semi-dry oils and / or non-drying oils which are hard to oxidize, are more preferable than drying oils having a large amount of unsaturated carbon, which is oxidized on the leaf surface and the like after carbonization of water, and is liable to solidify. If the oil droplets are extended, they are effectively inferior effectively.
  • Castor oil, soybean oil, and white sesame oil are particularly effective in the present invention.
  • a saturated hydrocarbon liquid paraffin, a paraffin such as a paraffin petroleum, and the like can be mentioned, and if necessary, these may be used alone or in combination. Inspection of non-drying oil and semi-drying oil is carried out using a generally known iodine value, and an iodine value of 150 or less is preferable.
  • the content in the preparation is not particularly limited, but is preferably from 10 to 90% by weight, and more preferably from 30 to 80% by weight.
  • a surfactant for forming oil droplets it is preferable to use a surfactant for forming oil droplets. Any surfactant can be used as long as it has the ability to form oil droplets.However, even if the surfactant does not have the ability to form oil droplets, the diluted water evaporates after spraying the agricultural chemical formulation with water. If an oil droplet can be formed after the formation, it can be used by mixing with a surfactant having a forming ability. Furthermore, when the pesticidal active ingredient is solid at room temperature, it is more preferable to use a surfactant that forms an enclosure of the pesticidal active ingredient particles with oil droplets.
  • the surfactant having the ability to form such oil droplets and the ability to surround the pesticidal active ingredient in the oil droplets include amphoteric surfactants.
  • amphoteric surfactants imidazoline is particularly preferred.
  • examples thereof include an alkylaminocarboxylic acid type, an alkylamino acid type and the like, and among them, an imidazoline type surfactant is particularly preferable.
  • the content of the surfactant is preferably 0.1 to 20% by weight, more preferably 1 to 5% by weight. It should be noted that any surfactant having an oil droplet forming ability can be employed without being limited to the above-mentioned surfactants.
  • surfactants in addition to the amphoteric surfactants described above, various surfactants can be used as long as they do not hinder the formation of oil droplets.
  • a solvent can be used, but in order to produce the pesticide preparation of the present invention in a liquid such as an emulsion, it is essential that water is volatilized after spraying to form oil droplets. However, the boiling point is low and oil droplets are quickly lost, and as a result, crystals are formed, and solvents that are not surrounded by oil droplets cannot be used in the agricultural chemical formulation of the present invention. Therefore, it is preferable to select the most suitable one in consideration of crystallization and solubility depending on the active pesticide to be studied.
  • nitrogen-containing 'sulfur-containing solvents such as N-methylformamide, N-methylpyrrolidone
  • the anti-settling agent and the solidifying agent that can be used in the present invention require that oil droplets surround the fine pesticidal active ingredient.
  • Those having a destructive action are not suitable for use.
  • organic bentonite which is an inorganic anti-settling agent often used as an anti-settling agent in formulations of pesticide active ingredients, hydrous amorphous silicon dioxide, etc. is added in an amount that has the function of preventing sedimentation. Then, in the case of organic bentonite, oil penetrates between the layers of the clay mineral montmorillonite, so that the state in which oil droplets surround the pesticidally active ingredient is significantly inhibited.
  • hydrous amorphous silicon dioxide absorbs oil into hydrous amorphous silicon dioxide due to its unique oil-absorbing ability, which also has the effect of inhibiting the surrounding of oil droplets.
  • these oil droplet inhibitors can be used in a small amount, as long as they do not destroy the desirable condition.
  • those which are suitable as an anti-settling agent and a solidifying agent are preferably water-soluble or dispersed in water and do not adsorb oil, and include, but are not limited to, the following: It is not something.
  • Water-soluble inorganic compounds such as potassium salt, sodium salt, magnesium salt and ammonium salt of hydrochloric acid, sulfuric acid, nitric acid or acetic acid, and further, as organic compounds, xanthan gum, guar gum, sucrose, lactose, dextrin, polyvier alcohol, Examples include crystalline cell mouth, hydroxymethylcellulose, gelatin, sodium alginate, sodium polyacrylate, amino acids, alkenyl succinate esterified starch, etc., and these may be used alone or in combination of two or more. Can be.
  • an antifreezing agent such as propylene glycol and ethylene glycol, a stabilizer such as BHT, a synergist such as piperonyl butoxide, 1,2-benzisothiazolin-3-one, etc.
  • Fungicides, coloring agents, fragrances, etc. can also be added.
  • the agricultural chemical formulation of the present invention can also be packaged in a water-soluble film to prevent the application worker from contacting the active ingredient.
  • Any water-soluble film that can be used in the present invention can be used as long as it comes in contact with and dissolves in water.
  • Specific examples of the water-soluble film that can be used include the following. It is not limited.
  • Polyvinyl alcohol, carboxymethyl cellulose, hydroxya A film obtained from one or more polymers such as tilcellulose, polybutylpyrrolidone, polyacrylic acid or a salt thereof, starch, and gelatin.
  • the thickness of the film is preferably about 20 to: L00 m, more preferably about 30 to 60 xm.
  • the method for producing the pesticide preparation of the present invention will be specifically described below, but is not limited thereto.
  • Oil-based suspending agent (1) Agrochemical active ingredients and, if necessary, surfactants, are dispersed in a dispersion medium such as vegetable oil and z or paraffinic mineral oil by a wet method such as sand grinder mill (Igarashi Kikai Seisakusho Co., Ltd.). A method of crushing to obtain a suspension in oil. (2) A method in which the pesticidal active ingredient is coarsely dry-pulverized in advance with a hammer mill or the like, and then wet-pulverized with a sand grinder mill in the same manner as in (1) to obtain a suspension in oil.
  • a dispersion medium such as vegetable oil and z or paraffinic mineral oil by a wet method such as sand grinder mill (Igarashi Kikai Seisakusho Co., Ltd.). A method of crushing to obtain a suspension in oil.
  • the active ingredients of pesticides are finely pulverized by dry pulverization using a supersonic jet pulverizer (Nihon Pneumatic Industrial Co., Ltd.) or the like, and the fine particles are directly added to a dispersing medium, a surfactant, etc., and stirred to obtain an oil. How to get a medium suspension.
  • Emulsion (4) A method in which a pesticidal active ingredient is dissolved in an appropriate solvent, and then a required amount of a vegetable oil and / or a paraffinic hydrocarbon and a surfactant are added.
  • Susboemulsion (5) Wet milling of pesticidal active ingredients and surfactants in a water solvent using a sand grinder mill (Igarashi Kikai Seisakusho Co., Ltd.), etc., and dispersion of vegetable oil and Z or paraffinic mineral oil in advance A method obtained by adding to a solution prepared by adding a medium and, if necessary, a surfactant.
  • the pesticide preparation of the present invention can be applied by the same method as a general pesticide preparation.
  • the pesticide formulation of the present invention is obtained by diluting an active ingredient of a pesticide to a normal spray concentration onto a slide glass, air-drying the oil, and then forming oil droplets by an oil component. As a result, oil droplets are formed on the leaves of the plant as well as on the slide glass. Also, depending on the pesticidal active ingredient used, the range of application concentration is wide, and it may be difficult to form oil droplets at some concentrations. It is preferable to select a spray concentration at which oil droplets are easily formed.
  • Example 1 Example 1
  • Example 1 Examples of the present invention will be described below, but the present invention is not limited to these.
  • Example 1 Examples of the present invention will be described below, but the present invention is not limited to these.
  • Chromafenozide (purity 95%)-5.5 parts by weight
  • New Calgen D—2 1 2 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene castor oil ether)-5.0 parts by weight
  • Chromafenozide (purity 95%)-5.5 parts by weight
  • Newcalgen D—2 1 2 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene castor oil ether)... 5.0 parts by weight
  • Example 3 (1) was dry-ground with a sample mill, placed in the homogeneous mixture of (2) to (4), and stirred to obtain an oily suspension preparation having an average particle size of 50 m. This product was diluted 1000 times with water, which is a general dilution ratio, and after air-drying, oil droplets were formed around fine crystals considered to be chromaphenozide.
  • Example 3
  • Chromafenozide (purity 95%)-5.5 parts by weight
  • Newcalgen D—2 1 2 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene castor oil ether)-5.0 parts by weight
  • Example 4 (1) was dry-pulverized with a supersonic jet mill, placed in a uniform mixture of (2) to (4), and stirred to obtain an oily suspension having an average particle size of 2.8 m. This product was diluted 1000 times with water, which is a general dilution ratio, and after air-drying, oil droplets were formed around fine crystals considered to be chromafenozide.
  • Example 4
  • Chromafenozide (purity 95%)-5.5 parts by weight
  • New Calgen D_ 2 1 2 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene castor oil ether) ... 0 parts by weight
  • Chromafenozide (purity 95%)-5.5 parts by weight
  • New Calgen D—2 1 2 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxy Ethylene castor oil ether) ... a. 0 parts by weight
  • Chromafenozide (purity 95.8%)-5.5 parts by weight
  • New Calgen D—2 1 2 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene castor oil ether)-5.0 parts by weight
  • Homogenol L95 (trade name, manufactured by Kao Corporation, imidazoline surfactant)... 5.0 parts by weight
  • Chromafenozide (purity 95%)-5.5 parts by weight
  • New Calgen 1 103 D (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene alkyl ether) 8.0 parts by weight
  • New Calgen D 9 3 5 (trade name, manufactured by Takemoto Yushi, Sorbitan Monolate) ... 1.0 parts by weight
  • Homogenol L-95 (trade name, Kao Corporation, imidazoline surfactant) 5.0 parts by weight
  • Chromafenozide (purity 95%)-5.5 1 part by weight
  • Silicone KF56 (trade name, Shin-Etsu Chemical Co., Ltd., silicone foil)
  • New Calgen 1 103 D (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene alkyl ether) ... 0 parts by weight
  • New Calgen D 9 3 5 (trade name, manufactured by Takemoto Yushi Co., Ltd., sorbitan monoolate) * 3.0 parts by weight
  • Homogenol L-95 (trade name, manufactured by Kao Corporation, imidazoline surfactant) 5.0 parts by weight
  • Example 1 (1) was added to (5) and dissolved in a 50 bath, and then the remaining ingredients were added to obtain an emulsion.
  • This product was diluted 1000 times with water, which is a general dilution ratio, and air-dried, and oil droplets were formed. After leaving at room temperature for 1 day, precipitation of crystals thought to be chromaphenozide was observed, and a state in which oil droplets surrounded a fine chromafenozide raw material was observed.
  • Example 1 0
  • Chromafenozide (purity 95%)-5.5 parts by weight
  • Newcalgen D—2 1 2 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene castor oil ether)... 5.0 parts by weight
  • Example 11 (1) was added to (5) and dissolved in a 40 ° C water bath, and then the remaining ingredients were added to obtain an emulsion. This product was diluted 1000 times with water, which is a general dilution ratio, and air-dried, and oil droplets were formed. In addition, after leaving at room temperature for one day, precipitation of crystals thought to be chromaphenozide was observed, and fine chromafofenozide precursors were precipitated, and the state in which oil droplets surrounded the fine crystals was observed.
  • Example 11 Example 11
  • Chromafenozide (purity 95%)-5.5 parts by weight
  • Soybean oil 40.0 parts by weight
  • Newcalgen D—2 1 2 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene castor oil ether)... 10.0 parts by weight
  • Example 1 2 (1) was added to (6) and dissolved in a 40 ° C water bath, and then the remaining ingredients were added to obtain an emulsion. This product was diluted 1000 times with water, which is a general dilution ratio, and air-dried, and oil droplets were formed. After standing at room temperature for one day, precipitation of crystals thought to be chromaphenozide was observed, and fine chromafenozide precursors were precipitated, and the state in which oil droplets surrounded the fine crystals was observed.
  • Example 1 2
  • Chromafenozide (purity 95%)-5.5 parts by weight
  • Newcalgen F S-4 (trade name, manufactured by Takemoto Yushi Co., Ltd., naphthalene polycondensation anionic surfactant) ... 0.28 parts by weight
  • Anti-Home E—20 (trade name, manufactured by Kao Corporation, silicone)... 0.0 3 parts by weight
  • Newcalgen D—2 1 2 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene castor oil ether)... 5.0 parts by weight
  • PROXEL GXL (trade name, manufactured by Zeneca, preservative)... 0 5 parts by weight
  • (1) to (4) were uniformly mixed and wet-pulverized with a sand grinder mill at 1500 rpm for 30 minutes to obtain an oily suspension having an average particle size of 2.5.
  • Ma Separately, (5) to (7) are mixed uniformly, and (8) to (1 1) are also mixed uniformly, and these two liquid mixtures are added to the suspensions (1) to (4). Addition gave an aqueous suspension.
  • This product was diluted 1000 times with water, which is a general dilution factor, and after air-drying, oil droplets were formed around fine crystals that seemed to be chromaphenozide.
  • Chromafenozide (purity 95%)-5.5 parts by weight
  • New Calgen D—2 1 2 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene castor oil ether) 3.5 parts by weight
  • Example 14 (1) to (4) were uniformly mixed and wet-pulverized with a sand grinder mill at 1500 rpm for 30 minutes to obtain an oily suspension preparation having an average particle size of 5. The suspension was adsorbed on (5) to obtain an oily suspension solidified preparation. This product was diluted 1000 times with water, which is a general dilution ratio, and air-dried, and oil droplets were formed around fine crystals considered to be chromaphenozide.
  • Example 14 Example 14
  • Chromafenozide (purity 95%)-5.5 parts by weight
  • Newcalgen D—2 1 2 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene castor oil ether) 3.0 parts by weight
  • Chromafenozide (purity 95%)-5.0 parts by weight
  • Nuicalgen 140 (trade name, manufactured by Takemoto Yushi Co., Ltd., alkylbenzene sulfonate, sorbitan fatty acid ester, polyoxyethylene alkyl ether) — 3.18 parts by weight
  • New Calgen 1 103 D (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene alkyl ether) 0.9 1 part by weight
  • Homogenol L-1 95 (trade name, manufactured by Kao Corporation, imidazoline surfactant)... 2.27 parts by weight
  • Emar 10 powder (trade name, manufactured by Kao Corporation, sodium lauryl sulfate)
  • (1) to (5) were uniformly mixed and wet-milled with a sand grinder mill at 1500 rpm for 30 minutes to obtain an oily suspension preparation having an average particle size of 5.5.
  • the suspension was adsorbed on the mixture of (6) to (8) to obtain an oily suspension solidified preparation.
  • This product was diluted 1000 times with water in a general dilution ratio, and after air drying, formation of oil droplets around fine crystals considered to be chromaphenozide was confirmed.
  • Chromafenozide (purity 95%)-5.5 parts by weight
  • New Calgen D 9 3 5 (trade name, Takemoto Yushi Co., Sorbitan Monolate)... 1.0 parts by weight
  • New Calgen 1 103 D (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene alkyl ether) — 8.0 parts by weight
  • Homogenol L-95 (trade name, manufactured by Kao Corporation, imidazoline surfactant) 3.0% by weight
  • New Esven D (trade name, manufactured by Toyohyun Yokosha, organic bentonite) ••• 3.0 parts by weight
  • Chromafenozide (purity 95%)-5.5 parts by weight
  • New Calgen CP-15-20 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyalkylenearylphenol) 3.0 parts by weight
  • Chromafenozide (purity 95%)-5.5 parts by weight
  • Newcalgen P S—P (trade name, manufactured by Takemoto Yushi Co., Ltd., Nafuren condensed anionic surfactant) ... 0 parts by weight
  • Kunipia F (trade name, manufactured by Kunimine Industries, organic bentonite) ... 0.5 parts by weight
  • PROXEL GXL (trade name, manufactured by Zeneca Corp., preservative) ... 0 5 parts by weight (1) to (7) are uniformly mixed, and wet-pulverized with a sand grinder at 1800 rpm for 50 minutes to obtain an average particle size. 1.0 flowable was obtained. This product was diluted 1000 times with water in a general dilution ratio, and after air-drying, formation of oil droplets around fine crystals considered to be chromafuenozide was not confirmed. The micrograph under the above conditions is shown in FIG. Comparative Example 3
  • Solvesso # 200 (trade name, manufactured by Exxon Co., Ltd., aromatic high-boiling solvent) ... 65.0 parts by weight
  • Newcalgen D—2 1 2 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene castor oil ether) 5.0 parts by weight
  • Homogenol L-1 95 (trade name, manufactured by Kao Corporation, imidazoline surfactant) 5.0 parts by weight
  • Example 18 The above components were uniformly mixed to obtain a 5% diazinon emulsion of the present invention.
  • the drug was diluted to a general dilution factor of 1000 and air-dried. As a result, oil droplets were formed.
  • Example 18
  • New Calgen D—2 1 2 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene castor oil ether)-5.0 parts by weight
  • Example 19 (1) was dry-pulverized with a sample mill, placed in the homogeneous mixture of (2) to (4), and stirred to obtain an oily suspension formulation of the present invention having an average particle size of 5 m.
  • the drug was diluted to a general dilution factor of 1000 and air-dried. As a result, oil droplets were formed.
  • Example 19
  • New Calgen D_2 1 2 (trade name, manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene castor oil ether)-5.0 parts by weight
  • Newcalgen 27 20 S-75 (trade name, Takemoto Yushi Co., Ltd., anionic surfactant)
  • Newcalgen P S-P (trade name, manufactured by Takemoto Yushi Co., Ltd., naphthalene condensed anionic surfactant) ... 0 parts by weight
  • Kunipia F (trade name, manufactured by Kunimine Industries, organic bentonite) ... 0.
  • PROXEL GXL (trade name, manufactured by Zeneca, preservative) Department
  • New Cargen 2 720 S-75 (trade name, Takemoto Yushi Co., Ltd., anionic surfactant)
  • Test example 1 The above components were uniformly mixed to obtain a pesticide emulsion.
  • the drug was diluted to a general dilution of 1000-fold and air-dried. As a result, no oil droplets were formed.
  • Test example 1 The above components were uniformly mixed to obtain a pesticide emulsion.
  • the drug was diluted to a general dilution of 1000-fold and air-dried. As a result, no oil droplets were formed.
  • the reagent is diluted with the other components (white sample) of the test agent excluding the pesticidally effective component, and the white sample dilution is diluted 3000 times with new Gramein (trade name, spreading solution). Diluted 1000-fold. Tea leaves were immersed in the diluent, air-dried, and then drug-resistant cyamaki (Ryakuhamaki, 3rd generation of Makinohara strain bred in Shizuoka Prefecture; hereinafter referred to as R yamahama) was released, and the number of dead insects was examined two days later.
  • Table 3 Basic activity test results for drug-resistant cinnamon
  • the pesticide preparation of the present invention had a stronger basal activity than the comparative example, and exhibited a particularly excellent effect in controlling the resistance of Chiahamaki, which had acquired resistance.
  • Test example 4
  • the reagent is diluted with a white sample (other components of the test agent excluding the drug-effective component), and the diluted white sample solution is diluted 3000 times with new gramin (trade name, spreading liquid). It was diluted twice.
  • An artificial feed manufactured by Nippon Nosan Kogyo Co., Ltd.
  • 10th-instar larvae of Lotus syrup were placed in a plastic cup together with 10 larvae. Two days after treatment, the number of dead insects was examined.
  • Table 4 Results of basal activity test on eight smut beetle Unit: Insect mortality%
  • Example 1 9 100 100 85 25 0 Comparative example 6 25 5 5 0 0 Untreated section 0 0 0 0 0 From Table 4, the basic activity of the agricultural chemical formulation of the present invention also against Lotus syrup Height was indicated. Industrial applicability
  • the pesticide formulation of the present invention has significantly improved basal activity compared to conventional pesticide formulations, and can be expected to have long-term residual effects. Particularly effective against plants / pests that have acquired resistance.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Formulation chimique agricole contenant le principe actif du produit chimique agricole et un ingrédient huileux, caractérisée en ce que, lorsqu’elle est diluée dans l’eau en une concentration adaptée à l’étalement, que le liquide dilué est versé goutte à goutte sur une lame de verre et que l’eau est vaporisée, au moins une partie de l’ingrédient huileux forme une goutte d’huile. La formulation chimique agricole améliore l’efficacité inhérente au produit chimique agricole et confère l’efficacité résiduelle au produit chimique, en ce qui concerne l’efficacité contre l’insecte nuisible.
PCT/JP2004/002274 2004-02-26 2004-02-26 Formulation chimique agricole WO2005082141A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/JP2004/002274 WO2005082141A1 (fr) 2004-02-26 2004-02-26 Formulation chimique agricole

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2004/002274 WO2005082141A1 (fr) 2004-02-26 2004-02-26 Formulation chimique agricole

Publications (1)

Publication Number Publication Date
WO2005082141A1 true WO2005082141A1 (fr) 2005-09-09

Family

ID=34897916

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2004/002274 WO2005082141A1 (fr) 2004-02-26 2004-02-26 Formulation chimique agricole

Country Status (1)

Country Link
WO (1) WO2005082141A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2916651B1 (fr) * 2012-05-18 2019-11-20 BVN Növényvédö KFT Véhicules pour pesticides et procédé pour former un film de pesticide adhérent

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003063908A (ja) * 2001-08-23 2003-03-05 Nippon Kayaku Co Ltd 小川型農薬製剤
JP2003063901A (ja) * 2001-08-23 2003-03-05 Nippon Kayaku Co Ltd 小川型農薬製剤

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003063908A (ja) * 2001-08-23 2003-03-05 Nippon Kayaku Co Ltd 小川型農薬製剤
JP2003063901A (ja) * 2001-08-23 2003-03-05 Nippon Kayaku Co Ltd 小川型農薬製剤

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2916651B1 (fr) * 2012-05-18 2019-11-20 BVN Növényvédö KFT Véhicules pour pesticides et procédé pour former un film de pesticide adhérent

Similar Documents

Publication Publication Date Title
Hayles et al. Nanopesticides: a review of current research and perspectives
JP6339277B2 (ja) 安定な殺有害生物組成物
Knowles Recent developments of safer formulations of agrochemicals
JP5021611B2 (ja) 除草組成物
JP5756023B2 (ja) 安定化された農薬組成物
US8383548B2 (en) Stable mixtures of microencapsulated and non-encapsulated pesticides
JP2022113731A (ja) 腹足類防除剤
Shah et al. Nanotechnology and insecticidal formulations
EP0932339B1 (fr) Agent phytosanitaire solide
KR20130121697A (ko) 마이크로캡슐의 제조 방법
KR20210145122A (ko) 항균 나노 에멀젼
AU2013289339B2 (en) Insecticidal formulations of microcapsules
JP2009013114A (ja) 水田用除草剤および水田の除草方法
JP2749096B2 (ja) 除草剤組成物
JP5026645B2 (ja) 小川型農薬製剤
JPH01197402A (ja) 低毒性水懸乳濁状農薬組成物
ES2356145T5 (es) Formulaciones pesticidas
JP6533808B2 (ja) 有効成分の高負荷水性懸濁製剤
Sabry Role of nanopesticides in agricultural development
WO2005082141A1 (fr) Formulation chimique agricole
JP5025053B2 (ja) 小川型農薬製剤
Priyanka et al. Nanopesticides: synthesis, formulation and application in agriculture
Rehman et al. Application of nanopesticides and its toxicity evaluation through Drosophila model
Krall et al. Overview and challenges of new control agents
Iqbal et al. Vital Role of IPFT in Development of New-Generation Pesticide Formulation for Crop Protection: Advancement Overview in Asian Countries

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase