WO2005074584A3 - Systemes compacts d'analyse d'echantillons et procedes connexes reposant sur des techniques combinees de chromatographie et de spectrometrie de mobilite - Google Patents

Systemes compacts d'analyse d'echantillons et procedes connexes reposant sur des techniques combinees de chromatographie et de spectrometrie de mobilite Download PDF

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Publication number
WO2005074584A3
WO2005074584A3 PCT/US2005/002975 US2005002975W WO2005074584A3 WO 2005074584 A3 WO2005074584 A3 WO 2005074584A3 US 2005002975 W US2005002975 W US 2005002975W WO 2005074584 A3 WO2005074584 A3 WO 2005074584A3
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WO
WIPO (PCT)
Prior art keywords
sample analysis
related methods
analysis systems
mobility spectrometry
spectrometry techniques
Prior art date
Application number
PCT/US2005/002975
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English (en)
Other versions
WO2005074584A2 (fr
Inventor
Douglas B Cameron
David B Wheeler
Quan Shi
Raanan A Miller
Erkinjon G Nazarov
John A Wright
Original Assignee
Sionex Corp
Douglas B Cameron
David B Wheeler
Quan Shi
Raanan A Miller
Erkinjon G Nazarov
John A Wright
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sionex Corp, Douglas B Cameron, David B Wheeler, Quan Shi, Raanan A Miller, Erkinjon G Nazarov, John A Wright filed Critical Sionex Corp
Priority to EP05712422A priority Critical patent/EP1735613A4/fr
Priority to CA002554997A priority patent/CA2554997A1/fr
Publication of WO2005074584A2 publication Critical patent/WO2005074584A2/fr
Publication of WO2005074584A3 publication Critical patent/WO2005074584A3/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/624—Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/025—Gas chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8804—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 automated systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8859—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample inorganic compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

L'invention concerne en règle générale des systèmes, des procédés et des dispositifs à mobilité ionique pour l'analyse d'échantillons, et plus particulièrement, selon certaines variantes, des systèmes compacts GC-MS en mode différentiel, des procédés correspondants, et des techniques de correction des caractéristiques non linéaires dans un analyseur à mobilité ionique.
PCT/US2005/002975 2004-02-02 2005-02-02 Systemes compacts d'analyse d'echantillons et procedes connexes reposant sur des techniques combinees de chromatographie et de spectrometrie de mobilite WO2005074584A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP05712422A EP1735613A4 (fr) 2004-02-02 2005-02-02 Systemes compacts d'analyse d'echantillons et procedes connexes reposant sur des techniques combinees de chromatographie et de spectrometrie de mobilite
CA002554997A CA2554997A1 (fr) 2004-02-02 2005-02-02 Systemes compacts d'analyse d'echantillons et procedes connexes reposant sur des techniques combinees de chromatographie et de spectrometrie de mobilite

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US54109604P 2004-02-02 2004-02-02
US60/541,096 2004-02-02
US55642404P 2004-03-25 2004-03-25
US60/556,424 2004-03-25

Publications (2)

Publication Number Publication Date
WO2005074584A2 WO2005074584A2 (fr) 2005-08-18
WO2005074584A3 true WO2005074584A3 (fr) 2007-02-01

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/002975 WO2005074584A2 (fr) 2004-02-02 2005-02-02 Systemes compacts d'analyse d'echantillons et procedes connexes reposant sur des techniques combinees de chromatographie et de spectrometrie de mobilite

Country Status (4)

Country Link
US (1) US7456394B2 (fr)
EP (1) EP1735613A4 (fr)
CA (1) CA2554997A1 (fr)
WO (1) WO2005074584A2 (fr)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1920243B1 (fr) * 2005-04-29 2015-09-09 DH Technologies Development Pte. Ltd. Procedes, dispositifs et systemes compacts d'analyse d'echantillons bases sur la chromatographie en phase gazeuse et la mobilite ionique
WO2007120373A2 (fr) * 2006-01-26 2007-10-25 Sionex Corporation Analyseur doté d'un spectromètre à mobilité différentielle, dispositif de pré-filtrage, procédés et systèmes correspondants
CA2643354C (fr) 2006-03-16 2016-04-26 Al-Amin Dhirani Procede et systeme de detection dielectrique
EP1865533B1 (fr) * 2006-06-08 2014-09-17 Microsaic Systems PLC Interface isolante micromécanique pour système d'ionisation
US8078427B2 (en) * 2006-08-21 2011-12-13 Agilent Technologies, Inc. Calibration curve fit method and apparatus
US20080091447A1 (en) * 2006-10-16 2008-04-17 Gilmore Eileen T Discrete pest management for public accommodations
NL1033317C2 (nl) * 2007-02-01 2008-08-04 C2V B V Inrichting voor capillaire chromatografie en werkwijze voor het vervaardigen van zo een inrichting.
DE102007017055B4 (de) * 2007-04-11 2011-06-22 Bruker Daltonik GmbH, 28359 Messung der Mobilität massenselektierter Ionen
US7863562B2 (en) * 2007-06-22 2011-01-04 Shimadzu Corporation Method and apparatus for digital differential ion mobility separation
NL1035591C2 (nl) * 2008-06-17 2009-12-18 Concept To Volume B V Verbeterde werkwijze en inrichting voor gaschromatografie.
JP5894798B2 (ja) * 2009-03-04 2016-03-30 ユニバーサル ナノセンサー テクノロジーズ インコーポレーテッド 検出器システム及び方法
ES2401251B2 (es) * 2009-11-11 2014-04-30 Ramem, S.A. Analizador de movilidad diferencial y procedimiento de análisis de la movilidad eléctrica
JP5505224B2 (ja) * 2010-09-16 2014-05-28 株式会社島津製作所 飛行時間型質量分析装置
GB201021360D0 (en) * 2010-12-16 2011-01-26 Thermo Fisher Scient Bremen Gmbh Apparatus and methods for ion mobility spectrometry
US8502138B2 (en) * 2011-07-29 2013-08-06 Sharp Kabushiki Kaisha Integrated ion mobility spectrometer
US20130284913A1 (en) * 2012-04-30 2013-10-31 Baker Hughes Incorporated Process for Monitoring Industrial Fluids and Treatment of Same
MX341071B (es) * 2012-09-21 2016-08-04 Smiths Detection - Watford Ltd Limpieza de fuente de iones de descarga de corona.
US9839756B2 (en) * 2012-11-27 2017-12-12 Resmed Limited Methods and apparatus for ionization therapy
US9310308B2 (en) * 2012-12-07 2016-04-12 Ldetek Inc. Micro-plasma emission detector unit and method
US20160187296A1 (en) * 2013-08-14 2016-06-30 Dh Technologies Development Pte. Ltd. Ion Mobility Method and Apparatus
EP3201939B1 (fr) * 2014-10-02 2021-03-03 908 Devices Inc. Spectrométrie de masse par détection des particules chargées positivement et négativement
US10126278B2 (en) 2016-03-04 2018-11-13 Ldetek Inc. Thermal stress resistant micro-plasma emission detector unit
CN105651896B (zh) * 2016-03-10 2018-04-03 深圳市世纪龙晟科技发展有限公司 一种填充柱方式的pid色谱分析装置
GB2566326A (en) * 2017-09-11 2019-03-13 Owlstone Inc Ion mobility filter
WO2019095053A1 (fr) * 2017-11-15 2019-05-23 Mécanique Analytique Inc. Procédé et appareil d'analyse d'un pic d'élution de chromatographie en phase gazeuse
WO2019144228A1 (fr) 2018-01-23 2019-08-01 Ldetek Inc. Ensemble soupape pour un chromatographe en phase gazeuse
DE112019000840T5 (de) * 2018-03-14 2020-11-12 Hitachi High-Tech Corporation Chromatographie-Massenspektrometrie-Verfahren und Chromatograph-Massenspektrometer
US10782265B2 (en) * 2018-03-30 2020-09-22 Sharp Kabushiki Kaisha Analysis apparatus
SG11202011332QA (en) 2018-05-14 2020-12-30 Mobilion Systems Inc Coupling of ion mobility spectrometer with mass spectrometer
KR102240000B1 (ko) * 2018-08-09 2021-04-14 국민대학교산학협력단 마이크로 가스크로마토그래피 시스템
CN114051428A (zh) * 2019-05-21 2022-02-15 莫比莱昂系统有限公司 用于离子迁移率分离的电压控制
EP3742160B1 (fr) * 2019-05-24 2023-08-09 Sartorius Stedim Biotech GmbH Procédé de chromatographie, procédé de détermination de la concentration d'au moins un composé dans un procédé de chromatographie et procédé d'obtention d'au moins un paramètre de procédé de chromatographie
US11543384B2 (en) 2019-11-22 2023-01-03 MOBILion Systems, Inc. Mobility based filtering of ions
WO2021207235A1 (fr) 2020-04-06 2021-10-14 MOBILion Systems, Inc. Systèmes et procédés de filtrage d'ions bidimensionnel fondé sur la mobilité
JP2023527776A (ja) 2020-05-22 2023-06-30 モビリオン・システムズ，インコーポレイテッド イオンの捕獲および蓄積のための方法および装置
WO2021247820A1 (fr) 2020-06-05 2021-12-09 MOBILion Systems, Inc. Appareil et procédés de manipulation d'ions ayant un cycle de service amélioré
US20220074871A1 (en) * 2020-09-09 2022-03-10 Know Labs, Inc. In vitro sensing methods for analyzing in vitro flowing fluids
US20220074870A1 (en) * 2020-09-09 2022-03-10 Know Labs, Inc. In vitro sensor for analyzing in vitro flowing fluids

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4493207A (en) * 1982-01-19 1985-01-15 Taggents, Inc. Method and apparatus for measuring the rate at which air infiltrates into and out of buildings
US5723861A (en) * 1996-04-04 1998-03-03 Mine Safety Appliances Company Recirculating filtration system for use with a transportable ion mobility spectrometer
US6124592A (en) * 1998-03-18 2000-09-26 Technispan Llc Ion mobility storage trap and method
US6815668B2 (en) * 1999-07-21 2004-11-09 The Charles Stark Draper Laboratory, Inc. Method and apparatus for chromatography-high field asymmetric waveform ion mobility spectrometry

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2615135A (en) 1950-06-20 1952-10-21 Jr William E Glenn Mass analyzing apparatus
US3535512A (en) 1966-07-21 1970-10-20 Varian Associates Double resonance ion cyclotron mass spectrometer for studying ion-molecule reactions
US3621240A (en) 1969-05-27 1971-11-16 Franklin Gro Corp Apparatus and methods for detecting and identifying trace gases
US3931589A (en) 1974-03-21 1976-01-06 The United States Of America As Represented By The Secretary Of The Navy Perforated wall hollow-cathode ion laser
US4025818A (en) 1976-04-20 1977-05-24 Hughes Aircraft Company Wire ion plasma electron gun
US4201921A (en) 1978-07-24 1980-05-06 International Business Machines Corporation Electron beam-capillary plasma flash x-ray device
SU966583A1 (ru) 1980-03-10 1982-10-15 Предприятие П/Я А-1342 Способ анализа примесей в газах
SU1337934A2 (ru) 1986-04-09 1987-09-15 Предприятие П/Я А-1882 Способ анализа примесей в газах
SU1485808A1 (ru) 1987-03-30 1998-06-10 И.А. Буряков Способ анализа микропримесей веществ в газах
SU1627984A2 (ru) 1988-07-20 1991-02-15 Предприятие П/Я А-1882 Способ анализа примесей в газах
DE3914838A1 (de) 1989-05-05 1990-11-08 Spectrospin Ag Ionen-zyklotron-resonanz-spektrometer
US4931640A (en) 1989-05-19 1990-06-05 Marshall Alan G Mass spectrometer with reduced static electric field
US5196039A (en) 1991-01-30 1993-03-23 Southern Illinois University At Carbondale Apparatus and method of multi-dimensional chemical separation
US5135549A (en) 1991-01-30 1992-08-04 The Board Of Trustees Of Southern Illinois University Chromatographic technique and apparatus
GB9116222D0 (en) * 1991-07-26 1991-09-11 Graseby Ionics Ltd Introduction of samples into ion mobility spectrameter
CA2098215A1 (fr) 1992-06-12 1993-12-13 Hideo Ueda Dispositif d'analyse de l'air expire, et methode connexe
US5536939A (en) 1993-09-22 1996-07-16 Northrop Grumman Corporation Miniaturized mass filter
US5420424A (en) 1994-04-29 1995-05-30 Mine Safety Appliances Company Ion mobility spectrometer
US5455417A (en) * 1994-05-05 1995-10-03 Sacristan; Emilio Ion mobility method and device for gas analysis
KR0156602B1 (ko) 1994-07-08 1998-12-01 황해웅 이온이동도 분석기
US5654544A (en) 1995-08-10 1997-08-05 Analytica Of Branford Mass resolution by angular alignment of the ion detector conversion surface in time-of-flight mass spectrometers with electrostatic steering deflectors
US5811059A (en) 1995-10-16 1998-09-22 The United States Of America As Represented By The Secretary Of The Army Automated, on-demand ion mobility spectrometry analysis of gas chromatograph effluents
US5801379A (en) 1996-03-01 1998-09-01 Mine Safety Appliances Company High voltage waveform generator
US5763876A (en) 1996-04-04 1998-06-09 Mine Safety Appliances Company Inlet heating device for ion mobility spectrometer
US5869344A (en) 1996-07-19 1999-02-09 Micromass Uk Limited Apparatus and methods for the analysis of trace constituents in gases
US5838003A (en) 1996-09-27 1998-11-17 Hewlett-Packard Company Ionization chamber and mass spectrometry system containing an asymmetric electrode
US6498342B1 (en) 1997-06-02 2002-12-24 Advanced Research & Technology Institute Ion separation instrument
US6323482B1 (en) 1997-06-02 2001-11-27 Advanced Research And Technology Institute, Inc. Ion mobility and mass spectrometer
US5965882A (en) 1997-10-07 1999-10-12 Raytheon Company Miniaturized ion mobility spectrometer sensor cell
US5789745A (en) 1997-10-28 1998-08-04 Sandia Corporation Ion mobility spectrometer using frequency-domain separation
US6066848A (en) 1998-06-09 2000-05-23 Combichem, Inc. Parallel fluid electrospray mass spectrometer
US6504149B2 (en) 1998-08-05 2003-01-07 National Research Council Canada Apparatus and method for desolvating and focussing ions for introduction into a mass spectrometer
US6713758B2 (en) 1998-08-05 2004-03-30 National Research Council Of Canada Spherical side-to-side FAIMS
WO2000008455A1 (fr) 1998-08-05 2000-02-17 National Research Council Canada Appareil et procede de desolvatation et de focalisation d'ions destines a une introduction dans un spectrometre de masse
US7129482B2 (en) 1999-07-21 2006-10-31 Sionex Corporation Explosives detection using differential ion mobility spectrometry
US7057168B2 (en) 1999-07-21 2006-06-06 Sionex Corporation Systems for differential ion mobility analysis
US6815669B1 (en) 1999-07-21 2004-11-09 The Charles Stark Draper Laboratory, Inc. Longitudinal field driven ion mobility filter and detection system
US6690004B2 (en) 1999-07-21 2004-02-10 The Charles Stark Draper Laboratory, Inc. Method and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry
US7148477B2 (en) 1999-07-21 2006-12-12 Sionex Corporation System for trajectory-based ion species identification
US6512224B1 (en) 1999-07-21 2003-01-28 The Charles Stark Draper Laboratory, Inc. Longitudinal field driven field asymmetric ion mobility filter and detection system
US6806463B2 (en) 1999-07-21 2004-10-19 The Charles Stark Draper Laboratory, Inc. Micromachined field asymmetric ion mobility filter and detection system
US6495823B1 (en) 1999-07-21 2002-12-17 The Charles Stark Draper Laboratory, Inc. Micromachined field asymmetric ion mobility filter and detection system
US7005632B2 (en) 2002-04-12 2006-02-28 Sionex Corporation Method and apparatus for control of mobility-based ion species identification
US6509562B1 (en) 1999-09-16 2003-01-21 Rae Systems, Inc. Selective photo-ionization detector using ion mobility spectrometry
WO2001022049A2 (fr) 1999-09-24 2001-03-29 Haley Lawrence V Nouveau dispositif a mobilite ionique utilisant un analyseur a champ eleve oscillatoire pourvu d'un collecteur de charge a matrice multi-canaux
US6774360B2 (en) 2000-03-14 2004-08-10 National Research Council Canada FAIMS apparatus and method using carrier gas of mixed composition
EP1266209A2 (fr) 2000-03-14 2002-12-18 National Research Council of Canada Spectometrie de mobilite ionique a forme de signal asymetrique haute resolution (faims)/spectrometrie de mobilite ionique en tandem
WO2001069216A2 (fr) 2000-03-14 2001-09-20 National Research Council Canada Dispositif faims a lames a faces paralleles et procede associe
US6639214B1 (en) * 2000-05-09 2003-10-28 Air Products And Chemicals, Inc. Method of improving the performance of an ion mobility spectrometer used to detect trace atmospheric impurities in gases
US6744043B2 (en) 2000-12-08 2004-06-01 Mds Inc. Ion mobilty spectrometer incorporating an ion guide in combination with an MS device
AU2002257177B2 (en) * 2001-04-17 2004-11-25 The Charles Stark Draper Laboratory, Inc. Methods and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry
CN1692279B (zh) 2001-06-30 2012-02-15 西奥奈克斯有限公司 在电场中收集数据和识别未知离子物种的系统
US7119328B2 (en) 2001-06-30 2006-10-10 Sionex Corporation System for DMS peak resolution
US7091481B2 (en) 2001-08-08 2006-08-15 Sionex Corporation Method and apparatus for plasma generation
US7274015B2 (en) 2001-08-08 2007-09-25 Sionex Corporation Capacitive discharge plasma ion source
US6727496B2 (en) 2001-08-14 2004-04-27 Sionex Corporation Pancake spectrometer
US7034286B2 (en) 2002-02-08 2006-04-25 Ionalytics Corporation FAIMS apparatus having plural ion inlets and method therefore
US6787765B2 (en) 2002-02-08 2004-09-07 Ionalytics Corporation FAIMS with non-destructive detection of selectively transmitted ions
CA2493608A1 (fr) 2002-07-25 2004-02-05 Sionex Corporation Procede et appareil pour une commande d'identification d'especes ioniques, fondee sur la mobilite
AU2003249796A1 (en) 2002-09-25 2004-04-19 Ionalytics Corporation Faims apparatus and method for separating ions
AU2003298597A1 (en) 2002-10-12 2004-05-25 Sionex Corporation NOx MONITOR USING DIFFERENTIAL MOBILITY SPECTROMETRY
US7147695B2 (en) 2002-12-13 2006-12-12 New Jersey Institute Of Technology Microfabricated microconcentrator for sensors and gas chromatography
US7223970B2 (en) 2003-09-17 2007-05-29 Sionex Corporation Solid-state gas flow generator and related systems, applications, and methods
JP4802104B2 (ja) 2003-11-25 2011-10-26 サイオネックス コーポレイション サンプルの分析を改善するための分散特性、サンプル解離及び／又は圧力制御を用いた移動度ベースの装置及び方法
EP1697024B1 (fr) 2003-12-18 2017-08-30 DH Technologies Development Pte. Ltd. Procedes et appareil permettant d'ameliorer la detection d'echantillons fondee sur des ions au moyen d'une pre-separation et d'une amplification selectives
WO2005067582A2 (fr) 2004-01-13 2005-07-28 Sionex Corporation Procedes et appareil pour identification d'echantillons amelioree utilisant des techniques analytiques combinees
CA2499247A1 (fr) 2004-03-03 2005-09-03 Ionalytics Corporation Methode et appareil de selection d'entrees dans un systeme faims a entrees multiples
EP1920243B1 (fr) * 2005-04-29 2015-09-09 DH Technologies Development Pte. Ltd. Procedes, dispositifs et systemes compacts d'analyse d'echantillons bases sur la chromatographie en phase gazeuse et la mobilite ionique

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4493207A (en) * 1982-01-19 1985-01-15 Taggents, Inc. Method and apparatus for measuring the rate at which air infiltrates into and out of buildings
US5723861A (en) * 1996-04-04 1998-03-03 Mine Safety Appliances Company Recirculating filtration system for use with a transportable ion mobility spectrometer
US6124592A (en) * 1998-03-18 2000-09-26 Technispan Llc Ion mobility storage trap and method
US6815668B2 (en) * 1999-07-21 2004-11-09 The Charles Stark Draper Laboratory, Inc. Method and apparatus for chromatography-high field asymmetric waveform ion mobility spectrometry

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1735613A4 *

Also Published As

Publication number Publication date
CA2554997A1 (fr) 2005-08-18
WO2005074584A2 (fr) 2005-08-18
US7456394B2 (en) 2008-11-25
US20050230616A1 (en) 2005-10-20
EP1735613A2 (fr) 2006-12-27
EP1735613A4 (fr) 2009-03-11

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