WO2005058285B1 - Tabletas con matriz polimérica emulsionada para emisión controlada de gases y procedimiento para su fabricación - Google Patents
Tabletas con matriz polimérica emulsionada para emisión controlada de gases y procedimiento para su fabricaciónInfo
- Publication number
- WO2005058285B1 WO2005058285B1 PCT/ES2004/000561 ES2004000561W WO2005058285B1 WO 2005058285 B1 WO2005058285 B1 WO 2005058285B1 ES 2004000561 W ES2004000561 W ES 2004000561W WO 2005058285 B1 WO2005058285 B1 WO 2005058285B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tablets
- tablet
- gas
- suitable combination
- acid
- Prior art date
Links
- 239000011159 matrix material Substances 0.000 title abstract 3
- 229920000642 polymer Polymers 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 claims abstract 8
- 239000002253 acid Substances 0.000 claims abstract 6
- 239000003814 drug Substances 0.000 claims abstract 3
- 210000002966 serum Anatomy 0.000 claims abstract 3
- 239000007789 gas Substances 0.000 claims 8
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 5
- 239000000243 solution Substances 0.000 claims 4
- 239000003513 alkali Substances 0.000 claims 3
- 239000002585 base Substances 0.000 claims 3
- 229920001477 hydrophilic polymer Polymers 0.000 claims 3
- 229940102223 injectable solution Drugs 0.000 claims 3
- 239000004033 plastic Substances 0.000 claims 3
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims 2
- 239000000654 additive Substances 0.000 claims 2
- 239000003995 emulsifying agent Substances 0.000 claims 2
- 230000037406 food intake Effects 0.000 claims 2
- LELOWRISYMNNSU-UHFFFAOYSA-N hydrogen cyanide Chemical compound N#C LELOWRISYMNNSU-UHFFFAOYSA-N 0.000 claims 2
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000003921 oil Substances 0.000 claims 2
- 235000019198 oils Nutrition 0.000 claims 2
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 claims 2
- RUVINXPYWBROJD-ONEGZZNKSA-N trans-anethole Chemical compound COC1=CC=C(\C=C\C)C=C1 RUVINXPYWBROJD-ONEGZZNKSA-N 0.000 claims 2
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims 1
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical class S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 claims 1
- 108700020962 Peroxidase Proteins 0.000 claims 1
- 102000003992 Peroxidases Human genes 0.000 claims 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 1
- 239000005844 Thymol Substances 0.000 claims 1
- 206010047700 Vomiting Diseases 0.000 claims 1
- 239000003929 acidic solution Substances 0.000 claims 1
- 230000002378 acidificating effect Effects 0.000 claims 1
- 150000007513 acids Chemical class 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims 1
- 229910052782 aluminium Inorganic materials 0.000 claims 1
- 229940011037 anethole Drugs 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 235000019568 aromas Nutrition 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 239000003637 basic solution Substances 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000010836 blood and blood product Substances 0.000 claims 1
- 229940125691 blood product Drugs 0.000 claims 1
- 229940116229 borneol Drugs 0.000 claims 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000000645 desinfectant Substances 0.000 claims 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000002895 emetic Substances 0.000 claims 1
- 230000002255 enzymatic effect Effects 0.000 claims 1
- 239000011888 foil Substances 0.000 claims 1
- 239000008172 hydrogenated vegetable oil Substances 0.000 claims 1
- 230000000977 initiatory effect Effects 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 235000001510 limonene Nutrition 0.000 claims 1
- 229940087305 limonene Drugs 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 230000000813 microbial effect Effects 0.000 claims 1
- 244000005700 microbiome Species 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- RUVINXPYWBROJD-UHFFFAOYSA-N para-methoxyphenyl Natural products COC1=CC=C(C=CC)C=C1 RUVINXPYWBROJD-UHFFFAOYSA-N 0.000 claims 1
- 230000029058 respiratory gaseous exchange Effects 0.000 claims 1
- 229910000029 sodium carbonate Inorganic materials 0.000 claims 1
- 239000002689 soil Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 238000004659 sterilization and disinfection Methods 0.000 claims 1
- 150000003505 terpenes Chemical class 0.000 claims 1
- 235000007586 terpenes Nutrition 0.000 claims 1
- 229960000790 thymol Drugs 0.000 claims 1
- 230000001988 toxicity Effects 0.000 claims 1
- 231100000419 toxicity Toxicity 0.000 claims 1
- 235000013311 vegetables Nutrition 0.000 claims 1
- 230000002747 voluntary effect Effects 0.000 claims 1
- 239000007762 w/o emulsion Substances 0.000 claims 1
- 238000006911 enzymatic reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/18—Vapour or smoke emitting compositions with delayed or sustained release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/155—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by gas introduced into the reservoir
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Preparation (AREA)
Abstract
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/596,534 US20070092543A1 (en) | 2003-12-18 | 2004-12-17 | Tablets having an emulsified polymer matrix for the controlled emission of gas, and production process |
EP04805104A EP1700595B1 (en) | 2003-12-18 | 2004-12-17 | Tablets having an emulsified polymer matrix for the controlled emission of gas, and production process |
DE602004019684T DE602004019684D1 (de) | 2003-12-18 | 2004-12-17 | Tabletten mit einer emulgierten polymermatrix zur kontrollierten freigabe von gas und herstellungsverfahren |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ESP200302997 | 2003-12-18 | ||
ES200302997A ES2247897B1 (es) | 2003-12-18 | 2003-12-18 | Tabletas con matriz polimerica emulsionada para emision controlada de gases y procedimiento para su fabricacion. |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005058285A1 WO2005058285A1 (es) | 2005-06-30 |
WO2005058285B1 true WO2005058285B1 (es) | 2005-07-28 |
Family
ID=34684846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/ES2004/000561 WO2005058285A1 (es) | 2003-12-18 | 2004-12-17 | Tabletas con matriz polimérica emulsionada para emisión controlada de gases y procedimiento para su fabricación |
Country Status (6)
Country | Link |
---|---|
US (1) | US20070092543A1 (es) |
EP (1) | EP1700595B1 (es) |
AT (1) | ATE423550T1 (es) |
DE (1) | DE602004019684D1 (es) |
ES (1) | ES2247897B1 (es) |
WO (1) | WO2005058285A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103391790B (zh) | 2011-01-28 | 2016-06-15 | 布伦特里实验室有限公司 | 用于肠道清洁的方法、组合物以及包装 |
CN107854479A (zh) * | 2017-12-06 | 2018-03-30 | 朱荣大 | 一种高富氢组合物及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5398850A (en) * | 1993-08-06 | 1995-03-21 | River Medical, Inc. | Gas delivery apparatus for infusion |
JP3522380B2 (ja) * | 1994-05-31 | 2004-04-26 | 花王株式会社 | 浴用剤組成物 |
DE69831940T2 (de) * | 1998-07-30 | 2006-04-20 | Merck Santé | Tablette mit verlängerter Wirkstoffabgabe im Magen |
JP2000051340A (ja) * | 1998-08-12 | 2000-02-22 | Daiichi Shoji Kk | 芳香剤 |
FR2784583B1 (fr) * | 1998-10-16 | 2002-01-25 | Synthelabo | Composition pharmaceutique a residence gastrique et a liberation controlee |
DE19964225C2 (de) * | 1999-12-17 | 2002-01-24 | Henkel Kgaa | Preßverfahren für mehrphasige Formkörper |
CN1193664C (zh) * | 2000-05-17 | 2005-03-23 | 西北农林科技大学无公害农药研究服务中心 | 一种农药泡腾片剂及其制法 |
-
2003
- 2003-12-18 ES ES200302997A patent/ES2247897B1/es not_active Expired - Fee Related
-
2004
- 2004-12-17 US US10/596,534 patent/US20070092543A1/en not_active Abandoned
- 2004-12-17 EP EP04805104A patent/EP1700595B1/en not_active Not-in-force
- 2004-12-17 WO PCT/ES2004/000561 patent/WO2005058285A1/es active Application Filing
- 2004-12-17 AT AT04805104T patent/ATE423550T1/de active
- 2004-12-17 DE DE602004019684T patent/DE602004019684D1/de active Active
Also Published As
Publication number | Publication date |
---|---|
EP1700595B1 (en) | 2009-02-25 |
ES2247897A1 (es) | 2006-03-01 |
DE602004019684D1 (de) | 2009-04-09 |
WO2005058285A1 (es) | 2005-06-30 |
US20070092543A1 (en) | 2007-04-26 |
ES2247897B1 (es) | 2007-05-01 |
EP1700595A1 (en) | 2006-09-13 |
ATE423550T1 (de) | 2009-03-15 |
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